• Korean Journal of Environment and Ecology
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• v.16 no.3
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• pp.249-260
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• 2002

The cultivated lands in metropolitan, such as Seoul, are quasi-natural areas that have been disturbed continuously by human being and is in needs to be preserved and to be managed than to get more crop production in the light of nature experience for civilians through conservation of biodiversity and landscape diversity. However, the cultivated lands in urban areas have decreased rapidly, being changed into developmental areas in its land use. This study is to review change of land use as time change of the cultivated lands in Seoul and to draw the landscape ecological characteristics and structure in the cultivated land after their analysis on the basis of biotope type map in Seoul. The ultimate goal of this study is for development of prototype to enhance biodiversity in urban drypaddy culture area on the results of these analyses.

• Korean Journal of Environment and Ecology
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• v.17 no.1
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• pp.56-70
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• 2003

Reviewing the trend of land use in urban cultivated land, the large part of land has been changed into the high-profit cultivated land of green houses or the developing areas. So, its percent of cultivated land in land use comparing to the other types of cultivated land would get far higher. Therefore, this study aims to identify the characteristics of landscape ecological pattern in the cultivated land of green houses and to find its alternatives for management, which would be a basis of regional planning and management in terms of space and time. The cultivated land of green houses, whose its area reaches 19.3ha, in Seoul are mainly dispersed on the south eastern part of Seoul and its area is larger than the other types of cultivated lands. According to the result of shape index analysis, its perimeters were very simple. Also, Analyzing the first three major neighboring land use to the cultivated land of green houses, the most frequent biotope types of neighboring land use to the cultivated land of green houses were that transportation facility represented 60%, forest, 43%, the other types of cultivated land, 36%, and residential area, 33%. The cause why the percent of transportation facility was higher in the neigh-boring land use types was assumed for the production and distribution of crops. On the basis of the result of landscape ecological pattern analysis, the cultivated land would be managed and contributed to enhance biodiversity and urban environment preservation.

• Polymer(Korea)
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• v.33 no.3
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• pp.237-242
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• 2009

This study examined the transdermal delivery of alendronate across hairless mouse skin. The effects of iontophoresis, perforation with a microneedle, and a combination of a microneedle pretreatment and iontophoresis were evaluated in vitro test. Hydrogel patches were polymerized by UN polymerization to supply a hydrogel patch to the iontophoretic transdermal drug delivery system. The alendronate content in the iontophoretic delivery patch was $5.0\;mg/cm^3$. The amounts of alendronate that permeated across the hairless mouse skin when current densities of 0.25 and $0.50\;mA/cm^2$ were supplied to the iontophoretic alendronate patch were $0.80{\pm}0.03$ and $2.00{\pm}0.02{\mu}g$, respectively. After pretreatment with a microneedle, the amounts of alendronate that permeated across the hairless mouse skin increased to $70.65{\pm}0.37$ and $162.23{\pm}0.40{\mu}g$, respectively. The biocompatibility of the iontophoretic alendronate patch was examined according to the international standardization organization 10993.

• Journal of Hospice and Palliative Care
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• v.21 no.4
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• pp.152-157
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• 2018

Opioid aberrant behavior is an emerging problem as strong opioid is increasingly used to alleviate cancer pain in patients with cancer. Although the treatment of opioid addiction and physical dependence for non-cancer pain is well known, few studies have been conducted with cancer patients, particularly in the Korean population. Presented here are ten cases of cancer patients who were physically dependent on strong opioid and successfully treated with a partial mu-opioid receptor agonist, buprenorphine. This is the first report showing the efficacy of transdermal buprenorphine as a treatment for physical dependence on opioid medication in cancer patients.

• The Korean Journal of Ecology
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• v.26 no.5
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• pp.237-246
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• 2003

A mountain village is defined as that which is autogenously formed over at least 100 years and supported by agricultural yields and forest products and forest area portion of which is over 70% in Guidelines for the Comprehensive Development Planning of Mountain Village. Recently, concerns about management planning of the Green and Eco-Village causes researches related to the Mountain Village's economics, tourism attractiveness, experience programming and investigation of the ecosystem and environment based on the village area. This kind of eco-village project should be supported by ecological evaluation of its spatial structure. But there is rare research of the village spatial structure studied from the ecological viewpoint originally. The purpose of this study is to interpret the spatial structure of Korean mountain village on the landscape ecological paradigm. The paradigm components are patches, corridors, networks, and matrix which explain the land and spatial structure at landscape scale. For this purpose, we selected two case study areas- Sansu and Ajick villages in Gimje city, Jeonlabukdo. We interpreted and evaluated the spatial structure by three steps: (1) to clarify the existing land mosaic pattern by land use mapping (2) to estimate the pore size as development area in matrix (3) to investigate the funnel effect of patch shape. These landscape ecological steps and frameworks could be applied for the proper methodology as fundamentals of eco-village planning and design.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2009.05a
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• pp.112-115
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• 2009

Inter-Prediction is always the main bottleneck in H.264/AVC Baseline Profile. This paper describes an efficient Inter-Prediction hardware architecture design. H.264/AVC decoder supports various block types such as $16{\times}16$, $16{\times}8$, $8{\times}16$, $8{\times}8$, $8{\times}4$, $4{\times}8$, $4{\times}4$ block types. Reference Software(JM) only considers the $4{\times}4$ block type when the reference block is being fetched. This causes duplicated pixels which needs extra fetch cycles. In order to eliminate some of the duplicated pixels, the $8{\times}8$ and $4{\times}4$ block types were considered in the previous design. If the block size is larger than or equal to the $8{\times}8$ block type, it will be separated into several $8{\times}8$ block types and if the block size is smaller than the $8{\times}8$ block type it will be separated into several $4{\times}4$ blocks. For further reduction of the fetch cycles, the various block types are considered in this paper. As a result, the maximum cycle reduction percentage is 18.6% comparing with the previous design.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.10 no.4
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• pp.43-52
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• 1990

Theoretical foundation and algorithms are presented of a new surface modeling and pre-processing system for the three-dimensional structures. The modeling method is based on the boundary representation scheme and composed of two hierarchical model structures: curve-network and surface models. The concept of modeling curve as a union of links is introduced to facilitate surface modeling via various transfinite mapping techniques or Coons Patches. Efficiency and novel aspects of the present method are discussed. Finite element mesh genceration and application procedures will be reported in a later paper.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2010.05a
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• pp.1433-1434
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• 2010

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2010.05a
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• pp.1435-1436
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• 2010

• Polymer(Korea)
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• v.27 no.6
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• pp.536-541
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• 2003

Unsaturated poly(3-hydroxyalkanoate) (UPHA) was biosynthesized and the properties of drug delivery using the polymer matrix were investigated. The biosynthesis of UPHA was carried out by pH-stat fed batch fermentation of Pseudomonas oleovorans (ATCC 29347) grown solely with 10-undecenoic acid as a carbon source. The physical and chemical properties of the biosynethesized UPHA were characterized using NMR, FT-IR, GPC and DSC. The drug release experiments were carried out using HPLC with a diffusion cell fur the release amount of ketoprofen as model drug. The effects of crosslinking degree, patch thickness, and enhancer on the drug release were studied. The drug release rate was linearly decreased and consistent with increased crosslinking degree of the polymer matrix. The duration of drug release was enhanced by the Increased patch thickness. The drug release rate was increased with increased amount of propylene gylcol as an enhancer.