• Proceedings of the Korea Society of Information Technology Applications Conference
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• 2002.11a
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• pp.407-411
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• 2002

Ternary sequences are digital codes consisting of discrete values -1, 0, and 1 only. They are advantageous in that the correlation can be carried out using additions only. Also, they feature an ideal circular autocorrelation function, but in channel characterization tasks, the usual requirement is that the linear autocorrelation function be ideal, i.e., a Kronecker delta function. In this article, we consider two approaches to improving their linear autocorrelation or crosscorrelation properties: one is an inverse filtering method with thresholding, and the other is a singular value decomposition (SVD) method. Both methods are simulated under noisy circumstances. The inverse filtering method resulted in an improvement in peak sidelobe level of about 11 dB at an SNR of 30 dB, and the SVD method showed similar performances, albeit more sensitive to noise depending on the singular value selection strategy.

• Journal of Chest Surgery
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• v.34 no.1
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• pp.64-71
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• 2001

배경: 최근 치료법의 진보에도 불구하고 진행성 식도암의 예후는 5년 생존율이 10% 이하로매우 불량하기 때문에 식도암에 대한 새로운 치료방법의 하나로 암면역 치료가 대두되고 있다. 암면역 치료를 위해서 MAGE 등 종양 특이항원이 연구의 대상이 되고 있으나 국내에서는 아직 이에 대한 연구가 없다. 대상 및 방법: 1995년 1월부터 1998년 12월까지 고신대학교 복음병원 흉부외과에서 수술 치험한 125례의 식도암중 병리조직 보관상태가 양호한 편평세포암 79례를 병기에 따라(1병기 19례, IIa병기 19례, IIb병기 10례, III병기 21례, IV병기 10례) 무작위로 추출하고 대조군으로 평활근종 20례와 정상 식도점막 20례를 대조군으로 하여 DO7 단클론 항체와 항 MAGE-3 단클론 항체 57B를 이용하여 면역조직화학검사를 시행하여 변형 p53 단백과 MAGE-3 유전자 산물의 발현율을 조사하고 식도암 조직에서 질병의 진행도를 반영하는 병기에 따른 발현율 및 변형 p53 단백과 MAGE-3 유전자 산물의 발현율간의 상관관계를 조사하였다. 결과: 식도암조직에서 변형 p53 단백과 MAGE-3 유전자 산물의 발현율은 각각 51.9%, 60.8%의 발현율을 보였으나 식도평활근종과 정상 식도점막에서는 한례도 발현되지 않아 변형 p53 단백과 MAGE-3 유전자 산물은 대조군에 비해 식도암 조직에서 의미있게 발현되었다(p<0.001). 변형 p53 단백과 MAGE-3 유전자 산물의 발현은 I병기에서 68.4%, 52.6%, IIa병기에서 57.9%, 47.6%, IIb병기에서 60%, 70%, III병기에서 33.3%, 71.4%, IV병기에서 40%, 70% 각각 발현되어 병기에 따른 발현율의 차이는 없었다(p=0.193, p=0.452). 식도암 조직내에서 변형 p53 단백과 MAGE-3 유전자 산물의 발현간에는 상관관계가 없는 것으로 나타났다(p=0.679). 결론: 이상의 결과로 변형 p53 단백과 MAGE-3 유전자 산물의 발현은 식도암에서 예후인자로서의 역할은 할수 없으나 식도 편평세포 암조직에서만 특이하게 높은 빈도로 발현됨으로써 식도암도 면역치료의 대상이 될 수 있음을 확인하였다.

• Transactions of the Korean Society of Mechanical Engineers
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• v.16 no.9
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• pp.1643-1653
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• 1992

A method, which uses analytical or numerical modal analysis results, e.g. from finite element analysis, to select desirable response measurement and excitation points for an efficient modal testing is introduced. First, points of master degree of freedom(DOP) are determined so as to statistically minimize errors between responses of a full order model and those estimated from the reduced order model. Such master DOF's are selected as the response measurement points. Then a criterion named 'driving point model constant(DPMC)' related to the magnitudes of resonance peaks of the driving point freqency response functions used to select the point of excitation out of the master DOF's. In this work, the method is demonstrated through applications to modal testing on a one dimensional cantilever beam and an aluminum plate and the results are compared with those by another technique. also, the method is applied to a two dimensional structural component of a passenger car.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.34 no.8
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• pp.41-46
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• 2006

The capability for reconstructing impact forces of an aircraft wing using impact response functions and regularization methods were examined. The impact response function which expresses the relation between the structure response and the impact force was derived using the information on mass and stiffness data of a finite element model for the wing. Iterative Tikhonov regularization method and generalized singular value decomposition method were used to inverse the impact response function that was generally ill-posed. For the numerical verification, a fighter aircraft wing was used. Strain and deflection histories obtained from finite element analysis were compared with the results calculated using impact response functions. And the impact forces were reconstructed with the strain histories obtained from finite element analysis. The numerical verification results showed that this method can be used to monitor impact forces on aircraft structures.

• Journal of Oral Medicine and Pain
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• v.26 no.1
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• pp.87-93
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• 2001

SOX9과 SRY 유전자는 척추동물에서 남성고환의 형성을 유도하는 요소로 알려졌다. SOX9 유전자는 SRY related HMG box gene중 하나로 유전질환의 XY성전환 및 성을 결정하는 데에 관여하며 성결정시기에 그 양에 따른 성전환 발생등 연구가 진행되고 있다. 그러나 이 유전자가 성별판정에 유용할 지는 확실치 않다. 반면 SRY 유전자는 포유동물에서의 배형성시기 고환형성을 결정하는 Y염색체 유전자로 남성에만 존재하고 여성에는 존재 않는다. 현재까지 이을 이용하여 법의학적 검체에서 남성판별에 유용하게 사용되고 있다. 본 실험에서는 X, Y와 같은 성염색체가 아닌 상동염색체상에 있으면서 SRY 유전자와 더불어 남성고환을 결정하는 또다른 요소로서의 기능을 가진 SOX9 유전자를 치아에서 검출하여 법의학적 성별판정에 유용할 수 있는지 알아보고자 본 연구를 수행하였다. 남녀각각 5개의 치아에서 치수와 상아질을 분리한 후 DNA를 추출하여 SOX9과 SRY 유전자의 특이적인 시발체를 제작하고 중합효소연쇄반응을 시행하여 증폭하고 전기영동을 시행하였다. 그 결과 SOX9 유전자는 남녀모두에서 유전자가 검출되었고, SOX9 유전자산물과 SRY 유전자를 혼합하여 사용시 남자에서만 유전자가 검출되었다. 이는 법의치과학적 성별판정에 있어 SOX9 유전자는 사람의 치아에서는 남녀 모두 존재하며 남녀 구별을 위한 성별판정에는 이용할 수 없으며 SRY 유전자와 함께 적용시 남성 특이적 SRY 유전자 검사중 발생할 수 있는 가성 음성 반응여부를 확인하는 데 유용할 것으로 사료된다.

• Journal of Cadastre & Land InformatiX
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• v.50 no.1
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• pp.25-45
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• 2020

The primary purpose of this study is to compare and analyze the performance of local spatial autocorrelation techniques in identifying spatial distribution patterns of green spaces. To achieve the objective, this researcher uses satellite image analysis and spatial autocorrelation techniques. The result of the study shows that the LISA cluster map with the spatial outlier cluster is superior to other analytical methods in identifying the spatial distribution pattern of urban green space. This study can contribute to the related fields in that it uses several different research methods than the existing ones. Despite this differentiation and usefulness, this study has limitations in using low-resolution satellite imagery and NDVI among vegetation indices in identifying spatial distribution patterns of green areas. These limitations may be overcome in future studies by using UAV images or by simultaneously using several vegetation indices.

• The Korean Journal of Applied Statistics
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• v.11 no.2
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• pp.335-350
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• 1998

X11ARIMA is established on the basis of X11 which is one of smoothing approach in time series area and this procedure was introduced by Bureau of Census of United States and developed by Dagum(1975). This procedure had been updated and adjusted by Dagum(1988) with 174 economic index of North America and has been used until nowadays. Recently, X12ARIMA procedure has been studied by William Bell et.al. (1995) and Chen. & Findly(1995) whose approaches adapt adjusting outliers, Trend-change effects, seasonal effect, arid Calender effect. However, both of these procedures were implemented for correct adjusting the economic index of North America. This article starts with providing some appropriate and effective ARIMA model for 102 indexes produced by national statistical office in Korea; which consists of production(21), shipping(27), stock(27), and operating rate index(21). And a reasonable smoothing method will be proposed to reflect the specificity of Korean economy using several moving average model. In addition, Sulnal(lunar happy new year) and Chusuk effects will be extracted from the indexes above and both of effects reflect contribution of lunar calender effect. Finally, we will discuss an alternative way to estimate holiday effect which is similar to X12ARIMA procedure in concept of using both of ARIMA model and Regression model for the best fitness.

• Korean Journal of Ecology and Environment
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• v.54 no.3
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• pp.190-198
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• 2021

Human Aichivirus (Aichivirus A; AiV-A) is a positive-sense single-strand RNA non-enveloped virus that has been detected worldwide in various water environments including sewage, river, surface, and ground over the past decade. To develop a method with excellent sensitivity and specificity for AiV-A diagnosis from water environments such as groundwater, a combination capable of reverse transcription (RT)-nested polymerase chain reaction (PCR) was developed based on existing reported and newly designed primers. A selective method was applied to evaluate domestic drinking groundwater samples. Thus, a procedure was devised to select and subsequently identify RT-nested PCR primer sets that can successfully detect and identify AiV-A from groundwater samples. The findings will contribute to developing a better monitoring system to detect AiV-A contamination in water environments such as groundwater.

• Tribology and Lubricants
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• v.35 no.4
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• pp.229-236
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• 2019

This study investigates the stress singularity that occurs at the contact edge of three bodies in a frictional complete contact. We use the asymptotic analysis method, wherein we constitute an eigenvalue problem and observe the eigenvalue behavior, which we use to obtain the order of the stress singularity. For the present geometry of three bodies in contact, a contact between a cracked indenter and half plane is considered. This is a typical geometry of the PCMI problem of a nuclear fuel rod. Thus, this paper, specifically presents the characteristics of the PCMI problem from the perspective of stress singularity. Consequently, it is noted that the behavior of the stress singularity varies with the difference in the crack angle, coefficient of friction, and material dissimilarity, as is observed in a frictional complete contact of two bodies. In addition, we find that the stress singularity changes essentially linearly with respect to the coefficient of friction, regardless of the variation in the crack angle and material dissimilarity. Concurrently, we find the order of singularity to be 0.5 at a certain coefficient of friction, irrespective of the crack angle, which we also observe in the crack problem of a homogeneous and isotropic body. The order of singularity can also exceed 0.5 in the frictional complete contact problem of three bodies. This implies that the propensity for failure when three bodies are in frictional complete contact can be even worse than that in case of a failure induced by a crack.

• Radiation Oncology Journal
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• v.17 no.1
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• pp.30-35
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• 1999

Purpose : To evaluate the significance of squamous cell carcinoma antigen (SCC) and carcinoembryonic antigen (CEA) as tumor markers in uterine cervix carcinoma. Materials and Methods : In 22 patients with histologically proven primary squamous cell carcinoma of uterine cervix, tumor volume was checked either by using MRI (in 20 patients) or ultrasound (in 2 patients). Pre-treatment serum SCC levels were checked in 22 patients and CEA levels in 21 patients. After curative radiotherapy, post-treatment SCC and CEA were checked regularly. Results : SCC was raised In 68.2$\%$ and CEA was raised in 19.0$\%$ before treatment. The coefficient of correlation between tumor volume and pre-reatment SCC was 0.59382 when one extremely deviated case was excluded. And there was no correlation between tumor volume and CEA. After the treatment, SCC was raised En 9.1$\%$ and CEA was raised in 4.8$\%$. In further follow up measurement, raise of SCC was associated with clinical relapse or persistence of disease. The specificity of raised SCC level in association with recurrent or persistent disease was 93.8$\%$ . The sensitivity in association with recurrent or persistent disease was 100$\%$. The positive predictive values was 85.7$\%$. The median lead time for recurrence was 1.2 months. Conclusions: Both SCC and CEA were good tumor markers for monitoring treatment effect in patients with raised pre-treatment levels. But the sensitivity of pretreatment CEA was low, while that of pretreatment SCC was high. And there was no additional gain by adding CEA measurements to SCC measurements.