• 전기의세계
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• v.9
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• pp.4-10
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• 1962

Relay Servo제어계의 특이한 성질의 하나로, 다른 비선형계에섣 그렇지만 외부의 동작에 의한 것이 아니고, 제어계 자체내의 조건에서 계속적으로 주기적운동, 즉 자려주기진동(Sustained Oscillation)이 발생하는 경우가 있다. 제어계가 자려진동의 상태에 있을 때 그 진폭 및 각주파수는 각 부분의 요소에 의하여 결정되고 고유한 값을 가지게 된다. 이러한 상태는 선형제어계의 입장에서 보며는 불안정상태이나, Relay제어계에서는 이 주기진동이 제어량의 일정목표치에 대한 비율이 미리 규정지은 요구조건에 비하여 실제상 허용할 수 있는 정도면 제어계는 안정하다고 할 수 있다. Relay Servo계의 안정, 불안정은 Describing함수의 방법에 의하여 Nyquist, Attnuation-phase Margin Criteria를 사용하여 Kochenburger, Johnson의 연구에서 규정지었다. Relay-Servo자려진동상태는 제어계의 Gain정수 중에서도 그 종류에 따라 각주파수 및 진폭에 미치는 영향이 달라진다. 본문은 위에 설명한 상태를 알아내기 위하여 간단한 Raly위치제어계를 구성하고 Gain정수를 변화시키면서 자려진동의 각주파수 및 진폭의 변화를 계산하고 기록계의 측정치와 비교검토하고자 한다.

• Proceedings of the Korea Information Processing Society Conference
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• 2000.04a
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• pp.852-854
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• 2000

최근 컴퓨팅 환경의 발달과 함께 영상처리 기술을 이용하여 의료 영상들을 처리하려는 시도가 활발히 진행되고 있다. 백혈병의 경우, 말초 혈액이나 골수 영상을 통하여 백혈구의 수와 모양, 핵의 유무, 핵의 모양 등을 근거로 진단을 내리게 된다. 본 논문에서는 이를 위해 골수 영상으로부터 백혈구 영역을 검출하여 백혈구의 모양과 질감 정보를 이용하여 특이한 성질을 지닌 백혈구를 검출해 내는 시스템을 제안하고 구현하였다. 백혈구의 영역을 검출하기위해서는 입력영상의 RGB 값을 이용한 임계치 방법을 사용하였고, 모양 특징은 이동, 확대/축소, 회전에 불변인 성질을 지닌 UNL Fourier 변환을 사용하였으며, 질감 특징은 Gabor wavelet 변환을 이용하여 추출하였다.

• Tuberculosis and Respiratory Diseases
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• v.45 no.2
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• pp.290-300
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• 1998

Background: CYFRA 21-1 is a tumor marker which measures a fragment of cytokeratin 19 expressed by epithelial cells in bronchus. It is known that cytokeratin 19 is abundant in squamous epithelial cell cancer of the lung. However, if the incidence of elevated serum CYFRA 21-1 level in patients with benign lung diseases or pulmonary tuberculosis with severe parenchymal damage is high the specificity of CYFRA 21-1 could be decreased. The purpose of this study is to investigate the changes of serum CYFRA 21-1 according to the degree of parenchymal damage and the usefulness of CYFRA 21-1 for diagnosing possibly combined lung cancer in patients with pulmonary tuberculosis. Method: We studied the changes of serum CYFRA 21-1 according to the sputum AFB stain, radiologic manifestation and history of treatment in 81 patients with pulmonary tuberculosis, and 20 healthy persons, 25 patients with lung cancer, as a control group. CYFRA 21-1 concentration in serum was quantified by the immunoradiometry assay(Centocor$^{(R)}$). Result: The results were as follow; Serum CYFRA 21-1 level was significantly lower in patients with pulmonary tuberculosis($1.54{\pm}1.19ng/mL$, p<0.01) as compared to patients with lung cancer($12.25{\pm}15.97ng/mL$), and was slightly higher than the level in heathy persons($0.90{\pm}0.49ng/mL$) but there was no significant difference. Serum CYFRA 21-1 level was below the cut-off value of 3.3ng/mL in 95 percent of patients with pulmonary tuberculosis but it was above the cut-off value in 64 percent of patients with lung cancer. Serum CYFRA 21-1 level was significantly higher in the initial treatment group($1.91{\pm}1.55ng/mL$, p<0.05) as compared to the treatment. failure group ($0.92{\pm}0.30ng/mL$). According to the sputum AFB smear, serum CYFRA 21-1 level in patients with negative result was slightly higher than the level in patients with positive result but there was no significant difference. According to the radiologic manifestation, serum CYFRA 21-1 level was significantly higher in patients with infiltrative lesion ($2.15{\pm}1.63ng/mL$, p<0.01) as compared to patients with destructive lesion ($l.04{\pm}0.54ng/mL$). As the size of cavity or destructive lesion was larger, the level was significantly lower(p<0.05). Conclusion: As serum CYFRA 21-1 level was significantly higher in the initial treatment group and patients with infiltrative lesion, it suppose to be closely related with the degree of parenchymal damage of the lung of the pulmonary tuberculosis. However CYFRA 21-1 could be useful method for diagnosing lung cancer even in patients with pulmonary tuberculosis combined with lung cancer because of the fact that it was below the cutoff value of 3.3ng/mL in 95 percent of patients with pulmonary tuberculosis.

• Tuberculosis and Respiratory Diseases
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• v.44 no.4
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• pp.785-795
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• 1997

Background : Tumor markers have been used in diagnosis, predicting the extent of disease, monitoring recurrence after therapy and prediction of prognosis. But the utility of markers in lung cancer has been limited by low sensitivity and specificity. TPA-M is recently developed marker using combined monoclonal antibody of Cytokeratin 8, 18, and 19. This study was conducted to evaluate the efficacy of new tumor marker, TPA-M by comparing the estabilished markers SCC, CEA, Cyfra21-1 in lung cancer. Method : An immunoradiometric assay of serum CEA, sec, Cyfra21-1, and TPA-M was performed in 49 pathologically confirmed lung cancer patients who visited Keimyung University Hospital from April 1996 to August 1996, and 29 benign lung diseases. Commercially available kits, Ab bead CEA (Eiken) to CEA, SCC RIA BEAD (DAINABOT) to SCC, CA2H (TFB) to Cyfra2H. and TPA-M (DAIICHI) to TPA-M were used for this study. Results : The mean serum values of lung cancer group and control group were $10.05{\pm}38.39{\mu}/L$, $1.59{\pm}0.94{\mu}/L$ in CEA, $3.04{\pm}5.79{\mu}/L$, $1.58{\pm}2.85{\mu}/L$ in SCC, $8.27{\pm}11.96{\mu}/L$, $1.77{\pm}2.72{\mu}/L$ in Cyfra21-1, and $132.02{\pm}209.35\;U/L$, $45.86{\pm}75.86\;U/L$ in TPA-M respectively. Serum values of Cyfra21-1 and TPA-M in lung cancer group were higher than control group (p<0.05). Using cutoff value recommended by the manufactures, that is $2.5{\mu}/L$ in CEA, $3.0{\mu}/L$ in Cyfra21-1, 70.0 U/L in TPA-M, and $2.0{\mu}/L$ in SCC, sensitivity and specificity of lung cancer were 33.3%, 78.6% in CEA, 50.0%, 89.7% in Cyfra21-1, 52.3%, 89.7% in TPA-M, 23.8%, 89.3% in SCC. Sensitivity and specificity of nonsmall cell lung cancer were 36.1%, 78.1% in CEA, 50.1%, 89.7% in Cyfra21-1, 53.1%, 89.7% in TPA-M, 33.8%, 89.3% in SCC. Sensitivity and specificity of small cell lung cancer were 25.0%, 78.5% in CEA, 50.0%, 89.6% in Cyfra21-1, 50.0%, 89.6% in TPA-M, 0%, 89.2% in SCC. Cutoff value according to ROC(Receiver operating characteristics) curve was $1.25{\mu}/L$ in CEA, $1.5{\mu}/L$ in Cyfra2-1, 35 U/L in TPA-M, $0.6{\mu}/L$ in SCC. With this cutoff value, sensitivity, specificity, accuracy and kappa index of Cyfra21-1 and TPA-M were better than CEA and SCC. SCC only was related with statistic significance to TNM stages, dividing to operable stages(TNM stage I to IIIA) and inoperable stages (IIIB and IV) (p<0.05). But no tumor markers showed any correlation with significance with tumor size(p>0.05). Conclusion : Serum TPA-M and Cyfra21-1 shows higher sensitivity and specificity than CEA and SCC in overall lung cancer and nonsmall cell lung cancer those were confirmed pathologically. SCC has higher specificity in nonsmall cell lung cancer. And the level of serum sec are signiticantly related with TNM staging.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.23 no.6
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• pp.527-536
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• 2013

In order to predict structural vibration and radiated noise of high-voltage transformer in operation, it is necessary to precisely find the excitation force generated by the coils and core. However, finding the excitation force through experiments of high voltage transformer in operation is not possible. Therefore, this paper deals with identifying the excitation force by using the acceleration data measured through experiments and the transfer function estimated through finite element model. A method to predict structural vibration and radiated noise was also proposed. Three-phase windings and the core are the source of high-voltage transformer. The excitation forces were identified using the acceleration data and the transfer function of the surface of the tank. Structural vibration and radiated noise from the surface of the tank was predicted by using the identified excitation force. As a result of the interpretation of the experimental and computational analysis of structural vibration from the surface of the tank and radiated noise from the field point, the interpretation of the computational analysis showed relatively good accordance with the experiment.

• Bulletin of the Society of Naval Architects of Korea
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• v.26 no.4
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• pp.27-34
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• 1989

A potential-based panel method is formulated for the analysis of a partially cavitating 2-dimensional hydrofoil. The method employs dipoles and sources distributed on the foil surface to represent the lifting and cavity problems, respectively. The kinematic boundry condition on the wetted portion of the foil surface is satisfied by requiring that the total potential vanish in the inner flow region of the foil. The dynamic boundary condition on the cavity surface is satisfied by requiring that the potential vary linearly, i.e., the velocity be constant. Green's theorem then results in a potential-based boundary value problem rather than a usual velocity-based formulation. With the singularities distributed on the exact hydrofoil surface, the pressure distributions are predicted with more improved accuracy than the zero-thickness hydrofoil theory, especially near the leading edge. The theory then predicts the cavity shape and cavitation number for an assumed cavity length. To improve the accuracy, the sources and dipoles on the cavity surface are moved to the newly computed cavity surface, where the boundary conditions are satisfied again. It was found that five iterations are necessary to obtain converged values, while only two iterations are sufficient for engineering purpose.

• Transactions of the Korean Society of Mechanical Engineers
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• v.11 no.6
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• pp.1001-1004
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• 1987

In this study mathematical properties of variational solution and solution of the boundary integral equation of the linear elasticity problem are studied. It is first reviewed that a variational solution for the three-dimensional linear elasticity problem exists in the Sobolev space [ $H^{1}$(.OMEGA.)]$^{3}$ and, then, it is shown that a unique solution of the boundary integral equation is identical to the variational solution in [ $H^{1}$(.OMEGA.)]$^{3}$. To represent the boundary integral equation, the Green's formula in the Sobolev space is utilized on the solution domain excluding a ball, with small radius .rho., centered at the point where the point load is applied. By letting .rho. tend to zero, it is shown that, for the linear elasticity problem, boundary integral equation is valid for the variational solution. From this fact, one can obtain a numerical approximatiion of the variational solution by the boundary element method even when the classical solution does not exist.exist.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.15 no.12
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• pp.2655-2663
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• 2011

Several algorithms have been developed to detect AF which rely either on the form of P waves or the based on the time frequency domain analysis of RR variability. However, locating the P wave fiducial point is very difficult because of the low amplitude of the P wave and the corruption by noise. Also, the time frequency domain analysis of RR variability has disadvantage to get the details of irregular RR interval rhythm. In this study, we describe an atrial fibrillation detection algorithm through non-linear analysis of irregular RR interval rhythm based on the variability, randomness and complexity. We employ a new statistical techniques root mean squares of successive differences(RMSSD), turning points ratio(TPR) and sample entropy(SpEn). The detection algorithm was tested using the optimal threshold on two databases, namely the MIT-BIH Atrial Fibrillation Database and the Arrhythmia Database. We have achieved a high sensitivity(Se:94.5%), specificity(Sp:96.2%) and Se(89.8%), Sp(89.62%) respectively.

• The Korean Journal of Applied Statistics
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• v.27 no.4
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• pp.629-643
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• 2014

It is common to check the validity of an assumed model with the heavy use of diagnostics tools when conducting data analysis with regression techniques; however, outliers and influential data points often distort the regression output in undesired manner. Jang and Anderson-Cook (2013) proposed a graphical method called a firework plot for exploratory analysis that could visualize the trace of the impact of possible outlying and/or influential data points on individual regression coefficients and the overall residual sum of squares(SSE) measure. They developed 3-D plot as well as pair-wise plot for the appropriate measures of interest. In this paper, the approach was extended further to tell the strength of their approach; in addition, a more meaningful interpretation was possible by adding a measure not mentioned in their paper. This approach was applied to the mixture experiment because we felt that a detailed analysis of statistical measure sensitivity is required in a small experiment.

• Journal of Korea Technology Innovation Society
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• v.12 no.3
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• pp.614-637
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• 2009

To enhance the efficiency of national R&D programs, it is the most important thing to establish the optimized evaluation system. This is because the distorted evaluation could be an obstacle to select the best suited research team and lead the desirable research result. In current evaluation process of national R&D program, it is the most frequently used method for eliminating an evaluator's biased view to exclude both the maximum and minimum scores. However, there are several limitations in this stereotype method. Therefore, this study analyzes some real cases to derive the problems from the stereotype method and then recommends the complementary alternatives which can enhance the reliability of the evaluation system for national R&D programs. The results acquired from this study seem to be helpful to increase the agreement of the applicants on the evaluation results and ultimately to maximize the efficiency of national R&D program. In addition, they can be applied to various field with respect to the methodology for ranking decision.