• Journal of Food Hygiene and Safety
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• v.34 no.2
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• pp.183-190
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• 2019

Ursolic acid is recognized for various effects such as anti-cancer, antioxidant, and anti-inflammatory activity. In this study, we confirmed the anti-cancer effect of ursolic acid on human melanoma cancer cells, A375SM and A375P. Survival rate of the melanoma cells was confirmed by MTT assay and the proliferation rate was confirmed by wound healing assay. The rate of apoptotic bodies was confirmed by DAPI staining, and apoptosis rate was confirmed by flow cytometry. The induction of apoptosis protein was examined by western blotting according to the concentration of ursolic acid in melanoma cells. The survival and proliferation rates of melanoma cells were decreased according to the treatment concentrations of ursolic acid. DAPI staining showed that chromosomal condensation of melanoma cells was increased with increasing concentrations of ursolic acid, and increased apoptosis rate of melanoma cells by ursolic acid was confirmed by flow cytometry. We also confirmed by western blotting that cleaved-PARP and Bax were increased and Bcl-2 was decreased at $12{\mu}M$ concentration of uricolic acid in melanoma cells. This study was carried out at low concentrations of ursolic acid, 0 to $20{\mu}M$, and analyzed 24 h after treatment. As a result of this study, it is thought that ursolic acid has the anti-cancer effect through the regulation of apoptosis-related proteins in melanoma cells A375SM and A375P.

• 방재와보험
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• s.75
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• pp.20-22
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• 1997

• 프린팅코리아
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• s.33
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• pp.104-106
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• 2005

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2017.11a
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• pp.3-5
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• 2017

가상 현실 시장은 꾸준한 성장을 하고 있다. 가상 현실 시장이 성장함에 따라 게임 엔진을 이용한 가상 현실콘텐츠 뿐만 아니라 실제 특수 디바이스를 이용하여 촬영한 $360^{\circ}$ 비디오 콘텐츠 시장도 성장하고 있다. 하지만 실제로 촬영한 $360^{\circ}$ 비디오같은 경우 4D 가상 현실 콘텐츠를 즐기기 위해서는 먼저 특수 장치와 $360^{\circ}$ 비디오 간의 이벤트를 정의해야 하는 성가심이 있다. 이러한 불편함을 극복하기 위해 물리적 감각 효과를 일으키는 객체를 인식하고 서술하는 기법을 제시한다. $360^{\circ}$비디오 내의 감각 효과를 일으키는 객체를 인식하고 좌표계 내에 위치를 설정하여 사용자와의 거리가 임계값 이하면 효과를 일으키게 하여 사전에 콘텐츠를 확인하고 감각 효과를 미리 설정하는 번거로움을 없앨 수 있다.

• Journal of Korea Multimedia Society
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• v.12 no.4
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• pp.591-599
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• 2009

The rapid development in computer technology has led to remarkable development in the field of VFX that used in making real picture film. In the past, it was very hard work to make the VFX scenes by means of analogue ways. But these days, CG Animation technology has them make rapid progress and dazzle with brilliance. Recently we can judge the most advanced technology and IT technology based on CG technology introduced in VFX. VFX on CG technology becomes the concentration and the symbol of the most advanced technology. I study manufacturing movement of VFX on CG technology. It shows manufacturing tools are subdivided and the interface is convenient to use, so that artists have applied analogue manufacturing technology easily. The improvement of the computer has made it possible to develop CG technology and tools for hyper-realism. Industries and laboratories in the country get excellent result but we have to concentrate on people in this field more. First of all, we get out of technology copy of Hollywood and we have to develop creative and leading tools reflecting the artists' idea. industry.

• Journal of Digital Convergence
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• v.10 no.10
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• pp.75-83
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• 2012

The aim of this study is to test the behavioral acceptance of adopting smart-media for special education teachers on the points of personal innovativeness and social influence with structural equation modeling(SEM). The corelation of factors such as personal innovativeness, social influence, performance expectancy and behavioral intention are significant. The results of SEM analysis show that the direct impact of social influence on performance expectancy and behavioral intention is significant. The indirect impact of social influence toward behavioral intention through performance expectancy is also significant. However, the personal innovativeness is not statistically significant factor affecting performance expectancy and behavioral intention.

• Journal of the Society of Naval Architects of Korea
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• v.34 no.3
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• pp.27-37
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• 1997

The paper deals with the effectiveness of various special rudders on course stability of a ship. We adopted five types of rudder, such as one normal rudder and four special rudders, which contain two rudders with concave and convex strips on sides respectively, one flapped rudder, and one rudder with end plates on tips. In the circulating water channel, model test was carried out for measuring lift characteristics of the rudders in open water. And various captive model tests were also carried out for measuring the experimental constants related with helm angle and steering in hull-propeller-rudder system. From the test results, the changes in manoeuvring hydrodynamic derivatives due to adoption of normal and special rudders were predicted. Then course stability performances of a ship with normal and special rudders were evaluated and discussed. As a result, it is clarified that the rudder with concave or convex strips and flapped rudder have no effect on course stability, while the rudder with end plates improves course stability with effect. The result in this study is expected to be used usefully when the course stability is in issue and has to be improved without amendment of hull design at initial design phase or after construction of a ship.

• Proceedings of the KIPE Conference
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• 2011.07a
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• pp.34-35
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• 2011

특수 전기자동차 시스템에서는 기존 자동차 대비 차량 동력 특성, 제한된 공간, 시스템 효율 특성으로 인해 다중동력시스템을 주로 적용한다. 본 연구에서는 인버터를 통해 구동한 후 제동시 발생되는 전기에너지 즉, 회생에너지를 이용한 배터리 사용시간 증대의 효과를 가지는 특수 전기자동차의 회생제동 시스템의 구성, 개념도 및 제동원리에 대하여 서술하였다. 제안한 시스템의 검증을 위해 PSIM시뮬레이션을 수행하여 본 논문에서 제안한 회생제동 시스템이 특수 전기자동차에서 유용함을 확인하였다.

• 기계와재료
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• v.21 no.3
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• pp.42-51
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• 2009

원자력/화력 발전소에서 사용중인 터빈출력제어장치(turbine power control device)는 유압 서보액추에이터(hydraulic servo actuator)로 구동하는 특수 스팀 밸브(steam valve)로서 터빈의 속도를 제어하고 스팀을 차단하는 기능이 있다. 대형 발전기(500~1000Mw)를 구동하여 양질의 전기를 생산하기 위해서는 발전기에 연결된 고압 및 저압터빈에 최적량의 스팀을 공급하여야 하고, 고속(화력 3600 rpm, 원자력 1800 rpm)으로 회전하는 터빈이나 스팀계통에 이상이 발생할 경우 터빈의 과속(over speed) 방지를 위하여, 즉시 터빈으로 공급되는 스팀을 차단하여 터빈을 보호해야 한다. 따라서 터빈의 속도제어와 계통의 스팀 량을 감시하여 차단하는 발전소의 특수 밸브의 신뢰성확보기술이 요구된다. 특히 원자력발전소의 경우 핵연료교환주기(약 24개월)에 밸브들을 정비 또는 교체하고 있어 이때마다 시스템과 매칭(튜닝)기술이 요구되었다. 본 연구에서는 전량 수입에 의존했던 원자력/화력 발전소의 특수 밸브인 터빈출력제어장치의 국산화 개발과 신뢰성확보기술 효과에 대하여 논하였다.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.8 no.2
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• pp.163-168
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• 2015

The conventional simple-injection and unilateral-learning methods have the great disadvantages in special education outcomes for intellectual disabilities student. In this paper, we propose a digital micro-mirror system that learners themselves can manipulate the contents by using the various technology on user-interaction and augmented reality. Through the verification tests conducted by special education professionals, it is confirmed that the proposed commercial system can be used as a useful system in the special learning fields requiring high immersion.