• Journal of Life Science
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• v.19 no.10
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• pp.1337-1345
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• 2009

This study investigated the effect of exercise training and garlic powder ingestion on blood lipids and antioxidants activity in rats. Twenty-eight male Sprague Dawley rats were fed a high-fat diet with or without garlic powder (500 mg/kg) for four weeks as grouped in control (CON), exercise (EXE), garlic (GAR), and garlic + exercise training (GAREXE), respectively. EXE and GAREXE were trained on the treadmill for the same periods. Weight of fats (mesentery, perirenal, and epididymal) were weighed and blood glucose, triglycerides (TG), total cholesterol (TC), and high density lipoprotein- cholesterol (HDL-C) were analyzed and low density lipoprotein-cholesterol (LDL-C) was calculated. Malondialdehyde (MDA) and superoxide dismutase (SOD) for lipid peroxidation were analyzed in liver tissue. Body weight in GAREXE was significantly lower in the statistics than that in other groups (p<0.05), and the volume of fat in GAR and GAREXE was also much lower (p<0.05). Blood glucose was significantly lower in EXE and GAR (p<0.05), however, there was no effect of exercise training. Blood TG was lower in GAR and GAREXE (p<0.05), however, there was no effect of exercise training. HDL-C was significantly improved in EXE and GAR compared to CON (p<0.05), and GAREXE was higher than EXE (p<0.05). MDA content was considerably lower in GAREXE compared to EXE (p<0.05), and SOD activity was much higher in other groups compared to CON (p<0.05). In addition, GAREXE was significantly higher than EXE and GAR, thus there was significant increase when a garlic diet was carried out together with exercise (p<0.05). These results suggested that garlic powder ingestion during the training periods had a beneficial effect of lowering glucose and enhancing blood lipids profiles. Moreover, it also has antioxidant effects, which means that it could possibly suppress aging. It is necessary to inspect various effects of garlic with a variety of research methods regarding sampling process, production process, intake method, etc.

• Korean Journal of Applied Biomechanics
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• v.25 no.1
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• pp.113-122
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• 2015

Objective : The purpose of this study was to analyze the foot-pressure distribution of 2D(2 dimensional form) & 3D(3 dimensional form; a customized arch-fit for posture correction) insoles for assessing their biomechanical functionality. Background : Recently there has been increased interest in both foot health and foot pain patients. Analysis of the plantar pressure was often used to solve the problems of the foot displayed by such people as rheumatoid arthritis patients. Method : Subjects who participated in this study were 17 female university students who had no previous injury experience in lower limbs and a normal gait pattern. The shoe size of all subjects was 240 mm. Two models of insoles of 2D(typical flat insole - 2 dimensional form) and 3D(special production - 3 dimensional form) were selected for the test. Using the Pedar-X system and Pedar-X insoles, 4.0 km/h of walking speed, and a compilation of 50 steps walking stages were used to analyze foot-pressure distribution. Results : Results of the foot-pressure distribution and biomechanical functionality on each insole were as follows; analyses of mean plantar pressure, maximum plantar pressure, maximum vertical GRF, and plantar pressure curve shape all showed overall low plantar pressure and GRF. Conclusion : This can be evaluated as an excellent insole for low levels on the plantar pressure and GRF. Therefore, it is possible to conclude that according to this analysis the 3D Customized Arch-fit Insole was better than 2D insole on the basis of these criteria.

• Korean Journal of Applied Biomechanics
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• v.18 no.2
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• pp.115-124
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• 2008

The purpose of this study was to examine the effects of customized foot orthotics on lower extremity muscle activity and fatigue during march in combat boots. Four volunteers with normal foot and five volunteers with excessive pronation foot among soldiers on service were fitted with foot orthotics. The electromyography signal from activity of low extremity muscles were collected with surface electromyography device during walking on the treadmill. The walk on the treadmill was performed with a speed of 4.5 km/h. The experiment design for reseach wes composed two experimentation. The first experiment was to examine the muscle activity of lower extremity between normal foot and excessive pronator foot during march. The second experiment was to examine the muscle activity of lower extremity between wearing orthotics and no wearing orthotics. These data were analyzed by the averaged integral EMG and the mean power frequency. The analyzed results were compared by independent T-test method and paired T-test method of SPSS(windows version 12.0). The result of the study were the muscle activity on pronator foot tend to increase during march but a statistically significant increase in muscle fatigue of vastus lateralis and fibularis longus. A statistically significant decrease in muscle activity of anterior tibialis and fibularis longus and fatigue occurred using the customized foot orthotics in volunteers with excessive pronation foot compared to volunteers with normal foot. Clinically, the application of orthotics for the soldiers with excessive pronation foot appears to delay muscle fatigue and prevent from variable foot injuries. This may contribute to enhancing fighting efficiency.

• Journal of Life Science
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• v.13 no.1
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• pp.21-28
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• 2003

The purpose of this experiment was to compare the energy expenditure and the physiological response among two groups by percent body fat(group A: 30-35% body fat, B: 35-40% body fat) to walking and running at several equivalent speeds. Subjects in group A and B followed A group(mean$\pm$SD, age; 24.0$\pm$0.4yrs, body fat; 32.3$\pm$0.7) and B group (age; 25.2$\pm$0.7yrs, body fat; 36.7$\pm$0.9). The walking and running protocol consisted of treadmill speeds for five min at each of the following speeds: 5.0, 5.5, 6.0, 6.5, 7.0 km.$hr^{-1}$. The obtained data reveal in group A, the rate of oxygen consumption and energy expenditure was higher during walking compared to running ate treadmill speeds $\geq$ 6.6km.$hr^{-1}$. In group 5, the rate of oxygen consumption and energy expenditure was higher during walking compared to running ate treadmill speeds $\geq$ 6.8km.$hr^{-1}$. Heart rates and respiratory exchange ratio were higher at treadmill speeds $\geq$5.8 in group A and $\geq$5.5 in group B. these findings demonstrated that a difference of percent body fat in obese women have no large effect on energy efficiency of walking, but walking within speeds 6.5~7.0km/hr resulted in rates of energy expenditure that were as high or higher than jogging at the same speeds even though the relative stress was greater during walking.

• Food Science and Preservation
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• v.22 no.4
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• pp.598-606
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• 2015

To develop a functional drink using abalone, two abalone composites (APM-1, APM-2) were prepared by mixing the abalone and natural plants (Lycii fructus and Rubus coreanus Miq.). Their antioxidant and anti-fatigue effects were evaluated using rats running on a treadmill after 4 weeks supplementation of the abalone composites. Experimental groups were divided into four groups including normal (non-exercised group), control (exercised group), one dose per day (EAPM-1), and three doses per day (EAPM-2) with exercise by running. Antioxidant activities, and total phenols and flavonoids contents of APM-2 were significantly higher than those of APM-1 (p<0.05). Total lipid content in serum of EAPM-2 was significantly lower than that of control group (p<0.05). Lactate dehydrogenase activity and blood urea nitrogen content of EAPM-1 and EAPM-2 groups were significantly lower than that of control group. There were no significant difference in aspartate aminotransferase activity among control, EAPM-1 and EAPM-2 groups. In the meanwhile, alanine aminotransferase and alkaline phosphatase activities were significantly lower than that of control group. In serum and liver tissues of EAPM-1 and EAPM-2 groups, lipid peroxide contents significantly decreased compared to control group. DPPH radical scavenging activities in liver tissues of EAPM-1 and EAPM-2 groups were significantly higher than those of control group. Therefore, abalone composites were effective for the alleviation of oxidative stress caused by treadmill running, which was dependent on antioxidant activity and phenolic compounds content.

• Journal of Korean Academy of Nursing
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• v.41 no.2
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• pp.197-203
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• 2011

Purpose: This study was done to identify whether pre-conditioning exercise has neuroprotective effects against cerebral ischemia, through enhance brain microvascular integrity. Methods: Adult male Sprague-Dawley rats were randomly divided into four groups: 1) Normal (n=10); 2) Exercise (n=10); 3) Middle cerebral artery occlusion (MCAo), n=10); 4) Exercise+MCAo (n= 10). Both exercise groups ran on a treadmill at a speed of 15 m/min, 30 min/day for 4 weeks, then, MCAo was performed for 90 min. Brain infarction was measured by Nissl staining. Examination of the remaining neuronal cell after MCAo, and microvascular protein expression on the motor cortex, showed the expression of Neuronal Nuclei (NeuN), Vascular endothelial growth factor (VEGF) & laminin. Results: After 48 hr of MCAo, the infarct volume was significantly reduced in the Ex+MCAo group ($15.6{\pm}2.7%$) compared to the MCAo group ($44.9{\pm}3.8%$) (p<.05), and many neuronal cells were detected in the Ex+ MCAo group ($70.8{\pm}3.9%$) compared to the MCAo group ($43.4{\pm}5.1%$) (p<.05). The immunoreactivity of laminin, as a marker of microvessels and Vascular endothelial growth factor (VEGF) were intensively increased in the Ex+MCAo group compared to the MCAo group. Conclusion: These findings suggest that the neuroprotective effects of exercise pre-conditioning reduce ischemic brain injury through strengthening the microvascular integrity after cerebral ischemia.

• Korean Journal of Applied Biomechanics
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• v.19 no.1
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• pp.179-186
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• 2009

This works studied to compare gas analyzer with accelerometer and the estimation of energy expenditure based on different attaching position of tri-axial accelerometer such as waist and top of the foot Based on the fact that oxygen intake increases more radically linearly during walking more than 8.0km/hr. 9 male subjects performed walking and running on the treadmill with speed of $1.5{\sim}8.5km$/hr and $4.5{\sim}13.0km$/hr, respectively. Commercially available Nike + iPod Sports kit was used to compare energy expenditure with sensor module attached to their foot. Actual energy expenditure was determined by a continuous direct gas analyzer and two multiple regression equations of walking and running mode for different attaching position were developed. Results showed that estimation accuracy of energy expenditure using waist mounted accelerometer was higher than that of the top of the foot and Nike + iPod Sports kit. Results of energy expenditure based on waist and top of the foot showed that the crossover state of energy expenditure occurred at 7.5km/hr. But Nike + iPod Sports kit could not find intersection of energy expenditure in all nine subjects. Therefore the sensor module attached to the waist and separate multi regression equation by walking and running mode was the best to estimate more accurate prediction.

• Korean Journal of Applied Biomechanics
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• v.19 no.1
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• pp.159-166
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• 2009

The purpose of this study was to develop and automatic gait event detection algorithm using single accelerometer which is attached at the top of the shoe. The sinal vector magnitude and anterior-posterior(x-axis) directional component of accelerometer were used to detect heel strike(HS) and toe off(TO), respectively. To evaluate proposed algorithm, gait event timing was compared with that by force plate and kinematic data. In experiment, 7 subjects performed 10 trials level walking with 3 different walking conditions such as fast, preferred & slow walking. An accelerometer, force plate and 3D motion capture system were used during experiment. Gait event by force plate was used as reference timing. Results showed that gait event by accelerometer is similar to that by force plate. The distribution of differences were spread about $22.33{\pm}17.45m$ for HS and $26.82{\pm}14.78m$ for To and most error was existed consistently prior to 20ms. The difference between gait event by kinematic data and developed algorithm was small. Thus it can be concluded that developed algorithm can be used during outdoor walking experiment. Further study is necessary to extract gait spatial variables by removing gravity factor.

• The Journal of Korean Physical Therapy
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• v.19 no.4
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• pp.15-24
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• 2007

Purpose: This study was designed to investigate the effects of treadmill exercise on functional recovery after rat with experimental SCI. Methods: SCI was induced by the NYU-spinal cord impactor(NYU, USA) dropped a weight of 10 gm after laminectomy. Experimental groups were divided into the Group I (normal), Group II (control) and Group III(treadmill exercise). After 2 days of the operation, 24 rats(group II, III) were trained to walk on treadmill for 21 days twice/day, 15 min/session. After operation, rats were tested at modified Tarlov scale at 1, 2, 3, 4 days with divided into 2 groups, and Motor behavior test(BBB locomotor rating scale, Grid walking test, Narrow beam crossing test, Modified inclined plane test) was examined at 1, 3, 7, 14 and 21 days. Histopathological study were performed at 1. 3, 7, 14 and 21 days by H&E, Luxol Fast Blue staining were same times. Results: After SCI an improvement of motor behavior was shown group II, III. The motor behavior test of group Ill showed considerable improvement until 14 days. Conclusion: These results suggest that treadmill exercise treatment can playa role in facilitating recovery of locomotion following spinal cord injury.

• Journal of Life Science
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• v.20 no.5
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• pp.805-810
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• 2010

The purpose of this study was to investigate the effect of Sea Tangle supplementation and exercise training on blood glucose and lipid profile in rats. Twenty seven, 4-week old male Sprague-Dawley rats were divided into the control group (C, n=9), sea tangle group (D, n=9) and sea tangle+exercise group (D+T, n=9). Exercise training was performed 5 days a week using a treadmill running program for 6 weeks (5 m/min, 0% grade, 30 min). There was no difference in blood glucose (C: $175.9{\pm}47.5$, D: $173.9{\pm}34.0$, D+T: $165.0{\pm}38.0\;mg/dl$) and triglyceride (C: $251.1{\pm}91.8$, D: $215.0{\pm}90.0$, D+T: $200.0{\pm}89.3\;mg/dl$) among the groups. Total cholesterol value of the D+T group ($81.8{\pm}11.2\;mg/dl$) was significantly lower than that of the C ($103.0{\pm}13.5\;mg/dl$) and D ($102.1{\pm}14.5\;mg/dl$) groups. High density lipoprotein cholesterol (HDL-C) was significantly high in the D+T ($40.9{\pm}9.7\;mg/dl$) group compared with the C ($32.6{\pm}3.8\;mg/dl$) group and D ($31.7{\pm}7.3\;mg/dl$) group. The value of low density lipoprotein cholesterol (LDL-C) for the D ($98.0{\pm}41.0\;mg/dl$) group was statistically lower than the C($114.5{\pm}41.8\;mg/dl$) group, and higher than the D+T ($91.2{\pm}41.7\;mg/dl$) group. In conclusion, sea tangle injection and exercise had a positive effect on blood lipid profiles.