• 건강소식
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• v.35 no.2
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• pp.12-13
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• 2011

어린 시절부터 토끼는 우리에게 친숙한 동물이었다. '토끼와 거북이' 속 토끼는 자기의 실력을 믿고 경주에서 자신보다 느린 거북이게 지고 마는 게으른 토끼로 나타난다. 그런가하면 '별주부전'의 토끼는 임기응변으로 위기를 모면하는 지혜로운 모습으로 그려진다. '이상한 나라의 앨리스'에서 토끼는 앨리스를 환상 속으로 끌어들인다.

• Korean Journal of Animal Reproduction
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• v.27 no.1
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• pp.1-7
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• 2003

Transgenic rabbits were produced by DNA microinjection using growth hormone receptor (GHR) and IGF-1 receptor (IGF-1R) genes fused to metallothionein(MT) promoter. The overall efficiencies for production of transgenic rabbits were 3.2% and 3.1% for GHR and IGF-lR genes, respectively. Founder rabbits transmitted transgenes to their progenies through medelian fashion. Growth rate of GHR and IGF-lR transgenic rabbits was significantly faster than that of non-transgenic rabbits. Transgenic rabbits grew large. (25% and 15% increase in body weight of GHR and IGF-lR transgenic rabbits, respectively) than non-transgenic rabbits and organ weight of transgenic rabbits increased, suggesting that GHR and IGF-1R genes affects growth rates in transgenic rabbits.

• Korean Journal of Animal Reproduction
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• v.25 no.3
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• pp.219-225
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• 2001

To establish rabbit Embryonic Stem (ES) cells, rabbit one-cell embryos were collected and cultured in vitro to blastocysts. Blastocysts were co-cultured with mouse embryonic fibroblasts (MEF), rabbit embryonic fibroblasts (REF) or 570 cells expressing LIF (SNL). Although rabbit ES cells were isolated with low efficiencies, total 8 ES cell lines were kept in vitro with normal colony shape. The MEF was the best feeder for rabbit ES cell isolation in regard to growth rate and undifferentiated morphology. The doubling time of rabbit ES cells in MEF was about 84 hours and the undifferentiated morphology was maintained following passing and freezing processes. These rabbit ES cells were differentiated into embryoid body following the culture in the uncoated dishes, indicating that they were undifferentiated stem cells.

• Journal of Veterinary Clinics
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• v.26 no.6
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• pp.625-627
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• 2009

Treponematosis, called rabbit syphilis, is an infectious disease caused by Treponema cuniculi in rabbits. In this case report, five rabbits were presented with severe crusts in lips, genitalia and nose. Skin scrapings and fungal test were negative. Human syphilis antibody test was positive. The rabbits were treated with penicillin and chloramphenicol for 3 weeks and the crusts were significantly decreased from 5 to 7 days after treatment. No crusts were evident in the rabbits 3 weeks after treatment. These rabbits were cases of treponematosis which showed a favorable therapeutic response by penicillin and chloramphenicol.

• Journal of the korean veterinary medical association
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• v.44 no.7
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• pp.639-648
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• 2008

임상수의사들의 일상적 보고에 의하면 토끼에서 심혈관계 질환의 발생이 점차적으로 증가하고 있는 것을 알 수 있다. 애완동물로서 특히, 실내 애완동물로서의 토끼를 기른 인구의 증가와 더불어 보호자들이 질병의 포착하기 힘든 증상들을 발견하고. 이 글은 체계적인 진단적 접근이 어떻게 향상된 질병관리로 이를 수 있는지 그럼으로써 이런 환축들에게 좀 더 나은 예후를 보장할 수 있는지를 기술하고 있다. 토끼에서 심혈관계 질병의 치료 및 관리에 있어서 초기 단계에서 인식하여 적절한 진단과정을 밟는 것이 매우 중요하다. 이에 토끼에서 발생할 수 있는 심장질병 진단과 치료법 중 수의사가 참고해야할 사항들을 아래 저널에서 번역하여 (In Practice, (2005) 27, 418-425) 기고하는 바 이다.

• Journal of the korean veterinary medical association
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• v.37 no.8
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• pp.706-713
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• 2001

자연적인 서식지에서 토끼는 번번히 육식 동물의 먹이가 된다. 이들의 일차적이고 우선적인 생존 반응은 발견을 피하기 위한 노력으로 조용히 있는 것이다. 토끼는 폭발적인 속도를 빠르게 낼 수 있고 짧은 거리에서 즉시 방향을 바꿀 수 있도록 가벼운 뼈, 작은 앞다리, 강력하고 잘 발달된 뒷다리를 가졌을 뿐만 아니라, 예민한 청각과 즉각적인 후각을 발달시킴으로써 'fight or flight(적자생존)'로 적응해왔다. 이런 생존 반응은 욕구가 없어진 것으로 나타나는 대부분의 집토끼에도 여전히 존재하지만, 이런 토끼들은 장애에 대해 반응이 불완전하고 변화에 쉽게 스트레스를 받는다. 스트레스를 받은 동물은 일차적으로 anorexia와 용변의 빈도와 일관성에 변화를 유발하는 건강, 생식, 행동적인 문제에 더욱 민감하다.

• Journal of Veterinary Clinics
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• v.26 no.6
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• pp.622-624
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• 2009

Psoroptic mites can cause severe pruritic otitis externa with crusts in rabbits. In this case report, three rabbits with a psoroptic mite infestation were treated with a formulation containing 10% imidacloprid and 50% permethrin at a dose of 0.4 ml regardless of body weight. One week after treatment, the rabbits showed mild pruritus with no crusts, mites or eggs. Four weeks after treatment, there were no clinical signs, mites or eggs observed in the rabbits. The rabbits were treated successfully with this combination without adverse reactions for 8 weeks after treatment. This case report suggests that a single topical application of a combination of imidacloprid and permethrin may be an effective and practical treatment for psoroptic mite infestations in pet rabbits.

• Journal of Veterinary Clinics
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• v.32 no.2
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• pp.212-214
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• 2015

Encephalitoozoon cuniculi is an obligate intracellular microsporidian parasite commonly found in rabbits, causing encephalitozoonosis. This organism can also infect a wide range of hosts including humans, which is known to cause opportunistic infections in immunocompromised individuals. In this case, four rabbits presented with head tilt and nystagmus were diagnosed for E. cuniculi infection using ELISA. The rabbits were treated with fenbendazole for 4 weeks and therapeutic success was evaluated by assessing the neurological symptoms. Three out of 4 rabbits showed improved health condition 3 to 5 days after treatment, but one rabbit showed persistent anorexia and head tilt after treatment and then died after 10 days. This report is the first to investigate the therapeutic response of fenbendazole for rabbit encephalitozoonosis in Korea, and suggests that pet rabbits may serve as potential E. cuniculi reservoirs for both pet animals and humans.

• Korean Journal of Veterinary Research
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• v.32 no.3
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• pp.399-402
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• 1992

The causative virus causing rabbit hepatitis has been further characterized by evaluating viral proteins and viral nucleic acids of purified viruses from the liver of the experimentally infected rabbits. Rabbit hepatitis virus has one major structural protein of 54 kilodaltons and some minor proteins. Vrial RNA was resistant to DNAse I. The size of viral nucleic acid of this virus was calculated to be about 7.5 kilobases. These findings indicate that rabbit hepatitis virus belongs to the family Caliciviridae.

• Journal of Veterinary Clinics
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• v.12 no.1
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• pp.849-852
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• 1995

데마슘과 사상균의 일종인 Curvularia lunata가 식물파편으로 오염된 흙에 의해 눈에 외상을 입은 젊은 수토끼(Orytolaggus cunuculis)에서 각막궤양을 일으킨 것으로 밝혀졌다. 이 토끼는 직경 1.5 mm의 각막궤양, 각막부종, 전방축농, 눈물 등을 나타내었다. 각막 소파시료의 KOH 표본과 진균배지에서의 분리를 통해 진균이 확인되었다. 눈의 외상은 진균성각막염의 발생소인이었다. 토끼장의 흙은 Curvularia lunata의 집락을 많이 형성하였으며, 이것이 감염원으로 추정되었다. 이것은 애완용 토끼에서 Curvularia lunata에 의한 안진균증의 최초의 보고인 것으로 판단된다. 외상의 병력이 있는 동물임상의 다양한 상황에서 Curvularia lunata의 병인론적 역할이 연구되어야 함을 강조하였다.