• Title/Summary/Keyword: 칠성

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공진반사광 바이오센서를 이용한 심근경색 마커 감지 기술

  • Heo, Cheol;Kim, Bong-Gyu;Kim, Wan-Jung;Hong, Jong-Cheol;A, Chil-Seong;Kim, Sang-Hyeop;Seong, Geon-Yong
    • Proceedings of the Korean Vacuum Society Conference
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    • 2014.02a
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    • pp.127-127
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    • 2014
  • 인체 내 소량의 생체성분(혈액, 소변 등)을 감지하는 바이오센서 기술은 질병 진단뿐만 아니라 예방 및 관리로 의료서비스 확대, 개인 맞춤형 진료 및 의료비 감소 효과를 가져올 수 있는 기술이다. 광바이오센서는 광학적인 측정방법을 이용하여 다양한 생화학물질들의 상호 반응을 검출해 낼 수 있는 바이오센서로 현재 활발하게 연구가 진행되고 있다. 광 바이오센서는 생체성분 내에 존재하는 전하를 가진 많은 이온들 및 Salt 농도 등에 영향을 받지 않기 때문에 나노 와이어를 이용한 FET (field-effect transistor)형 바이오센서에 비해 많은 장점을 가지고 있다. 일반적으로 광 바이오센서는 형광물질, 인광물질, 발색물질, 방사선 물질 등의 발광물질을 인식물질에 표지하여 인식물질과 분석물질과의 반응유무를 표지된 발광물질의 광학 신호를 감지하여 분석물질을 검출해내는 표지식 광 바이오센서 기술이 상용화되고 있다. 그러나 이러한 분석 방법은 민감도는 우수하지만 분석 시간이 매우 느리고, 고가의 분석 장비 및 복잡한 제조 공정 등의 단점들을 가지고 있다. 이러한 단점들을 극복하기 위하여 생화학 반응 유무를 표지물질 없이 광학적 방식으로 직접 측정할 수 있는 비표지식 광 바이오센서 기술이 최근 들어 많이 연구되고 있다. 본 논문에서는 광파장 이하의 주기를 가진 주기적 공진 격자 표면에서 일어나는 바이오 항원-항체 반응에 대한 공진 반사 파장을 측정하여 생체성분 내에 존재하는 바이오 항원을 고감도로 검출할 수 있는 비표지식 공진반사광 바이오센서 기술을 소개하고자 한다. 공진반사광 바이오센서를 이용하여 human serum내에 존재하는 심근경색 마커인 troponin I (cTnI), creatine kinase MB (CK-MB), myoglobin (MYO)을 0.1 ng/mL 이하의 농도까지 고감도로 측정할 수 있었다.

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Oxygen flooding을 이용한 shallow junction SIMS 분석

  • 이영진;정칠성;박주철;최홍민
    • Proceedings of the Korean Vacuum Society Conference
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    • 2000.02a
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    • pp.171-171
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    • 2000
  • 차세대 반도체 제조에서 Design rule 이 점점 더 shrink 됨에 따라 shallow junction 분석의 중요성이 강조되고 있다. 이러한 shallow junction에 대한 분석방법중의 하나인 SIMS 분석에 있어서 depth resolution을 향상시키는 것이 중요하며, 일차이온의 에너지를 낮추어 줌으로써 이러한 효과를 달성할 수 있다. 그러나 최근의 연구에 따르면 O2+를 이용한 low energy SIMS 분석 시에 non-zero incidence angle로 분석할 경우 surface roughness가 발생한다는 사실이 보고되었으며, surface roughness를 줄이고 분석 초기의 transient region을 줄이기 위한 방법으로 oxygen flooding을 사용하는 경우 특정 각도에서 surface roughness가 여전히 존재할 뿐 아니라 분석 초기영역에서의 sputter rate이 변화하는 문제가 있음이 보고된바 있다. 본 연구에서는 2keV O2+ 일차이온을 이용하여 oxygen flooding 하에서 기존 조건인 60도 incidence로 분석하는 방법의 문제점을 파악하고 incidence angle을 45도로 바꾸어 분석하는 방법을 검토하였다. 그 결과 기존의 분석조건에서는 분석도중 표면부근에서 sputter rate이 변화하고 surface roughness가 증가하는 것을 확인하였고, 그로 인하여 oxygen flooding을 하지 않은 경우와 많은 차이가 발생하는 것을 발견하였다. Incidence angle을 45도로 바꾼 결과 이러한 문제가 해결되는 것을 확인하였으며, 특히 GaAs $\delta$layer 분석을 통하여 이 분석조건이 기존의 분석조건에 비하여 획기적으로 향상되는 것을 확인 할 수 있었다. 또한 여러 가지 shallow junction 분석을 통하여 이 분석방법이 상당히 신뢰성이 있음을 알 수 있었다. 그러나 여전히 oxygen flooding을 하지 않은 경우에 비하여 다소간의 차이가 있는 것이 발견되었는데, 이는 주로 표면에 잔존하는 산화막에 의한 효과와 oxygen flooding에서 보다 더 depth resolution이 좋음으로 인하여 발생하는 것으로 추정되었으며 그 밖에 다른 가능성도 제기되었다. 따라서 이 방법은 표면 산화막이 거의 없는 시료에 대하여 적용한다면 oxygen flooding을 하지 않은 경웨 비하여 transient region이 거의 없고 junction depth를 보다 신뢰성 있게 측정할 수 잇는 장점이 있는 것으로 판단되었다. As, P의 저 에너지이온 주입시료에 대해 이 분석방법을 적용할 경우 C+s 분석법에 비하여 depth resolution을 비교적 쉽게 향상시킬 수 있었고, oxygen follding을 쓰지 않은 경우에 비해서는 검출한도를 약 100배 정도 향상시킬 수 있었다. 그러나 2.5keV Cs+ 분석법에 비하면 아직 depth resolution이 불충분하여 실제로 shallow As 분석에 적용하기에는 다소 문제점이 있었다.

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Comparison of Quality Stability of Rice and Rice Flour during Storage (쌀 및 쌀가루 저장중 품질 안정성의 비교)

  • Kim, Byeong-Sam;Park, Noh-Hyun;Jo, Kil-Suk;Kang, Tong-Sam;Shin, Dong-Hwa
    • Korean Journal of Food Science and Technology
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    • v.20 no.4
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    • pp.498-503
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    • 1988
  • Rice and rice flour were stored at $13^{\circ}C$, room temperature$(17-28^{\circ}C)$ and $38^{\circ}C$ for six months and the changes in physicochemical and organoleptic qualities were investigated to determine the preservability. Fat acidity increased rapidly up to 60 days at room temperature and 45 days at $38^{\circ}C$ and thereafter it increased slowly. At $13^{\circ}C$, it increased constantly and slowly throughout the storage. In the changes of Hunter's color for the rice and rice flour, L-value was decreased, but ${\Delta}\;E-Value$ was increased. In amylograph properties, initial pasting temperature, maximum viscosity and breakdown were all increased. Quality of stored rice was a little superior to rice flour, but there were not significantly different among them.

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Natural Enemies of Citrus Red Mite, Panonychus citri McGREGOR, and Seasonal Occurrence of Major Predators on Yuzu tree (Citrus Junos) (유자에서 귤응애의 천적종류와 주요종의 발생소장)

  • 김규진;최덕수
    • Korean journal of applied entomology
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    • v.39 no.1
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    • pp.13-19
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    • 2000
  • This studies was carried out to investigate the natural enemies of citrus red mite, pononychus citri and seasonal occurrence of its major beneficial insects in Yuzu groves (Chonnam province) from 1996 to 1998. Natural enemies against citrus red mite were 9 species including Oligota kashmirica benifica, 0. yasumatsui, Stethorus punctillum, Chrysopa pallens, Propylea japonica, Orius sauteri, Scolothrips takahashii, Amblyseius womersleyi and one unidentified species of thrips (Family: Phlaeothripidae). Among them, Oligota kashmirica benzficu and Stethorus punctillum were found to be dominant species. 0 . kushmirica henifica had 4-5 generations from middle May to middle November with peak in early September. S. punctillum had 3 generations from late May to late October with peak of late June to middle July. Population dynamics between predator ( 0 . kushmiricu benifica and S. punctillum) and prey (Panonychus citri) were quite well synchronized until September but predator density was decreased abruptly after October.

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Taxonomic Revision of the Suborders Blennioidei and Zoarcoidei (Pisces, Perciformes) from Korea (한국산 베도라치아목과 등가시치아목(농어목) 어류의 분류학적 재검토)

  • 김수익;강언종
    • The Korean Journal of Zoology
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    • v.34 no.4
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    • pp.500-525
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    • 1991
  • 1986년부터 1991년까지 우리나라 연안에서 채집된 베도라치아목 Blennioidei과 등가시치아목 Zoareoidei의 어류 표본을 대상으로 분류학적으로 재검토하였다. 베도라치아목 어류는 먹베도라치과 Tripterygiidae의 가막베도라치 Enneoptewgius etheostomus(Jordan et Snyder) , 비늘 베도라친과 Labrisomidae의 비늘베도라치 감eoclinus bwope(4ordan et Snyder) , 그리고 청 베도라치과 B1enniidae의 청베도라치 Pictiblennius yotobei(Jordan et Snyder), 저울베도라치Entomacrodus stellifer lighti(Herre), 대강베도라치 Istibfennius enosimae(Jordan et Snyder), 앞동갈베도라치 Omobranchus elrgons(Steindachner), 골베도라치 O. punctatus (Valenciennes) 및 두줄베도라치 Petroscines breuiceps(Valenciennes)의 7속 8종으로 분류되었다. 이 가운데 N. bwope의 표본은 우리나라에서는 본 조사기간 중 제주도 연안에서 처음으로 확인되어 한국 미기록종으로 보고한다. 한편 등가시치아목의 어류는 등가시치란 Zoarcidae의 벌레문치 Lycodes tanakoi Jordan et Thompson, 먹갈치 Lycodes nakamurai Tanaka, 등가시치 Zoarces gilrii Jordan et Starts, 실베도라치 Zoarchias aculeatus( Basilewsky), 우베도라치 Zoarchias uchidai Matsubara, 민베도라치 Zoarchias glaber Tanaka, 얼룩가시치 Neozoarces pulcher Steindachner, 칠성갈치 Petroschmidtia toyamensis Katayama, 자갈치 Gvmnelopsis brashnikoui Soldatov, 문자갈치 Dauidijordania poecilimon(Jordan et Fowler) 및 청자갈치 Allolepis hollandi Jordan et Hubbs, 장갱이란 Stichaeidae의 세줄베도라치 식nogrammus hewagrammus(Temminck et Schlegel), 장갱이 Stichaeus grigorjemi Her\ulcornerenstein, 왜도라치 Chri'olophis wui(Wang et Wang ) , 괴도라치 Chirolophis joponicus(Jordan et snyder) , 벼슬베도라치 각ectrias benjamini Jordan et Snyder, 가시베도라치 Lumpenella nigricons Matsubara, 육점날개 Ophistocentws zonope jordan et Snyder, 그물베도라치 Dictyosoma burgeri Van der Hoeven 및 황점 베도라치Dictyosoma wbrimaculata Yatsu, Yasuda et Taki, 그리고 황줄베도라치란 Pholididae의 황줄베도라치 Phoris taczanowskii(Steindachner), 오색베도라치 Phoris omotus (Girad), 베도라치 Pholis nebuloso(Temminck et Schlegel), 횐베도라치 Pholisfangi(Wang et Wang) 및 점베도라치 Pholis crossispino(Temminck et Schlegel)의 17속 25종이 분류되었다. 이중에서 Zoarchias glaber, Chirofophis oui, Alectrias benjamini, Dictyosoma mbrimaculamia 및 Pholis crassispina의 5종은 한국 미기록종으로 보고한다. 아울러 이들 미기록종을 포함한 한국산 베도라치아목과 등가시치아목 어류의 속 .종 검색선 와 종별 사진을 제시하고, 이들 표본을 근거로 하여 형태적 특징, 계수계측치, 채집지 및 서식처를 기록하였으며, 이들의 분류학적 위치에 대해 논의하였다. 우리나라에 출현하는 베도라치아권의 어류는 거의 대부분이 제주도 연안과 서남해 연안에 제한분포하는데, 등가시치아목의 어류는 주로 동해연안에서 많은 종이 출현하고 있어서 동물지리학적으로 주목된 다.

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Clinical and histopathological study on the effect of Nonresorbable membrane with Demineralized freeze dried bone graft for Guided Bone Regeneration in Implant Dehiscence Defects (매식체 주위 열개형 골결손부에서 차단막과 골 이식술의 사용이 골 형성에 미치는 영향에 대한 임상 및 조직병리학적 연구)

  • Kwon, Chil-Sung;Hong, Ki-Seok;Lim, Sung-Bin;Chung, Chin-Hyung;Lee, Chong-Heon
    • Journal of Periodontal and Implant Science
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    • v.35 no.3
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    • pp.687-702
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    • 2005
  • The purpose of this study is to examine the effect of non-resorbable membrane such as e-PTFE which was used with DFDB in bone regeneration on dehiscence defect in peri-implant area. Amomg the patients, who have recieved an implant surgery at the department of Periodontics in Dan Kook University Dental Hospital, 12 patients showed implant exposure due to the dehiscence defect and 15 implants of these 22 patients were the target of the treatment. Periodontists randomly applied $Gore-Tex^{(R)}$ to the patients and treated them with antibiotics for five days both preoperatively and postoperatively. Reentry period was 26 weeks on average in maxilla and 14 weeks on average in mandible. The results were as follows : 1. Dehiscence bone defect frequently appeared in premolar in mandible and anterior teeth in maxilla respectively. 2. Among 15 cases, 1 membrane exposure was observed and in this case, regenerated area was decreased. 3. In non-resorbable membrane, bone surface area $9.25{\pm}4.84$ preoperatively and significantly increased to $11.48{\pm}7.52$ postoperatively(0.05). 4. The increase of bone surface area in non-resorbable membrane was $2.23{\pm}3.38$. 5. As a result of histopathological finding, DFDB surrounded by new bone formation and lamellate bone, resorption of DFDB and bone mineralization was found. Also, fibrosis of connective tissue beneath the membrane was found. This study shows that the surgical method using DFDB and non-resorbable membrane on dehiscence defect in peri-implant area is effective in bone regeneration.

Analysis of Wooden Materials and Fabrics from the Tomb of Yi Jing (이징(1580년~1642년) 묘 출토 목질류 및 직물류 분석)

  • Lee, Hyosun;Park, Woonji
    • Conservation Science in Museum
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    • v.18
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    • pp.19-34
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    • 2017
  • Analysis of the species of wood in the wooden materials and the chemical composition of the fabric of the clothing excavated from the tomb of Yi Jing (1580-1642) has determined that the wooden materials, including the coffin (內棺, naegwan), burial chamber(外棺, oegwan), chilseongpan(七星板, bottom-lining board), and fan-shaped slats were made of pine(Pinus densiflora). The analysis of the fabrics suggested that the cloth attached to the fan-shaped slats, the funeral banner with inscriptions, and the five pouches for the corpse (五囊, onang) were all made of silk. The jacket was made of plain-weave cotton, while the inner and outer cloth of the socks were made of cotton and hemp, respectively. Among the silk items, the pouches for the left and right feet (constituting the five pouches for the corpse) were made from a satin-weave figured silk, while the other silk items were made of ju(紬), or plain-weave silk fabric. Infrared analysis revealed that the fan-shaped slats were decorated with cloud patterns across the entire surface, while the funeral banner and the five pouches for the corpse bore ink inscriptions.

Fabrication and Evaluation of Al Targets using the SPS Technique and their Sputter Fabricated Films (방전플라즈마 소결법에 의해 제조된 Al 타겟과 스퍼터링 박막의 특성평가)

  • Hyun, Hye Young;Kim, Min Jung;Yoo, Jung Ho;Jeong, Chil Seong;Yang, Jun-Mo;Oh, Ik Hyun;Park, Hyun-Kuk;Lee, Seung Min;Oh, Yong Jun
    • Korean Journal of Metals and Materials
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    • v.49 no.6
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    • pp.493-497
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    • 2011
  • The basic properties and electrical characteristics of sputtering films deposited with a commercial cast target and spark plasma sintering (SPS) were compared and analyzed. The results, revealed that, the Al film prepared by heating at $60^{\circ}C/min$ (SPS process) showed a specific resistance similar to the commercial cast Al film. In addition, the results of XRD, SIMS and TEM, showed that there was not much difference in the crystal structure and impurities between the two films. Consequently, the SPS Al target was found to have properties quite similar to the commercial one and it is expected to be applied in future research to the metal wiring material for semiconductor/display devices.

Classification of Rice Cultivar Using Two-dimensional Ordination Analysis (Two-dimensional Ordination 분석법에 의한 수도 품종 분류)

  • Soon-Chul Kim
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.34 no.1
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    • pp.74-80
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    • 1989
  • Twentyseven rice cultivars were compared Quantitatively and classified by 15 agronomic traits. For this, 12 Tongil-type rice cultivars and 15 Japonica-type rice cultivars were transplanted at the experimental farm of the Yeongnam Crop Experiment Station on May 25 in 1987. Jangseongbyeo belonging to Tongil-type had the greatest dissimilarity total among 27 rice cultivars and followed by Chilseongbyeo, Gayabyeo, Hangangchalbyeo, Gihobyeo (Tongil-type) and Sangpoongbyeo (Japonica-type) while cultivars having greatest similarity total were Daecheongbyeo and Yeongsanbyeo and followed by Nagdongbyeo, Sinsunchalbyeo, Gwangmyeongbyeo, Yeongdeogbyeo, Palgongbyeo and Dongjinbyeo that were all belonging to Japonica-type cultivars. CuItivar pairs having the greatest dissimilarity coefficient (50-55%) were combinations of Gayabyeo and Sangpungbyeo, Gihobyeo, or Seonambyeo, combinations of Chilseongbyeo and Jangseongbyeo, Sangpung-byeo, Chucheongbyeo, Gihobyeo or Seonambyeo and combinations of }angseongbyeo and Gwangmyeong-byeo, Sangpungbyeo, Gihobyeo, Daechangbyeo or H waseongbyeo. On the other hand, cultivar pairs having the greatest similarity coefficient (above 85 %) were combinations of Dongjinbyeo and Sinsunchalbyeo, Daecheongbyeo, Somjinbyeo or Yeongsanbyeo, combination of Sangpungbyeo and Gihobyeo, combinations of Yeongdeogbyeo and Yeongsanbyeo or Palgongbyeo, combination of Gwangmyeongbyeo and Yeongdeogbyeo, Combinations of Nagdongbyeo and Gwangmyeongbyeo, Yeongdeogbyeo, Daecheongbyeo, Hwaseongbyeo or Yeongsanbyeo, combinations of Sinsunchalbyeo and Daecheongbyeo or Yeongsanbyeo, combinations of Somjinbyeo and Daecheongbyeo or Yeongsanbyeo and combination of Daecheongbyeo nd Yeongsanbyeo. Two-dimensional ordination analysis method provided the information on cultivar classification between Japonica-type and Tongil-type cultivars except a few cultivars. Only two cultivars, Joongweonbyeo and Seomjinbyeo were located opposit area that implied Tongil-type cultivar Joongweonbyeo was rather close to Japonica-type while Japonica-type cultivar Seomjinbyeo was rather close to Tongil-type, respectively. Sinsunchalbyeo and Daecheongbyeo, on the other hand, were located on the line between two cultivar groups. The method of two-dimensional ordination analysis concluded as feasible approach to classify cultivars Quantitatively for the practical purpose.

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Influence of Fertilizer Levels and Cultivated Regions on Morphological Characteristics of Rice Grains (시비수준(施肥水準) 및 재배지역(栽培地域)이 쌀의 형태적(形態的) 특성(特性)에 미치는 영향(影響))

  • Hong, Young-Pyo;Kim, Seong-Yeol;Im, Jeong-Nam
    • Korean Journal of Soil Science and Fertilizer
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    • v.26 no.2
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    • pp.85-92
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    • 1993
  • This study was investigated on the morphological characteristics of rice grain as affected by three fertilizer application treatments. Of no-nitrogen, optimum nitrogen, and heavy nitrogen without potassium in three regions of Suweon (Mid-West Plain Zone), Ichon(Mid-Inland Plain Zone), and Kyehwado(South-charyung Mts. Plain Zone) with four varieties, i.e., three Tonsil types(Geumgangbyeo, Milyang 23, and Chilseongbyeo) and one japonica type(Chucheongbyeo, Akibare in Japanese name). The results obtained were as follows: The increase of nitrogen application caused an increase of grain length in rough rice and grain width in milled rice, resulting in a decrease of the width/thickness ratio in milled rice. The width and thickness of rice grain produced in Kyehwado were smaller than those in the other regions. Therefore, the ratio of length/width and length/thickness in rice grain produced in Kyehwado was larger. The one thousand grain weight of rice was heavier at the optimum nitrogen level than at the no-nitrogen and heavy nitrogen without potassium treatment levels. The weight percentage of hull in rough rice grain decreased in accordance with the increase of nitrogen application, while the weight percentage of bran in brown rice was constant. This suggested that for the normal development of rice grain a constant ratio of bran is needed. The morphological change of rice grain by fertilizer treatments and the change of region cultivated could not be distinguished from the native characteristics of the variety. Other grain characteristics were discussed in view of treatment and regional effects.

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