• Tuberculosis and Respiratory Diseases
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• v.44 no.1
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• pp.85-92
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• 1997

Background : The standard treatment of recurrent, symptomatic malignant pleural effusion is intrapleural instillation of a chemical agent in an attempt to achieve a sterile inflammation and pleurodesis. There are many drugs used as pleural sclerosing agents, but the efficiency and side effects are different. The present study was undertaken to compare the commonly used drugs, doxycycline and bleomycin. Methods : Thirty-four patients with malignant pleural effusion who needed repeated thoracentesis were randomized to receive treatment with intrapleural instillation of doxycycline or bleomycin Fluid volumes before and after pleurodesis, drainge time, and side effects were analyzed, and the response to treatment was evaluated by clinical examination and chest radiography during admission in the hospital. Also median survival rime were evaluated according to the responses. Results : The response rate was higher in the patients receiving doxycycline than in those receiving bleomycin (87.5% vs 50.0%, p=0.02), and fever, nausea and vomiting were more common in the patients receiving bleomycin. The median survival time was significantly longer in the patients who responded to the sclerotherapy regardless of sclerosing agents. Conclusions : Chemical pleurodesis with doxycycline or bleomycin could reduce or stop pleural effusions and prolong the median survival rimes in these patients. Doxycycline appeared to be more efficient as sclerosing agent than bleomycin in the short-term follow-up periods. But a prospective study with a larger number of patients is warranted.

• Tuberculosis and Respiratory Diseases
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• v.63 no.1
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• pp.24-30
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• 2007

Background: Pleural effusion develops in approximately 40% of pneumonia patients. In 5-10% of these cases, it progresses to complicated parapneumonic effusion (CPPE) or empyema that requires drainage. The prognostic factors of CPPE and empyema remain to be clarified. We examined the treatment outcomes of CPPE and empyema and elucidating their prognostic factors. Methods: One hundred and fifteen patients with CPPE or empyema, who were diagnosed and treated in Kyungpook National University Hospital (Daegu, Korea) between September 2001 and December 2005, were retrospectively analyzed. All the data was acquired from their chart review, and regarding treatment results, the time to defervescence and the length of hospital stay were analyzed. Results: The treatment was successful in 101 patients with a success rate of 87.8%. Multivariate analysis showed the level of pleural fluid lactate dehydrogenase (LDH) to be a significant prognostic factor (odds ratio [OR] 7.37; 95% confidence interval [CI], 1.63 to 33.37; p=0.009). Pussy pleural fluid (r=0.236; p=0.01) and the frequency of urokinase use (r=0.257; p=0.01) correlated with the time to defervescence. However, there was no clinical factor that correlated with the length of hospital stay. Conclusion: The pleural fluid LDH level is a useful prognostic factor for monitoring treatment results of CPPE and empyema.

• Journal of Chest Surgery
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• v.34 no.11
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• pp.879-882
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• 2001

advancement in the treatment of esophageal perforation due to the development of ICU care and antibiotics. There were controversies in the treatment of esophageal perforation when diagnosed after 24hrs. From 1995 to 2000, we performed a buttressed primary repair and mediastinal drainage in 6 Boerhaave\`s syndrome patients among 13 esophageal perforation patients. Two patients died(33%). They died because of pneumonia, ARDS and sepsis on 38th, 39th post-operative day respectively. Two patients had leak at the site of repair which was treated completely with conservative treatment. We report on the result of a buttressed primary repair and mediastinal drainage for 6 Boerhavve\`s syndrome patients.

• Korean Journal of Psychosomatic Medicine
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• v.7 no.1
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• pp.10-25
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• 1999

Children above age of two are able to have sexual excitement, and they actively seek the pleasure actively or passively through touch and masturbation. In late $60_s$ and early $70_s$, Masters, obstetrician, and Johnson, social worker, illustrated four phases of human sexual responses, namely excitement, plateau, orgasmic and resolution phases in both sexes, and multiple orgasms in the female. Their treatment principles of sexual dysfunctions were largely based on behavioral model, introducing the concepts of sensate focus, dual therapy and sex education. Following Masters and Johnson, Kaplan, psychiatrist and psychoanalyst, in the early and mid-$70_s$ introduced new sex therapy which was based on the combination of analytically-oriented psychotherapy and behavior therapy, and classified sexual dysfunctions into three categories such as desire excitement and orgasmic phase disorders. Since $1980_s$ other medical fields joined the stream, putting the concentrated effort on the treatment of the impotence in the male. They have developed penile prosthesis, local injection therapy, and the administration of oral medications. Nowadays Sildenafil(Viagra) seems the best choice for the treatment of the impotence in the male.

• Anxiety and mood
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• v.10 no.2
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• pp.85-94
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• 2014

Non-pharmacological treatments have long been used for paraphilia or sexual offenders, but few clinical studies were conducted. However, recently there were issued cognitive behavioral therapy of paraphilia or sexual offenders based on the research findings obtained so far. In addition, there were the changes of Diagnostic and Statistical Manual of Mental Disorder by American Psychiatric Association at 2014. The methods of cognitive behavioral therapy for paraphilia or sexual offenders were electric aversion therapy, olfactory aversion therapy, ammonia aversion therapy, covert sensitization, masturbatory reconditioning, directed masturbation, verbal satiation, social skill training, assertiveness training etc. By synthesizing the newly reported foreign guidelines for treatment and review articles, the aim of this study is to investigate the non-pharmacologic therapies used for treatment of paraphilia or sexual offenders.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1997.04a
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• pp.115-115
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• 1997

성인에 있어서 급성 후두개염의 발생빈도는 점차 증가하고 있다는 보고들이 있다. 일명 성문상부염(supraglottitis)이라고도 불린다. 이는 비단 후두개뿐만 아니라, 성문상부 구조물의 광범위한 염증을 흔히 동반하기 때문이다. 항생제의 발달로 과거와 같은 심각한 호흡곤란및 급성 상기도 증상을 일으켜, 기관지 절개술 등을 필요로 하는 경우는 많이 줄었다 하더라도 여전히 급성상기도 폐쇄를 일으킬 수 있는 응급질환 중의 하나이다. 저자들은 최근 18년동안 본교실에서 급성 후두개염으로 진단받고 치료받은 성인환자 103례중 77례를 대상으로 후향적으로 임상적 특징, 검사소견, 치료성적 등을 비교, 분석하였다. 문헌고찰과 아울러 보고하고저 한다.

• 대한두경부종양학회:학술대회논문집
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• 1986.11a
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• pp.22.2-24
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• 1986

• 대한두경부종양학회:학술대회논문집
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• 2004.11a
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• pp.257-257
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• 2004

• Tuberculosis and Respiratory Diseases
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• v.47 no.6
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• pp.727-734
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• 1999

본원의 비데오 흉강경술 경험과 문헌에서 볼 때, 흉막강 질환에서 흉강경술의 역활은 수기가 국소 또는 경막하 마취 혹은 전신 마취에서 가능하고 작은 구경의 흉강경으로 전 흉막강을 관찰할 수 있으므로 진단 및 치료 효과가 우수하였다. 흉막강 질환에서의 주요 적응증은 흉수, 농흉, 기흉, 흉막 종양, 흉막의 외상, 흉막강내 이물의 진단 및 치료되고 있다. 흉막강내 각종 수기에 사용하는 기구의 개발과 수기의 발전으로 흉막강내 질환에 대한 치료 성적은 전통적인 개흉수술에 비교하여 우수한 결과를 나타내고 있다.

• 대한두경부종양학회:학술대회논문집
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• 1996.11a
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• pp.251-251
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• 1996