• Journal of agricultural medicine and community health
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• v.31 no.3
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• pp.245-253
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• 2006

Objectives: Since 1983, vaccination for Hepatitis B virus has been recommended for all neonates in Korea. The objectives of this study was to assess the changing trend of the positive rate of HBsAg and anti-HBs in university students in one province. Methods: The study population consisted of one university students who taken physical exam in 2004, which included 8,527 students (3,391 males and 5,136 females). Serum HBsAg and anti-HBs were detected by immunochromatography method. Results: The positivities of HBsAg and anti-HBs were 2.7% and 61.1%. The positivity of HBsAg was significantly higher in males(p< .05), while that of anti-HBs was significantly higher in females(p< .05). There was some differences of HBsAg positivities among age groups. But there was no correlation between age and the positivities. There was some differences of anti-HBs positivities among age groups. But there was no correlation between age and the positivities. Conclusion: The positivity of HBsAg has significantly decreased and that of anti-HBs has increased with years. It was suggested that the changes of positivity were caused by nationwide hepatitis B vaccination program.

• Korea journal of population studies
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• v.32 no.1
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• pp.1-23
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• 2009

This paper uses a survey data to analyze the age-specific fertility rates, age-specific cumulative fertility rates, and ages of marriage of the five birth cohorts of Korean women born in the 1940s and thereafter. It was found that later cohorts reach their highest age-specific fertility rate at higher ages than earlier cohorts. The age-specific cumulative fertility rates of the 1950s and 1960 cohorts were found to be much lower than those of the immediately preceding cohorts, while those of the 1970s and 1980s cohorts were not different from those of the 1960s cohorts. Women belonging to later cohorts were found to get married at relatively higher ages. The estimation results of the hazard model show that women belonging to later cohorts and those with more schooling have a tendency to get married at higher ages. The effect of the birth cohorts is thought to be due to the economic, social, and cultural changes in Korea during the late 50 years or so. The time interval between a woman‘s marriage and first birth was found not to be affected by either the year of marriage or that of her birth. Also, those who remained employed for some time around their marriage and those with low schooling were found to have a lower first child birth hazard, which implies that married women’s employment status and family income play an important role in their decisions on childbirth.

• Journal of the korean academy of Pediatric Dentistry
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• v.49 no.3
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• pp.274-284
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• 2022

The purpose of this study was to analyze the trend of the number of births in Gwangju and the number of outpatients in Pediatric Dentistry at Chonnam National University Dental Hospital over the past 10 years (2010 - 2019) and predict the next year using time series analysis. The number of births showed an unstable downward trend with monthly variations, with the highest in January and the lowest in December. The average number of births in 2020 was predicted to be 682 (595 to 782, 95% CI), and the actual number of births was an average of 610. The number of outpatients was relatively stable, showing a month-to-month variation, with highest in August and the lowest in June. The average number of patients in 2020 was predicted to be 603 (505 to 701, 95% CI), and the average number of actual visits was 587. Despite the decrease in the number of births, the number of outpatients was expected to increase somewhat. Due to the special situation of COVID-19, the actual number of births and patients was to be slightly lower than the predicted values, but it was that they were within the predicted confidence interval. Time series analysis can be used as a basic tool to prepare for the low fertility era in the field of pediatric dentistry.

• Journal of Life Science
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• v.32 no.12
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• pp.1005-1012
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• 2022

This study was conducted to investigate the taxonomic composition and diversity of fecal microbiota between birth and weaning stages of Halla horses using 16S rRNA gene amplicon sequencing analysis. Proteobacteria (35.7%) and Firmicutes (45.6%) were identified as the most common phylum in birth and weaning, respectively. Escherichia (19.7%) and Clostridium (14.0%) were observed as the most dominant genus in birth, and Fibrobacter (6.6%) was the highest in weaning. The results of α-diversity showed that the richness and evenness in microbial communities were statistically significant (p<0.001) in birth and weaning. The results of β-diversity indicated that the birth and weaning stages were clearly divided into two groups at the genus and species levels. Permutational multivariate analysis of variance (PERMANOVA) showed that the microbiota composition differences between birth and weaning were statistically significant (q<0.001). A linear discriminant analysis effect (LEfSe) was performed to select taxonomic makers between the birth and weaning stages. On the genus level, Escherichia, Bacteroides, Clostridium, and Methylobacterium were relatively abundant at birth, whereas Fibrobacter was more abundant at weaning. We expect that this research can be utilized as basic data in the identification of microbial communities involved in disease prevention and nutrient absorption in Halla horses.

• Clinical and Experimental Pediatrics
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• v.46 no.8
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• pp.769-776
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• 2003

Purpose : The survival rate of very low birth weight infants(VLBWI) has improved by virtue of specialized neonatal care. This study was performed to analyze the changes in incidence, survival rate and morbidity of VLBWI who admitted to Chonnam National University Hospital from 1996 to 2001. Methods : We enrolled 565 VLBWI, and compared the incidence and the survival rate according to the birth weight or gestational weeks between period I(1996 to 1998) and period II(1999 to 2001). The mortality rate according to the postnatal age, cause of death, morbidity and days of hospital stay were also compared. Morbidity is categorized into 'short term' which is curable until discharge, and 'long term' causing any types of sequelae after discharge. Results : Incidence of VLBWI significantly increased in period II over period I(6.0% vs. 11.0%, P< 0.001). The survival rate also increased in period II(71.8% vs. 80.1%, P<0.05), especially in 1,000 to 1,249 gm of birth weight(P<0.001) and in 28 to 30 weeks of gestation(P<0.001). The most common cause of death was respiratory distress syndrome in period I; however it was sepsis in period II. Although overall and short term morbidity rate increased, long term morbidity and days of hospital stay didn't increase in period II. Conclusion : Although the incidence of VLBWI significantly increased and the survival improved in period II compared to period I, especially in 1,000 to 1,249 gm of birth weight and 28 to 30 weeks of gestation, 'long term' morbidity rate and hospital days didn't increase.

• Clinical and Experimental Pediatrics
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• v.50 no.8
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• pp.746-752
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• 2007

Purpose : Total hydroperoxide (TH), free radical-mediated oxidation product can be used as a measure of free radical injury. The aim of the present study was to see if preterm newborns are at increased risk for oxidative stress compared with term newborns, and to determine whether oxidative stress during postnatal first 1 week is associated with clinical outcomes in preterm infants. Methods : Serum TH levels of preterm infants (n=39) were compared with those of term infants (n=24) on the postnatal day 1. Among the preterm infants, serum TH levels of uncomplicated group (n=23) were also compared with those of complicated group (n=16) who developed oxygen radical related diseases on the postnatal day 1 and 7. Retrospective analysis was performed to find out risk factors for oxygen radical injuries based on birth history, laboratory data, neuroimaging findings and clinical progress in two preterm groups. Results : Serum TH levels on postnatal day 1 were higher in the preterm infant group than the term infant group. Serum TH levels on postnatal day 1 in the complicated preterm infant group were significantly higher compared with uncomplicated group, but there was no significant difference in serum TH levels on postnatal day 7. Also, there was no significant difference in serum TH levels between uncomplicated preterm infants and term infants. Serum TH level on postnatal day 1 was independently associated with higher morbidity after adjusting for gestational age, Apgar score (5 min), arterial blood gas analysis. Conclusion : Complicated preterm newborns are at increased risk for oxidative stress compared with uncomplicated newborns and term newborns. Oxidative injury during the prenatal or postnatal day 1 is associated with adverse outcomes in preterm infants. Elevated TH levels on postnatal day 1 may have a value to predict clinical outcomes in preterm infants.

• Child Health Nursing Research
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• v.20 no.3
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• pp.185-195
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• 2014

Purpose: The purpose of this study was to identify whether hearing a recording of mother's voice affected physiological reactions, behavioral state related to sleep and weight of very low birth weight (VLBW) infants. Methods: This was a nonequivalent control group pre-post test quasiexperimental design. The participants were 11 VLBW infants in the experimental group and 11 in the control group. In the experimental group, a recording of mother's voice was played to her infant by voice recorder four times each day for five minutes over 10 consecutive days in the incubator. Results: For physiological response (heart rate, respiration rate, oxygen saturation), there were statistically significant differences between the experimental and control groups. Behavioral state during sleep was more very quiet and quiet in the experimental group. In the daily weight change, there was no significant difference between the experimental and control groups. Conclusion: The findings suggest that, for VLBW infants, the intervention of hearing a recording of mother's voice had some significance as a nursing intervention having a positive impact. Such interventions can help pediatric nurses to stabilize the physiological response and maintenance more very quiet sleep state and improve VLBW infants' growth.

• Journal of Nutrition and Health
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• v.44 no.2
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• pp.162-170
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• 2011

We tested the hypothesis that an improved nutritional environment increases the size of stature sexual dimorphism (SSD) by comparing mean height changes in North and South Korean adults. For the first round of sampling, those North Korean refugees who had reached the age of 20 years before leaving North Korea were selected for the study. Then, two birth-year cohorts born between 1955 and 1959 and between 1980 and 1984 were finally selected for the analysis (383 males and 529 females). North Korean refugee mean height data were compared to the mean height of the comparable South Korean population derived from 2004 Korean size results (373 males and 429 females). The results of the analysis showed that there was no increase in mean height among the refugees, either in males or females, between the two birth-year cohorts. As a result, no change in SSD was observed between the two birth-year cohorts. In contrast, South Koreans showed a remarkable increase in height, with males having a greater increase during the corresponding 25 years. Consequently, South Korean SSD increased significantly with time. These results support the hypothesis that improved nutritional quality increases SSD.

• Korean Journal of Agricultural Science
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• v.4 no.2
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• pp.141-145
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• 1977

This study was conducted from 1974 to 1977 at Chedong Animal Farm in Che-Ju to determine the effect of sex of calves, birth year and season, breeds and crossing methods on the birth weight of cattle. A total of 1020 calves from Angus, Charolais, Hereford breeds and their crossbred were used for the study and least square methods was applied to analysis the data. Birth weight of male calves was 1kg heavier than that of female. Highly significant differences were obtained in the effects of birthyear on the birth weight, i.e. the cattle born in 1976 and 1977 was 0.9 and 0.2kg heavier in birth weight than those born in 1975. The cattle born in 1974, when the farm was established, was 1.7kg lighter than those in 1975. The calves born in the spring and the summer was 0.6 and 0.3kg heavier in birth weight than those born in the winter. The calves born in the fall was 0.9kg lighter than the calves born in the winter. In birth weight, Charolais breed were 0.4kg heavier than those from Hereford breed. Angus breed were 1.1kg lighter than Hereford. The crossbred between Charolais and Hereford breed were 1.5kg heavier than the Hereford. The birth weight of calves from Angus and Hereford crossbred and Angus and Charolais crossbred were 0.6 and 0.4kg lighter, than Hereford breed respectively.

• Applied Microscopy
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• v.38 no.3
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• pp.213-219
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• 2008

The plasticity of nervous system is generated not only due to changes in neurons but also due to changes in neuroglial cells. Astrocyte is important for maintaining the normal brain function and controlling the neuronal functions. The amygdala receives an array of important sensory information of danger signals. This information is further transduced and integrated to produce the highly adaptive emotion, fear. In this study, morphometric changes in the cell bodies of astrocytes in the amygdala, induced by prenatal stress and restraint stress were examined. For this purpose. rats were classified into 4 groups; control group (CON), only restraint-stressed (starting on P90 for 3 days) group (CONR), prenatally-stressed group (PNS), and prenatally and restraint (on P90 for 3 days) stressed group (PNSR). Astrocytes were verified with anti-GFAP immunohistochemistry, counter stained with methylene blue/azure II and were examined using the Neurolucida. Results showed that astrocytes in the amygdala of PNS rats had significantly larger cell bodies than did CON rats and this was enhanced further by restraint stress. Thus this data showed that hypertrophy of the astrocytic cell bodies of amygdala complex is induced by prenatal and restraint stress.