• Development and Reproduction
• /
• v.16 no.2
• /
• pp.121-128
• /
• 2012

Kisspeptin has been reported to facilitate sexual maturation and ovulation by directly stimulating GnRH neurons via its receptor, GPR54. The KiSS-GPR54 system is playing an important role in the reproduction of several mammalian species. However, little is known about their function in fish. The aim of this study is to understand the physiological function and evolutionary conservation of KiSS-GPR54 system in teleost fish blacktip grouper, Epinephelus fasciatus. In the present study, we have partial cloned KiSS1, KiSS2 GPR54 mRNAs from a brain samples. Tissue distribution analysis using RT-PCR revealed that the KiSS1, KiSS2, GPR54 transcripts were expressed in different tissue. The KiSS-GPR54 system in gonadal of immature and mature stage were analyzed using qRT-PCR. The partial sequence of KiSS1, KiSS2, GPR54 were 232 bp, 304 bp, 613 bp long, respectively. KiSS1, KiSS2, GPR54 mRNAs are shown common expression in the brain. The amount of KiSS1, KiSS2 mRNAs expression were significantly higher in mature stage than immature stage. However GPR54 mRNA expression was higher in immature stage. These results are in good agreement with the hypothesis that KiSS-GPR54 system plays an important role in the regulation of reproductive function in the blacktip grouper.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.17 no.1
• /
• pp.72-78
• /
• 2016

This study examined the oral health-related quality of life of the elderly using the oral health index and dental prosthesis status, and explored methods to improve the oral health status. The data collected from 'The fifth Korean national health and nutrition examination survey 2010' were analyzed. The subjects were 2273 elderly people, aged 65 years or older, who had completed an oral examination, health questionnaires and nutrition examination. Statistical analysis was done using the SPSS 22.0 for Windows. Frequency analysis, multiple regression analysis and structural equation model were used for statistical analysis. The general characteristics, oral health index and dental prosthesis showed differences in the subjective oral health status associated with as age, ST, FS-T, T-Health, maxillary crown needs, maxillary denture needs, mandibular denture needs, chewing status associated with the income level, FS-T, maxillary crown needs, maxillary denture needs, mandibular denture needs, speaking status associated with the ST, T-Health, maxillary implant status, and maxillary denture needs. In conclusion, both the oral health index and dental prosthesis needs affect the oral health related quality of life of the elderly. Governments should implement a variety of oral health programs and dental prosthesis policies to improve the quality of life related oral health of the elderly.

• Korean Journal of Social Welfare Studies
• /
• v.43 no.1
• /
• pp.117-142
• /
• 2012

This research attempts to explain the influence of educational level inequalities on self-rated health and depression of the elderly. Also, we are focusing whether there is a mediating effect of social support between educational level inequalities and self-rated health depression of the elderly. The data was collected from July, 30 to August, 15, 2009. 631 persons who live in Gangnam-Gu area over 60 years of age were recruited. Frequency, percentage, mean, standard deviation and multiple regression were employed using SPSS 12.0. The result of this study shows that educational level inequalities have a influence on the self-rated health and depression. It is also verified that social participation variable has a partial mediating effect between educational level inequalities and mental health(self-rated health and depression). This study carried out a positive linear relationship between educational level and health: the higher education, the better the health. And also, the results present the importance of developing adequate intervention programs for the elderly having low educational level to improve social participation and to enhance mental health(self-rated health and depression).

• Journal of the Health Care and Life Science
• /
• v.8 no.2
• /
• pp.155-163
• /
• 2020

The purpose of this study is to examine the current status of the Injury based on the 7th National Data on the National Health and Nutrition Survey, identify the relationship between general characteristics, safety awareness, health status, injury, and identify the factors that affect the occurrence of injury. The subjects were selected for the final analysis of 1,608data. For the analysis, frequency analysis, cross analysis, and multiple logistic regression analysis were performed. the results of the study show that in the young-old elderly, gender(woman), marital status(separated of divorced), lower the awareness of safety, body discomfort, sickness, and in-outpatient, Annual unmet medical service experienced are higher the occurrence of injury. Therefore, as a prevention education that lowers the incidence of injury. selective education is required for the Young-old and Old-old elderly, and legal penalties for drunk driving on various means of transportation and an integrated approach to strengthening and education is required.

• Journal of Korean Home Economics Education Association
• /
• v.19 no.3
• /
• pp.61-76
• /
• 2007

The purpose of the study is to identify and understand problems existing in the middle school home economics practice rooms in Jeju Special Self-Governing Province. The findings are based on the examination and the analysis of the indoor environment and the condition of the facilities and equipment. Study method employs on-site research and a survey. The on-site research was conducted about temperature, humidity, intensity of illumination, and status of teaching instrument in 10 out of 41 middle schools in Jeju Special Self-Governing Province from August 16 to September 30, 2006. Meanwhile, the survey was implemented by mail for 95 teachers in charge of manual training and home economics education in 41 middle schools in Jeju from November 1 to 23, 2005. 64 questionnaires out of total 95 were collected, including those collected during the period of on-site research. Finally, 61 questionnaires which were effective among the answered ones were used for analysis. Collected materials were analyzed with the SPSS Win.12.0 program for frequency, percentile analysis. In conclusion, the study determines that the condition of the home economics practice rooms of the middle school in JSSGP in terms of temperature, humidity, lighting and ventilation is very inadequate. The structure of the practice room represents an inefficient work flow pattern. Further, the facilities and equipment are in a very poor condition because the facilities are old and the retention rate of teaching tools is low. Therefore, to address these problems, the study suggests that improvements on the facilities and equipment should be made and teaching tools should be replenished in accordance with the industry standard.

• Journal of Oral Medicine and Pain
• /
• v.34 no.1
• /
• pp.1-9
• /
• 2009

Liver transplantation is definitive treatment for the patients suffering from hepatitis, severe liver cirrhosis and liver cancer. In these patients, systemic infections under immunosuppression may occur easily. Therefore, primary object of dental treatments before liver transplantation is absolute removal of oral infection source. In addition, comprehensive dental management plan is essential for success of liver transplantation. The present study has been performed to investigate decayed, missing and filled permanent teeth index(DMFT index), degree of oral hygiene, past medical history, need of dental treatment, completion of dental treatment need and time interval between dental visit and operation date of liver transplantation in liver transplant candidates. Obtained results were as follows; 1. Decayed teeth of the patients were 2.68, missing teeth were 4.02 and filled teeth were 3.42. DMFT index was 10.12. 2. Twenty percents of patients showed moderate to severe food impactions, 42.2% of patients had moderate to heavy calculus and 37.8% of patients displayed gingival inflammation with swelling. 3. Patients needed periodontal treatments more than any other dental treatments. Periodontal treatments were needed for 88.9% of patients, operative & endodontic treatments were 46.7% of patients and 33.3% of patients needed for oral & maxillofacial surgical treatments. 4. Among 90 patients, time interval between scheduled operation date of liver transplantation and dental visit was within 2 weeks for 32.2% of patients, within 1 week for 20.0% of patients. In conclusion, most liver transplant candidates needed dental treatments for removal of potential infection sources. However because of insufficient interval between dental visit and operation date, they had taken liver transplantation procedures without comprehensive dental management. Development of preventive and comprehensive dental management program is mandatory for these patients. Cooperative interdisciplinary management will play a positive role for successful liver transplantation.

• Journal of Ginseng Research
• /
• v.24 no.4
• /
• pp.176-182
• /
• 2000

The effects of red ginseng component (water extracts, alcohol extracts, lipophilic extracts, total saponins, panaxadiol and panaxatriol) administration on glutathione (GSH) and lipid peroxidation levels in mice were investigated. 20~25 g ICR mice which were pretreated with water extracts (50 mg/kg), alcohol extracts (50 mg/kg), lipophilic extracts (50 mg/kg), total saponins (50 mg/kg), panaxadiol (50 mg/kg) and panaxatriol (50 mg/kg) for 15 days. The ability of red ginseng component to protect against oxidative damage to the mouse liver was examined by determining the level of lipid peroxidation (MDA), glutathione, and the activities of glutathione peroxidase (GPX). The GSH level was raised by all the ginseng component, but the GSSG level was lowered ]argely by all the ginseng component. The ratio of GSSG/total GSH was decreased because the level of GSSG was decreased more than that of GSH. Finally, the lipid peroxidation (MDA) level was the lowest in lipophilic extracts and panaxadiol nest. In conclusion, the order of effectiveness of anti-oxidants was to be lipophilic extracts>panaxadiol>total saponins.

• Microbiology and Biotechnology Letters
• /
• v.27 no.6
• /
• pp.427-432
• /
• 1999

For the development of a multifunctional biocontrol agent, the siderophore-producing strain GL7 was isolated from a rhizosphere on chrome azurol S agar. The GL7 was identified as a strain of Pseudomonas fluorescents on the basis of their reactions to standard physicochemcial tests from Bergey's manual, API diagnostic test, and fatty acid analysis. P. fluorescents GL7 considerably inhibited spore germination and hyphal growth of phytopathogenic fungus Funsarium solani in a dual culture. In pot trials of bean with P. fluorescens GL7, the disease incidence was significantly reduced down to 5% from 70% of incidence in the untreated control. P. fluorescens GL7 also enhanced plant growth to nearly 1.5 times than that of the untreated control, promoting elongation and development of the roots. These results suggest that the plant growth-promoting P. fluorescens GL7 can play an important role in the biological control of soil-borne plant disease in a rhizosphere.

• Health Policy and Management
• /
• v.34 no.3
• /
• pp.293-308
• /
• 2024

Background: Assessing the change in mental health status of quarantined patients in community treatment centers at the time of admission and discharge, and inferring the influencing factors. Methods: The study was conducted on a sample of 1,941 quarantined patients from three community treatment centers. Changes in anxiety, psychological distress, post-traumatic stress, depression, and self-harm ideation between admission and discharge were categorized as either "improved" or "worsened." Inference was performed to determine the probability of worsening in mental health status. Results: The mental health status of quarantined patients, such as anxiety and depression, was relatively higher than that of the general population. Anxiety (84.3% improved) and psychological distress (79.0% improved) were reduced during quarantine treatment. However, some patients continued to experience moderate to severe levels of anxiety (11.2%) and psychological distress (11.0%) at discharge. As for depression, the depression of moderate or higher level was increased at the time of discharge (28.7%→36.7%) compared to admission. The deterioration of anxiety and psychological distress was found to be the most significant factor influencing the worsening of depression at discharge (odds ratio [OR] for anxiety deterioration, 2.04; OR for psychological distress deterioration, 3.56). These effects were also observed similarly in post-traumatic stress and self-injury ideation. Conclusion: Improving anxiety and psychological distress among quarantined patients in community treatment centers can reduce the worsening of post-traumatic stress, depression, and self-injury ideation at the time of discharge. These findings provide evidence for the need for active mental health management from the initial stages of quarantine treatment.

• Korean journal of applied entomology
• /
• v.57 no.1
• /
• pp.33-38
• /
• 2018

Walnuts are one of the most economically important fruit trees in forestry. In walnut orchards, however, studies examining damage by insect pests are limited. This study was conducted to investigate the rate of damage caused by Conogethes punctiferalis to walnut fruits and by Acrocercops transecta to walnut leaves. In 2017, the change of damage rate (caused by C. punctiferalis) to fruits were investigated in Buyeo. In addition, we counted fruits and leaves damaged by two lepidopteran species in Gimcheon, Buyeo, Yeongdong, and Hwaseong. Damaged fruits steadily increased in abundance with fruit growth in Buyeo, and the highest number of damaged fruits was documented in late summer. The rates of damage caused by C. punctiferalis to fruits in Buyeo, Gimcheon, and Hwaseong were 22.1%, 20.5%, and 11.7%, respectively. Additionally, the rates of damage caused by A. transecta to leaves in seedlings (58.5% on average) were significantly higher than to those in older trees (11.2% on average), irrespective of the study location. In conclusion, this study showed that C. punctiferalis and A. transecta were serious pests affecting walnut fruits and leaves, respectively. Therefore, management methods for these insect pests need to be developed.