• Clinical and Experimental Reproductive Medicine
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• v.34 no.2
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• pp.95-106
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• 2007

Objective: We previously identified differentially expressed genes (DEGs) between germinal vesicle (GV) and metaphase II (MII) mouse oocyte. The present study was accomplished as a preliminary study to elucidate the role of ribose 5-phosphate isomerase A (Rpia), the essential enzyme of the pentose phosphate pathway (PPP), in oocyte maturation. We observed expression of Rpia in the mouse and porcine oocytes. Methods: Expression pattern of the 11 MII-selective DEGs in various tissues was evaluated using RT-PCR and selected 4 genes highly expressed in the ovary. According to the oocyte-selective expression profile, we selected Rpia as a target for this study. We identified the porcine Rpia sequence using EST clustering technique, since it is not yet registered in public databases. Results: The extended porcine Rpia nucleotide sequence was submitted and registered to GenBank (accession number EF213106). We prepared primers for porcine Rpia according to this sequence. In contrast to the oocyte-specific expression in the mouse, Rpia was expressed in porcine cumulus and granulosa cells as well as in oocytes. Conclusion: This is the first report on the characterization of the Rpia gene in the mouse and porcine ovarian cells. Results of the present study suggest that the mouse and porcine COCs employ different mechanism of glucose metabolism. Therefore, the different metabolic pathways during in vitro oocyte maturation (IVM) in different species may lead different maturation rates. It is required to study further regarding the role of Rpia in glucose metabolism of oocytes and follicular cell fore exploring the regulatory mechanism of oocyte maturation as well as for finding the finest culture conditions for in vitro maturation.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.13 no.2
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• pp.115-123
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• 2018

This study is empirically intended to put forward the modeling and process improvement measures for the SCM capability in small venture firms. The findings are summarized as follows. There were strategic alliance, technological development and centralization in the modeling of strategic planning for supply chain, not the least of which is strategic alliance, followed by centralization and technological development. There were routing scheduling, network integration and third party logistics outsourcing in decision making, not the least of which was network integration. There were customer service management, productivity management and quality management in management control, not the least of which was quality management. And there were order management choice, pricing demand, shipment delivery and customer management in transaction support system, not the least of which was order management choice. As for the above-mentioned findings, to maximize the SCM capability and operate the optimized process in small venture firms, the existing strategic alliances can optimize the quality management and stabilize the transaction support system through the network sharing and integration from the perspective of relevant organizational members' capability and process improvement. And the strategic linkage between firms can maximize the integrated capability of information system beyond the simple exchange relation between electronic data, achieving a differentiated competitive advantage. Consequently, the systematization and centralization for the maximization of SCM capability, including the infrastructure construction based on the system compatibility and reliability for information integration, should be preceded before the modeling of the integrated capability for optimum supply chain and the best process management in the smart era.

• Journal of Korean Society of Transportation
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• v.10 no.1
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• pp.55-62
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• 1992

교통수요는 교통정책 및 교통시설 계획의 수립 및 평가에 중요한 영향을 미치게 되므로 교통수요의 예측은 교통연구에서 중요한 부문을 차지하고 있다. 도로밑에 설치된 전자차량감지기(Electronic Vehicle Detector)로부터 자동 수집된 링크 교통량 자료(Traffic Counts)를 주요 입력자료로 이용하여 계획지역의 기종점 통행표(Origin Destination Trip Matrix)를 작성할 수 있는 기법 들이 최근 수년동안 많이 발달하게 되었다. 이러한 새로운 기법들은 가구조사(Home Inteview), 노변면접조사(Road-Side Interview)등을 토하여 조사된 자료를 기초로하는 전통적은 4단계 교통수요추정방법(Conventional 4-Stage Estimation Method)-통행발생(Generation), 통행분포(Distribution), 수단선택(Modal Split), 교통배분(Assignment)-과 비교하여 첫째로 정확도가 높은 링크 교통량 자료를 별도의 조사를 거치지 않고서도 수집이 가능하기 때문에 조사비용이 거의 들지 않아도 되어 경제적이고, 둘째로 전통적인 수요예측방법들에서 요구되어지는 복잡한 모형수립 및 계수조정(Parameter Calibration)이 필요하지 않아 간편하고 셋째로 오래전에 작성된 기종점 통행표를 단순히 링크 교통량 자료만을 이용하여 쉽게 보완할 수 있어 지속적인 자료의 축적(Data Age-ing)이 가능하며 더 나아 가서 소위 연속적인 교통 계획 및 교통시설관리(Continuous Transport Planning and Management)를 가능케 하는 등의 여러 장점 때문에 많은 주목을 받아 오고 최근 몇 년이 꾸준히 실무에 유용하게 적용이 되고 있는 실정이다. 본 연구는 링크 교통량자료를 이용하여 기종점 통행표를 작성하기 위하여 개발된 기존의 여러 기법들 가운데 특히 용량제약조건(Capacity-Restrained Condition)하에서 기존의 방법들을 상호 검토한 후 Wardrop의 교통망 평형원칙(Wardrop's First Network Equilibrium Principle)을 만족하는 새로운 추정기법을 제의하고 이의 시험결과를 논의하는 것을 주요내용으로 한다. 링크 교통량 자료를 이용하여 기종점 통행표를 작성하는 기법들의 근본 목표는 조사된 링크 교통량(Ob-served Traffic Counts)에 가장 근접한 교통망 통행 배정 링크 교통량(Assigned Link Volumes)을 재현(Re-producing)할 수 있는 기종점 통행표들 중에서 최적의 기종점 통행표를 발견하는 것이다. 따라서 교통망에서 통행자의 여행 경로 배정을 가장 잘 반영할 수 있는 현실적인(Realistic) 교통망 통행 배정 모형(Net-work Traffic Assignment Model)의 선택은 중요한 요소가 되며 특히 교통망에 교통체증(Traffic Conges-tion)이 심할 경우 교통망 통행자 평형조건(Network Traffic Equilibrium Condition)을 고려하기 위한 특별한 처리가 요구되어진다. 본 연구는 Whllumsen(Hall, Van Vliet and Willumsen, 1980)에 의하여 개발된 ME2(Maximum Entropy Matrix Estimation)기법에서 반복식 추정방법(Sequential Estimation Method)을 사용할 경우 Wardrop의 평형조건을 만족하는 기종점 통행표를 구할 수 없다는 단점을 극복하기 위한 방안으로서 엔트로피 극대화문제와 교통망 평형 조건(Entropy Maximisation and Network Equilibrium Condition)의 두 문제를 동시에 해결할 수 있는 새로운 수식모형과 이를 풀기 위한 알고리즘(Simultaneous Solution Algorithm)을 제의하였다. 제의된 수식모형과 알고리즘을 예제 교통망(Example Network)을 이용한 시험하고 그 결과를 ME2 의 반복식 추정 방법으로부터 구한 기종점 통행표와 비교 검토하였다.

• Smart Media Journal
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• v.10 no.2
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• pp.61-69
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• 2021

Wayfinding is a 'Process solving problem to find destination', and it is important to select spatial data for optimal way. Recently, due to the complexity of space and the expansion of the medium of the wayfinding service, it is necessary to the approach on the information design for them. Therefore, the purpose of this study is to propose a meta guideline on the information design for the design of orientation sign, which is an important cognitive clue in the wayfinding. It was conducted in 3 stages, First, a design process was proposed and design elements were derived for each step by literature research related to information and sign design, and analysis of manual for signage design. Second, a meta guideline for information organization and visualization in the three-stage design process was proposed by FGI and analysis. Third, the meta guideline was applied to the sign design on an area for user evaluation to inspect the applicability of the meta guideline. Through the user questionnaire, the possibility of applying the guideline for visualization of directions and spaces, information hierarchy according to spatial characteristics and information priority was identified. It is meaningful in that necessary element for signage design are systematized centering on the process and that it presents a macroscopic methodology according to spatial characteristics.

• Journal of the Korean Academy of Esthetic Dentistry
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• v.30 no.2
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• pp.71-90
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• 2021

The virtual patient dataset is a collection of diagnostic data from various sources acquired from a single patient into a coordinate system of three-dimensional visualization. Virtual patient dataset makes it possible to establish a treatment plan, simulate various treatment procedures, and create a treatment planning delivery device. Clinicians can design and simulate a patient's smile on the virtual patient dataset and select the optimal result from the diagnostic process. The selected treatment plan can be delivered identically to the patient using manufacturing techniques such as 3D printing, milling, and injection molding. The delivery of this treatment plan can be linked to the final prosthesis through mockup confirmation through provisional restoration fabrication and delivery in the patient's mouth. In this way, if the diagnostic data superimposition and processing accuracy during the manufacturing process are guaranteed, 3D digital smile design simulated in 3D visualization can be accurately delivered to the real patient. As a clinical application method of the virtual patient dataset, we suggest a decision-making method that can exclude occlusal adjustment treatment from the treatment plan through the digital occlusal pressure analysis. A comparative analysis of whole-body scans before and after temporomandibular joint treatment was suggested for adolescent idiopathic scoliosis patients with temporomandibular joint disease. Occlusal plane and smile aesthetic analysis based on the virtual patient dataset was presented when treating patients with complete dentures.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.43 no.3 s.345
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• pp.39-48
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• 2006

In this paper, we analyze the spectral efficiency of multicarrier-code division multiple access (MC-CDMA) scheme. First, we derive a generalized formula for the spectral efficiency according to the number of subcarriers involved in, code division multiplexing and the number of codes used (i.e., loading factor), under a given set of channel coefficients. Also, we derive a generalized formula for spectral efficiency of various reduced-complexity systems that divide the full sets of subcarriers into several groups of subcarriers for code division multiplexing. Then, through these derivations, we establish an inter-relationship between the frequency selectivity and diversity order according to the number of multipaths. From the results, we choose the smallest code length while maximizing the diversity effect, provide an optimum subcarrier allocation strategy, and finally suggest a system structure for capacity-maximizing under the smallest code length. Through numerical analyses under simulated environments, we analyze the properties of spectral efficiency of various systems with reduced complexity and choose a major contributing factors to system design and a better system design methodology. Finally, we compare the spectral efficiency of the MC-CDMA scheme and orthogonal frequency division multiplexing (OFDM) scheme to make a relationship between both schemes.

• Journal of KIISE:Computing Practices and Letters
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• v.11 no.1
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• pp.15-25
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• 2005

Embedded systems have a set of tasks to execute. These tasks can be implemented either on application specific hardware or as software running on a specific processor. The design of an embedded system involves the selection of hardware software resources, Partition of tasks into hardware and software, and performance evaluation. An accurate estimation of execution time for extreme cases (best and worst case) is important for hardware/software codesign. A tighter estimation of the execution time bound nay allow the use of a slower processor to execute the code and may help lower the system cost. In this paper, we consider an ARM-based embedded system and developed a tool to estimate the tight boundary of execution time of a task with loop bounds and any additional program path information. The tool we developed is based on an exiting timing analysis tool named 'Cinderella' which currently supports i960 and m68k architectures. We add a module to handle ARM ELF object file, which extracts control flow and debugging information, and a module to handle ARM instruction set so that the new tool can support ARM processor. We validate the tool by comparing the estimated bound of execution time with the run-time execution time measured by ARMulator for a selected bechmark programs.

• Journal of the Korean Society for information Management
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• v.39 no.2
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• pp.233-254
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• 2022

Link reduction algorithms such as pathfinder network are the widely used methods to overcome problems with the visualization of weighted networks for knowledge domain analysis. This study proposed NetRSQ, an indicator to measure the goodness of fit of a link reduction algorithm for the network visualization. NetRSQ is developed to calculate the fitness of a network based on the rank correlation between the path length and the degree of association between entities. The validity of NetRSQ was investigated with data from previous research which qualitatively evaluated several network generation algorithms. As the primary test result, the higher degree of NetRSQ appeared in the network with better intellectual structures in the quality evaluation of networks built by various methods. The performance of 4 link reduction algorithms was tested in 40 datasets from various domains and compared with NetRSQ. The test shows that there is no specific link reduction algorithm that performs better over others in all cases. Therefore, the NetRSQ can be a useful tool as a basis of reliability to select the most fitting algorithm for the network visualization of intellectual structures.

• Korean Journal of Agricultural and Forest Meteorology
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• v.25 no.4
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• pp.284-301
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• 2023

The changes in rice climatic yield potential (CYP) across the Korean Peninsula are evaluated based on the new climate change scenario produced by the National Institute of Agricultural Sciences with 18 ensemble members at 1 km resolution under a Shared Socioeconomic Pathway (SSP) and Representative Concentration Pathways (RCP) emission scenarios. To overcome the data availability, we utilize solar radiation f or CYP instead of sunshine duration which is relatively uncommon in the climate prediction f ield. The result show that maximum CYP(CYPmax) decreased, and the optimal heading date is progressively delayed under warmer temperature conditions compared to the current climate. This trend is particularly pronounced in the SSP5-85 scenario, indicating faster warming, except for the northeastern mountainous regions of North Korea. This shows the benef its of lower emission scenarios and pursuing more efforts to limit greenhouse gas emissions. On the other hand, the CYPmax shows a wide range of feasible futures, which shows inherent uncertainties in f uture climate projections and the risks when analyzing a single model or a small number of model results, highlighting the importance of the ensemble approach. The f indings of this study on changes in rice productivity and uncertainties in temperature and solar radiation during the 21st century, based on climate change scenarios, hold value as f undamental information for climate change adaptation efforts.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.16 no.2
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• pp.51-78
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• 2021

Followed by 'start-up', the theme of 'scale-up' has been considered as an important agenda in both corporate and policy spheres. In particular, although it is a term commonly used in industry and policy fields, even a conceptual definition has not been achieved from the academic perspective. "Corporate Growth" in the academic aspect and "Business Growth" in the practical management field have different understandings (Achtenhagen et al., 2010). Previous research on corporate growth has not departed from Penrose(1959)'s "Firm as a bundle of resources" and "the role of managers". Based on the theory and background of economics, existing research has mainly examined factors that contribute to firms' growth and their growth patterns. Comparatively, we lack knowledge on the firms' growth with a focus on 'annual revenue growth rate'. In the early stage of the firms, they tend to exhibit a high growth rate as it started with a lower level of annual revenue. However, when the firms reach annual revenue of more than 100 billion KRW, a threshold to be classified as a 'middle-standing enterprise' by Korean standards, they are unlikely to reach a high level of revenue growth rate. In our study, we used our sample of 333 companies (6.7% out of 5,000 'fastest-growing' companies) which reached 15% of the compound annual growth rate in the last three years with more than USD 100 million. It shows that sustaining 'high-growth' above a certain firm size is difficult. The study focuses on firms with annual revenue of more than $100 billion (approximately 120 billion KRW) from the 'Inc. 2020 fast-growing companies 5,000' list. The companies have been categorized into 1) Fast-growing companies (revenue CAGR 15%~40% between 2016 and 2019), 2) Hyper-growing companies (40%~99.9%), and 3) Super-growing (100% or more) with in-depth analysis of each group's characteristics. Also, the relationship between the revenue growth rate, individual company's strategy choice (market orientation, generic strategy, growth strategy, pioneer strategy), industry/market environment, and firm age is investigated with a quantitative approach. Through conducting the study, it aims to provide a reference to the 'Hyper-Growing Model' that combines the paths and factors of growth strategies. For policymakers, our study intends to provide a reference to which factors or environmental variables should be considered for 'optimal effective combinations' to promote firms' growth.