• Title/Summary/Keyword: 초기 유효선량

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Correlation of Effective Dose and BMI in Radioiodine($^{131}I$) Therapy (방사성옥소($^{131}I$) 치료 시 유효선량과 체질량지수의 상관관계)

  • Shin, Gyoo-Seul;Kim, Gun-Jae;Dong, Kyung-Rae;Kim, Hyun-Soo
    • Journal of radiological science and technology
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    • v.31 no.1
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    • pp.11-16
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    • 2008
  • Purpose : The aim of this study was to predict radiation dose at 1 meter with BMI(body mass index) in thyroid cancer patients treated with radio-iodine and provide the efficient guideline in the management of patients. Methods : 140 patients from thyroidectomy for thyroid cancer were enrolled. All subjects under went 150 mCi radio-iodine therapy and performed whole body scan 1 week later. BMI(weight divided by square of height) was calculated to evaluate the amount of fatty tissue indirectly. The radiation dose at 1 meter was measured initially and on 2nd days. the relation of values with BMI were analyzed statically. As for the method of statistical analysis, using Med calc Version 9,2,2,0 Program. Results : (1) The initial effective dose was inversely correlated with the BMI. Significance level was 0.0004. (2) We obtained the following formula from the data of initial effective dose and BMI: Y = -30.91X + 350.4(${\mu}Sv/h$)(Y: initial radiation dose, x: Group). (3) After 21.55 hours, than radiation dose was less than those recommended by ICRP or NRC in 53% of the population. Conclusion : Using BMI, the initial radiation dose and 2nd days dose can be predicted in thyroid cancer patients before radio-iodine therapy. It may be used for predicting the time of discharge and control the isolation room. We were able to predict the radiation exposure after discharge using this calculated value.

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Interpretation of Uranium Bioassay Results with the ICRP Respiratory Track and Biokinetic Model (ICRP 호흡기 및 생체역동학적 모델을 이용한 우라늄 생물분석 결과의 해석)

  • Kim, H.K.;Lee, J.K.
    • Journal of Radiation Protection and Research
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    • v.28 no.1
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    • pp.43-50
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    • 2003
  • This study describes a practical method for interpretation of bioassay results of inhaled uranium to assess the committed effective doses both for chronic and acute intake situations. Organs in the body were represented by a series of mathematical compartments for analysis of the behavior of uranium in the body according to the gastrointestinal track model, respiratory track model and biokinetic model recommended by the ICRP. An analytical solutions of the system of balance equations among the compartments were obtained using the Birchall's algorithm, and the urinary excretion function and the lung retention function of uranium were obtained. An initial or total intakes by intake modes were calculated by applying excretion and retention functions to the urinary uranium concentration and the lung burden measured with a lung counter. The dose coefficients given in ICRP 78 are used to estimate the committed effective doses from the calculated intakes.

Analysis of Dose by Items According to Act on Safety Control of Radiation Around Living Environment (생활주변방사선안전관리법 시행에 따른 항목별 선량 분석)

  • Jeong, Cheonsoo;Oh, Hyunji;Lee, Jieun;Jo, Sumin;Park, Sohyun
    • Journal of the Korean Society of Radiology
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    • v.7 no.6
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    • pp.377-381
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    • 2013
  • The study attempted to analyze items presented in Act on safety control of radioactive rays around living environment, which has been recently enacted. The test items have been divided into cosmic rays, cosmic rays, terrestrial radiation, and byproduct, etc., and the selected locations for measurement included an airplane at 8000m in the air, mountainous area at 1000m above sea level, 15m-underground building, construction site, and seashore at 0m altitude. The test showed that, based on cosmic rays, plane at 8000m in the air had 4.91mSv/y of effective dose per year. The mountainous area at 1000m above sea level, which was chosen to measure cosmic rays and terrestrial radiation, was measured 0.35mSv higher than the seashore at 0m in altitude due to the effect of cosmic rays and terrestrial radiation from the greater height above sea level. The construction site, chosen as a location to measure byproduct, showed the highest value among the items with 6.66mSv, which is as 10times high as that of a completed building. The seashore at 0m in altitude had 5.96mSv, and, 15m-underground building, based on terrestrial radiation, was the lowest with 4.91mSv. This suggests that, despite the assumption that terrestrial radiation will have greater effect deeper underground, it did not affect inside the building significantly. This study showed that the items presented in Act on safety control of radioactive rays around living environment were not close to effective dose limit for radiation workers proposed by ICRP. However, they were between 4 and 7 times higher than that for general public. This suggests that there should be continuous research on and attention to Safe Management of Daily Surrounding Radiation Act, which is still at its beginning stage.

Experiment of Flexural Behavior of Prestressed Concrete Beams with External Tendons according to Tendon Area and Tendon Force (강선량 및 긴장력에 따른 외부 강선을 가진 PSC 보의 휨거동 실험)

  • Yoo, Sung-Won;Yang, In-Hwan;Suh, Jeong-In
    • Journal of the Korea Concrete Institute
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    • v.21 no.4
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    • pp.513-521
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    • 2009
  • Recently, the externally prestressed unbonded concrete structures are increasingly being built. The mechanical behavior of prestressed concrete beams with external unbonded tendon is different from that of normal bonded PSC beams in that the slip of tendons at deviators and the change of tendon eccentricity occurs as external loads are applied in external unbonded PSC beams. The purpose of the present paper is therefore to evaluate the flexural behavior by performing static flexural test according to tendon area and tendon force. From experimental results, before flexural cracking, there was no difference between external members and bonded members. However, after cracking, yielding load of reinforcement, ultimate load, and the tendon stress of external members was lower than that of bonded members. For the relationship of load-tendon stress, the increasing of tendon strain was inversely proportional to the initial tendon force. However, even if the initial tendon force was large, the tendon strain with small effective stress was smaller than that with large effective stress. The concrete compressive strain was proportional to the effective stress of external tendon. From the comparison between test results and codes, the ACI-318 could not consider the effect of tendon force or effective stress, and especially the results of ACI-318 were very small, so it was very conservative. And the AASHTO 1994 could be influenced on the tendon area, initial force and effective stress, but as it was made on the basis of internal unbonded tendon, its results were much larger than the test results. For this reason, the new correct predict equation of external tendon stress will be needed.

Measurement of Effective Half-life Using Dual Time I-131 Whole Body Scan in Patients with Differentiated Thyroid Cancer Treated by High Dose Therapy (고용량 방사성옥소 치료를 받은 갑상선분화암 환자에서 Dual Time I-131 Whole Body Scan을 이용한 유효반감기의 측정)

  • Yoon, Jae Sik;Lee, Jae Gon;Lee, Ki Hyun;Lim, Kwang Seok;Choi, Hak Ki;Lee, Sang Mi
    • The Korean Journal of Nuclear Medicine Technology
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    • v.18 no.1
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    • pp.98-103
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    • 2014
  • Purpose: The effective half life of I-131 is useful to calculate radiation dose, period of hospitalization, and exposure dose of surrounding people from patient. However, it is difficult to measure. This study estimates the effective half life in whole body and thyroid in using of value of residual radioactivity obtained from the early and delay images of Dual time I-131 whole body scan. Also, the correlations between the effective half life and serum creatinine, GFR, and administration dose were investigated in this study. Materials and Methods: The targets were 50 patients administration high dose of I-131 from February to August in 2013, having normal range of serum creatinine and over $30{\mu}IU/mL$ of TSH levels. After administration radioactive I-131, the early scan in the 3rd day and the delay scan in the 5-6th days were performed. To measure the residual radioactivity in the whole body and thyroid, ROI was set and then background radioactivity was corrected to estimate. The effective half life was estimated by calculating the ratio of measured values between the early and delay images. To compare the effective half lives of the whole body and thyroid, it was analyzed by Independent t-test, and each correlation of the effective half life, GFR, serum creatinine, and the dose of administration were analyzed by calculating the pearson's correlation coefficient. All of the analysis were determined to be statistically significant when P<0.05. Results: The effective half life of the whole body was $17.06{\pm}5.50$ hours and of the thyroid was $17.22{\pm}5.41$ hours. The two effective half life did not show significant difference (P=0.887). As the value of GFR was increased, the effective half life of whole body (r=-0.407, P=0.003) and of thyroid (r=-0.473, P=0.001) were significantly decreased; as the value of serum creatinine was increased, the effective half life of whole body (r=0.309, P=0.029) and of thyroid (r=0.371, P=0.008) were significantly increased. In the administration dose, effective half life did not have correlations. Conclusion: The effective half life of I-131 of patients treated for their thyroids were estimated only by using the images of Dual time I-131 whole body scan. Also, the correlations with the effective life, GFR, and serum creatinine were examined. This study might be utilized for a study on optimization for the period of hospitalization of patients treated by high dose of I-131 and on evaluation for internal absorbed dose of MIRD schema in application of the effective half life.

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Effect of Low Magnetic Field on Dose Distribution in the Partial-Breast Irradiation (부분유방 방사선조사 시 저자기장이 선량분포에 미치는 영향)

  • Kim, Jung-in;Park, So-Yeon;Lee, Yang Hoon;Shin, Kyung Hwan;Wu, Hong-Gyun;Park, Jong Min
    • Progress in Medical Physics
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    • v.26 no.4
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    • pp.208-214
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    • 2015
  • The aim of this study is to investigate the effect of low magnetic field on dose distribution in the partial-breast irradiation (PBI). Eleven patients with an invasive early-stage breast carcinoma were treated prospectively with PBI using 38.5 Gy delivered in 10 fractions using the $ViewRay^{(R)}$ system. For each of the treatment plans, dose distribution was calculated with magnetic field and without magnetic field, and the difference between dose and volume for each organ were evaluated. For planning target volume (PTV), the analysis included the point minimum ($D_{min}$), maximum, mean dose ($D_{mean}$) and volume receiving at least 90% ($V_{90%}$), 95% ($V_{95%}$) and 107% ($V_{107%}$) of the prescribed dose, respectively. For organs at risk (OARs), the ipsilateral lung was analyzed with $D_{mean}$ and the volume receiving 20 Gy ($V_{20\;Gy}$), and the contralateral lung was analyzed with only $D_{mean}$. The heart was analyzed with $D_{mean}$, $D_{max}$, and $V_{20\;Gy}$, and both inner and outer shells were analyzed with the point $D_{min}$, $D_{max}$ and $D_{mean}$, respectively. For PTV, the effect of low magnetic field on dose distribution showed a difference of up to 2% for volume change and 4 Gy for dose. In OARs analysis, the significant effect of the magnetic field was not observed. Despite small deviation values, the average difference of mean dose values showed significant difference (p<0.001), but there was no difference of point minimum dose values in both sehll structures. The largest deviation for the average difference of $D_{max}$ in the outer shell structure was $5.0{\pm}10.5Gy$ (p=0.148). The effect of low magnetic field of 0.35 T on dose deposition by a Co-60 beam was not significantly observed within the body for PBI IMRT plans. The dose deposition was only appreciable outside the body, where a dose build-up due to contaminated electrons generated in the treatment head and scattered electrons formed near the body surface.

A Thermodynamical Study on the Phase Formation and Sequence by Ion Beam Mixing in Al/Pd System (이온선 혼합에 의한 Al/Pd계의 상형성 및 전이에 관한 열역학적 연구)

  • Choi, Jeong-Dong;Hong, Jin-Seok;Kwak, Joon-Seop;Chi, Eung-Joon;Park, Sang-Wook;Baik, Hong-Koo;Chae, Keun-Hwa;Jung, Sung-Mun;Whang, Chung-Nam
    • Journal of the Korean Vacuum Society
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    • v.2 no.2
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    • pp.209-219
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    • 1993
  • Evaporated Al/Pd thin films were irradiated with various doses to produce intermetallic compounds. In order to study the first phase formation and phase sequence, RBS and TEM studies have been used. It was found that the initial phase formed by irradiation of $5{\times}10^{15}Ar^+/cm^2$ was $Al_3Pd_2$, while $1.5{\times}10^{16}Ar^+/cm^2$ gave the subsequent phase of AlPd. This phenomenon was analysed using effective heat of formation (${\Delta}$H') model. The experimental results agree with that predicted by effective heat of formation model. This model has been extended to predict the first phase formation and phase sequence by ion beam mixing in metal/Si systems as well as metal-metal systems.

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Determination of shear wave velocity profiles in soil deposit from seismic piezo-cone penetration test (탄성파 피에조콘 관입 시험을 통한 국내 퇴적 지반의 전단파 속도 결정)

  • Sun Chung Guk;Jung Gyungja;Jung Jong Hong;Kim Hong-Jong;Cho Sung-Min
    • 한국지구물리탐사학회:학술대회논문집
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    • 2005.09a
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    • pp.125-153
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    • 2005
  • It has been widely known that the seismic piezo-cone penetration test (SCPTU) is one of the most useful techniques for investigating the geotechnical characteristics including dynamic soil properties. As the practical applications in Korea, SCPTU was carried out at two sites in Busan and four sites in Incheon, which are mainly composed of alluvial or marine soil deposits. From the SCPTU waveform data obtained from the testing sites, the first arrival times of shear waves were and the corresponding time differences with depth were determined using the cross-over method, and the shear wave velocity profiles (VS) were derived based on the refracted ray path method based on Snell's law and similar to the trend of cone tip resistance (qt) profiles. In Incheon area, the testing depths of SCPTU were deeper than those of conventional down-hole seismic tests. Moreover, for the application of the conventional CPTU to earthquake engineering practices, the correlations between VS and CPTU data were deduced based on the SCPTU results. For the empirical evaluation of VS for all soils together with clays and sands which are classified unambiguously in this study by the soil behavior type classification Index (IC), the authors suggested the VS-CPTU data correlations expressed as a function of four parameters, qt, fs, $\sigma$, v0 and Bq, determined by multiple statistical regression modeling. Despite the incompatible strain levels of the down-hole seismic test during SCPTU and the conventional CPTU, it is shown that the VS-CPTU data correlations for all soils clays and sands suggested in this study is applicable to the preliminary estimation of VS for the Korean deposits and is more reliable than the previous correlations proposed by other researchers.

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