Browse > Article

Interpretation of Uranium Bioassay Results with the ICRP Respiratory Track and Biokinetic Model  

Kim, H.K. (Dept. of Nuclear Engineering Hanyang University)
Lee, J.K. (Dept. of Nuclear Engineering Hanyang University)
Publication Information
Journal of Radiation Protection and Research / v.28, no.1, 2003 , pp. 43-50 More about this Journal
Abstract
This study describes a practical method for interpretation of bioassay results of inhaled uranium to assess the committed effective doses both for chronic and acute intake situations. Organs in the body were represented by a series of mathematical compartments for analysis of the behavior of uranium in the body according to the gastrointestinal track model, respiratory track model and biokinetic model recommended by the ICRP. An analytical solutions of the system of balance equations among the compartments were obtained using the Birchall's algorithm, and the urinary excretion function and the lung retention function of uranium were obtained. An initial or total intakes by intake modes were calculated by applying excretion and retention functions to the urinary uranium concentration and the lung burden measured with a lung counter. The dose coefficients given in ICRP 78 are used to estimate the committed effective doses from the calculated intakes.
Keywords
compartment models; uranium; excretion function; retention function; internal exposure; bioassay; intake;
Citations & Related Records
연도 인용수 순위
  • Reference
1 ICRP, Age-dependent Doses to Members of the Public from Intake of Radionudides: Part.5 Ingestion Dose Coefficients, International Commission on Radiological Protection, ICRP Publication 67(1993)
2 ICRP, Age-dependent doses to Members of the Public from Intake of Radionuclides: Part 5 Ingestion Dose Coefficients, International Commission on Radiological Protection, ICRP Publication 69(1994)
3 L. Bertelli, A. Puerta, M. E. Wrenn and J. L. Lipsztein, 'Bioassay interpretation and dosimetry using specific absorption parameters for UO$_{2}$ and U$_{3}$O$_{8}$,' Radiat. Protect. Dosim., 79, 1-4, 111-113(1998)   DOI
4 E. Ansoborlo, A. Hodgson, G. N. Stradling, S. Hodgson, H. Metivier, M. H. Henge-Napoli, N. S. Jarvis and A. Birchall, 'Exposure Implications for Uranium Aerosols Formed at a New Laser Enrichment Facility: Application of the ICRP Respiratory Track and Systemic Model,' Radiat. Protect. Dosim., 79, 1-4, 23-27(1998)   DOI
5 A. Birchall and A. C. James, 'A Microcomputer Algorithm for Solving First-order Compartment Models Involving Recycling,' Health Pltys., 56, 6, 857-868(1989)
6 J. M. Barber and R Forrest, A model for uranium lung clearance at the Y-12 plant, Oak Ridge Y-12 Plant, Y/DQ- 39(1992)
7 M. D. Hoover, G. J Newton, R. A. Guilmette, R. J Howard, R. N. Ortiz, J M. Thomas, s. M. Trotter and E. Ansoborlo, 'Characterization of Enriched Uranium Dioxide Particles from a Uranium Handling Facility', Radiat. Protect. Dosim., 79, 1-4, 57-62(1998)
8 ICRP, 1990 Recommendations of the International Commission on Radiological Protection, International Commission on Radiological Protection, ICRP Publication 60(1991)
9 R. W. Leggett, K. F. Eckerman and L. R. Williams, 'An Elementary Method for implementing Complex Biokinetic Models', Health Phys., 64, 3, 260-271(1993)
10 J L. Malarbet, 'Calculations of Radionuclide Organ Retentions from ICRP Biokinetic Recycling Models', Radiat. Protect. Dosim., 79, 1-4, 379-381(1998)
11 ICRP, Limits for Intakes of Radionuclides by Workers, International Commission on Radiological Protection, ICRP Publication 30(1978)
12 NRPB, Time-dependent Functions to Represent the Bioassay Quantities Given in ICRP Publication 78, National Radiological Protection Board, NRPB-M824(1998)
13 ICRP, Individual Monitoring for Internal Exposure of Workers Replacement of ICRP Publication 54, International Commission on Radiological Protection, ICRP Publication 78(1997)
14 Brice L. R, Stuart L. H., Clayton R L., W. G. Mansfield, L. H. Munson, E. R Wagner and E. J. Vallario, Health physics manual of good practices for uranium facilities, Idaho National Engineering Laboratory, DE88-013620(1988)
15 ICRP, Individual Monitoring for Intakes of Radionuclides by Workers: Design and Interpretation, International Commission on Radiological Protection, ICRP Publication 54(1987)
16 A Luciani, H. Doerfel and E. Polig, 'Sensitivity Analysis of the Urinary Excretion of Plutonium,' Radiat. Protect. Dosim., 93, 2, 179-183(2001)
17 H. Schieferdecker, H. Horst, H. Doerfel, W. Rudolph and R Anton, 'Inhalation of U aerosols from UO$_{2}$ fuel element fabrication,' Health Phys., 48(1), 29-47(1985)
18 ICRP, Human Respiratory Track Model for Radiological Protection, International Commission on Radiological Protection, ICRP Publication 66(1993)