• Journal of Acupuncture Research
• /
• v.21 no.1
• /
• pp.211-225
• /
• 2004

목적 : 류마티스 관절염 환자의 골 파괴에 중요한 역할을 하는 것으로 알려진 Matrix Metalloproteinase-1(MMP-1) 유전자의 단일 염기 다형성을 분석하고, 나아가 봉독약침 치료에 대한 반응과의 연관성을 조사하기 위하여 본 연구를 시행하였다. 방법 : 미국류마티스학회의 류마티스 관절염 기준에 해당하는 122명의 한국인 류마티스 관절염 환자와 건강한 92명의 대조군을 대상으로 pyrosequencing 방법을 이용하여 MMP-1 유전자의 -519 위치의 다형성을 비교 분석하였으며, 류마티스 관절염 환자군을 다시 유전자 유형에 따라 동통 관절수, 종창 관절수, 조기 강직, 통증 강도, 삶의 질 평가도구인 HAQ, 환자 및 의사의 전반적 질병상태 평가, ESR, CRP 등의 항목을 치료 전후 평가하여 비교 분석하였다. 결과 : 1. 류마티스 환자군과 건강한 대조군간에 MMP-1 유전자의 단일 염기 다형성의 유전자형의 분포와 대립유전자 발현 빈도에 통계적으로 유의한 차이가 나타났으며, 이는 MMP-1 유전자 다형성이 한국인 류마티스 관절염 환자의 질병 감수성과 관련이 있음을 추정할 수 있다. 2. 각 유전자형 그룹간 치료전 질병의 중증도 평가에서 임상 평가와 혈액의 급성 염증 반응물질 평가에서 통계적으로 유의한 차이는 없었다. 3. 급성 염증 반응의 지표인 ESR과 CRP level의 봉독약침 치료 전후 변화는 MMP-1의 유전자 다형성과 유의한 연관이 없었다. 4. 각 유전자형 그룹간의 치료 전후 질병 호전도 비교에서, AA 유전자형이 종창 관절수 평가에서 더나은 호전을 보였으며, 다른 모든 평가에서는 통계적으로 유의한 차이가 없었으며, 향후 관련 유전자와의 연관성 연구가 필요하다고 사료된다.

• The Journal of the Korea Contents Association
• /
• v.22 no.10
• /
• pp.359-373
• /
• 2022

The purpose of this study was to develop evidence-based practice guideline for rapid response to acute deterioration of hospitalized patients. The guideline was developed according to the Clinical Practice Guideline Adaptation Manual. and evaluated using AGREE II tool. The guidelines were checked content validation by an expert group, final 130 recommendations in 5 sections including management, recognition, activation, response, and evaluation. The average of the overall practical application to the guidelines was 4.41±0.78 out of 5, which showed high applicability in clinical work.

• Korean Journal of Forensic Psychology
• /
• v.12 no.2
• /
• pp.223-251
• /
• 2021

Statement analysis is a technique that examines the credibility of a statement by scientifically analyzing problems and psychological characteristics that appear in the content of the statement. The statement analysis report is prepared, submitted, and used for legal judgments when there is a suspicion of sexual abuse for children(under 13 years of age) and persons with disabilities since it is usually difficult to secure physical evidence nor eyewitnesses. However, the criteria for evaluating the quality of a statement analysis report or testimony are not available in Korea. Although forensic experts and professional organizations in North America and Europe are providing recommendations and guidelines for preparing forensic assessment reports, qualitative analysis research studies for forensic reports revealed a number of problems such as missing or poorly described essential information and lack of logical connection between evaluation results and forensic opinions. Therefore, forensic evaluation guidelines and forensic reports submitted to the courts in the United States, as well as the Structured Quality assessment of eXpert testimony (SQX-12) developed in Sweden were examined to suggest the Korean version of quality evaluation criteria for statement analysis report and testimony. This criteria can be used to improve effectiveness of forensic reports within criminal justice system and used as a guideline to assess the quality forensic reports or expert testimony prepared by experts. However, this criteria do not guarantee the reliability of the statement itself.

• Therapeutic Science for Rehabilitation
• /
• v.8 no.2
• /
• pp.7-30
• /
• 2019

Objective : The purpose of this study was to analyze the format and effects of lifestyle intervention provided to community dwelling older adults. This systematic review was written following the PRISMA guideline. Methods : The National Digital Science Library(NDSL), RISS, PubMed, and CINAHL were used to search for articles published from January 2008 to December 2017. In total, 20 articles were selected for the analysis and the risk of bias was screened through the Physiotherapy Evidence Database Scale. Lifestyle interventions in the articles were classified according to the disease of the participants. Results : Major contents of the lifestyle interventions were increased physical activity like moderately intensive exercise and education or training to help participants have a healthy diet. Of the 20 articles, 17 included more than 2 types of contents. Examining biochemical factors was the most common measurement among the multifaceted measurements used to assess the effects of lifestyle interventions. The results of the lifestyle interventions described in each article did not indicate congruent effects. 14 of the 20 articles reported the lifestyle interventions had significant effects. Conclusions : The results of this study could help practitioners select the contents of and provide lifestyle interventions to older adults. Further study on the various applications of lifestyle interventions in a community setting is necessary.

• The Journal of the Korea institute of electronic communication sciences
• /
• v.10 no.1
• /
• pp.47-54
• /
• 2015

Recently, rapid urbanization and industrialization had increased the air pollution in major cities by increasing the fuel consumption. Air pollution models have been widely used for air quality management in many countries. Also, a lot of related studies have been conducted using air dispersion models. In this study, The meteorological preprocessing program was developed to convert the korea meteorological data to the U.S. meteorological data and to expand the usability of air dispersion models of U.S. EPA. In addition, the usability evaluation was carried out through a case study. In the results of the evaluation of the program, this program was accurately convert the Korea meteorological data to the U.S. meteorological data, and the prediction was carried out without a error in air quality modeling. Therefore, the program showed a high utilization as meteorological data pre-processing tool.

• Journal of the Korean GEO-environmental Society
• /
• v.15 no.11
• /
• pp.21-27
• /
• 2014

In this study, the prediction methods for the crest settlement after impounding and the maximum internal settlement during dam construction were proposed through the analysis on settlement data at 46 monitored points of 37 Center-Cored Rockfill Dams (CCRDs). Results from this analysis provided that the crest settlement increases with elapsed time, and from the relationship between the dam height and the maximum internal settlement during dam construction, it is confirmed that the internal settlement was largely evaluated when the coarse-grained material was used as the dam core. This internal settlement increased in proportion to the dam height. In addition, the crest settlement of the CCRD with the core compacted with fine-grained material was relatively large. It is expected that the results of this study would provide the practical tool for the design, construction and management of CCRDs.

• Journal of Korean Biological Nursing Science
• /
• v.14 no.3
• /
• pp.221-230
• /
• 2012

Purpose: Quality of nursing research should be evaluated before it is applied as an evidence for evidence-based nursing practice. This study attempted to analyze and to compare tools for the quality assessment and reporting standards of nursing research using CONSORT and STROBE checklist by types of research design. Methods: We searched the tools for quality assessment in nursing research based on the National Evidence-based Healthcare Collaborating Agency (NECA) publication. Then, we analysed and compared the tools for quality evaluation by types of research design. Results: According to the analysis using CONSORT checklist, ROB shows coherence in 17 items, Jadad shows coherence in 3 items, SIGN (for RCT) shows coherence in 26 items, and Downs & Black shows coherence in 24 items. According to the analysis using STROBE checklist, MINORS shows coherence in 25 items, NOS shows coherence in 21 items, SIGN (for Cohort studies & Case-control studies) shows coherence in 29 items, and RoBANS shows coherence in 21 items. Conclusion: Based on our analysis, we recommend that nursing researchers should report according to the reporting standards of tools for quality evaluation. We hope that our analysis can be helpful to develop evidence-based nursing.

• Korean Journal of Clinical Laboratory Science
• /
• v.56 no.2
• /
• pp.105-114
• /
• 2024

Clinical laboratories endeavor to secure quality by establishing effective quality management systems. However, laboratory environments are complex, and single quality control procedures may inadequately detect many errors. Patient-based real-time quality control (PBRTQC) is a laboratory tool that monitors the testing process using algorithms such as Bull's algorithm and several variables, such as average of normal, moving median, moving average, and exponentially weighted moving average. PBRTQC has many advantages over conventional quality control, including low cost, commutability, continuous real-time performance monitoring, and sensitivity to pre-analytical errors. However, PBRTQC is not easily implemented as it requires statistical algorithm selection, the design of appropriate rules and protocols, and performance verification. This review describes the basic concepts, methods, and procedures of PBRTQC and presents guidelines for implementing a patient-based quality management system. Furthermore, we propose the combined use of PBRTQC when the performance of internal quality control is limited. However, clinical evaluations were not conducted during this review, and thus, future evaluation is required.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.4 no.4
• /
• pp.346-351
• /
• 2003

In spite of the size and complexity of software becomes large and complicated, the demand of rapid development, cost reduction, good productivity and good quality software is increasing in these days. Many methods were proposed for efficient software development such as various Case tools. Metrics, Process improvement model (CMM, SPICE, ISO9000) and etc. However, most of them we useful to manage the whole projects rather than an individual programming. In this paper, we introduced a system for quality assessment and complexity metrics for Java programs to assess the individual programmer's quality rather than team's quality. This system shows not only the metrics value for quality assessment but also the source code and the soucture of classes simultaneously.

• The Journal of the Korea Contents Association
• /
• v.19 no.6
• /
• pp.524-540
• /
• 2019

We researched about the relationship among the Purpose of Assessment Certificate System, the preparation result, certificate, and, the performance of the assessment certificate on the purpose of the empirical analysis. For the testing of a research model, we tested 170 samples that our colleges tested by The Assessment Certificate System. As a result of the analysis; there are positive and causal effect relationships among the three variables. This study result will expansion and help to maintain performance growth in the college. In the future, the research about the improvement of management performance are needed.