• Title/Summary/Keyword: 지질성분

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Synergistic Effects of N-methyl-2-pyrrolidone on Skin Permeation of a Hydrophobic Active Ingredient (N-methyl-2-pyrrolidone 제제의 경피흡수촉진효과)

  • Lee, Geun-Soo;Lee, Dong-Hwan;Kim, Kyoung-Bum;Ko, Hyun-Joo;Pyo, Hyeong-Bae
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.36 no.2
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    • pp.115-120
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    • 2010
  • The formidable barrier property of the stratum cornemum and the high hydrophilicity of active ingredient make it difficult to permeate through the skin and reach to its site of action. The aim of this study was to investigate the effect of chemical penetration enhancers on the skin permeation of a hydrophilic cosmetic active ingredient, such as arbutin. The enhancing effects of N-methyl-2-pyrrolidone (NMP) on the permeation of a hydrophilic cosmetic active ingredient were evaluated by using Franz diffusion cell. The study indicated that NMP has considerable influence on the skin permeability. NMP was not only the most effective enhancer but also increased the skin permeability of arbutin approximately 1.3~1.5 fold compared with control without penetration enhancer. The lag time did not change with NMP, which suggested no effect of NMP on skin lipid fluidity. This suggest that arbutin co-permeated with NMP. The results indicate NMP is effective enhancer of a hydrophilic cosmetic active ingredient in penetration, with potential applications for drug delivery system.

Water Properties of Electrolytic Machine by Stainless Diaphragm and Effects of Electrolytic Ice Water Storage For Keeping Freshness of Squid, Todarodes pacificus (스테인레스 극판을 이용한 전해수장치의 수질특성과 오징어 선도유지를 위한 전해수 빙장 효과)

  • Lee, Nahme-Gull
    • Journal of Fisheries and Marine Sciences Education
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    • v.18 no.3
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    • pp.293-301
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    • 2006
  • This study was undertaken to prolonging the freshness in Squid(Todarodes pacificus) on the effects of ice storage methods(tap water ice, electrolytic water ice) using stainless diaphragm electrolytic instrument and also test an efficiency of instrument. Basically, stainless diaphragm electrolytic instrument studied for changes of pH on difference water flow and ampere. The lower water flower and higher ampere made low pH on acid part of electrolytic instrument. Squid samples were stored in tap water ice, acid part of electrolytic water and base part of electrolytic water and used in studying the changes of VBN and skin color through storage. Acid water had strong sterilization effects and VBN was lower levels of acid water than the others. Base water had not sterilization effects. Tap water ice storage was more sterilizing effects than base water ice storage but less effects than acid water ice storage. Lightness of Squid skin showed getting decrease at storage of ice water of all storage methods but acid water ice storage showed more retarding than the other two storage. From these results, it could be suggested that acid electric water ice storage is effective in extendance the shelf-life of squid at chilled storage.

Anti-Obesitic Effects of Cathepsin S Inhibitory Fraction Derived from Paecilomyces tenuipes in Mice Fed a High-Fat Diet (고지방식이를 섭취한 쥐에서 눈꽃동충하초 유래 cathepsin S 저해 분획의 비만 억제 효과)

  • Heo, Keon;Myoung, Kil-Sun;Lee, Jung-Hee;Huh, Chul-Sung
    • Korean Journal of Food Science and Technology
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    • v.41 no.4
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    • pp.446-451
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    • 2009
  • In this study, cathepsin S (CTSS) inhibitory fraction was isolated from Paecilomyces tenuipes and anti-obesitic effects of the fraction were evaluated in mice, fed a high-fat diet. Hot water extract of P. tenuipes (DHW) was divided into 2 fractions, water eluate fraction (DHP1) and methanol eluate fraction (DHP2) using Diaion HP-20. $IC_{50}$ values for DHW, DHP1 and DHP2 against CTSS were 108.7, 890.3 and 2.3 ${\mu}g$/mL, respectively. To evaluate anti-obesitic effects of the fractions, each fraction was administrated orally to C57BL/6 mice for 4 weeks with a high-fat diet. DHP2 had the highest inhibitory effect on CTSS activity, causing serious reduction in weight gain, a reduction in the amount of adipose tissue and in serum lipids levels. These results suggest that the inhibition of CTSS by compounds derived from P. tenuipes may be effective in preventing and in ameliorating obesity.

Lipolysis Effect of Daucosterol Isolated from Mulberry (Morus alba) Leaves (뽕잎으로부터 순수분리한 daucosterol의 lipolysis 효과)

  • Li, Ke;Lee, Mi Lim;Que, Lu;Li, Mae;Kang, Jum Soon;Choi, Yung Hyun;Kim, Kyung Mi;Jung, Jae-Chul;Hwang, Dae Youn;Choi, Young Whan
    • Journal of Life Science
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    • v.27 no.12
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    • pp.1500-1506
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    • 2017
  • Plants are reservoirs of naturally occurring chemical compounds and of structurally diverse bioactive molecules. The aim of this investigation was to screen for the presence of phytochemicals responsible for the lipolysis activity in mulberry (Morus alba) leaves, which are important in traditional Asian medicinal plants. Powdered mulberry leaves were extracted with hexane, ethyl acetate, and methanol. Daucosterol was isolated from the EtOAc extract of mulberry leaves, and its structure was elucidated by NMR spectral analyses. The NMR assignments for the compound were determined using $^1H$, $^{13}C$, DEPT, COSY, HSQC, and HMBC NMR spectral data. Daucosterol showed a concentration-dependent lipolysis activity that may impart medicinal properties that can be exploited by medical practitioners for the treatment of various diseases. However, further studies should be conducted to elucidate additional mechanisms of daucosterol.

Quality Factors and Functional Components in the Edible Seaweeds I. Distribution of n-3 Fatty Acids in 10 Species of Seaweeds by Their Habitats (식용 해조류의 품질구성요인과 그 기능성 성분 I. 서식지에 따른 10종 해조류의 n-3 지방산의 분포)

  • 정보영;조득문;문수경;변재형
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.22 no.5
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    • pp.621-628
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    • 1993
  • Total lipid contents from 10 species of marine algae(2 green, 5 brown, and 3 red algae) collected from different places in Korea were examined and their fatty acid compositions were compared among species and habitats. Total lipid(TL) was prominent in green laver(about 7.3~10.1%) of the green algae, in sea mustard and seaweed fusiforme(about 3.1~4.8%) of the brown algae and purple laver(about 4.9~6.4%) of the red algae. Sea mustard and seaweed fusiforme collected at Chungmu contained a relatively high level of TL than that at Yosu and Kijang. The TL content of purple laver showed the highest portion in that collected at Nakdong. Green algae comprised the majority of n-3 fatty acids(29.0~66.3%), which mainly consisted of 16 : 4(n-3) (or 16 : 3 (n-3)), 18 : 3(n-3) and 18 : 4(n-3). Brown algae accounted for a low level of n-3 fatty acids(17.9~36.5%) mainly 18 : 4(n-3), 18 : 3(n-3) and 20 : 5(n-3), whereas the brown algae contained a significant level of n-6 fatty acids(7.23~26.5%) such as 20 : 4(n-6) and 18 : 2(n-6). In the case of red algae, the n-3 fatty acids consisted mostly of 20 : 5(n-3) which scored 53% of polyenoic acids in purple laver collected at Nakdong. The proportion of n-3 fatty acids in algae belonging to the same species was higher in algae of high TL contents. Consequently, TL and n-3 fatty acid levels from the seaweeds studied in this paper were different from their habitats.

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Effects of Cultured Oyster Powder on Food Quality of Soybean Pastes (양식산 굴 첨가가 된장의 품질에 미치는 영향)

  • Kim, Jin-Soo;Heu, Min-Soo
    • Applied Biological Chemistry
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    • v.47 no.2
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    • pp.208-215
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    • 2004
  • As a part of a study on the effective use of cultured oyster, oyster powder-added soybean pastes were prepared and its characteristics were examined. As the concentration of oyster powder added to commercial soybean paste was increased, the moisture level decreased, the crude and amino nitrogen content increased with no change in the salinity and titratable acidities. Also, the color of the soybean paste changed to a darker color as the concentration of oyster powder added to commercial soybean paste increased. Judging from the results of the above experiment and sensory evaluation, the optimal additive concentration of oyster powder to commercial soybean paste was revealed as 9%. The total amino acid content of oyster powder-added soybean paste was 2% higher than that of commercial soybean paste. The ratio of calcium and phosphorus of oyster powder-added soybean paste was about 1:2-2:1, an improvement in calcium absorption as compared to commercial soybean paste. Functional fatty acids, such as 20:5n-3 and 22:6n-3, were not detected in commercial soybean paste but detected in oyster powder-added soybean paste. The major free amino acids in oyster powder-added soybean paste were glutamic acid and aspartic acids. According to the above results, the nutritional, functional and taste properties of commercial soybean paste were improved while reducing preparation time of the housewife.

Classification According to Site of Action of Paddy Herbicides Registered in Korea (국내 수도용 제초제의 작용기작별 분류)

  • Park, Jae-Eup;Kim, Sang-Su;Kim, Young-Lim;Kim, Min-Ju;Ha, Heun-Young;Lee, In-Yong;Moon, Byung-Chul;Ihm, Yang-Bin
    • Weed & Turfgrass Science
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    • v.3 no.3
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    • pp.165-173
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    • 2014
  • This review study was conducted to recommend the effective use of herbicide mixtures in Korea. The herbicide ingredients by Herbicide Resistancce Action Committee (HRAC) was classified into 23 groupes according to the mode of action (acetyl CoA carboxylase inhibitors, acetolactate synthase, photosystem I and II inhibitors, protoporphyrinogen oxidase inhibitors, carotenoid biosynthesis inhibitors, enolpyruvyl shikimate-3-phosphate synthase inhibitors, glutamine synthetase inhibitors, dihydropteroate synthetase inhibitors, mitosis inhibitors, cellulose inhibitors, oxidative phosphorylation uncouplers, fatty acid and lipid biosynthesis inhibitors, synthetic auxins, auxin transport inhibitors and potential nucleic acid inhibitors or non-descript mode of action). The rice herbicide mixtures registered in Korea were classified based on the guideline of HRAC. Accordingly, such a classification system for resistance management can help to avoid continuous use of the herbicide having the same mode of action in the same field.

Feldspar Diagenesis and Reseuoir History of the Miocene Temblor Formation, Kettleman North Dome, California, U.S.A. (미국 캘리포니아주 케틀만 노스돔의 마이오세 템블러층에서 장석의 속성작용과 저류암의 발달사)

  • Lee Yong Il;Boles James R.
    • The Korean Journal of Petroleum Geology
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    • v.3 no.1 s.4
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    • pp.16-27
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    • 1995
  • The Early Miocene Temblor Formation forms an important sandstone reservoir at Kettleman North Dome oil field, California. Sandstones are mostly arkosic in composition except deepest sandstones containing much volcanic rock fragments. Arranged in paragenetic sequence prior to feldspar alteration, the Temblor sandstones contain cements of early calcite, dolomite, quartz, albite, mixed-layer ohloriteismectite (C/S) and smectite, and anhydrite. Diagenetic changes associated with feldspar are albitization of plagioclase, late calcite and laumontite cementation and grain replacement, plagioclase dissolution, and kaolinite cementation. Plagioclase albitization and late calcite and laumontite cementation in Temblor sandstones occurred at the time of maximum burial with temperatures up to $130^{\circ}C$. Volcanic plagioclases were selectively albitized. Most diagenetic changes are interpreted to have occurred before the maior uplift which occurred within the last one million years ago. Since then to the time of hydrocarbon emplacement plagioclase dissolution and kaolinite cementation occurred. This reaction occurred in relatively closed system due to the occurrence of kaolinite next to the site of plagioclase dissolution. Unaltered part of volcanic plagioclase and plutonic plagioclase which escaped albitization during maximum burial were preferentially dissolved to make plagioclase porosity. Secondary porosity resulting from dissolution of plagioclase and carbonate and anhydrite cements was mainly produced by formation waters containing organic acids released during atagenesis of organic matter.

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Synthesized Oil Manufacturing Technology from Natural Gas, GTL (천연가스로부터 합성유 제조 기술, GTL(Gas To Liquids))

  • Bae, Ji-Han;Lee, Won-Su;Lee, Heoung-Yeoun;Kim, Yong-Heon
    • The Korean Journal of Petroleum Geology
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    • v.14 no.1
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    • pp.45-52
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    • 2008
  • The GTL(Gas to Liquids) technology, manufacturing synthesized oil from natural gas, had been developed about 1920 for the military purpose by Fischer and Tropsch, German scientists. And 1960, Sasol company had started commercializing the FT(Fischer-Tropsch) synthesis technology, for the transport fuel in South Africa. Until a recent date, the commercialization of GTL technology had been delayed by low oil price. But concern about depletion of petroleum resources, and development in synthesizing technology lead to spotlight on the GTL businesses. Especially, Qatar, which has rich natural gas fields, aims at utilizing natural gas like conventional oil resources. Therefore, around this nation, GTL plants construction has been promoted. There are mainly 3 processes to make GTL products(Diesel, Naphtha, lube oil, etc) from natural gas. The first is synthesis gas generation unit reforming hydrogen and carbomonoxide from natural gas. The second is FT synthesis unit converting synthesized gas to polymeric chain-hydrocarbon. The third is product upgrading unit making oil products from the FT synthesized oil. There are quite a little sulfur, nitrogen, and aromatic compounds in GTL products. GTL product has environmental premium in discharging less harmful particles than refinery oil products from crude to the human body. In short, the GTL is a clean technology, easier transportation mean, and has higher stability comparing to LNG works.

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Effect of Insoluble Dietary Fiber Extracted from Salicornia herbacea L. on Large Intestinal Function in Rats (불용성 함초 식이섬유의 섭취가 흰쥐 장기능에 미치는 효과)

  • Kim, Soo-Hwan;Kim, Sook-Ja;Lee, Hyeong-Seon
    • Korean Journal of Food Science and Technology
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    • v.46 no.5
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    • pp.648-654
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    • 2014
  • This study investigated the effect of insoluble dietary fibers extracted from Salicornia herbacea L. (S. herbacea) on the improvement of intestinal function in rats. Sprague-Dawley rats were fed on diet containing 5% and 10% S. herbacea dietary fiber (SHDF) for four weeks. Rats receiving the SHDF diet showed a significant decrease in their triglyceride levels and an increase in HDL-cholesterol levels. In addition, compared with the control group, the SHDF group showed a significant increase in the total quantity of the feces and its moisture content. The intestinal transit time of the feces was also shorter in this group. The pH of the feces decreased in all the other experimental groups. Particularly, the bile acid content of the feces and the thicknesses of the mucus layers showed significant recovery on SHDF intake. These results suggest that dietary fiber isolated from S. herbacea has a marked effect on the improvement of bowel function in rats with loperamide (2 mg/kg)-induced constipation.