• Title/Summary/Keyword: 지지체

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Characteristic Analysis and Fabrication of Bioceramic Scaffold using Mixing Ratios of TCP/HA by Fused Deposition Modeling (압출 적층 조형 기술을 이용한 TCP/HA 의 혼합비율에 따른 바이오 세라믹 인공지지체의 제작 및 특성 연구)

  • Sa, Min-Woo;Kim, Jong Young
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.38 no.11
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    • pp.1273-1281
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    • 2014
  • Tissue engineering is an emerging research field that has the potential to restore, regenerate and repair damaged bone tissue and organs. Tricalcium phosphate and hydroxyapatite biomaterials-based calcium phosphate are excellent materials that have both osteoconduction and biocompatibility for bone tissue regeneration. In this study, solution structures were successfully fabricated using a fused deposition modeling system based on deposition and heating devices. The morphology characteristics of the bioceramic scaffolds sintered at a temperature of $1,300^{\circ}C$ were analyzed by scanning electron microscopy. The effects of various blended TCP/HA ratio on the microstructure and shrinkage were studied. The mechanical properties of the scaffolds were measured using a compression testing machine from stress-strain curves on the crosshead velocity of 1 mm/min. The fabricated scaffolds were evaluated by cell proliferation tests of MG-63 cells. The results of this study suggest that the blended TCP(75 wt%)/HA(25 wt%) scaffold is an appropriate scaffold for bone tissue regeneration.

Effect of Support Membrane Property on Performance of Forward Osmosis Membrane (지지체 특성이 정삼투막 성능에 미치는 영향)

  • Jeong, Bo-Reum;Kim, Jong-Hak;Kim, Beom-Sik;Park, Yoo-In;Song, Du-Hyun;Kim, In-Chul
    • Membrane Journal
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    • v.20 no.3
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    • pp.235-240
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    • 2010
  • The aim of this paper is to evaluate and compare the performances of forward osmosis (FO) membranes using different materials. The FO membranes were synthesized using interfacial polymerization method on hydrophobic polysulfone (PSf) and relatively hydrophilic polyethersulfone (PES) supports. The FO performance such as flux and back diffusion was measured. The resulting fluxes of PSf and PES FO membranes were $4.3\;L/m^2hr$ and $17.8\;L/m^2hr$, respectively. The flux of the PES FO membrane was higher than that of the PSf FO membrane. The results indicated that hydrophillictity of the support membrane is important for increasing flux in FO process. Moreover, with decreasing the support layer thickness, flux increased considerably.

Study on Characteristics of Sliding Support for Fuel Rod (이동 가능한 연료봉 지지부의 특성 고찰)

  • Song, Kee-Nam;Lee, Sang-Hoon
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.35 no.2
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    • pp.201-206
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    • 2011
  • A spacer grid assembly is one of the most important structural components of the nuclear fuel assembly of a pressurized water reactor (PWR), and it affects the performance of the fuel assembly. The primary design requirement is that the mechanical integrity of the fuel rod should be maintained by the spacer grid assembly during the operation of the reactor. It was known that fretting damage to the fuel rod can be reduced by adjusting the relative moving displacement between the fuel rod and its support. In this study, we used the finite element method to evaluate the characteristics of a sliding support designed to reduce fretting damage of fuel rods.

A Study on Composite EM Absorber's Absorption Characteristics Using Natural Lacquer by Binder (옻을 지지재로 사용한 복합형 전자파 흡수체의 흡수 특성에 관한 연구)

  • Choi, Dong-Han
    • Proceedings of the Korea Electromagnetic Engineering Society Conference
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    • 2003.11a
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    • pp.622-629
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    • 2003
  • Generally, a silicone rubber and a chloride polyethylene(CPE) have been used for the development of high-performance composite EM(ElectroMagnetic) wave absorber. In this study, the EM wave absorption abilities for natural lacquer which is newly suggested in this study as a binder for composite EM wave absorber were investigated to develop an improved EM wave absorber In addition, MnZn ferrite composite EM wave absorber mixed with the natural lacquer were prepared and their absorption ability was also investigated. MnZn ferrite composite EM wave absorber which employs the natural lacquer as a binder showed an improved EM wave absorption characteristics in comparison with the conventional binder such as a silicone rubber and a chloride polyethylene(CPE). The matching frequency and the absorption ability of EM wave absorber mixed with natural lacquer can be controled the change of the thickness of them.

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Preparation and Characterization of Ipriflavone-Loaded Poly(L-lactide-co-glycolide) Scaffold for Tissue Engineered Bone (조직공학적 골을 위한 애프리플라본을 함유한 다공성 지지체의 제조 및 그 특성)

  • Jang, Ji-Wook;Lee, Bong;Han, Chang-Whan;Lee, Il-Woo;Lee, Hai-Bang;Khang, Gil-Son
    • Polymer(Korea)
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    • v.27 no.3
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    • pp.226-234
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    • 2003
  • Ipriflavone (IP), a non-hormonal isoflavone derivative, has been shown to interfere with bone remodeling by inhibiting bone resorption and stimulating bone formation. IP consistently increased the amount of Ca incorporated into the cell layer by mesenchymal stem cells (MSCs). In this study, we developed the novel IP loaded poly(L-lactide-co-glycolide) (PLGA) scaffolds for the possibility of the application of the tissue engineered bone. IP/PLGA scaffo1ds were prepared by solvent casting/salt leaching method and were characterized by porosimeter, scanning electron microscopy, determination of residual salt amount, differential scanning calorimetry, and X-ray diffractometer, respectively. IP/PLGA scaffolds were implanted into the back of athymic nude mouse to observe the effect of IP on the osteoinduction compared with control PLGA scaffo1ds. Thin sections were cut from paraffin embedded tissues and histological sections were stained H&E, von Kossa, and immunohistochemical staining for Type I collagen and osteocalcin. It can be observed that the porosity was above 91.7% and the pore size was above 101 $\mu\textrm{m}$. Control scaffo1d and IP/PLGA scaffo1ds of 50% IP were implanted on the back of athymic nude mouse to observe the effect of IP on the induction of cells proliferation for 9 weeks. The evidence of calcification, osteoblast, and osteoid from the undifferentiated stem cells in the subcutaneous sites and other soft connective tissue sites having a preponderance of stem cells has been observed. From these results, it seems that IP plays an important role for bone induction in IP/PLCA scaffolds.

Solvent Filtration Performance of Thin Film Composite Membranes based on Polyethersulfone Support (폴리이터설폰 지지체를 활용한 박막복합막의 용매투과특성 연구)

  • Kim, SeungHwan;Kim, YooShin;Kim, DoYong;Kim, SooMin;Kim, Jeong F.
    • Membrane Journal
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    • v.29 no.6
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    • pp.348-354
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    • 2019
  • Recently, the application range of organic solvent nanofiltration (OSN) technology has been expanding, requiring membranes with better performance. In this work, thin film composite (TFC) OSN membrane was fabricated. First, ultrafiltration support membrane was prepared via nonsolvent-induced phase separation (NIPS) technique using polysulfone (PSf) and polyethersulfone (PES). Then, the effect of pore forming additives such as polyvinylpyrrolidone (PVP) and pluronic F-127 were employed to improve the membrane permeance. The well-known interfacial polymerization technique was employed using MPD-TMC chemistry to form a thin film on top of the fabricated support, and its solvent permeance and nanofiltration performance was characterized. It was found that polyethersulfone support exhibited more reliable performance compared to polysulfone, and PVP additive was more effective compared to Pluronic F-127. As for the oSN performance, polar aprotic solvents like acetonitrile show significantly higher flux (986.5 L·m-2·h-1·bar-1) compared to water and EtOH (9.5 L·m-2·h-1·bar-1).

Fabrication of PCL Scaffolds According to Various Pore Patterns Using Polymer Deposition System and Design of Experiments (폴리머 적층 시스템과 실험계획법을 이용한 다양한 공극 패턴에 따른 PCL 인공지지체의 제작 연구)

  • Sa, Min-Woo;Choi, Sun-Woong;Lee, Jae-Wook;Kim, Jong Young
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.41 no.7
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    • pp.645-653
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    • 2017
  • In bone tissue engineering, polycaprolactone (PCL) is one of the most widely used biomaterials in the manufacturing of scaffolds as a synthetic polymer having biodegradability and biocompatibility. The strut width in the fabrication of scaffolds is an important part of tissue regeneration in in-vitro and in-vivo experiments, because it affects not only the pore size but also the porosity. In this study, we used polymer deposition system (PDS) and design of experiments (DOE) to explore the optimal process conditions to achieve a systematic and efficient scaffold manufacturing process, using temperature, pressure, scan velocity, and nozzle tip height as the parameters for the experiments. The aim of this research was to fabricate a 3D PCL scaffold having a uniform strut width of $150{\mu}m$ using DOE; it was proved that the strut width was constant in all the experimental groups by fabricating the PCL scaffolds according to various pore patterns as well as one pore pattern.

Preparation of Superflux Nickel Capillary Support with 3D Macropore Channel Network For Gas Separation and Liquid Filtration Membranes (기체/액체 분리막을 위한 3차원 Macropore 채널을 갖는 Superflux 니켈 모세관 지지체의 제조)

  • Song, Ju-Seob;Cho, Churl-Hee
    • Membrane Journal
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    • v.28 no.3
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    • pp.214-219
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    • 2018
  • In the present study, superflux nickel capillary supports for gas and vapor separation membranes were prepared by a combined process of NIPS and sintering. Nickel capillary precursors were prepared by NIPS process from PSf-Ni-DMAC-PEG400 dope solution and was sintered at various temperatures in $H_2$ atmosphere to reliably produce Ni capillary support. The optimized Ni capillary support has an outer and inner diameters of 722 and $550{\mu}m$, and its thickness was $94{\mu}m$. It has 3-dimensional pore channel network and its porosity and mean pore diameter was 26% and $4{\mu}m$, respectively. Also, its mechanical strength was tested in tensile mode: its fracture load was 2.84 kgf and the fracture elongation was 13%. Finally, its single gas permeance was measured: He, $N_2$, $O_2$, and $CO_2$ permeance was 432,327, 281,119, 264,259, and 193,143 GPU, respectively. The superflux behavior could be explained from viscous flow through the macropores having a diameter of $4{\mu}m$ and narrow thickness. It could be concluded that the superflux behavior of the Ni capillary support was from the 3-D pore channel network and the small thickness.

Manufacture of Composite Electromagnetic Absorber using Natural Lacquer Binder (옻을 지지재로 이용한 복합형 전자파 흡수체의 제작)

  • 김동일;최동한;김수정;박우근;송재만;김민정
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.14 no.7
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    • pp.756-761
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    • 2003
  • The microwave absorption properties of silicone, chloride polyethylene(CPE), and natural lacquer which is newly suggested in this study as a binder for composite microwave absorber were investigated to develop a superior microwave absorber. MnZn ferrite composite microwave absorbers mixed with them were prepared and their absorption property was investigated. A MnZn ferrite microwave absorber mixed with natural lacquer showed an excellent microwave absorption property in expanded frequency band.

Preparation of Porous Silica Support and TiO2 Coating by Sol-Gel Method (다공성 실리카 지지체 제조 및 Sol-Gel법에 의한 TiO2코팅)

  • 한요섭;박재구
    • Journal of the Korean Ceramic Society
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    • v.41 no.7
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    • pp.548-554
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    • 2004
  • A sol-gel method was applied to coat TiO$_2$ on porous silica prepared using slurry foaming method from silica. from the results of XRD, SEM, and BET, the anatase phase was firstly observed at the coated supports with the heated of 50$0^{\circ}C$. The coated supports with the heated of $700^{\circ}C$ had the maximum anatase peak, and the particle size of coated TiO$_2$ was about 1 ${\mu}{\textrm}{m}$. Bending strength and gas permeability of the porous silica were measured for the feasibility as a catalytic supports. In case of the uncoated porous materials with the strength of 2.4 MPa, the strength increased to 3.9∼4.3 MPa after the coating process regardless of the heating temperature. On the other hand, the permeability of the uncoated porous materials decreased from 770${\times}$10$^{-13}$ $m^2$ to 363${\times}$10$^{-13}$ $m^2$ after the coating process, and it decreased with the increasing heating temperature.