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http://dx.doi.org/10.3795/KSME-A.2014.38.11.1273

Characteristic Analysis and Fabrication of Bioceramic Scaffold using Mixing Ratios of TCP/HA by Fused Deposition Modeling  

Sa, Min-Woo (Dept. of Mechanical Engineering, Andong Nat'l Univ.)
Kim, Jong Young (Dept. of Mechanical Engineering, Andong Nat'l Univ.)
Publication Information
Transactions of the Korean Society of Mechanical Engineers A / v.38, no.11, 2014 , pp. 1273-1281 More about this Journal
Abstract
Tissue engineering is an emerging research field that has the potential to restore, regenerate and repair damaged bone tissue and organs. Tricalcium phosphate and hydroxyapatite biomaterials-based calcium phosphate are excellent materials that have both osteoconduction and biocompatibility for bone tissue regeneration. In this study, solution structures were successfully fabricated using a fused deposition modeling system based on deposition and heating devices. The morphology characteristics of the bioceramic scaffolds sintered at a temperature of $1,300^{\circ}C$ were analyzed by scanning electron microscopy. The effects of various blended TCP/HA ratio on the microstructure and shrinkage were studied. The mechanical properties of the scaffolds were measured using a compression testing machine from stress-strain curves on the crosshead velocity of 1 mm/min. The fabricated scaffolds were evaluated by cell proliferation tests of MG-63 cells. The results of this study suggest that the blended TCP(75 wt%)/HA(25 wt%) scaffold is an appropriate scaffold for bone tissue regeneration.
Keywords
Fused Deposition Modeling; Tricalcium Phosphate; Hydroxyapatite; Scaffold;
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Times Cited By KSCI : 6  (Citation Analysis)
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