• Title/Summary/Keyword: 지방췌장

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Ultrasonic image assessment of the degree of pancreatic fat deposition (췌장 지방 침착 정도에 따른 초음파 영상 평가)

  • Park, Hye-in;Park, Seung-hun;Beak, Yun-seung;Lee, Seon-bin;Lee, Eun-sol;Heo, Yeong-dae;Cho, Jin-young;Ko, Seong-Jin
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2016.05a
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    • pp.490-492
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    • 2016
  • Pancreatic ultrasound imaging is used to diagnose pancreatic hyperplasia, pancreatic steatosis, pancreatic cancer and the like. If the diagnosis of pancreatic steatosis is pancreatic parenchyma echo shades splashes spleen than in the pancreas ultrasound it determines that the fat is deposited. And research on ultrasound imaging of pancreatic cancer but is actively conducted research studies on pancreatic steatosis is insufficient In addition, pancreatic steatosis is often an error in accordance with the diagnostic criteria are vague and subjective diagnosis of the artisan. This study was a quantitative analysis using the feature value extracting a feature of an image extracted by applying a parameter to the algorithm GLCM image of the normal and pancreatic fat. Setting a region of interest ($5{\times}5pixel$) in the mild 89 case, moderate 89 case, severe 89 case, total image 267 case using GLCM algorithm, and using the Autocorrelation, Sum average, Sum of squares, Sum varience 4 kinds parameter in each image It was analyzed.

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Analysis of the Relationship between Fatty Pancreas and Cardiovascular Disease in Abdominal Ultrasonography (복부초음파검사에서 지방췌장증과 심혈관계질환과의 연관성 분석)

  • Cho, Jin-young;Ye, Soo-young
    • Journal of the Korean Society of Radiology
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    • v.13 no.5
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    • pp.729-737
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    • 2019
  • Fatty pancreas is an abnormal process of lipid deposition in cells, resulting in increased fat tissue and obesity. The result is a risk factor for cardiovascular and metabolic diseases. The aim of this study was to evaluate the usefulness of pancreatic fat as a predictor of cardiovascular disease and metabolic syndrome in pancreatic ultrasonography. In 407 patients who underwent a comprehensive screening at the W Health Care Center in Busan from September 2. 2018 to December 31, 2018, the degree of fat deposition in the pancreas was evaluated as the degree of mild, moderate. Data on non-obstructive atherosclerosis, BMI, hyperlipidemia, hypertension, and diabetes were collected to assess the association of pancreatic fat deposition with cardiovascular disease and metabolic syndrome. In addition, we tried to analyze the correlation between liver dysfunction and thyroid dysfunction as the degree of fat pancreas increased. We examined the relationship between six parameters including atherosclerosis, BMI, hyperlipidemia, hypertension, diabetes, liver dysfunction, and thyroid dysfunction among patients with fatty pancreas. We concluded that the carotid intima-media thickness of atherosclerosis, which is a risk factor of cardiovascular disease, is most closely related to fatty pancreas.

The Study on Risk Factor of Metabolic Diseases in Pancreatic Steatosis (췌장지방증에서 대사성질환의 위험 요인에 관한 연구)

  • Cho, Jin-Young;Ye, Soo-Young;Kim, Dong-Hyun
    • Journal of radiological science and technology
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    • v.39 no.1
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    • pp.81-88
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    • 2016
  • The body of the fat tissue increased in obese represented by risk factors such as cardiovascular diseases, diabetes, metabolic disease and dyslipidemia. Such metabolic diseases and the like of the cardiovascular and cerebrovascular disease, hypertension, dyslipidemia, increase in the adipose tissue of the pancreas is known to be a risk factor of these diseases. Study on the diagnosis and treatment of pancreatic cancer was conducted actively, case studies on pancreatic steatosis is not much. In this study, divided into a control group diagnosed with pancreatic steatosis as a result of ultrasonography to evaluation the physical characteristics and serologic tests and blood pressure and arterial stiffness. The control group and the test pancreas steatosis age and waist circumference, body mass index, total cholesterol, HDL cholesterol, LDL cholesterol, and systolic and diastolic blood pressure, fasting blood glucose, arterial elasticity is higher in pancreatic steatosis. And the lower ankle brachial stenosis and HDL-cholesterol were lower than the normal control group, so the pancreatic steatosis harmful to blood vessels.(P <0.05). The difference between the control group and it was confirmed that the pancreatic jibanggun statistically significant. In conclusion, pancreatic steatosis at abdominal ultrasound can predict the risk of metabolic diseases, and there was a correlation with cardiovascular disease.

학술자료I- 고양이 외인성 췌장부전 Part 2(Feline Exocrine Pancreatic Insufficiency)

  • Lee, Jin-Su
    • Journal of the korean veterinary medical association
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    • v.47 no.12
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    • pp.1086-1090
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    • 2011
  • 외인성 췌장부전은 췌장에서 분비되는 소화효소의 부족한 합성 및 분비에 기인한다. 대부분의 개체에서 보이는 임상증상은 체중감소, 다량의 연변, 지방변이다. 혈청 고양이 유사트립신 면역활성 농도검사는 외인성 췌장부전 진단에 있어 매우 유용한 검사법이다. 외인성 췌장부전 환자의 치료는 췌장 소화효소의 공급이다. 대부분의 외인성 췌장부전 환자에서 심각한 혈청 코발라민의 감소와 동반되기 때문에 코발라민의 투여는 반드시 필요하다. 마지막으로 개에 비해 흔하게 확인되진 않지만, 만성적인 연변 및 체중감소를 보이는 환자에서는 진단에 있어 외인성 췌장부전에 대한 고려가 필요하다.

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Perilesional Steatosis in Ectopic Pancreas Mimicking Exogastric Mass : A Case Report (주변부 지방침윤으로 인해 외위장 종괴로 보이는 이소성 췌장: 증례 보고)

  • Nam, Mi Yeon;Kim, Mi Young;Kim, Yeo Ju;Suh, Chang Hae;Choi, Suk Jin;Cho, Jae Sung
    • Investigative Magnetic Resonance Imaging
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    • v.17 no.2
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    • pp.154-157
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    • 2013
  • We report an unusual case of ectopic pancreas that appeared on radiologic images as a lobulated, submucosal mass enclosed by fat component in the gastric lower body. Although, ectopic pancreas including fat component is extremely rare, in the setting of gastric submucosal mass with containing perilesional fat, these findings should be considered in ectopic pancreas as part of the differential diagnosis.

Novel circulatory connection from the acupoint Zhong Wan(CV12) to pancreas (중완혈에서 췌장으로 이어지는 새로운 순환적 연결)

  • Kim, Min-Soo;Sung, Baeck-Kyoung;Ogay, Vyacheslav;Choi, Chun-Ju;Kim, Min-Su;Kang, Dae-In;Soh, Kwang-Sup
    • Journal of Pharmacopuncture
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    • v.11 no.1
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    • pp.13-19
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    • 2008
  • Objectives : Demonstrating a novel circulatory path from the acupoint(CV12) to the pancreas. Method : Alcian blue(1% solution, $20{\mu}l$, pH 7.4) was injected into the acupoint(CV12). Two hours later the surfaces of internal organs were observed by using a stereomicroscope. Results : Alcian blue arrived and colored the omental fat band(OFB) on the pancreas. The OFB connected the head and tail of the pancreas, the pancreas and the spleen, and the pancreas and the stomach. Conclusion : The existence of a novel circulatory path from the acupoint CV12 to the pancreas and its OFB was demonstrated.

A Study on the Activation Conditions of Pancreatic Enzymes (판크레아틴 소화효소의 활성화 조건 연구)

  • Kim, Dong-Chung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.1
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    • pp.276-280
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    • 2011
  • This study investigated the activation conditions of pancreatic enzymes from porcine pancreas. Duodenum induced the activation of pancreatic protease and lipase in pancreas. When 10% duodenum was added to pancreatic juice and the mixture was incubated at $30^{\circ}C$ for 90 min or at $25^{\circ}C$ for 4 hrs, the activities of pancreatic protese and lipase reached the peak. When the pancreatin was prepared by sequential process of enzymatic activation at $25^{\circ}C$ for 4 hrs, centrifugation, acetone precipitation and freeze-drying, the specific activities of pancreatic protease, lipase and amylase were 136, 116 and 400 U/mg-protein, respectively. The protease, lipase and amylase activities of the prepared pancreatin were 5.4, 58.0 and 16.0 times higher than those of USP standard, respectively.

Development of Egg Yolk Antibody Specific to the Pancreatic Lipase Domain for Anti-Obesity (비만 억제를 위한 췌장 리파아제 도메인에 대한 특이 난황항체의 개발)

  • Woo, Seung-Eun;Kwon, Jin-Hyuk;Yang, Si-Yong;Park, Hyun-Ju;Kim, Hyung-Kwoun
    • Microbiology and Biotechnology Letters
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    • v.36 no.4
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    • pp.299-306
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    • 2008
  • Human pancreatic lipase is a digestive enzyme which is synthesized in pancreas, secreted into small intestine, and there hydrolyze the fat in food. Pancreatic lipase protein composes of catalytic domain and colipase-binding domain. In this research, the gene segments corresponding to total protein, catalytic domain, and co lipase-binding domain were cloned by PCR method, inserted into an expression vector, and then used to transform Escherichia coli BL21 (DE3). The recombinant proteins produced were purified and injected intramuscularly three times into laying hens. The egg yolk antibodies (IgY) were obtained from the egg yolks and tested for their antibody titer. Among three IgY, the IgY against colipase-binding domain showed the highest antibody titer. All three IgY had inhibitory effects on the porcine pancreatic lipase. Among them, the IgY against colipase-binding domain showed the highest inhibition effects. The fat diet with corn oil and IgY was administrated to the experimental rats and their blood compositions were examined with time course. The triglyceride concentration of treated rats was decrease meaningfully when compared with those of control rats. This suggested that the IgY against colipase-binding domain antigen inhibited pancreatic lipase in vivo.

The assessment of fat absorption rate and Ca bioavailability in rats fed high sn-2 palmitate formula diet (sn-2 팔미틴산 강화유지를 섭취한 흰쥐의 지방흡수율 및 칼슘 체내이용성 측정)

  • 강은영;이연숙
    • Proceedings of the KSCN Conference
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    • 2003.05a
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    • pp.136-136
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    • 2003
  • 중성지방(TG)은 모유와 조제분유의 주요에너지원이며 전체에너지의 50%까지 제공한다. 그러나, 일반 조제분유와 모유의 TG구조는 상당히 다르며, 이러한 구조적 차이로 인해 지방 및 칼슘흡수에 차이가 생긴다. 즉, 모유지방산의 1/4정도를 구성하는 팔미틴산은 이것의 70%정도가 glycerol 의 두 번째 탄소에 결합되어 있는 sn-2(middle)position으로 되어 있으며, 이러한 위치의 팔미틴산은 일반적으로 췌장지방분해 효소에 의해 분해되지 않고 2-monoglyceride로 존재한다. (중략)

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