• Title/Summary/Keyword: 지방대학교

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The Study of Lipid Proton Composition Change in a Rat Model of High Fat Diet Induced Fatty Liver by Magnetic Resonance Spectroscopy Analysis (고지방식이 유도성 지방간 쥐 모델에서 간의 자기공명분광 분석을 이용한 지질 양성자 조성 변화 연구)

  • Kim, Sang-Hyeok;Yu, Seung-Man
    • Journal of radiological science and technology
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    • v.44 no.4
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    • pp.315-325
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    • 2021
  • The purpose of this study is to investigate the changes in lipid proton (LP) composition according to the induced obese fatty liver and to use it as basic data for treatment and diagnosis of fatty liver in the future. The phantom study was conducted to identify differences between STEAM and PRESS Pulse sequences in LP concentration. A high-fat diet (60%) was administered to eight Sprague-Dawley rats to induce obesity and fatty liver disease. Baseline magnetic resonance imaging /spectroscopy data were obtained prior to the introduction of high-fat diet, and data acquisition experiments were performed after eight weeks using procedures identical to those used for baseline studies. The six lipid proton metabolites were calculated using LCModel software. The correlation between the fat percentage and each LP, revealed that the methylene protons at 1.3 ppm showed the highest positive correlation. The α-methylene protons to carboxyl and diallylic protons showed negative correlation with fat percentage. The methylene proton showed the highest increase in the LP; however, it constituted only 71.86% of the total LP concentration. The methylene proton plays a leading role in fat accumulation in liver parenchyma.

A Study on Records Disclosure Management of Local Governments in Busan (부산 지방자치단체의 기록물 공개관리에 관한 연구)

  • Yoon, YeonHwa;Lee, Eun-Ju
    • Journal of Korean Society of Archives and Records Management
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    • v.21 no.1
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    • pp.57-73
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    • 2021
  • This study seeks to grasp the current status of and suggest improvements on records disclosure management. Data were collected through a literature review, surveys, and in-depth interviews with 7 record managers and 40 office staff in local governments. Existing records disclosures were also used as references for the discussion. With this, self-reliance efforts within local governments and active roles in central records management institutions were proposed.

Correlation of Body Mass Index, Body Fat Distribution, Aminotranferases and Computed Tomography in Obese Children with Fatty Liver (비만을 동반한 소아 지방간 환아에서 체질량 지수, 체지방 분포, 간 효소치 및 복부 CT 소견과의 상관관계에 대한 연구)

  • Park, So Eun;Yang, Hye Ran;Chang, Ju Young;Ko, Jae Sung;Seo, Jeong Kee;Lee, Whal;Kim, Woo Sun
    • Clinical and Experimental Pediatrics
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    • v.48 no.3
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    • pp.276-283
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    • 2005
  • Purpose : Visceral fat accumulation plays a major role in metabolic complications of obesity. It is known that nonalcoholic fatty liver in obese adults is associated with visceral fat accumulation. Body mass index(BMI) is used as the index of obesity in children. The aim of this study is to evaluate the correlation of BMI and visceral adipose tissue(VAT), and the correlation of BMI, body fat distribution, aminotransferases, and severity of fatty liver. Methods : Twenty three obese children with fatty liver diagnosed by non-contrast abdominal computed tomography(CT) were included in this study. Data on BMI, aminotransferase levels were collected from clinical records. Visceral adipose area was evaluated with CT. Results : BMI had a singnificant correlation with VAT(r=0.51719, P=0.0115). The severity of fatty liver had no significant correlations with BMI(r=-0.11938, P=0.5876), VAT(r=-0.31234, P=0.1468), aspartate aminotransferase(AST)(r=0.12729, P=0.5628) or alanine aminotransferase(ALT)(r=-0.00179, P=0.9935). Conclusion : BMI in obese children was correlated with VAT. But the severity of fatty liver cannot be assessed by BMI, VAT or aminotransferase levels.

Antioxidant Activity and Fatty Acid Aomposition of Beach Rose (Rosa rugosa) Fruit and Seed from Various Ripening Stages (해당화 열매 과육과 종실의 숙기별 항산화능 및 지방산 조성)

  • Chae, Sung Hun;Song, Hun Jong;Lee, Young Sang;Han, Tae-Ho;Ku, Kang-Mo
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2019.10a
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    • pp.69-69
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    • 2019
  • 해당화 열매를 숙기 별로 과육의 항산화물질 함량과 씨앗의 지방산 함량을 측정하여 평가하였다. 과육의 1,1-diphenyl-2-picrylhydrazyl (DPPH) 항산화능을 갈산 환산농도로 나타내면 미성숙 과육은 $4.36{\pm}0.03mg/g$, 성숙 초기 과육은 $4.54{\pm}0.37mg/g$, 성숙 중기 과육에는 $4.78{\pm}0.21mg/g$, 성숙 후기에는 $4.30{\pm}0.22mg/g$ 범위로 항산화능을 보여주었다. 항산화능력은 성숙중기에서 높은 함량을 보여주었고 성숙함에 따라 감소함을 보여주었다. 미성숙, 성숙 초기는 유의한 걸로 나오지만 성숙 중기와 성숙 후기은 다른 성숙도와 유의하지 않았다. 총 페놀 함량의 미성숙 과육은 $1.60{\pm}0.03mg/g$, 성숙 초기 과육은 $1.80{\pm}0.08mg/g$, 성숙 중기 과육에는 $2.03{\pm}0.67mg/g$, 성숙 후기에는 $1.53{\pm}0.07mg/g$ 범위로 폴리페놀이 존재하였다. 성숙 초기에 제일 높은 항산화능력과 폴리페놀 함량을 보여주고 있으며 성숙할수록 항산화능력과 총 페놀 함량이 떨어지는 것을 알 수 있다. 씨앗의 지방산 함량은 리올레산, 리놀렌산, 올레산, 팔미트산 순으로 많았다. 리올레산은 미성숙 씨앗은 전체 함량 중 56.46%, 초기 과육 씨앗에는 54.26%, 중기 과육 씨앗에는 51.67%, 후기 씨앗에는 50.75%의 함량을 가지고 있다. 리올렌산은 미성숙 씨앗은 전체 함량 중 18.80, 초기 과육 씨앗에는 17.96%, 중기 과육 씨앗에는 18.90%, 후기 씨앗에는 21.42%의 함량을 가지고 있다. 올레산은 미성숙 씨앗은 전체 함량 중 13.54%, 초기 과육 씨앗에는 20.78%, 중기 과육 씨앗에는 22.44%, 후기 씨앗에는 20.81%의 함량을 가지고 있다. 팔미트산은 미성숙 씨앗은 전체 함량 중 6.80%, 초기 과육 씨앗에는 3.40%, 중기 과육 씨앗에는 3.37%, 후기 씨앗에는 3.32%의 함량을 가지고 있다. 리올레산은 미성숙 시기에 가장 많았고 리올렌산은 후기에 올레산은 중기에, 팔미트산은 초기에 많았다.

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Analysis of the seed metabolite profiles and antioxidant activity of perilla varieties (대사체분석 기술을 이용한 들깨 종자의 품질 특성 및 항산화 효과)

  • Gu, Suyeon;Son, Yejin;Park, Ji Yeong;Choi, Sung-Gil;Lee, Myoung Hee;Kim, Hyun-Jin
    • Korean Journal of Food Science and Technology
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    • v.51 no.3
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    • pp.193-199
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    • 2019
  • Perilla seed oil is considered to be a rich source of omega-3 fatty acids and phenolic compounds, which have various health benefits. To improve its oil content and nutritional quality, 29 varieties of perilla have been bred, but their nutritional qualities, including the fatty acid and phenolic compound contents, have not been investigated. Therefore, in this study, the seed metabolite profiles, including the fatty acids, of these 29 perilla varieties were analyzed. Palmitic acid, stearic acid, linoleic acid, linolenic acid, rosmarinyl glucoside, and rosmarinic acid were identified as the major metabolites of perilla. The fatty acid contents were higher in the Okdong, Deulsaem, Daesil, Joim, Yeupsil, Danjo, and Joongmo5103 varieties (in order). However, the total phenolic compounds and antioxidative activities of Okdong and Deulsaem were relatively low, whereas the fatty acid and total phenol contents of Joim, Yeupsil, and Danjo were relatively high. These results may be useful for comparing the nutritional quality of the 29 perilla varieties.

Expression of Antisense Mouse Obese Gene in Transgenic Mice (형질전환 생쥐에서 Antisense 비만유전자의 발현)

  • Kwon, B.S.;Hong, K.H.;Jahng, J.W.;Lee, H.T.;Chung, K.S.
    • Korean Journal of Animal Reproduction
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    • v.24 no.4
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    • pp.419-428
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    • 2000
  • Leptin, the product of obese (ob) gene, is an adipocyte-derived satiety factor that plays a major role in the regulation of food intake, energy homeostasis, body weight, reproductive physiology and neuropeptide secretion. The present study was designed to generate transgenic mice expressing antisense mouse ob (mob) gene. Total RNA was extracted from the adipose tissues of mouse, then reverse transcription was performed. The 303 and 635 bp fragments of anti I and II cDNAs were amplified from mob cDNAs by PCR. The two mob cDNAs were reversely ligated into between adipose tissue specific aP2 promote and SV40 poly(A) site. Transgenic mice carrying two different kinds of antisense mob transgenes were generated by DNA microinjection into pronucleus. Total 14 transgenic mice were born, and the 4 and 5 founder lines of the transgenic mice with anti I and II transgenes were respectively established. Antisense mRNA expression was detected in transgenic F$_1$ mice by RT-PCR analysis. This result suggests that the transgenic mice expressing antisense mob mRNA may be useful as an animal disease model to be obesity caused by decreased amount of leptin secretion.

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Records Culture and Local autonomy (기록문화와 지방자치)

  • Lee, Young-Hak
    • The Korean Journal of Archival Studies
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    • no.26
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    • pp.63-93
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    • 2010
  • This document illustrates the culture of archives should be improved to get better in local autonomy. In 1994, the municipal elections were held to perform autonomous activities in Korea. It has been sixteen years, since the first municipal election had been held. The local autonomy can be accomplished well, based on the economic independence from the central government and growing awareness of locals. Not only that, if local records were well archived and suitably used, autonomy could be more active. However, since the independence from Japan in 1945, records of the self-government has not been archived well. Not only archives of local government have not been established, but also organization, budget and professional staff have not been arranged well. This brought about local records administration's inactive performance. As a result, numerous number of meaningful records are lost and people are difficult to make out the local administration policy. If the records of local government preserved well, administrative efficiency, responsibility, transparency can be realized in better way. When local officials' work experiences and achievements were on record and referred to a successor of officials properly, administrative efficiency would be highly promoted. In addition, with the well-preserved work records, people are able to see where the responsibility lies. A local autonomous entity might be able to obtain administrative transparency by showing administrative processes and results to locals to the public. In this manner, the premise to archive the records of local autonomous entity is to establish a department which can archive local records and the disposition of professional archivists. According to "the law on public archives management", the governor of a province should discuss with a minister of administration to set up plans for archives' establishment and management. In this way, local archives administration would work well, when not only the department of local records administration is established, but also the department of local archives places local records under their control at the same time. Moreover, based on active records movement, municipal officials and locals would realize the importance of local record and examine local records administration systems. Not only that, when local records are shown to public and utilized properly, the local autonomy would improve a lot.

Overcoming the Local Industrial Complex Crisis in the Era of Digital Transformation (디지털전환 시대 지방산업단지 위기 극복방안)

  • Seung-Hee Lee
    • Journal of Digital Convergence
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    • v.21 no.1
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    • pp.15-18
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    • 2023
  • The purpose of this study is to suggest ways to overcome the crisis of regional industrial complexes by examining the changes that the digital transformation era will bring and the crisis situation of regional industrial complexes. To this end, first, we examine the changes brought about by the digital transformation era from various angles in the fields of industrial sites, industrial complexes, policy areas, and changes in working methods, and identify the problems and crises of local industrial complexes from various aspects. According to the problems and crises of these existing local industrial complexes, plans and various policy tasks were presented for local industrial complexes to overcome the crisis using digital technology. As a result of this study, important policy directions and alternatives for overcoming the crisis of local industrial complexes in stagnation are presented at the government level, and plans for strengthening self-sustainability to overcome the crisis at the corporate level and digital transformation for future local industrial complexes It was possible to look at the direction and tasks of the project from various aspects.

Exploring Place Identity and Sustainable Residency of Youth Migrating to Local Areas (청년들의 지방이주와 정주지속을 위한 장소정체성 연구)

  • Lee, Chang-Hyun;Park, Ji-Young
    • Journal of the Korean Institute of Landscape Architecture
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    • v.51 no.3
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    • pp.139-152
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    • 2023
  • Recently, there has been an increasing interest in the migration of young people to local areas. These young people are discovering and reinterpreting local resources to open local businesses while generating new value in local activities and businesses. This study was initiated with the recognition that fundamental solutions are needed for these young people to settle and sustain residence in the local area. Edward Relph stated that 'place' is a fundamental attribute that influences human existence in the world and is the source of stability and identity formation for individuals. This is deeply related to the psychology of young people who have migrated to local areas. These young people accept the unfamiliar 'space' as a 'place' to form stability and personal identity. Therefore, this study utilized PhotoVoice methodology to examine the process and key factors of place identity formation among migrant youths. As a result, the study identified factors that enable young people to settle in local areas and sustain residence while recognizing elements the local government should focus on to support and address the influx of young people. The results of this study can serve as a foundation for addressing the declining population in local areas through the formation of a relationship population and spur the inflow of young people to local cities in the future.