• Journal of Korean Academy of Nursing
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• v.28 no.4
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• pp.893-907
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• 1998

The purpose of this study was to determine the effect of regular exercise during dexamethasone injection on the body weight, weight of hindlimb muslces, myofibrillar protein content and glutamine synthetase activity. 180-200g female Wistar rats were divided into four groups : control, exercise, dexamethasone injection (dexa), and exercise during dexamethasone injection(D+E) group. The dexa group received daily subcutaneous injection of dexamethasone at a dose of 4mg/kg body weight for 7 days. The exercise group ran on a treadmill for 60min/day(20minutes every 4 hours) at 10m/min and a 10$^{\circ}$grade. The control group received daily subcutaneous injection of normal saline at a dose of 4mg/kg body weight for 7 days. The D+E group ran on a treadmill for 60min/day(20minutes every 4 hours) at 10m/min and a 10$^{\circ}$ grade during dexamethasone injection. Body weight of the control group increased significantly from days of experiment, that of the dexa group decreased significantly from day 4 of the experiment resulting in a 82.4% decrease compared to the first day of the experiment. Body weight of the D+E group decreased significantly from day 5 of experiment resulting in a 81.77% decrease comprared to the first day of the experiment. Body weights, muscle weight and myofibrillar protein content of the plantaris and gastrocnemius decreased significantly and muscle weight of the soleus tended to decrease with dexamethasone injection. Glutamine synthetase activity of the hindlimb muscles increased significantly with the dexamethasone injection. The relative weight of the soleus was comparable to the control group and that of plantaris decreased significantly and that of gastrocnemius tended to decrease compared to that of the control in the dexa group. Body weight and muscle weight of the plantaris and gastrocnemius of the excrcise group were comparable to the control group, and the muscle weight of soleus showed a tendencey to increase. The relative weight of the soleus increased significantly and that of the plantaris and gastrocnemius were comparable to the control in the exercise group. Myofibrillar protein content of the soleus and plantaris increased significantly and there was no change of GS activity of the hindlimb muscles compared to the control in the exercise group. Body weight of the D+E group was comparable to the dexa group, muscle weight of the plantaris increased significantly and that of the soleus and gastrocnemius showed a tendency to increase. The relative weight of the hindlimb muscles increased significantly. Myofibrillar protein content of the soleus and plantaris increased significantly and that of the gastrocnemius tended to increase compared to the dexa group. Body weight and muscle weight of the plantaris and gastrocnemius of the D+E group did not recover to that of the control group. Muscle weight of the soleus recovered to that of the control group. The relative weight and of myofibrillar protein content of the hindlimb muscles recovered to that of the control group. From these results, it is suggested that regular exercise during dexamethasone injection might attenuate the muscle atrophy of the hindlimb muscles.

• Research in Community and Public Health Nursing
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• v.8 no.1
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• pp.31-44
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• 1997

The purpose of this study was to measure and determine the relationship of femoral neck and lumbar bone mineral density with their and related factors. It were measured and determined the relationships among bone mineral density, bone mineral content in the lumbar and femoral neck, muscle strength (arm, back, leg), muscle endurance, instrumental activity of daily living (IADL), quality of life, cognitive perceptual variables(self efficacy, perceived health status), age, age at menopausal period. The twenty five subjects participating in this study consisted of twelve males and thirteen females at a C-institution in Chung Buk province. The mean age of subjects was 73.64 years. The data was collected from August, 1993 to September, 1993. The data was analyzed with $x^2-test$, t-test, Correlation, multiple regression using a SPSS pc+ program. 1. The mean femoral neck bone mineral density was $0.636g/cm^2$, 66.7% of young bone mineral density, the mean lumbar($L_2-L_4$) bone mineral density was $0.807g/cm^2$, 79.86% of young bone mineral density. The mean fermoral neck bone mineral content was 2.906g and the mean lumbar bone mineral content was 36.898g. 2. The mean muscle strength was 17.14kg(grip strength), 32.05kg(back lift strength), 17.14kg (leg lift strength) and the mean muscle endurance was 9.92times. 3. Men showed a significantly higher score (p<0.01) in muscle strength and muscle endurance than women, as well as a significantly higher score on self efficacy and perceived health status(p<0.05). 4. The femur neck bone mineral density had a significant correlation(p<0.0l) with leg lift strength, back lift strength, and their was a significant correlations (p<0.05) with arm strength and muscle endurance. Lumbar ($L_2-L_2$) bone mineral density had a significant correlation(p<0.05) with muscle endurance, grip strength and IADL. 5. With the multiple regression analysis the most significant predictor for lumbar bone mineral density were IADL, the most significant predictor for femoral neck bone mineral density was leg strength. This study concluded: As the mean bone mineral density and bone mineral content were low, the aged showed osteopenia. Bone mineral density, muscle strength and IADL were correlated. The aged could pro mote muscle strength, bone mineral density and IADL through Leg Press exercise which was safe and efficient for the aged. This Leg Press exercise contributed to prevention of osteoporosis and promoted the health of the aged.

• Journal of the Korea Convergence Society
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• v.10 no.12
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• pp.387-397
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• 2019

The purpose of this study is to analyze the relationship between health related physical fitness, cognitive function, depression and quality of life variables of elderly people in a comprehensive way based on quantitative evaluation. The subjects of this study were 385 people who voluntarily participated in the elderly welfare center in Gyeonggi and Seoul the elderly people. As for the data collection methods, were measured the characteristics, depression and quality of life, cognitive function questionnaires along with measures of lower and upper body strength, dynamic equilibrium and agility, total endurance and grip strength. As a result, the first was a statistically significant correlation between integrated health of the elderly, cognitive function, quality of life and depression. Second, the analysis of cognitive function, elderly integrated health, quality of life, and depression revealed statistical significance among all variables. Third, there was the partial intervention effect of function in the quality of life and depression of the elderly.

• Journal of the Korean Society of Food Science and Nutrition
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• v.42 no.10
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• pp.1608-1617
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• 2013

This study is performed to evaluate the effectiveness of a weight management program for overweight and obesity office workers; comparing their changes in the anthropometry, biochemistry, nutrient intakes, and exercise performance before and after the obesity management program. This program was performed on 39 workers, who are overweight or obese, over BMI 23 for 6 months in Jeollabuk-do public institution. As the results of this study suggests, triceps thickness (TT) of male subjects was significantly decreased (P<0.05). Waist circumference (WC), and hip circumference (HC) of the total subjects were significantly decreased after the weight management program (P<0.05). The biochemical result of the Total cholesterol (TC) (P<0.05) and LDL cholesterol (LDL-C) (P<0.01) was significantly decreased in male subjects. The results of abdominal computed tomography (CT) also showed that subcutaneous fat area (SFA) of male subjects was significantly decreased after the weight management program (P<0.01). The nutrient intake's results of female subjects, who took Fe, Vit B2, and niacin, were increased significantly after the weight management program (P<0.05). The nutrition knowledge score of male subjects was significantly increased (P<0.05), and a muscular endurance of the physical test was significantly increased after the obesity management program (P<0.01). At the work place, workers need a systemic health and obesity management program to improve their work efficiency and quality of life. After this study, the program should be developed and supported continuously to maintain positive results from this study.

• Journal of Life Science
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• v.27 no.3
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• pp.361-369
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• 2017

Mitochondrial homeostasis is tightly regulated by two major processes: mitochondrial biogenesis and mitochondrial degradation by autophagy (mitophagy). Research in mitochondrial biogenesis in skeletal muscle in response to endurance exercise training has been well established, while the mechanisms regulating mitophagy and the relationship between mitochondrial biogenesis and degradation following endurance exercise training are not yet well defined. Studies have demonstrated that endurance exercise training increases the expression levels of mitochondrial biogenesis-, dynamics-, mitophagy-related genes in skeletal muscle. However, the increased levels of mitochondrial biogenesis marker proteins such as Cox IV and citrate synthase, by endurance exercise training were abolished when autophagy/mitophagy was inhibited in skeletal muscle. This suggests that both autophagy/mitophagy plays an important role in mitochondrial biogenesis/homeostasis and the coordination between the opposing processes may be important for skeletal muscle adaptation to endurance exercise training to improve metabolic function and endurance exercise performance. It is considered that endurance exercise training regulates each of these processes, mitochondrial biogenesis, fusion and fission events and autophagy/mitophagy, ensuring a relatively constant mitochondrial population. Exercise training may also have contributed to mitochondrial quality control which replaces old and/or unhealthy mitochondria with new and/or healthy ones in skeletal muscle. In this review paper, the molecular mechanisms regulating mitochondrial biogenesis and mitophagy and the coordination between the opposing processes is involved in the cellular adaptation to endurance exercise training in skeletal muscle will be discussed.

• Journal of Life Science
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• v.22 no.5
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• pp.665-670
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• 2012

This study investigated the effect of endurance exercises on blood pressure, angiogenesis, and the vascular endothelial growth factor (VEGF) expression in the skeletal muscle of spontaneously hypertensive rats (SHR). Five week old SHRs and Wistar-Kyoto rats (WKY) were randomly divided into 3 groups: Wistar-Kyoto rats (WKY, n=9), SHR control (SHR-C, n=9), and SHR endurance exercise training (SHR-E, n=9). Endurance exercise training was performed on a treadmill (12-20 m/min, 0% grade, 60 min/day, 5 days/week, 16 weeks). Systolic blood pressure was monitored with the tail-cuff method. The expression of VEGF protein and capillary density were identified using western blotting and H&E staining in the soleus muscle, respectively. Systolic blood pressure was reduced by endurance exercise in SHR ($p$ <0.05). The capillary density of skeletal muscles in SHR-C was lower than in WKY ($p$ <0.05), but it was recovered by endurance exercise training (SHR-E) compared to SHR-C ($p$ <0.05), and VEGF protein was also increased by endurance exercise training compared to SHR-C ($p$ <0.05). These data suggest that the enhancement of capillary density via an increase of VEGF expression in skeletal muscles by endurance exercise training could be an important factor to inhibit blood pressure elevation in SHR.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.12 no.1
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• pp.53-62
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• 2018

In this study, we developed a smart 1RM system for national health management and physical fitness, which enables quantitative 1RM measurement in various types of exercise using digital pulley technology, and to test the effect on training by using it. We developed the smart 1RM system, which is composed of portable muscle strength measuring device, Bluetooth communication based mobile phone data transmission and circuit diagram, and height adjustable system body. We recruited the 30 participants with 20th aged and divided into training and non-performing groups with 15 participants randomly. The participants performed 5 sets of elbow, lumbar, knee extension / flexion 10 times using smart 1RM system and the experimental period was 3 days a week for a total of 8 weeks. The experimental results showed that the maximum strength of the elbow, lumbar, and knee joints was significantly improved before and after maximal muscle strength training in the training group. Oxygen intakes during 1RM exercise mode showed 10.91% than endurance. To verify the validity of the smart 1RM maximal strength data, the reliability was 0.895 (* p <0.00). This study can be applied to the early rehabilitation treatment of the elderly and rehabilitation patients more quantitatively using the national health care.

• The Korean Journal of Food And Nutrition
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• v.19 no.2
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• pp.169-175
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• 2006

A unicellular algae, Chlorella vulgaris(CV), was used as a biological response modifier. The effect of CV on forced swimming test and blood biochemical parameters related to fatigue was investigated. Blood urea nitrogen(BUN); creatine kinase(CK); lactic dehydrogenase(LDH); glucose(Glc); total protein(TP); and albumin were determined. CV was orally administered to mice in the range of 0.05 to 0.15 g/kg/day. A forced swimming test results on 3 and 7 day after administration of CV, showed that immobility time was decreased in the CV-administered group(0.15 g/kg). In addition, the contents of BUN in the blood serum were decreased in CV-fed group. The contents of CK and LDH were tended to decrease, but not statistically significant. The plasma Glc level was increased in CV-fed groups(0.05 and 0.1 g/kg) compared to control group. It had no effect on the elevation of TP and albumin level. The results indicate that CV could improve physical stamina.

• 대한공업교육학회지
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• v.33 no.2
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• pp.44-71
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• 2008

This paper was intended to investigate employment conditions and career planning of ex-participants of the customized training program(CTP) in Technical High Schools for the specific Small and Medium Business through questionnaires. Results of the research were: 1. The average ex-participant of CTP was employed in small size company with 50 employees, earned 1~1.2 Million Won monthly, worked about 50 hours per week. 2. They were earnestly considering and worried about their career. They had their career goals : Engineer in production and manufacturing, CEO of a company, Design engineer. 3. They were not able to invest enough time and energy in developing their capabilities and skills. 4. There were feelings of respondents, which the main barriers of their career achievement were : (1) their deficiency of personal competencies and endurance. (2) not time enough to learn (3) the fallacy of organizational support and atmosphere.

• Journal of Digital Convergence
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• v.14 no.4
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• pp.471-478
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• 2016

The purpose of this study is to analyse the effect of 12-weeks of combined training on body composition and basic physical strength of obese female college students. The research object was composed of 12 obese female college students of D University, who learned the purpose of this research enough and wrote the consent form of voluntary participation, who have no medical history and currently no special disease, and no experience in regular exercise. They underwent body composition inspection, left right grasping power which is the basic physical strength, back muscle strength, flexibility, rapidity, muscle endurance, and the researcher performed descriptive statistics to calculate the average standard deviation, and analyzed to verify difference between groups by using paired t-test. With statistical significance level p<.05, the results are as follows. Obese female college students showed meaningful differences in weight, skeletal muscles, body fat volume and left right grasping power, back muscle strength, rapidity(p<.05) - flexibility and muscle endurance(p>.05).