Antifatigue Effect of Chlorella vulgaris in Mice
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An Hyo-Jin
(College of Oriental Medicine, Institute of Oriental Medicine, Kyung Hee University)
Seo Sang-Wan (Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University) Sim Kyung-Sik (Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University) Kim Jung-Suk (College of Oriental Medicine, Institute of Oriental Medicine, Kyung Hee University) Kim Eun-Hee (College of Oriental Medicine, Institute of Oriental Medicine, Kyung Hee University) Lee Mi-Ok (Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University) Park Hyeung-Suk (Daesang Corp. WellLife R&D Center) Han Jae-Gab (Daesang Corp. WellLife R&D Center) Lee Eun-Hee (Division of Beauty Arts, Jeonbuk Science College) Um Jae-Young (College of Oriental Medicine, Institute of Oriental Medicine, Kyung Hee University) Hong Seung-Heon (Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University) Kim Hyung-Min (College of Oriental Medicine, Institute of Oriental Medicine, Kyung Hee University) |
1 | Merchant, RE, Carmack, CA and Wise, CM. Nutritional supplementation with Chlorella pyrenoidosa for patients with fibromyalgia syndrome: a pilot study. Phytother. Res. 14:167-173. 2000 DOI ScienceOn |
2 | Porsolt, RD, Bertin, A and Jalfre, M. Behavioral despair in mice: a primary screening test for antidepressants. Arch. Int. Pharmacodyn. Ther. 229:327-336. 1977 |
3 | Ozturk, N, Baser, KH, Aydin, S, Ozturk, Y and Calis, I. Effects of Gentiana lutea ssp. symphyandra on the central nervous system in mice. Phytother. Res. 16: 627-631. 2002 DOI ScienceOn |
4 | Shu, J, Stevenson, JR and Zhou, X. Modulation of cellular immune responses by cold water swim stress in the rat. Dev. Comp. Immunol. 17:357-371. 1993 DOI ScienceOn |
5 | Hasegawa, T, Ito, K, Ueno, S, Kumamoto, S, Ando, Y, Yamada, A, Nomoto, K and Yasunobu, Y. Oral administration of hot water extracts of Chlorella vulgaris reduces IgE production against milk casein in mice. Int. J. Immunopharmacol. 21:311-323. 1999 DOI ScienceOn |
6 | Burr, JR, Reinhart, GA, Swenson, RA, Swaim, SE, Vaughn, DM and Bradley, DM. Serum biochemical values in sled dogs before and after competing in long-distance races. J. Am. Vet. Med. Assoc. 211: 175-179. 1997 |
7 | Mashiko, T, Umeda, T, Nakaji, S and Sugawara, K. Effects of exercise on the physical condition of college rugby players during summer training camp. Br. J. Sports Med. 38:186-190. 2004 DOI |
8 | Miyazawa, Y, Murayama, T, Ooya, N, Wang, LF, Tung, YC and Yamaguchi, N. Immunomodulation by a unicellular green algae (Chlorella pyrenoidosa) in tumor-bearing mice. J. Ethnopharmacol. 24:135-146. 1988 DOI ScienceOn |
9 | Merchant, RE and Andre, CA. A review of recent clinical trials of the nutritional supplement Chlorella pyrenoidosa in the treatment of fibromyalgia, hypertension, and ulcerative colitis. Altern. Ther. Health Med. 7:79-91. 2001 |
10 | Borsini, F, Cesana, R, Vidi, A and Mennini, T. Evidence that imipramine activates 5-HT1C receptor function. Eur. J. Pharmacol. 203:359-363. 1991 DOI ScienceOn |
11 | Kim, KM, Yu, KW, Kang, DH and Suh, HJ. Anti-stress and anti-fatigue effect of fermented rice bran. Phytother. Res. 16:700-702. 2002 DOI ScienceOn |
12 | Halperin, SA, Smith, B, Nolan, C, Shay, J and Kralovec, J. Safety and immunoenhancing effect of a Chlorella-derived dietary supplement in healthy adults undergoing influenza vaccination: randomized, double-blind, placebo-controlled trial. Cmaj. 169: 111-117. 2003 |
13 | Waldrop, DL, Ciraulo, TP, Milner, D, Gregori, AS, Kendrick, CM, Richart, RA, Maxwell, DE and Barker, A. comparison of continuous renal replacement therapy to intermittent dialysis in the management of renal insufficiency in the acutely III surgical patient. Am. Surg. 71: 36-39. 2005 |
14 | Mague, SD, Pliakas, AM, Todtenkopf, MS, Tomasiewicz, HC, Zhang, Y, Stevens, WC, Jr., Jones, RM, Portoghese, PS and Carlezon, WA, Jr. Antidepressant-like effects of kappa-opioid receptor antagonists in the forced swim test in rats. J. Pharmacol. Exp. Ther. 305:323-330. 2003 DOI ScienceOn |
15 | Deyama, T, Nishibe, S, and Nakazawa, Y. Constituents and pharmacological effects of Eucommia and Siberian ginseng. Acta Pharmacol. Sin. 22:1057-1070. 2001 |
16 | Coombes, JS and McNaughton, LR. Effects of branched-chain amino acid supplementation on serum creatine kinase and lactate dehydrogenase after prolonged exercise. J. Sports. Med. Phys. Fitness 40:240-246. 2000 |
17 | Moriura, T, Matsuda, H, and Kubo, M. Pharmacological study on Agkistrodon blomhoffii blomhoffii BOIE. V. anti-fatigue effect of the 50% ethanol extract in acute weight-loaded forced swimming-treated rats. Biol. Pharm. Bull. 19:62-66. 1996 DOI ScienceOn |
18 | Novelli, GP, Falsini, S and Bracciotti, G. Exogenous glutathione increases endurance to muscle effort in mice. Pharmacol. Res. 23:149-155. 1991 DOI ScienceOn |
19 | Dorchy, H. Sports and type I diabetes: personal experience. Rev. Med. Brux 23:A211-217. 2002 |
20 | Long, D, Blake, M, McNaughton, L and Angle, B. Hematological and biochemical changes during a short triathlon competition in novice triathletes, Eur. J. Appl. Physiol. Occup. Physiol. 61:93-99. 1990 DOI |
21 | Dubovik, BV and Bogomazov, So. Multifactorial method for assessing the physical work capacity of mice. Farmakol. Toksikol. 50:116-121. 1987 |
22 | Tanaka, K, Koga, T, Konishi, F, Nakamura, M, Mitsuyama, M, Himeno, K, and Nomoto, K. Augmentation of host defense by a unicellular green alga, Chlorella vulgaris, to Escherichia coli infection. Infect. Immun. 53:267-271. 1986 |
23 | Sarac, AJ and Gur, A. Complementary and alternative medical therapies in fibromyalgia. Curr. Pharm. Des. 12 :47-57. 2006 DOI ScienceOn |
24 | Shibata, S, Oda, K, Onodera-Masuoka, N, Matsubara, S, Kikuchi-Hayakawa, H, Ishikawa, F, Iwabuchi, A and Sansawa, H. Hypocholesterolemic effect of indigestible fraction of Chlorella regularis in cholesterolfed rats. J. Nutr. Sci. Vitaminol. (Tokyo) 47:373-377. 2001 DOI ScienceOn |
25 | Naitoh, H, Yamaoka, K and Nomura, S. Behavioral assessment of antidepressants (1)-- The forced swimming test: a review of its theory and practical application]. Yakubutsu. Seishin. Kodo. 12:105-111.1992 |
26 | Cheng, FC, Lin, A, Feng, JJ, Mizoguchi, T, Takekoshi, H, Kubota, H, Kato, Y and Naoki, Y. Effects of chlorella on activities of protein tyrosine phosphatases, matrix metalloproteinases, caspases, cytokine release, B and T cell proliferations, and phorbol ester receptor binding. J. Med. Food 7:146-152. 2004 DOI ScienceOn |
27 | Nakagawasai, O, Tadano, T, Hozumi, S, Taniguchi, R, Tan-No, K, Esashi, A, Niijima, F, and Kisara, K. Characteristics of depressive behavior induced by feeding thiamine-deficient diet in mice. Life Sci. 69:1181-1191. 2001 DOI ScienceOn |
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