• Analytical Science and Technology
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• v.22 no.6
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• pp.498-503
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• 2009

Lung cancer is the main cancer on the world today, due to the high case fatality. Lung cancer can devide into two major types, such as small-cell lung cancer (SCLC) and non-small-cell lung cancer (NSCLC). Mutations in the epidermal growth factor receptor (EGFR) have been described in patients with advanced NSCLC. Mutations in the EGFR are associated with clinical and radiographic responses to EGFR tyrosine kinase inhibitors gefitinib and erlotinib. Thus, the detection of EGFR mutation can offer an effective information in clinical decision-making. In this study, We developed very simple, cheep and rapid mutation detection system by chip-based isothermal amplification method. The method described here has shown the advantages of rapid amplification, high sensitivity, and specificity. Also, it will be useful for rapid and reliable clinical diagnosis of EGFR mutation.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.18 no.2_spc
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• pp.275-289
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• 2020

In 2017, multimodal transportation tests for evaluating road, sea, and rail transport were performed by research institutes in the US, Spain, and the Republic of Korea. In this study, acceleration and strain data determined through road and sea tests were analyzed. It was investigated whether the load generated for each transport mode was amplified or attenuated according to the load transfer path. From the results, it was confirmed that the load transfer characteristics differed according to the transportation mode and loading path. The effects of strain determined through each test on the structural integrity of the spent nuclear fuel were also investigated. It was found that the magnitude of the measured strain had a negligible effect on the structural integrity of the spent nuclear fuel, considering its fatigue strength. The results for the acceleration and strain data analyses obtained in this study will be useful for scheduled domestic transportation tests under normal transport conditions.

• Proceedings of the KIEE Conference
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• 2008.10b
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• pp.478-479
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• 2008

본 연구에서는 비접촉 방식으로 심박과 호흡을 측정하기 위해 2.4GHz 대역에서 동작하는 도플러 레이더 센서와 베이스밴드 모듈로 구성된 도플러 레이더 시스템을 설계하고 그 성능을 평가하였다. 설계된 도플러 레이더 시스템은 심폐활동에 의한 흉부 표면의 움직임에 의해 반사되는 레이더의 위상변화를 이용하여 심폐 활동을 측정한다. 도플러 레이더 센서의 출력은 베이스 밴드 모듈의 전처리 필터부, 증폭부, 오프셋 조정부를 통과하여 호흡과 심박 신호로 분리된다. 분리된 생체신호는 기존의 생체신호와 상관성을 확인하기 위해 기준신호로 호흡과 심전도를 동시에 측정하여 그 결과를 비교 및 분석하였다. 설계된 도플러 레이더 시스템에서 분리된 호흡 및 심박 신호는 측정 대상의 움직임이 없는 상태에서는 높은 검출률을 보였으며, 도플러 레이더에서 심박과 호흡 신호를 검출한 결과 거리, 호흡과 심박의 변이량, 호흡과 심박대역에 따라 검출률이 영향을 받는다는 것을 알 수 있었다.

• Journal of Korean Tunnelling and Underground Space Association
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• v.12 no.4
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• pp.295-306
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• 2010

Contrary to an intact rock, the jointed rock mass shows strain-dependent deformation characteristics (elastic modulus and damping ratio). The maximum elastic modulus of a rock mass can be obtained from an elastic wave-based exploration in a small strain level and applied to seismic analyses. However, the assessment and application of the non-linear characteristics of rock masses in a small to medium strain level ($10^{-4}{\sim}0.5%$) have not been carried out yet. A non-linear dynamic analysis module is newly developed for FLAC3D to simulate strain-dependent shear modulus degradation and damping ratio amplification characteristics. The developed module is verified by analyzing the change of the Ricker wave propagation. Strain-dependent non-linear characteristics are obtained from disks of cored samples using a rock mass dynamic testing apparatus which can evaluate wave propagation characteristics in a jointed rock column. Using the experimental results and the developed non-linear dynamic module, seismic analyses are performed for the intersection of a shaft and an inclined tunnel. The numerical results show that vertical and horizontal displacements of non-linear analyses are larger than those of linear analyses. Also, non-linear analyses induce bigger bending compressive stresses acting on the lining. The bending compressive stress concentrates at the intersection part. The fundamental understanding of a strain-dependent jointed rock mass behavior is achieved in this study and the analytical procedure suggested can be effectively applied to field designs and analyses.

• Journal of The Korean Society of Agricultural Engineers
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• v.55 no.5
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• pp.59-69
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• 2013

본 연구에서는 동적 점탄-점소성 구성식에 기초한 다층지반의 1차원 액상화 해석을 수행하였다. 일본 고베 포트아일랜드에서 발생한 1995 Hyogoken Nanbu 지진에 대하여 지반 모델링을 하였으며, 사질토 지반에는 탄소성 모델을, 점성토 지반에는 점탄-점소성 모델 및 탄-점소성 모델을 각각 적용하였다. 본 연구 결과, 모델 지반의 경우 지표 10 m 아래를 전후하여 액상화가 발생하였으며 액상화가 발생한 지반을 통과하는 지진파는 감쇠특성을 나타내고 이 때 전단변형률을 크게 증가시켰다. 또한, 대변형률 영역에서의 점성토의 동적거동 해석에서는 점소성 거동특성이 지배적이므로 점소성 모델의 적용이 중요함을 알 수 있었다. 한편 동적 점탄-점소성 구성모델은 대변형률 영역에서 점성토의 소성변형을 유발하는 대형 지진 발생시 점성토의 증폭 및 감쇠특성 분석에 적용 가능한 모델임을 확인하였다.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2006.05a
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• pp.293-294
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• 2006

The conventional strain measuring device is costly and complicated - it is not simple to understand its structure. Hence, strain gage and the A/D converter are assembled to come up with a load and a strain measuring device. The device was tested for measuring the strain in a loaded specimen and the experimental results were compared to those obtained by a commercial strain indicator.

• Proceedings of the Korean Society of Disaster Information Conference
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• 2023.11a
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• pp.335-336
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• 2023

최근 환경에 대한 관심이 지속적으로 증가함에 따라 실내 공기질에 대한 관심 역시 증폭되었다. 이에 따라 실내 공기질을 결정 짓고 흡연에 이어 폐암 사망률이 높은 라돈에 대한 관심 역시 증가하였다. 따라서 본 연구에서는 실내 라돈가스의 농도를 낮추기 위한 방법을 찾기 위해 RADON EYE RD200을 이용하여 교육연구시설에서의 세 강의동을 대상으로 라돈 방출량을 측정하고, 환기를 통해 라돈의 감소량을 측정한다. 세 강의동 모두 현재 기준치인 148 Bq/m³을 초과하는 수치를 기록하였고, 강의실을 10분간 환기한 결과 1회 환기 시 평균 77 Bq/m³만큼 감소하였고, 2회 환기 시 평균 56 Bq/m³만큼 감소하였다. 본 연구를 통해 라돈의 실태 및 위험성을 인지하고 라돈에 관련된 시설물 지침 및 환기를 강조하는 방안에 대한 마련이 필요하다고 판단된다.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.49 no.5
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• pp.66-71
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• 2012

The capacity criteria have been proposed in order to select a cooperative relay node in WSNs, under the environment where direct path has a poor link gain. This process may ensure the efficiency improvement of signal transfer between source and destination and reduction of energy consumption as well. Two criteria are incorporated to select a cooperative relay node. Firstly, calculate the energy gain ratio between the relay path and the direct path. These are defined as the ratio between the energy factors of 1/g and 1/B. Each stands for an inverse of direct path gain and relay path gain. Secondly, investigate the effects of relay node's usage in WSNs through the simulation in terms of energy consumption. In conclusion, using a selected cooperative relay node based on the selected criteria is effective in terms of both energy efficiency and capacity of WSNs especially when direct path gain is relatively low.

• Journal of the Korean Chemical Society
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• v.50 no.3
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• pp.208-215
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• 2006

A simply prepared graphite, pencil-type working electrode was utilized to monitor fenitrothion concentrations, using the cyclic voltammetry (CV) and square-wave (SW) stripping voltammetry methods. The optimum conditions for analysis were sought. A very low detection limit was obtained compared to that obtained when other common voltammetry methods are used. The optimal parameters of the pencil-type electrode were found to be as follows: a pH of 3.7, a frequency of 500 Hz, an SW amplitude of 0.1 V, an increment potential of 0.005 V, an initial potential of -0.9V, and a deposition time of 500 sec. The analytical detection limit was determined to be 6.0 ngL-1 (2.16410-11 molL-1) fenitrothion at SW anodic and CV, and the relative standard deviation at the fenitrothion concentration of SW anodic 10 ugL-1 was 0.30% (n = 15) under the optimum conditions. Analysis was directly conducted through in-vivo real-time assay.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.25 no.1B
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• pp.8-14
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• 2000

This paper analyzes and accesses the gain of optically pumped surface-normal MQW optical amplifiers. The proposed amplifiers have the advantage of polarization independence, high coupling efficiency to and from optical fibers, and flexibility of operating wavelength. We analyzed the gain characteristics of 100 - 200-period MQWs and verified the dependence of a strained lattice and selective doping. Theoretical analysis of such MQWs showsa single-pass gain of 3 dB with broad operation bandwidth. A single-pass gain of 2.6 dB is obtained experimentally in an InGaAs/InGaAlAs MQW amplifier, which is compared with calculations. The use of Fabry-Perot interferometer (FPI) structure in an optical amplifier is a useful way to increase the gain, but causes a problem of narrow operation bandwidth when the single-pass gain is low. Therefore, a single-pass gain above 2to 3 dB is a prerequisite to achieve both a high gain and moderate operation bandwidth in FPI-structured opticalamplifiers. We have designed an FPI-structured surface-normal optical amplifier both with a high gain of broad operation bandwidth of 4.6mm, when a single-pass gain is 3 dB.