• Journal of the korean Society of Automotive Engineers
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• v.26 no.4
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• pp.17-22
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• 2004

위성항법시스템(GPS)을 이용하여 목적지까지의 최적경로를 보여주는 경로안내시스템은 이미 상용화 단계에 도달하였으며, 최근에는 차량에 내재된 모뎀을 통해 통신기지국과 접속하여 사고 시 즉시 응급기관에 연락이 가능하도록 하는 장치의 설치 등이 정보통신기술의 발달로 가능하게 됨으로써 자동차는 이제 단순한 탈것에서 위치이동 시 일어날 수 있는 제반 상황에도 대처할 수 있는 움직이는 비즈니스 공간으로 탈바꿈하고 있다. (중략)

• Information and Communications Magazine
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• v.11 no.3
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• pp.50-58
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• 1994

정보고속도로 구축과 더불어 가장 먼저 대두되는 서비스로 비디오 대역 서비스, Video On Demand가 주목되고 있다. 우리나라 말로 하면 $\ulcorner$요구즉시형 비디오$\lrcorner$라 불리운다. 가입자가 비디오 가계에 직접 가지 않고 가입자 장비를 통해 선택하면 바로 극장에서와 같은 화질의 비디오가 2,3분 내에 방영되는 것이다. 본고에서는 이 서비스에 대한 개요, 및 구성에 대해 고찰 해 보겠다.

• Tuberculosis and Respiratory Diseases
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• v.48 no.2
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• pp.191-202
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• 2000

Background: Bronchial asthma is characterized by airway hyperresponsiveness(BHR) and inflammation. The cyclooxygenase(COX) is believed to be one of the important enzymes in these inflammatory reactions. Recently, the COX was divided into two isoforms, COX1 and COX2. COX2 is induced by lipopolysaccharide and some cytokines at the inflammation site. Prostaglandin E2(PGE2), produced from COX2, may affect airway inflammation. The purpose of this study is to evaluate the effect of COX2 inhibitor on COX2 expression, plasma PGE2, airway resistance and histologic finding in an animal asthma model. Methods : Sprague-Dawley rats were divided into 3 groups. The normal control group did not receive any treatment, but the asthma control group was sensitized by ovalbumin but not treated with the COX2 inhibitor(nimesulide, Mesulid$^{(R)}$). The treatment group was sensitized and treated with nimesulide. Specific airway resistance(sRaw) before and after nimesulide ingestion was investigated. The PGE2 level in the plasma was examined and COX2 immunogold-silver stain on lung tissue was performed. Results: sRaw and eosionophilic infiltration on airway, which increased in the asthma control group, was compared to normal control(p=0.014). However, there was no difference in eosinophilic infiltration between asthma control and treatment groups(p=0.408) and no difference in COX2 expression on bronchiolar epithelium among the three groups. Plasma PGE2 levels were not statically different among the three groups. Conclusion: The role of COX2 in the allergen-induced BHR was not significant The effect of nimesulide was not observed on BHR, COX2 expression, and plasma PGE2 level. Therefore, COX2 may not be a major substance of allergic asthma.

• Proceedings of the KIPE Conference
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• 1999.07a
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• pp.214-217
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• 1999

IGBT 소자는 고전류 밀도의 특성을 지니면서 구동전력이 작기 때문에 500V 이상의 고전압 응용에서 널리 이용되고 있다. 본 논문에서는 기존의 IGBT 소자의 구동회로가 갖는 기본기능 이외에 소자에 대한 보호기능과 소자의 동작 상태를 감지하기 위한 모니터링 기능을 갖는 지능형 구동회로에 대해 제안한다. 제안된 회로는 소자에 비정상적인 큰 전류가 흐를 경우 논리회로에 의해 게이트 구동전압을 일정시간 즉시 차단하여 소자를 과전류와 과열로부터 보호하고, 소자의 동작 상태가 정상인지 차단 상태인지 감지할 수 있다. 언급한 기능을 가진 구동회로가 제시되며, 제안된 회로의 동작은 Pspice를 이용한 시뮬레이션 및 실험을 통해 확인된다.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.5
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• pp.1270-1275
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• 2003

The purpose of this research was to investigate the effects of Kamihyungbangjihwang-tang (KHT) on immediate-type allergic reaction. KHT was composed of hyungbangjihwangtang (HJT) and Rubus coreanus Miquel (RC) and Aspalathus linear is (AL). KHT and HJT (500 mg/kg) inhibited the systemic anaphylaxis induced by compound 48/80 and inhibited the passive cutaneous anaphylaxis (PCA) induced by anti-dinitrophenyl (DNP)-IgE and DNP-human serum albumin (HSA) in vivo. In addition, KHT, HJT, RC and AL inhibited the release of histamine and increased the release of cAMP from rat peritoneal mast cells. The anti-allergic action of KHT was more potent than those of HJT. These results indicate that KHT may be useful for the prevention and treatment of type I allergy related disease via inhibition of histamine release from mast cells.

• YAKHAK HOEJI
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• v.42 no.3
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• pp.319-323
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• 1998

Effects of the aqueous extract of Cryptotympana atrata Fabricius (CAF) on the allergic reactions were investigated. In the present study, we examined the effect of CAF on compound 48/80-induced anaphylaxis in vivo and histamine release from rat peritoneal mast cells in vitro. CAF dose-dependently inhibited systemic anaphylaxis induced by compound 48/80 in mice. CAF significantly inhibited serum histamine levels induced by compound 48/80. CAF also inhibited histamine release from the rat peritoneal mast cells activated by compound 48/80. These results suggest that CAF may be useful for the prevention and treatment of allergy related disease.

• YAKHAK HOEJI
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• v.46 no.6
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• pp.405-410
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• 2002

The effect of aqueous extract of Lycopus lucidus Turcz. (Labiatae)(LLAE) on mast cell-mediated immediate-type allergic reactions was investigated. LLAE (0.01 to 1 mg/g) dose-dependently inhibited systemic anaphylaxis induced by compound 48/80. LLAE (0.001 to 1 mg/g) also dose-dependently inhibited local anaphylaxis activated by anti-dinitrophenyl (DNP) IgE. When LLAE was pretreated at the same concentration with systemic anaphylaxis, serum histamine levels were reduced in a dose-dependent manner. LLAE (0.001 to 1 mg/mι) dose-dependently inhibited histamine release from rat peritoneal mast cells (RPMC) activated by compound 48/80. The level of cAMP in human mast cell line (HMC-1) cells, when LLAE (1 mg/mι) was added, significantly was increased, compared with that of normal control. These results provide evidences that LLAE may be beneficial in the treatment of allergic diseases.

• Korean Journal of Pharmacognosy
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• v.34 no.2 s.133
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• pp.132-137
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• 2003

The effect of aqueous extract of Isodon japonicus Hara (Labiatae) (IJAE) on mast cell-mediated immediate-type allergic reactions was investigated. IJAE inhibited compound 48/80-induced systemic anaphylaxis and immunoglobulin E (IgE)-mediated local anaphylaxis. When IJAE was pretreated at the same concentration with systemic anaphylaxis, serum histamine levels were reduced in a dose-dependent manner. IJAE dose-dependently inhibited histamine release from rat peritoneal mast cells (RPMC) activated by compound 48/80. The level of cAMP in human mast cell line (HMC-1) cells, when IJAE was added, significantly was increased, compared with that of normal control. These results indicate that IJAE will beneficial in the treatment of immediate-type allergic reaction.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 1999.05a
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• pp.113-119
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• 1999

본 논문에서 구현한 평가 시스템은 클라이언트/서버 환경 하에서 교사로 하여금 서버에 저장되어 있는 문제은행을 자신의 PC에서 손쉽게 관리하고, 인터넷을 통해 학생들을 테스트할 평가 문제를 자유롭게 출제할 수 있도록 투명성을 제공하고 있다. 또한 테스트 결과를 다양하게 통계 처리하여 보여줌으로써 교사가 학생 및 학급별 학습 능력 수준을 손쉽게 파악할 수 있도록 처리하였다. 학생들은 인터넷 접속을 통해 문제를 풀고 즉시 보여지는 채점 결과를 통해서 자신의 오답과 정답을 즉시 비교해 볼 수 있으며, 더불어 문제 해설 부분을 통하여 보충학습의 효과를 얻을 수 있도록 하였다. 이에 본 논문은 교사가 학생 수준에 적합하게 학생들을 개별 지도할 수 있는 자료를 제공함으로써 기존의 교사 주도적이고 획일화된 주입식 교육 방식의 문제점을 해결하며, 이를 통해 학생들에게 학습 의욕을 향상시킬 수 있는 기회를 제공하고자 하였다.

• YAKHAK HOEJI
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• v.41 no.2
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• pp.268-272
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• 1997

We studied the action of methyleugenol on immediate hypersensitivity. Methyleugenol completely inhibited systemic anaphylaxis induced by compound 48/80 in mice. Methyleugenol al so inhibited local anaphylaxis induced by anti-dinitrophenyl (DNP) IgE. Moreover, methyleugenol dose-dependently inhibited histamine release in peritoneal mast cells activated by compound 48/80 or anti-DNP IgE. These results suggest that the inhibitory effect of methyleugenol on anaphylaxis induced by compound 48/80 or anti-DNP IgE is due to, in part at least, the membrane stabilization of mast cells.