• Journal of the Korean Society of Food Science and Nutrition
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• v.25 no.1
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• pp.21-26
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• 1996

본 연구는 streptozotocin 유발 당뇨쥐에서의 MFO계활성 변화 및 이에 지질과산화를 관찰하고자 체중이 140kg 내외의 Sprague-Dawley 종 흰쥐 숫컷을 대조군과 당뇨 유발 시험군으로 나누어 4주간 사육하였다. 당뇨군은 STZ로 당뇨를 유발시켰으며 당뇨 유발 6일후 쥐를 희생기켜 간조직 및 폐조직 microsome 중의 cytochrome $P_{450}$ 및 cytochrome $b_[5}$ 함량과 NADPH-cytochrome $P_{450}$ reductase 활성도를 측정하고 아울러 microsome내의 지질과산화물을 측정하여 다음과 같은 결과를 얻었다. 실험군간에 식이 섭취량은 차이가 없었으나, 체중 증가량과 식이 효율은 당뇨군이 STZ군에 비해 현저하게 감소하였다. 간장 및 폐조직의 무게는 대조군과 당뇨군간에 유의적인 차이는 없었다. 간조직 및 GP조직 중의 cytochrome $P_{450}$ 함량은 대조군에 비해 당뇨군이 150%, 175%씩 증가하였다. 간조직 및 폐조직 중의 cytochrome $b_{5}$은 대조군에 비해 당뇨군이 53%,116%씩 각각 증가하였다. 간조직에서의 NADPH-cytochrome $P_{450}$ reductase 활성은 당뇨군이 대조군에 비해 46% 증가하였으며, 폐조직에서는 75%증가하였다. 지질과산화물가는 당뇨군이 대조군에 비해 간족에서는 약 95% 높았으며 폐조직에서는 73%높았다. 이상의 결과에서 STZ 유발 당뇨쥐에서는 MFO system의 활성도가 대조군에 비해 현저하게 증가되고 지질과산화반응이 같으 srudgid이 촉진되었으며 폐조직에서도 간조직에서와 비슷한 경향이었다. 이러한 것은 당뇨군에서는 MFO system의 활성증가로 free radical 생성이 증가되고 그 결과 지질과산화가 촉진되었다고 볼 수 있다.

• Korean Journal of Food Science and Technology
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• v.27 no.2
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• pp.170-175
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• 1995

Physical and physiological properties of isomaltooligosaccaride (IMO), fructooligosaccharide (FO) and sucrose were investigated. The viscosity and moisture retention power of IMO were similar to those of FO. IMO had an excellent heat and pH stability compared with FO and sucrose. To investigate the effect of oligosaccharides on the growth of mice, each sample was administered orally to mice for 2 weeks. Weight change, moisture content of feces, weight of appendix and the ratio of Bifidobacterium to total microorganisms in the feces were examined. There were no significant differences in the weight increases and the efficiency of feeds. Moisture content of feces was highest in the IMO feeding group, and IMO promoted selectively the growth of Bifidobacterium. On the other hand, FO group showed bigger cecum than other groups.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.20 no.1
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• pp.6-10
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• 1984

The author carried out an experiment to find out the response of rock trout, Hexagrammos otakii (Jordan et starks) to the color lights. The experimental tank (360L$\times$50W$\times$55H cm) was set up in a dark room. Six longitudinal sections with 60cm intervals are marked in the tank to observe the loction of the fish. Water depth in the tank was kept 50cm level. Light bulbs of 20W at the both ends of the tank projected the light horizontally into the tank. Two different colored filters were selected from four colors of red, blue, yellow, and white, and they were placed in front of the light bulbs to make different colors of light. Light intensity were controlled by use of auxiliary filters intercepted between the bulb and the filter. The fishes were acclimatized in the dark for 50 minutes before they were 3employed in the experiment. Upon turning on the light, the number of fish in each section was counted 40 times in 30 second intervals, and the mean of the number of fish in each section was given as the gathering rate of the fish. The colors favourited by the fish was found in the order of white, yellow, red and blue in day time, and red, yellow, blue and white at night time. The gathering rate of fish on illumination period was small and comparatively fluctuated with stability. The difference of the gathering rates on two different colors of light was great.

• Journal of Life Science
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• v.21 no.3
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• pp.406-411
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• 2011

To investigate the effects of short-term treatment with tri-n-butyltin chloride (TBTCl) and bisphenol A (BPA) on the reproduction of striped field mice, the mice were intramuscularly injected with TBTCl or BPA immediately before the reproductive season and examined in the reproductive season after keeping them for 4 months. As a result, there were no differences between the control and the compound-treated groups regarding body weight in both sexes, the residual levels of the compounds in the adult males, and the gonadosomatic index (GSI) and the histological structures with LM and EM of the testes and epididymides in both the adult and young males. The infant mortality and abortion rate, however, were high in the TBTCl-treated groups and BPA-treated groups respectively, compared to the control group. Conclusively, it was suggested that short-term treatment with TBTCl or BPA in mice in the non-reproductive season might have inhibited the development of the uterine embryos or fetuses, although it did not induce accumulations of these compounds or affect the reproductive organs of adult and young (F1) males.

• The Korean Journal of Zoology
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• v.33 no.3
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• pp.297-302
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• 1990

The effects of ginseng saponin on the activity of serum alanine aminoiransferase (ALT) in trained rats were examined. The trained group was given a chronic swimming bout (approx. 90 min/day) for 50 days, and ginseng group was given an oral administration of ginseng saponin (150mg/kg/day) for 2 weeks. Ginseng treated-trained group was given an oral administration of ginseng saponin for 2 weeks prior to the termination of a swimming bout. In this experiment, male rats of Sprague-Dawley strain (250 $\pm$ 20 g) were used. The activities of serum ALT in trained and in ginseng groups increased 72.89% (P < 0.01) and 57.14% (P < 0.01) than in control groups, respectively. Also, the activities of serum ALT increased 69.66% (P <0.01) in saline treated-trained group, and 79.31% (P < 0.01) in ginseng treated-trained group than in control groups which were given saline solution and kept sedentary. The effect of ginseng saponin, as revealed by comparing the ginseng treated-trained group with the saline treated-trained group, was not significant. The present study suggests that training and ginseng saponin significantly increased the activity of serum ALT in rats, but that, in ginseng treated-trained group, ginseng saponin did not raise any further the increased activity of serum ALT by training.

• Journal of the Korean Society of Radiology
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• v.13 no.5
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• pp.811-817
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• 2019

Radiation-therapy causes the adverse radiation effect. It is called osteoradionecrosis. A protein-therapy is carried out in order to cure osteoradionecrosis. The typical method of the protein-therapy is using BMP-2. Considering to bone damage, it is more important that maintains enough to circumstance regeneration for osteoblast differentiation on damage site of bone. Thus, this study is on a tissue regeneration to cure radiation critical damage. I observed that the formation of new regeneration bone by injection of collagen sheet BMP-2 on irradiated mouse. Consequently, I examined new bone formation with collagen sheet BMP-2 on irradiated mouse after 8weeks. Therefore I suggested that using collagen sheet BMP-2 which can be good for new bone regeneration effect on radiation side effect area.

• Korean journal of applied entomology
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• v.39 no.4
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• pp.281-286
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• 2000

Non-chemical or low-chemical control measures against key insect pests and rats in the ginseng field were studied from 1993 through 1999. Broadcasting chemicals beside the ginseng field in the oviposition period showed the same control effect on the adults of the Korean black chafer, Holotrichia diomphalia, as broadcasting at the ginseng ridge. Ginseng damage by adults of African mole cricket, Gryl1ota1pa africana, were reduced considerably by broadcasting chemicals beside the ginseng field. The larvae of wheat wireworm, Ectinus sericeus, were attracted effectively to potatoes in the ginseng field. Spreads of the mealybug, Pseudococcus comstocki, were very slow in the ginseng field, indicating that it is possible to eradicate the early colonies of Pseudococcus comstocki effectively. The rat repeller, Dekur $500S^{showed}$ a significant control effect of rats in the ginseng field.

• Journal of the Korean Applied Science and Technology
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• v.40 no.2
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• pp.244-257
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• 2023

This study investigated the effects of exercise on genistein-induced adipose tissue reduction and anti-inflammation of adipose tissue in ovariectomized mice fed a high-fat diet. Compared to mice fed a high-fat diet (C), both genistein (G) or exercise only (Ex) not only decreased adipose tissue weight and adipocyte size, but also glucose and free fatty acid levels in serum, which were more effectively reduced when genistein and exercise were treated simultaneously (G/Ex). The expression of lipogenesis and inflammatory cytokine genes of both G and Ex in adipose tissue was decreased compared to C. In particular, the decrease of these genes expression in G/Ex was more effective than each treatment alone. Thus, this study revealed that simultaneous treatment of genistein and exercise resulted in more effective improvement of obesity and adipose tissue inflammation than genistein single treatment in ovariectomized mice fed a high-fat diet, and it is a result of positive regulation of lipogenesis genes. This study suggests that the exercise has a beneficial effect on anti-obesity and adipose tissue anti-inflammation of genistein.

• Journal of Nutrition and Health
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• v.14 no.3
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• pp.129-135
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• 1981

Low phenylalanine diet(0.05%) was given to the Sprague Dawley pregnant rats at the 14 days of gestation and continued until the pups were lactated for 11 days. Body weight, plasma phenylalanine and tyrosine, brain weight, and brain phenylalanine and tyrosine were determined on pups randomly sacrificed at several intervals. Body weight of pups on normal diet (0. 36% phenylalanine) gained rapidly while the pups on the phenylalanine deficient diet decreased and did not survive during the period of 11 days. Brain weight of the pups on the phenylalanine deficient diet was significantly lower(P < 0.05) than the normal pups. Phenylalanine deficient diet did not affect the level of plasma phenylalanine of pups, but it seems that there was a positive correlation between the level of phenylalanine in the diet and the plasma tyrosine level. The plasma tyrosine level of pups on the deficient diet was decreased significantly during the Period while the pups on the normal diet increased steadily. Phenylalanine and tyrosine level in the brain was lower in Pups on the deficient diet than the pups on normal diet but the plasma phenylalanine level was not significantly different in both diets. However, plasma tyrosine level was significantly lower in the pups on the deficient diet than the normal diet at the end of the period.

• Korean Journal of Environmental Biology
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• v.38 no.1
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• pp.1-15
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• 2020

This study was conducted to determine whether invasive muskrats settle in the natural ecosystem of Korea. The study also aimed to provide information on the selection of target areas, basic behavioral characteristics, and habitat use-related data, all of which are essential for effective management strategy establishment and site management. To this end, a trend in international muskrat management was identified to examine the management direction according to the settlement stage. We also secured the location of 72 domestic farmers and classified five regions in Gyeonggi-do, Chungcheongnam-do, Gyeongsangbuk-do, and Sejong Special Self-governing City into regions with high potential for natural leakage to raise the need for a quick survey. We determined that muskrats successfully settled in the natural ecosystem of Korea, based on the fact that we consistently identified a muskrat habitat at the same point for three years, from 2016 to 2018, the age of the captured population was estimated to be 1.2 years, and there had been no additional make-up factors near the habitat since 2012. The muskrats that settled in Korea showed a small home range of 0.0027 ㎢ (MCP 95%) and were estimated to show regular mobility before Spring and Autumn. Also, the areas where the muskrat habitat was observed had a high level of habitat environment disturbance and their ecological and food intake characteristics reflected that disturbance. Muskrat traces were high in hydrophyte vegetation, which can be used as a hideout in open waters and where the growth of both floating leaved plants and floating plants are prevalent. Since international invasive muskrats have already settled in the domestic ecosystem and there is concern about their proliferation in the future, the government must consider a preemptive response and scientific management.