• 대한한방부인과학회지
• /
• 제22권1호
• /
• pp.263-278
• /
• 2009

Purpose: The purpose of this study is to research trends in the study of breast cancer in Traditional Chinese Medicine (TCM) and to establish the further direction for its study. Methods: We reviewed TCM papers published in the last 29 years (1979-2008). Results: 1. We researched 49 papers and the patterns of study were as follows: in vitro studies were 27 papers (55.1%), in vivo studies were 9 papers (18.4%) and clinical studies were 19 papers (38.8%). 2. In vitro studies on breast cancer research in TCM were focused on cytotoxicity (17 papers) and apoptosis (8 papers). Most of in vivo studies (6 papers) were done for the purpose of inducing growth suppression of tumor cell after administration of the test drug. Each drug acted on this effect through various types of mechanism. 3. Unlike in vitro and in vivo studies, clinical studies on growth suppression of tumor cell were rare (4 papers). Most of the studies were focused on reduction of side effect of chemotherapy or synergistic effect with chemotherapy (7 papers), immune regulation (7 papers), and improvement of quality of life (6 papers). 4. Among the treatment method we reviewed, 'Runing Ⅱ(Ⅱ號方)' was the only medication that further studied as clinical trial after experimental study. 5. Since almost all studies have defects like poorly designed model or insufficient data description, it was difficult to make any definite conclusion about these studies. Conclusion: More subsequent clinical studies based on experimental study will be needed afterwards. Strict and high-level study design with detailed description will be needed in further study.

• 정보관리학회지
• /
• 제22권2호
• /
• pp.125-145
• /
• 2005

이 연구에서는 문헌 및 질의의 내용을 대표하는 주제어의 중의성 해소를 위해 대표적인 지도학습 모형인 나이브 베이즈 분류기와 비지도학습 모형인 EM 알고리즘을 각각 적용하여 검색 실험을 수행한 다음 주제어의 중의성 해소를 통해 검색 성능의 향상을 가져올 수 있는지를 평가하였다. 실험문헌 집단은 약 12만 건에 달하는 한국어 신문기사로 구성하였으며, 중의성 해소 대상 단어로는 한국어 동형이의어 9개를 선정하였다. 검색 실험에는 각 중의성 단어를 포함하는 18개의 질의를 사용하였다. 중의성 해소 실험 결과 나이브 베이즈 분류기는 최적의 조건에서 평균 $92\%$의 정확률을 보였으며, EM 알고리즘은 최적의 조건에서 평균 $67\%$ 수준의 클러스터링 성능을 보였다. 중의성 해소 알고리즘을 통합한 의미기반 검색에서는 나이브 베이즈 분류기 통합 검색이 약 $39.6\%$의 정확률을 보였고, EM 알고리즘 통합 검색이 약 $36\%$의 정확률을 보였다. 중의성 해소 모형을 적용하지 않은 베이스라인 검색의 정확률 $37\%$와 비교하면 나이브 베이즈 통합 검색은 약 $7.4\%$의 성능 향상률을 보인 반면 EM 알고리즘 통합 검색은 약 $3\%$의 성능 저하율을 보였다.

• 대한한방소아과학회지
• /
• 제37권2호
• /
• pp.12-27
• /
• 2023

Objective This study aimed to analyze the efficacy of the tuina treatment for congenital muscular torticollis based on randomized controlled clinical studies in China. Methods The China National Knowledge Infrastructure was the main source of data. Using the keywords "tuina", "chuna", "推拿", and "斜颈", 12 randomized controlled clinical studies were identified and analyzed. Results Compared with the control group, the tuina treatment group showed statistically significant changes with respect to the therapeutic effect. Conclusions This study suggests that tuina treatment is effective for congenital muscular torticollis patients and provides evidence for further studies on oriental medicine treatments, including tuina for congenital muscular torticollis.

• 대한한방소아과학회지
• /
• 제35권4호
• /
• pp.82-95
• /
• 2021

Objectives The purpose of this study is to analyze clinical studies on the effectiveness of TCM (traditional Chinese medicine) for pompholyx treatment and provide evidence for Korean medicine use. Methods Randomized controlled trials (RCT) which used TCM as a treatment for pompholyx were searched in China National Infrastructure (CNKI) platform. The risk of bias of studies was assessed by using Cochrane risk of bias (RoB) 2.0 tool. Results The selected 10 RCTs showed that the experimental group treated with either TCM alone or with a combination of TCM and Western medicine showed more significant therapeutic effect compared to the control group which Western medicine alone. Conclusions Based on the studies from China, TCM may be an effective treatment for pompholyx. This provides evidence for Korean medicine use, and its possible effectiveness in treating pompholyx

• 동의신경정신과학회지
• /
• 제31권4호
• /
• pp.315-327
• /
• 2020

Objectives: The aim of this study was to review the research trends in the treatment of pharmacopuncture for vascular dementia in Traditional Chinese medicine. Methods: We searched for articles in the China National Knowledge Infrastructure (CNKI) database from January 2000 to August 2020. Results: Among the total 63 articles, 9 articles were selected. All studies were randomized controlled trial studies. The Diagnostic and Statistical Manual of Mental Disorders (DSM) was most frequently used as diagnostic criteria. Effective rate and Activity of Daily Living (ADL) were most commonly used as outcome measurements. Angelica gigantis Radix (當歸), Salvia miltiorrhiza Bunge (丹蔘), and Astragali Radix (黃芪) were the most commonly used ingredients in pharmacopuncture. Joksamni (ST36) and Sinsu (BL23) were the most commonly used acupoints for pharmacopuncture treatment. Based on the Risk of Bias (RoB) of these 9 articles, the overall quality of studies was low. Conclusions: Pharmacopuncture could be considered for the treatment of vascular dementia. In the future, various systematic studies on dementia are needed.

• 대한한방소아과학회지
• /
• 제36권3호
• /
• pp.63-74
• /
• 2022

Objective This study aimed to analyze the efficacy and safety of Tuina therapy for attention-deficit hyperactivity disorder (ADHD) through a randomized controlled clinical study in China. Methods We used the China National Knowledge Infrastructure (CNKI) as a resource and conducted a search using key words: 'ADHD', '推拿'. Six randomized control studies were identified and analyzed in this study. Results 1. The Tuina treatment group showed significant changes compared to the control group. 2. The most commonly used meridians were Spleen meridian (脾經穴), Liver meridian (肝經穴), Errenshangma (二人上馬穴), Xiaotianxin (小天心), Qinghetianshu (清河天水), Kidney meridian (腎經穴). Conclusions The results of this study showed that Tuina therapy is effective for ADHD patients with ADHD. It can be used for future research on Tuina therapy for ADHD.

• 대한한방부인과학회지
• /
• 제36권4호
• /
• pp.21-39
• /
• 2023

Objectives: The purpose of this study is to review the overseas clinical study trends on Chinese Medicine treatment for Pre-eclampsia. Methods: We searched articles published from Pubmed, Embase and CNKI. The period was set from 2004 to 2023. Searched keywords were "Pre-eclampsia", "Preeclampsia", "Chinese medicine", "Herbal medicine", "子癎前期", "子癎前症", "中藥", "中醫". Results: 21 articles were finally selected. There were 16 RCTs, 3 case control studies, 2 case series. 2 articles used both acupuncture and western medicine, 19 articles used both herbal medicine and western medicine. 風池 (GB20), 太衝 (LR3), 足三里 (ST36) were the most frequently used acupoints, Paeoniae Radix alba (白芍藥) is the most frequently used in herbal medicine treatment. Conclusions: Our review found that chinese medicine combined with western medicine is more effective for alleviating symptoms of pre-eclampsia.

• 대한한방소아과학회지
• /
• 제38권2호
• /
• pp.41-52
• /
• 2024

Objectives The objective of this study was to investigate the impact of applying acupuncture as intervention of peripheral facial paralysis in children. Methods We conducted searches on China National Knowledge Infrastructure and Wanfang Data using the keywords "facial paralysis", "children", and "acupuncture". Results Six randomized controlled trials were included in the analysis. The acupoints most frequently utilized were Hapgok (LI4), Jichang (ST4), Yangbaek (GB14), Sabaek (ST2), Hyeopgeo (ST6), Yeonghyang (LI20), Yepung (TE17), and Taeyang (EX-HN5). The Stomach Meridian (ST) was the most targeted. Acupuncture treatment was found to be as effective as or more effective than Western medicine treatment in certain cases. Conclusions Acupuncture therapy shows promise for treating pediatric peripheral facial paralysis. However, further clinical randomized controlled trials are necessary to validate the efficacy and safety of acupuncture treatment.

• 대한한방소아과학회지
• /
• 제38권2호
• /
• pp.53-67
• /
• 2024

Objective This study aimed to assess the trend of randomized clinical trials conducted in China involving oral herbal medicine for treating adolescent polycystic ovary syndrome (PCOS). Methods We used the China National Knowledge Infrastructure as our primary resource and conducted a search using keywords such as "PCOS", "多囊卵巢" and "多囊卵巢综合征". We identified and analyzed seven RCTs. Results 1. The group receiving herbal medicine treatment demonstrated significant improvements in total efficiency, sex hormone levels, and ultrasound-measurable values compared to the control group. 2. Epimedii Herba (淫羊藿), Alviae Miltiorrhizae Radix (丹參), and Angelicae Gigantis et Acutilobae Radix (當歸) were among the most used herbs in Traditional Chinese medicine decoctions for treating PCOS. Conclusions The findings suggest that oral herbal medicine is an effective treatment for patients with PCOS. This study provides a foundation for future research on the use of oral herbal medicine in PCOS treatment.

• 대한한방종양학회지
• /
• 제3권1호
• /
• pp.193-206
• /
• 1997

Stomach cancer is one of the most important cause of death. So recently, the first consideration Chinese Medicine Journal(after 1990th) to study on stomach cancer treatment(Herb medicine) and side effect on chemical therapy after side effect rate studied. According to the literally study of journal, the results run as follow. Herb medicine use in combination therapeutic method on stomach cancer decreased reaction.(G-I trouble, marrow and hematisis system) We expect that herb medicine treatment effects give to good advantage on stomach cancer.