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Effect of Onion Consumption on Cardiovascular Disease in Human Intervention Studies: A Literature Review (국내.외 인체중재연구를 통해 살펴 본 양파의 심혈관계 질환 개선효과에 관한 고찰)

  • Kim, Jung-Mi;Park, Eun-Ju
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.39 no.10
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    • pp.1565-1572
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    • 2010
  • Onion (Allium cepa L.) production in Korea has increased gradually over the past 15 years, placing second in food consumption survey with 20.6 g daily intake in 2006. Onions, used as an ingredient in many dishes and accepted by almost all traditions and cultures, have been reported to have a range of health benefits which include anticarcinogenic, antiasthmatic, antibiotic, and antioxidative effects. These effects may be attributable to a powerful flavonoid pigment-containing compounds, such as quercetin and alk(en)yl cysteine sulphoxides (ACSOs). Although antiplatelet and antithrombotic activities of onion have been confirmed by many of in vitro or animal studies, only a few human intervention studies have been examined. The majority of human studies identified that onion improves some cardiovascular markers such as lipid profile and platelet coagulant. With regard to antioxidative effects, somewhat positive effects are confirmed through strengthening the resistance of oxidative DNA damage in lymphocyte and urine, while most studies failed to find inhibitory effects on LDL oxidation. The discrepancies among studies might be ascribed to producing area, processing methods of onion, dosage, subject characteristics, study duration, and measurement methods. In this review, we focused on the preventive effect of cardiovascular disease through onion consumption in human intervention studies.

Effects of Phyto-Extract Mixture on Adiposity and Serum Lipid Levels in Obese Mice Induced by High Fat Diet (고지방식이로 유도된 비만쥐에서 식물혼합 추출물의 체지방 형성 및 혈청 지질에 미치는 영향)

  • Jang, Young-Sun;Jeong, Jong-Moon
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.39 no.10
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    • pp.1439-1445
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    • 2010
  • In this study, we investigated the inhibition of phyto-extract mixture (PEM) in several digestive enzymes ($\alpha$-amylase, $\alpha$-glucosidase and lipase) for anti-obesity. The current study also examined the effects of PEM on adiposity and serum lipid levels in obese mice fed with high fat diet. ICR male mice weighing $33{\pm}1.1\;g$ were randomly divided into three groups, one normal diet group (control, ND group) and two high fat diet groups with or without PEM supplement (HFD group and PEM group). The mice were fed the PEM experimental for 6 weeks and then they were sacrificed. The results showed that the final weight, weight gain, food efficiency ratio and body fat were decreased by the addition of PEM compared to those of HFD group. White adipose tissue weights of epididymal, mesenteric and retroperitoneal areas in the PEM group were reduced to 31.2%, 8.8%, and 37.8%, respectively, compared to the HFD group. The levels of serum triglyceride, total cholesterol, LDL-cholesterol in the PEM group were significantly lower than those of HFD group. The body weight gain and food efficiency ratio of PEM group were significantly lower compared with those of HFD group. From the above results, the PEM may be effective material for anti-obesity through reducing serum triglyceride and body fats as well as decreasing body weight.

Processings of flavoring Substances from Small Kingfish (소형 갈전갱이를 이용한 풍미소재의 개발)

  • Oh, Kwang-Soo;Kim, Jin-Soo;Hur, Jong-Wha
    • Korean Journal of Food Science and Technology
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    • v.30 no.6
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    • pp.1339-1344
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    • 1998
  • To develop natural flavoring substances, optimal hydrolysis conditions for two stage enzyme hydrolysates (TSEH) using small kingfish (Maegari) were investigated. The optimal conditions for TSEH were revealed in temperature at $50^{\circ}C$ for 3 hours digestion with alcalase (Aroase AP-10, pH 8.0) at the 1st stage and 2 hours digestion at $45^{\circ}C$ with neutrase (Pandidase NP-2, pH 6.0) at the 2nd stage. From the results in quality tests of water extracts, autolytic extracts and 4 kinds of enzyme hydrolysates, TSEH processing method was superior to other methods on the aspects of yield, nitrogen contents, taste such as umami intensity and inhibition of off-flavor formation, and transparency of extracts. We may conclude that TSEH from small kingfish was more flavorable compared with the conventional seasoning materials, it could be utilized as the seasoning substances for fisheries processing.

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Korean Emotion Vocabulary: Extraction and Categorization of Feeling Words (한국어 감정표현단어의 추출과 범주화)

  • Sohn, Sun-Ju;Park, Mi-Sook;Park, Ji-Eun;Sohn, Jin-Hun
    • Science of Emotion and Sensibility
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    • v.15 no.1
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    • pp.105-120
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    • 2012
  • This study aimed to develop a Korean emotion vocabulary list that functions as an important tool in understanding human feelings. In doing so, the focus was on the careful extraction of most widely used feeling words, as well as categorization into groups of emotion(s) in relation to its meaning when used in real life. A total of 12 professionals (including Korean major graduate students) partook in the study. Using the Korean 'word frequency list' developed by Yonsei University and through various sorting processes, the study condensed the original 64,666 emotion words into a finalized 504 words. In the next step, a total of 80 social work students evaluated and classified each word for its meaning and into any of the following categories that seem most appropriate for inclusion: 'happiness', 'sadness', 'fear', 'anger', 'disgust', 'surprise', 'interest', 'boredom', 'pain', 'neutral', and 'other'. Findings showed that, of the 504 feeling words, 426 words expressed a single emotion, whereas 72 words reflected two emotions (i.e., same word indicating two distinct emotions), and 6 words showing three emotions. Of the 426 words that represent a single emotion, 'sadness' was predominant, followed by 'anger' and 'happiness'. Amongst 72 words that showed two emotions were mostly a combination of 'anger' and 'disgust', followed by 'sadness' and 'fear', and 'happiness' and 'interest'. The significance of the study is on the development of a most adaptive list of Korean feeling words that can be meticulously combined with other emotion signals such as facial expression in optimizing emotion recognition research, particularly in the Human-Computer Interface (HCI) area. The identification of feeling words that connote more than one emotion is also noteworthy.

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Phosphate Sorption on Boehmite with Eu(III): P K-edge EXAFS Fingerprinting (뵈마이트 표면의 인산염 및 Eu(III) 수착: 인(P) X-선 흡수분석(EXAFS)에 의한 연구)

  • Yoon, Soh-Joung;Bleam, William F.
    • Economic and Environmental Geology
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    • v.42 no.5
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    • pp.495-500
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    • 2009
  • Actinide sorption to the geological materials can reduce the mobility and bioavailability of radionuclides released to the environment through the development of nuclear weapons and nuclear energy. Under circumneutral pH conditions, actinide sorption can be enhanced by phosphate anions sorbed on oxide mineral surfaces as indicated by the sorption of trivalent lanthanide ions ($Ln^{3+}$), the chemical analog for trivalent actinide ions ($Ac^{3+}$). In this paper, we examined a ternary sorption system of trivalent europium ions ($Eu^{3+}$) sorbed onto boehmite (${\gamma}$-AlOOH) surfaces pre-sorbed with phosphate anions (${PO_4}^{3-}$), using extended X-ray absorption fine structure (EXAFS) spectroscopy. In the Eu-$PO_4$-boehmite ternary sorption system, $EuPO_4$ surface precipitates were formed as implicated by Eu $L_{III}$-edge EXAFS spectroscopy. Phosphorus K-edge EXAFS fingerprinting indicated a bidentate mononuclear surface complex formation of phosphate sorbed on boehmite surfaces as well as $EuPO_4$ surface precipitate formation.

Effects of Onion Kimchi Extract Supplementation on Blood Glucose and Serum Lipid Contents in Streptozotocin-induced Diabetic Rats (양파김치 추출물 투여가 Streptozotocin 유발 당뇨병 흰쥐의 혈당강하 및 혈중지질 함량에 미치는 영향)

  • Yang, Ya-Ru;Kim, Hag-Lyeol;Park, Yang-Kyun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.4
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    • pp.445-451
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    • 2008
  • The purpose of this study was carried out to examine the effects of onion kimchi extract supplementation on blood glucose level and serum lipid components in streptozotocin (STZ)-induced diabetic rats for 4 weeks. STZ was administered as a single dose (50 mg/kg BW) to induce diabetes, and the diabetic rats were divided into eight groups (normal, diabetic control, and six treatment groups). The dose of onion kimchi extract 100 (OK-100), 200 (OK-200), and 400 (OK-400) mg/kg/day or quercetin as a main compound of onion 5 (Q-5), 10 (Q-10), and 20 (Q-20) mg/kg/day were orally administered daily to STZ-induced diabetic rats for 4 weeks after STZ injection. The diabetic control rats (465.6 mg/dL) showed significantly higher blood glucose level than the normal rats (76.3 mg/dL) after 4 weeks, but was significantly reduced with onion kimchi extract and quercetin supplementation (p<0.001). Changes in body weight, kidney weight and urine volume were not significantly different in diabetic control rats, and in onion kimchi extract and quercetin treated rats. The serum total cholesterol levels of control were significantly decreased in onion kimchi extract and quercetin supplementation groups, respectively (p<0.001). The blood urea nitrogen level and urinary protein excretion in diabetic rats were not significant different among the groups. These results suggest that onion kimchi extract supplementation in STZ-induced diabetic rats may be a very important factor for the reduction of blood glucose and serum cholesterol profiles.

Effects of Mountain Ginseng-added High Fat diet on Lipid Peroxidation and Antioxidant Protein Expression of Skeletal Muscle in Rats (산양삼을 첨가한 고지방식이 흰쥐 골격근의 지질과산화 및 항산화 단백질 발현 효과)

  • Kwon, Dae-Keun;Kang, Jun-Yong;Song, Youngju;Kim, Pan-Gi;Seo, Hyobin;Ryu, Sungpil
    • Journal of Korean Society of Forest Science
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    • v.101 no.1
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    • pp.69-76
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    • 2012
  • We investigated the effect of mountain ginseng-added high fat diet supplementation on lipid peroxidation and antioxidant protein expressions in rats. Thirty-two male rats were randomly divided into 4 groups; HS (high-fat diet sedentary group, n=8), MG1 (0.5% mountain ginseng-added diet group, n=8), MG2 (1% mountain ginsengadded diet group, n=8) and MG3 (2% mountain ginseng-added diet group, n=8). They have fed the diet for 4 weeks. The blood triglyceride were significantly lower in the MG1 and MG2 groups than that of the HS group. The blood HDL-cholesterol were significantly higher in the MG3 group than that of the HS and MG2 groups. The muscle glycogen contents of the MG2 and MG3 groups were significantly higher than that of HS and MG1 groups. The MDA contents in the MG1, MG2 and MG3 groups tended to lower than the HS group. The GPx protein expression in the gastrocnemius muscle of the MG2 group was significantly increased compared to that of the HS group. The Cu,Zn-SOD protein expression in the gastrocnemius muscle of the MG1 and MG2 groups was significantly increased compared to that of the MG3 group. The Mn-SOD protein expression in the MG1, MG2 and MG3 groups tended to higher than the HS group. From these results, it was suggested that mountain ginseng-added diet may have an crucial role on decreased MDA levels and increased antioxidant function in the skeletal muscle of rat fed a high fat diet.

A Case Study of Monitored Natural Attenuation at the Petroleum Hydrocarbon Contaminated Site : II. Evaluation of Natural Attenuation by Groundwater Monitoring (유류오염부지에서 자연저감기법 적용 사례연구 II. 지하수모니터링에 의한 자연저감 평가)

  • Yun Jeong Ki;Lee Min Hyo;Lee Suk Young;Noh Hoe Jung;Kim Moon Soo;Lee Kang Kun;Yang Chang Sool
    • Journal of Soil and Groundwater Environment
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    • v.9 no.3
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    • pp.38-48
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    • 2004
  • Natural attenuation of petroleum hydrocarbon was investigated at an industrial complex about 45 Km away from Seoul. The three-years monitoring results indicated that the concentrations of DO, nitrate, and sulfate in the contaminated area were significantly lower than the background monitoring groundwater under the non-contaminated area. The results also showed a higher ferrous iron concentration, a lower redox potential, and a higher (neutral) pH in the contaminated groundwater, suggesting that biodegradation of TEX(Toluene, Ethylbenzene, Xylene) is the major on-going process in the contaminated area. Groundwater in the contaminated area is anaerobic, and sulfate reduction is the dominant terminal electron accepting process in the area. The total attenuation rate was about 0.0017∼0.0224day$^{-1}$ and the estimated first-order degradation rate constant(λ) was 0.0008∼0.0106day$^{-1}$ . However, the reduction of TEX concentration in the groundwater was resulted from not only biodegradation but also dilution and reaeration through recharge of uncotaminated surface and groundwater. The natural attenuation was, therefore, found to be an effective, on-going remedial process at the site.

Effect of $H_O_2$ on the Corrosion Behavior of 304L Stainless Steel ($H_O_2$ 가 304L 스텐리스강의 부식거동에 미치는 영향)

  • Song, Taek-Ho;Kim, In-Sup;Park, Sung-Ki
    • Nuclear Engineering and Technology
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    • v.27 no.4
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    • pp.453-462
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    • 1995
  • In connection with the safe storage of high level nuclear waste, effect of $H_2O$$_2$ on the corrosion behavior of 304L stainless steel was examined. Open circuit potentials and polarization curves were measured with and without $H_2O$$_2$. The experimental results show that $H_2O$$_2$ increased corrosion potential and decreased pitting potential. The passive range, therefore, decreased as $H_2O$$_2$ concentration increased, indicating that pitting resistance was decreased by the existence of $H_2O$$_2$ in the electrolyte. These effect of $H_2O$$_2$ on corrosion of 304L stainless steel are considered to be similar to those of ${\gamma}$-irradiation. To compare the effects of $H_2O$$_2$ with those of $O_2$, cathodic and anodic polarization curves ore made in three types of electrolyte such as aerated, deaerated, and stirred electrolyte. The experimental results show that the effects of $H_2O$$_2$ on the corrosion behavior were tory similar to those of $O_2$ such as increase of corrosion potential, decrease of pitting resistance, and increase of repassivation potential. In acid and alkaline media, the corrosion potential shifts by $H_2O$$_2$ were restricted by the large current density of proton reduction and by the le Chatelier's principle respectively.y.

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Effect of Pleurotus eryngii on the Blood Glucose and Cholesterol in Diabetic Rats (큰느타리버섯이 당뇨쥐의 혈당 및 혈중콜레스테롤에 미치는 영향)

  • Kang, Tae-Su;Kang, Mi-Sun;Sung, Jae-Mo;Kang, An-Seok;Shon, Hyeong-Rak;Lee, Shin-Young
    • The Korean Journal of Mycology
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    • v.29 no.2
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    • pp.86-90
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    • 2001
  • This study was conducted to investigate the effects of Pleurotus eryngii fruiting body on blood glucose and cholesterol levels in streptozotocin-induced diabetic rats. Male Sprague-Dawley rats were used as experimental animals and experimental groups were divided into three groups, consisting of two control groups (diabetic and non-diabetic) and one P. eryngii group. Animals were fed experimental diets for 2 weeks. The values of died and water intake of P. eryngii group were lower than those of diabetic control group. The body weights of both groups after 2 weeks decreased by 18% as compared with initial values. The level of blood glucose decreased significantly by 16.9% in P. eryngii group as compared with diabetic control group, and there was a significant difference in glycosylated hemoglobin (GHb) level between both groups. The levels of total-cholesterol, LDL-cholesterol in plasma and atherosclerotic index were not significantly different between both groups. However the level of HDL-cholesterol increased significantly by 28% in P. eryngii group as compared with diabetic control group. These results suggested that fruiting bodies of P. eryngii exert blood glucose-lowering effect in streptozotocin-induced diabetic rats.

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