• Title/Summary/Keyword: 중선

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Association Study between Per3 Gene Polymorphism and Diurnal Preference (PER3 유전자다형성과 일중선호도의 연관성)

  • Kang, Seung-Gul;Choi, Tae-Young;Yoon, Ho-Kyoung;Park, Young-Min;Kim, Leen;Lee, Heon-Jeong
    • Sleep Medicine and Psychophysiology
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    • v.18 no.1
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    • pp.35-39
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    • 2011
  • Objective: Diurnal preference is an attribute reflecting whether people are alert and preferring to be active either early or late in the day. It also referred to as chronotype or morningness-eveningness trait. The PER3 genes have been known to influence diurnal preference. In this study, we have investigated the associations between the PER3 gene polymorphisms and diurnal preference in a healthy young population, controlling for the social and environmental confounding factors. Methods: The participants in this experiment included 299 unrelated medical college students (M=191, F=108), with a mean age of 22.9 years. Diurnal preference was measured by a single administration of the 13-item Composite Scale for Morningness (CSM). Genotyping of the PER3 VNTR (rs57875989) was performed using polymerase chain reaction. A two-tailed alpha of 0.05 was chosen. Results: The mean${\pm}$SD score on the CSM scale for all subjects was 31.90${\pm}$6.39. There was no significant difference in total CSM score between gender groups, although females showed a trend towards higher morningness score. Although PER3 5R/5R showed the tendency towards high CSM scores, there were no significant differences on CSM scores among genotypes and allele status of PER3 VNTR (rs57875989). Conclusions: We could not confirm that the PER3 VNTR is associated with diurnal preference in a Korean healthy young population. The future studies need to investigate the association between diurnal preference and other polymorphisms of PER3 gene in larger sample of Korean young healthy population.

Aesthetic in Kuk Ak (국악: 부분과 전체)

  • 윤중선
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 1997.04a
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    • pp.14-19
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    • 1997
  • Emotional intelligence and aesthetic aspects of traditional Korean music, Kuk Ak, are investigated in terms of fractal relationship. The exploration of Kuk Ak in the view of an intelligence paradigm will restore the balanced sense of art and science which seeks happiness in life.

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