• Radiation Oncology Journal
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• v.15 no.3
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• pp.243-249
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• 1997

Purpose : In radiation therapy, NTCF is very importart indicator of selecting the optimal treatment plan. In our study, we tried to find out usefullness of NTCP in lung cancer by comparng the incidence of radiation pneumonitis with NTCP. Materials and Methods : From August 1993 to December 1994, thirty six patients with locally advanced non=small cell lung cancer were treated by concurrent chemoradiation therapy. Total dose of radiation therapy was 6480cGy (120cGy, bid) and chemotherapeutlc agents were mitomycin C. vinblastion, cisplatin (2 cycles, 4 weeks interval). We evaluated the development of raniation pneumonitis by CT scan, chest x-rar and clinical symptoms. We used grading system of South Western Oncology Group (SWOG) for radiation pneumanitis. Dose Volume Histograms (DVH) were analyzed for ipsilateral and whole lung, Non uniform DVH was translated to uniform DVH by effective volume method. With these data, we calculated NTCP for ipsilateral and whole lung. Finally we compared the clinical results to NTCP. Results : Eight of thrity six patients developed radiation pneumonitis. Of these 8 patients , 6 had grade I severity and 2 had grade II. The average NTCP value cf the patients who showed radiation pneumonitis was significantly higher than that uf the patients without pneumonitis $(66\%\;vs.\;26.4\%)$. But the results of pulmonary function test was not correlated with NTCP. Conclusion : NTCP of lung is very good indicator for selecting rival treatment planning in lung cancer. According to the results of NTCP, it may be possible to adjust target volume and optimize target dose. In the near future, we are going to anaiyze the effect of hyperfractionation and concurrent chemotherapy in addition to NTCP.

• Proceedings of the Korean Society of Postharvest Science and Technology of Agricultural Products Conference
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• 2003.04a
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• pp.99.2-99
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• 2003

미강은 미곡처리장에서 발생하는 도정부산물이지만 비타민 E, 식이섬유, 오리자놀, 불포화지방산 등 다양한 유효성분들이 함유되어 있고, 콜레스테롤 상승억제효과를 비롯한 여러 가지 생리적 효과를 지니고 있는 것으로 알려지고 있으며, 미국에서는 오래 전부터 미강을 빵, 쿠키, 스낵 등의 baked product에 적용시켜 건강식품을 제조하고 있으나 국내에서는 극히 일부가 미강유 제조에 이용되고 있을 뿐 대부분이 사료로 이용되고 있는 실정이다. 본 연구에서는 쌀의 도정에 의해 영양학적으로 손실된 쌀밥의 영양을 강화하고 쌀밥의 저장성을 향상시킬 목적으로 밥물에 미강 ethanol 추출물을 첨가하여 취반하고 쌀밥의 품질특성 및 저장성을 측정하였다. 미강 5~15g 상당량의 추출물과 지방산에스테르 혼합물의 첨가에 의한 쌀밥의 관능적 특성은 전체적으로 기호도, 맛, 향기 면에서 우수한 평점을 얻었으며 조직감에서도 상당히 높은 평점을 얻었다. 색도, 산도, 총세균수의 측정의 결과에 의한 쌀밥의 저장안정성은 3$0^{\circ}C$에서 저장 중, 대조구에서는 3일만에 변질이 되었으나 미강추출물 첨가구에서.는 4~수일간 변질이 지연되어 첨가 농도에 따라 미강추출물의 쌀밥 저장성이 증가되는 것으로 나타났다. 미강추출물을 표준 토코페놀과 비교하여 DPPH 라디컬 소거능에 의한 항산화 활성은 상당한 수준의 값을 나타냈다. 본 연구를 통해 미강추출물의 기능성 검토와 함께 쌀밥의 풍미개선을 위한 제품개발과 쌀 소비 촉진 효과가 기대된다.

• Korean small business review
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• v.42 no.3
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• pp.245-274
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• 2020

The 4th Industrial Revolution is rapidly changing the business environment and enterprises are required to accelerate various innovative activities for sustainable competitiveness. Recently corporate entrepreneurship is widely spread to organization for establishing innovative corporate culture and stimulating corporate ventures. However, many enterprises are not successful and productive due to lack of readiness of corporate entrepreneruship. Therefore, finding the factors influencing corporate entreprensurship, innovative activities and business performance is a very important research issues. A research model and hypothesis are developed by through literature review to analyze positive effects of corporate entrepreneurship to corporate performance and influential effects of factors such as innovation-based efforts at the organizational level, vision and organizational strategies and innovative operating system to corporate entrepreneurship and business performance. The result of Entrepreneurship Survey with Corporates conducted by Korea Entrepreneurship Foundation in 2017 is used for the research sample. Hypothesis test used 1,326 samples and the structural equation modeling is applied. The results show that corporate entrepreneurship improves innovative idea activity performance and business performance. And, establishing innovative vision and strategies and innovative organizational culture enhances corporate entrepreneurship. In addition, it was confirmed that the innovative operational system has a moderating effect that strengthens the positive influence relationship between corporate entrepreneurship and innovative idea performance. The results of this study have implications for previous research on corporate entrepreneurship in Korea by presenting the relationship between corporate entrepreneurship and business performance and the multilateral relationships between innovative organizational structure and corporate entrepreneurship.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.15 no.3
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• pp.159-174
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• 2020

This study is an empirical study analyzing the effects of positive psychological capital on job burnout. In addition, positive psychological capital played a role in organizational citizenship behavior, and tried to verify the role of organizational citizenship behavior as a black box, or parameter, between job burnout. And then, the sub-factors of organizational citizenship behavior were divided into two: individual-oriented organizational citizenship behavior and organization-oriented organizational citizenship behavior. To this end, a questionnaire survey was conducted for members of small and medium-sized enterprises to compare and analyze the relationship between variables. Positive psychological capital is increasing interest in that it can reduce the job burnout of members and embrace the propensity of young generations represented by millennials because it can improve the effectiveness by developing positive mental states and strengths of the organization. There is a need for research as a keyword. As a result of this study, first, it was found that positive psychological capital of SME(small and medium-sized enterprises) members had a positive effect on organizational citizenship behavior. Second, positive psychological capital was found to have a significant negative effect on job burnout. Third, it was a verification of how positive psychological capital and organizational citizenship behavior affect job burnout. In the relationship between positive psychological capital and job burnout, organization-oriented organizational citizenship behavior was found to play a mediating role. However, it was found that individual-oriented organizational citizenship behaviors among the organizational citizenship behaviors are not valid. In this study, positive psychological capital and job burnout, which have been mainly studied in service workers' emotional workers(crew, nurses, counselors, etc.), nursery teachers, and social workers, were applied to SME members by using the parameters of organizational citizenship behavior. You can put that implication on things. The positive psychological capital and organizational citizenship behavior can be further enhanced through SME members' love for the company, improvement of consideration among employees and resulting organizational commitment and work performance. It could also provide momentum for sustainable management for small and medium-sized enterprises that are relatively short of capital and resources.

• Journal of Life Science
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• v.25 no.10
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• pp.1081-1090
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• 2015

Diabetes has been one of major health risks in industrialized countries. Allium hookeri is a wild herb distributed in India and Myanmar. The root of the plant has been used as food and medicine in Southeast Asia. We investigated Allium hookeri extract improves type 2 diabetes mellitus in C57BL/KSJ db/db obese mouse. C57BL/KSJ db/db obese mouse arise out of Type 2 diabetes and we treated Allium hookeri methanol extract 400 mg/kg (AH 400), 800 mg/kg (AH 800), positive control group (thiazolidinedine;TZDs) were administered orally for 8weeks. AH treated group normalized lipid enzyme system (triglyceride, total cholesterol, HDL-cholesterol and LDL-cholesterol) and serum glucose, HbA1c and plasma insulin level. AH treated group recovered β-cell damage by hyperglycemia and fatty liver disease. AH treated group significantly up regulated expression of Peroxisome proliferator-activated receptor gamma (PPAR-γ), pyruvate dehydrogenase kinase4 (PDK4), Sterol regulatory element-binding protein 1c (SREBP 1) and fork head box O1 (FOX 01) proteins in C57BL/KSJ db/db obese mouse liver. And we found that AH treated group decreased hepatic malondialdehyde formation in C57BL/KSJ db/db obese mouse liver. These results indicate that Allium hookeri methanol extract might be a potential anti-diabetic agent and could be useful in the treatment of type 2 diabetes mellitus.

• Journal of the Korean Society of Radiology
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• v.12 no.3
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• pp.427-433
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• 2018

Because of the expectation of the non-invasive treatment effect, Various studies on the treatment of varicose veins using focused ultrasound are reported. In this study, the bio-tissue phantom and tissue equivalent phantom that can be applied to estimation of ultrasonic varicose veins treatment effect. Each phantom was evaluated for its usefulness by evaluating the acoustic characteristics and the shrinkage rate according to the ultrasonic irradiation. A multi-layer structure phantom with three layers of skin, fat, and muscle was constructed considering the structure of the tissue where the varicose veins occurred. The materials constituting each layer were made to have characteristics similar to human body. In addition, the multi-layered phantoms with blood vessel mimic tube, with bovine blood vessel, and with animal tissue were fabricated. The degree of shrinkage of blood vessel mimic material and vascular tissue according to ultrasonic irradiation was evaluated using B-mode image. As the results of this study, it was thought that the proposed phantom could be used effectively in the evaluation of ultrasonic varicose veins treatment. In addition, it is thought that these phantoms could be applied to the development of varicose vein treatment device using the focused ultrasound and the verification of the therapeutic effect.

• 한국경영정보학회:학술대회논문집
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• 2008.06a
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• pp.680-688
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• 2008

본 연구는 최근 공공부문에 급속히 확산되고 성과 관리시스템을 수용하는데 있어 사용의도에 영향을 미치는 요인들을 실증분석으로 검증하기 위한 연구 이다. 정보시스템 형태로 구현된 BSC(Balanced Scorecard)기반의 성과관리시스템을 수용대상으로 하고 있어 Davis(1986)의 TAM (Technology Acceptance Model)을 기본 틀로 Venkatech et al.(2003)의 UTAUT(the Unified Theory of Acceptance and Use of Technology)를 접목하여 연구모형으로 활용하였다. 설문조사는 BSC시스템을 도입하여 사용 중인 공공부문 기관(회사)을 대상으로 251부의 유효표본을 확보하였다. 구조방정식 모형의 경로분석을 통한 가설검정 결과 13개의 가설 중 9개의 가설이 채택되었다. 교육훈련, 정보시스템 지원, 최고경영자지원, 개인의 혁신성은 노력에 대한 기대에 영향을 미치는 것으로 나타났다. 이는 사용 자들이 새로운 기술 수용에 있어서 보다 쉽게 사용 할 것으로 기대하는데 교육훈련, 정보시스템 지원, 최고경영자지원 등 조직차원의 다양한 지원과 사용자 개인의 혁신성이 요구되는 것으로 해석된다. 성과에 대한 기대의 경로분석 결과 BSC시스템 수용 요인들 중에서 최고경영자지원과 개인의 혁신성만이 영향을 미쳤다. 이러한 결과는 공공부문의 실제 BSC시스템 구축에 대한 사례연구들에서도 지적된 사항이기도 하다. 한편, 노력에 대한 기대는 성과에 대한 기대에 영향을 미치는 것으로 나타났다. 기존의 TAM 관련연구들의 결과를 지지하는 것으로 공공부문 BSC시스템 수용에 있어서도 노력에 대한 기대가 높을수록 성과에 대한 기대가 높은 것을 보여준다.

• Korea journal of population studies
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• v.19 no.1
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• pp.139-159
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• 1996

This study comparatively examines a causal model of employee attatchment which focuses on employee's organizational commitment and intent to stay with an organization. This study is based on two separate studies of employee attachment among teachers : the U.S. case of the Chicago Public Schools (CPS) and the South Korean case of the Seoul Educational District (SED). The main purpose of this study is to replicate in Korea the CPS study. A revised model based on the unique characteristics of Korean teachers is also developed and estimated. The Price Mueller model of employee attachment provides the basic theoretical framework for this study. It includes five general classes of variables : 1) employee responses to work variables : job satisfaction, commitment, and intent to stay; 2) psychological stress variables: role ambiguity, role conflict, work overload, and quality of students; 3) social structural variables: autonomy, routinization, distributive justice, and legitimacy; 4) economic structural variables: pay, job security, promotional opportunities, and job opportunities; and 5) work orientation variables : career commitment, normative commitment, work motivation, affectivity, work values, and met expectations. The data was collected through questionnaire survey and a sample of 649 secondary school teachers in Seoul, South Korea, was included in the final analysis. Covariance structure analysis (LISREL) was used to estimate the causal model. The results indicate that the endogenous variables of job satisfaction and commitment play a considerably less important role than in the U.S. model in mediating the effects of the exogenous variables on intent to stay, and the model fails to explain the majority of the variance in intent to stay. In addition, the new variables added to the revised Korean model do not bave significant effects on intent to stay. The structural characteristics of the employment relationship and labor markets associated with Korean teachers forced mobility and closed external markets - are largely accountable for the major differences between the Korean and the U.S. cases. The study suggests that conceptual and empirical work on what produces employee attachment under these structural constraints needs to receive more attention in future studies.

• Proceedings of the Korean Journal of Food and Nutrition Conference
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• 2000.12a
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• pp.50.2-50
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• 2000

우리나라 전역에 자생하는 소나무의 화분은 건강 식품의 하나로 당질, 단백질, 지질 중 PUFA와 식물성 sterol류, 무기질뿐만 아니라 자연의 항생물질, 효소, 호르몬, 성장물질 및 미지의 유효물질들을 다량 함유하고 있으며, 특히 강장작용, 심장병, 신경장애, 급만성전립선염, 동맥경화, 빈혈 및 간장해독 효과가 밝혀짐에 따라 송화가루에 대한 관심이 증대되고 있다 본 실험에서는 우리밀에 송화가루를 1%,2%,3% 첨가했을 때 제빵적성에 미치는 효과를 알아보기 위하여 반죽의 물성, 호화점도변화, 수분함량, 1차 발효손실률, 굽기 손실률, 색도, 부피 측정, 조직감, 노화도, 주사현미경 관찰, mold-free shelf-life 및 관능검사를 실시해서 최적 배합조건을 찾고자 하였다.

• Proceedings of the Korean Society for Food Science of Animal Resources Conference
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• 2004.05a
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• pp.250-253
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• 2004

본 연구는 Soy Protein Isolate, Egg Albumin 및 Konjac의 보습제(humectants)를 첨가하여 제조한 육포의 이화학적, 미생물학적 및 관능적 특성 등을 조사하기 위하여 실시되었다. 보습제를 첨가한 처리구들은 대조구보다 높은 수분함량 및 제품수율을 나타내었으며, 낮은 puncture force를 나타내어 우수한 조직감을 보였다. 모든 처리구가 저장기간이 경과함에 따라 지질산패도 및 총균수가 증가하였으나 konjac을 첨가한 처리구에서 대조구에 비해 다소 낮은 TBA가를 나타냈었다. 또한 Soy protein isolate와 konjac을 첨가한 처리구가 다른 처리구에 비해 낮은 총균수를 나타내었다. 따라서 보습제 종류별 육포의 품질에 미치는 영향이 다소 차이는 있었지만, 저장성면에서 육포 제조시 보습제로서 konjac 첨가가 보다 유효한 것으로 판단된다.