• Title/Summary/Keyword: 조직병리학

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The Effects of Gamcho on Histamine and Cytokine Production In Murine Asthma Model (감초가 천식모델 생쥐의 plasma내 histamine과 폐조직내 cytokien 생성에 미치는 효과)

  • Song Shang Jin;Bae Han Ho;Park Yang Chun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.3
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    • pp.841-845
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    • 2004
  • This experiment was designed to investigate the effect of Gamcho(Glycyrrhiza uralensis Fisch, GLU) in asthma. We measured histamine, IL-1β, IL-4, 1L-5, IL-6, IL-10, IL-13, in plasma of ovalbumin induced asthmatic mouse. The results were obtained as follows: GLU decreased the proliferation of histamine, IL-1β, IL-4, IL-5, IL-6, IL-13 significantly. GLU increased the proliferation of IL-10 significantly. According to the above results, it is suggested that GLU extract might be useful applied for prevention and treatment of allergic asthma.

Effect of Seed Treatment and Observation of Seeds Infested with Fusarium moniforme by Scanning Electron Microscope (Fusarium moniliforme 감염벼종자의 소독과 주사전자현미경적 조직관찰)

  • Sung Jae Mo;Lee Soon Hyung;Yu Seung Hun;Shin Gwan Chull
    • Korean Journal Plant Pathology
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    • v.1 no.1
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    • pp.51-55
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    • 1985
  • This study was carried out to observe the propagule of Fusarium moniliforme on the surface of rice seed and in the vascular bundle of rice stem by scanning electron microscope. Spore and mycelium of F. moniliforme were observed on the surface of rice seed and in the vascular bundle of rice stem. After seed treatment with Benlate T and Busan 3D, F. moniliforme was not isolated from chaffs, but frequently from brown rice, irrespective of disinfection period.

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Histologic and Cytologic Follow-up in Atypical Squamous Cells of Undetermined Significance(ASCUS) on Cervical Smears (자궁경부도말에서 Atypical Squamous Cells of Undetermined Significance(ASCUS)의 조직학적 및 세포학적인 추적 관찰)

  • Shin, Mi-Kyung
    • The Korean Journal of Cytopathology
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    • v.9 no.1
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    • pp.29-35
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    • 1998
  • In 1988, The Bethesda System for reporting cervical and vaginal cytologic diagnoses was introduced and this was revised in 1991. The new diagnostic category "atypical squamous cells of undetermined significance(ASCUS)" introduced by The Bethesda System is an area of controversy about the diagnostic category, clinical significance and appropriate treatment. A retrospective 2 years and 9 months study(April, 1994-December, 1996) was performed to evaluate the significance of reporting ASCUS on cervical smears. Sixtyseven(1.17%) of 5,730 smears were diagnosed as ASCUS and 21 cases were followed by cervical biopsies and/or endocervical curettages in 4 cases(19%), and repeat cervical smears in 17 cases(81%). Tissue diagnoses were benign in 2 cases and squamous cell carcinoma in situ in 2 cases. Cytologic diagnosis of follow up smear were negative in 14 cases(82.4%) and persistent ASCUS in 3 cases(17.6%).

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Characterization of Pectate Lyase Produced by Erwinia rhapontici During Growth in Host Plant Tissue (Erwinia rhapontici가 기주식물 조직에서 생산한 Pectate Lyase의 특성)

  • 최재을
    • Korean Journal Plant Pathology
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    • v.10 no.3
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    • pp.163-168
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    • 1994
  • Erwinia rhapontici causes soft-rot disease in a number of plants such as rhubarb, onion, hyacinth and garlic. Pectate lyase (Pel) depolymerizes pectin and other polygalacturonates, which is though to play a role in bacterial invasion of plants. Pel activity was not detected in E. rhapontici cultured in a minimal salts medium containing glycerol, polygalacturonate, or citrus pectin as a carbon source. However, when sterilized potato tuber and Chinese cabbage slices were added to minimal salts polygalacturonate (0.5%) medium, E. rhapontici produced pectate lyase enzyme. Also Pel activity was consistently detected from macerated potato tubers, Chinese cabbage leaves, lettuce leaves and celery petioles tissue. Pel in the extract of macerated Chinese cabbage caused by E. rhapontici strain 1, resulted in electrolyte loss, tissue maceration and cell death of potato tuber tissue. These results indicate that E. rhapontici produces pectate lyase only in the presence of non-diffusible plant components, and that this enzyme probably contributes to its pathogenicity.

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Fine Needle Aspiration Cytology of Langerhans' Cell Histiocytosis in the Lymph Node - A Case Report - (림프절의 Langerhans세포 조직구증의 세침흡인 세포 소견 - 1예 보고 -)

  • Kim, Eun-Kyung;Joo, Jong-Eun
    • The Korean Journal of Cytopathology
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    • v.8 no.2
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    • pp.170-173
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    • 1997
  • Langerhans' cell histiocytosis is a relatively rare disorder of children, characterized by abnormal proliferation of Langerhans' cells. It usually presents as multiple osteolytic lesion with lymphadenopathy or cutaneous manifestations. We experienced a case of Langerhans' cell histiocytosis involving bone and lymph node, diagnosed by fine needle aspiration cytology of the lymph node. The patient was a 10-year old girl with left inguinal lymphadenopathy. Fine needle aspiration cytology from the lymph node disclosed very cellular smear consisted of Langerhans' cells, eosinophils and lymphocytes. The Langerhans' cells had eccentric oval to reniform shape nuclei with grooving and abundant pale cytoplasm. The diagnosis was confirmed later by histologic study of bone lesion.

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Fine Needle Aspiration Cytology of Parasitic Infestation in Soft Tissue (연부조직의 기생충 감염의 세포학적 소견)

  • Park, Kyeong-Mee;Ko, Ill-Hyang
    • The Korean Journal of Cytopathology
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    • v.6 no.1
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    • pp.36-40
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    • 1995
  • In the past, parasitic diseases were a major problem in public health in Korea. In recent years, however, nematodiasis that used be prevalent are no longer a serious problem. Instead some cestodiasis, particularly cysticercosis and sparganosis have become comparatively more important in recent years. Parasitic infestation of soft tissue is presented as a subcutaneous nodule or mass with nonspecific clinical manifestations. We experienced 4 cases of parasitic infestation in the soft tissue diagnosed by fine needle aspiration (FNA). Three out of four cases were histologically confirmed, two out of four cases were cysticercosis and one case was confirmed as sparganosis. FNA may be useful in providing a diagnosis in cases of parasitic infestation.

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Cytologic Diagnosis of Malignant Fibrous Histiocytoma in Pleural Fluid - A Case Report (흉막강액에서 진단된 악성 섬유성 조직구종 - 1예 보고 -)

  • Oh, Hwa-Eun;Kim, Yoo-Hoon;Cho, Seong-Jin;Kim, Young-Sik;Kim, In-Sun
    • The Korean Journal of Cytopathology
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    • v.6 no.1
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    • pp.80-83
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    • 1995
  • Malignant fibrous histiocytoma is the most common soft tissue sarcoma of late adult life, but it is rare in the pleura. We recently experienced a case of cytology of malignant fibrous histiocytoma in plural fluid. The smear revealed histiocytic malignant cells, spindle malignant cells and inflammatory cells. The histiocytic cells showed abundant, pale cytoplasm and ovoid, irregular eccentrically-placed nuclei. The spindle cells showed elongated nuclei. Intercellular collagen was also present.

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Bronchial Brushing and Bronchial Washing Cytologic Features of Primary Malignant Fibrous Histiocytoma of the Lung - A Case Report - (폐의 원발성 악성 섬유성 조직구종의 기관지솔질과 기관지세척 검사의 세포학적 소견 - 1예 보고 -)

  • Park, Mi-Ok;Ahn, Wook-Su
    • The Korean Journal of Cytopathology
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    • v.10 no.2
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    • pp.151-155
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    • 1999
  • A case of primary malignant fibrous histiocytoma(MFH) of the lung occurring in a 62-year-old man is presented. After preoperative bronchial blushing and washing cytologic diagnosis of poorly differentiated carcinoma, surgical resection and lymph nodes dissection were performed. Subsequent histologic examination revealed a primary MFH. The diagnosis was confirmed by electron microscopic and immunohistochemical examinations. The review of the bronchial brushing and washing cytologic features disclosed many bipolar and a few unipolar spindle tumor cells with a "comel" configuration, mainly single cells, but also forming loose clusters. The nuclei were elongated and hyperchromatic and contained one or more irregular nucleoli. Scattered bizarre, multinucleated tumor giant cells were also present.

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Phytophthora cryptogea Causing the Foot Rot of Gerbera jamesonii in Korea (Phytophthora cryptogea에 의한 거베라 역병)

  • 지형진;김완규;이상엽;조원대
    • Korean Journal Plant Pathology
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    • v.12 no.3
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    • pp.374-376
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    • 1996
  • 1992년부터 국내 주요 거베라 재배지역에서 Phytophthora속 균에 의한 역병이 발생하였다. 이병주는 뿌리조직이 파괴되어 급격히 시들며 말라죽는데 지제부의 잎자루는 수침상으로 검게 썩는 병징을 나타낸다. 총 47개 균주를 이병주에서 분리하여 균의 형태적, 배양적, 생리적 특성 등을 조사한 결과 모두 Phytophthora cryptogea로 동정되었다. 각 지역에서 수집된 20개 균주중 유성생식형 A1과 A2는 각각 8균주와 4균주였고 8개 균주는 불임성(sterile)이었다. 병원균은 7개 거베라 품종에 모두 강한 병원성을 나타내어 품종간 차이를 관팔할 수 없었다. P. cryptogea는 아직 국내에 기록된 바가 없는 식물병원균으로 거베라 역병균으로 처음 보고한다.

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Histopathology of dermatitis verrucosa in holstein dairy cattle (홀스타인 젖소의 우상피부염 (dermatitis verrucosa) 의 병리조직)

  • Jean, Young-Hwa;Kim, Jae-Hoon;Jeong, Soon-Wuk;Yoon, Suk-Jung;Choi, Sang-Ho
    • Korean Journal of Veterinary Pathology
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    • v.3 no.1
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    • pp.65-68
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    • 1999
  • Clinically, three holstein dairy cattle showed the inappetence and decrease of milk production with severe lameness and pain. Grossly, strawberry-like proliferation of the skin between the heel bulbs were observed 4${\times}$5${\times}$1.5cm in size. Histopathologically, severe hyperplasia of epidermis, parakeratotic hyperkeratosis and multifocal ulceration of cornified cell layer, acanthosis, spongiosis of prickle cell layer and irregular arrangement of basal cell layer were seen. And focally observed the lesions of necrotic vasculitis, infiltration of inflammatory cells, congestion and hemorrhage. Spirochete bacteria were found in necrotic and outer proliferated epidermal cells by Levaditi's silver stain. Clinical and pathological findings were consistent with dermatitis verrucosa.

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