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Bilolgical Activities of Conjugated Linoleic Acid (CLA) and Animal Products (Conjugated Linoleic Acid (CLA)의 생리활성과 축산식품)

  • Hur, S.J.;Lee, J.I.;Ha, Y.L.;Park, G.B.;Joo, S.T.
    • Journal of Animal Science and Technology
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    • v.44 no.4
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    • pp.427-442
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    • 2002
  • Conjugated linoleic acid(CLA) is a collective term for a group of positional (c8, c10; c9, c11; c10, c12, and c11, c13) and geometric(cis,cis; cis,trans; trans,cis; and trans,trans) isomers of octadecadienoic acid (linoleic acid) with conjugated double bond system. CLA has been shown to have a variety of biological effects. Major effects of CLA on health, such as anti-cancer, anti-oxidation, anti-atherosclerosis and improving immuno-responses, might be derived or partially derived from the alternated lipid metabolism after CLA feeding. Most of studies on the effect of CLA on fat metabolism are concentrated on rats, mice, pigs and other mammals. The CLA inhibited carcinogen-induced neoplasia in several animal models and inhibited the proliferation of human malignant melanoma, colorectal and breast cancer cells and CLA reduced the atherosclerosis. Several studies have determined the antioxidant property of CLA; however, the property still remains controversial. Some of the studies have shown that CLA acted as an antioxidant, whereas some other studies have demonstrated that CLA might be a prooxidant. Several studies suggested that CLA could reduce fat accumulation in mammals. CLA was suggested to promote muscle growth and reduce fat deposition in mouse, and improve feed efficiency in rats. CLA has been shown to inhibit the activity of stearoyl-CoA reductase. CLA also reduced the content of arachidonic acid. Since arachidonic acid, and eicosapentaenoic acid (EPA) and docosahexenoic acid (DHA) are synthesized by different pathways, reducing the synthesis of arachidonic acid may not mean reducing that of EPA and DHA. Many sutdies have been shown biological effects of CLA. Therefore, further research is needed to answer the following questions: 1) how to synthesize the new CLA by new methods, 2) why CLA has shown biological effects, 3) how to increase CLA effects in animal products.

The Comparison between Single Shot Turbo Spin Echo and B-FFE (Balanced Turbo Field-echo) in the Differentiation of Focal Liver Lesions (국소 간병변 감별에서 단발고속스핀에코 기법과 균형항정상 태세차를 이용한 고속영역 기법간의 비교)

  • Kim, Young-Chul;Kim, Myeong-Jin;Cha, Seung-Whan;Chung, Yong-Eun;Han, Kwang-Hyup;Choi, Jin-Sub
    • Investigative Magnetic Resonance Imaging
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    • v.11 no.1
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    • pp.39-48
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    • 2007
  • Purpose : To determine the diagnostic accuracy of four different sequences : moderately T2 weighted, two heavily T2-weighted single shot turbo spin-echo sequence and breath-hold axial-2D balanced turbo field-echo sequence(bFFE) for characterization of focal lesions. Materials and Methods : During the 3-month period between June and August 2005, seventy-six patients were proved to have ninety-three focal hepatic lesions on MR imaging. The patients consisted of 49 men and 27 women (age range, 15-75 years; mean age, 56.23 years). All MR images were acquired on a 1.5-T MR using the following sequences: 1. A breath-hold axial T2-weighted single shot turbo spin-echo sequence, 2. a breath-hold axial-2D balanced turbo field-echo sequence. Two radiologists performed quantitative analysis. Another radiologist measured the lesion-to-liver contrast-to-noise ratio at the region-of-interest in the four sequences. Results : There was no significant difference in inter-observer variability between the four sequences. The accuracy for both cyst and malignancy of moderate T2 weighted MRI (echo time: 80 msec) was also highest. There was significant difference for lesion characterization between moderate T2 weighted MRI and balanced steady state procession (p-value: 0.004) in the second reader. For longer echo time, the CNR of cystic lesions were markedly increased in comparison to lesions of other component. Conclusion : The accuracy and inter-observer variability of single shot turbo spin echo T2 weighted sequence was higher than bFFE. Although there was no statically significant difference, moderate T2 weighted MRI (echo time: 80 msec) was more accurate than heavily T2 weighted sequence (echo time: 300 msec). If the results for lesion characterization is equivocal in TE 80, the addition of heavily T2 weighted MRI (echo time: 180 msec) can be helpful.

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Analysis of Quality State for Gochujang Produced by Regional Rural Families (지역별 농가 생산 고추장의 품질 현황 분석)

  • Lee, Seul;Yoo, Seon Mi;Park, Bo Ram;Han, Hye Min;Kim, Ha Yun
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.43 no.7
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    • pp.1088-1094
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    • 2014
  • This study investigated the quality properties of glutinous rice Gochujang produced by regional rural families in order to determine the present state of quality of traditional Gochujang. A total of 80 Gochujang samples were collected from nationwide rural families and their physicochemical characteristics were analyzed. Based on regional mean, ranges of moisture contents, pH, acidity, crude protein contents, and salinity of Gochujang were $44.31{\pm}5.73%{\sim}50.50{\pm}5.65%$, $4.59{\pm}0.36{\sim}4.79{\pm}0.15$, $1.18{\pm}0.22%{\sim}1.54{\pm}0.36%$, $5.28{\pm}0.90%{\sim}6.93{\pm}.09%$, and $5.55{\pm}0.85%{\sim}8.29{\pm}1.19%$, respectively. The mean contents of amino type N, reducing sugars, and capsaicinoids were $488.81{\pm}79.74mg%{\sim}715.16{\pm}78.09mg%$, $22.32{\pm}9.43%{\sim}28.61{\pm}8.80%$, and $44.31{\pm}18.71mg/kg{\sim}65.15{\pm}47.98mg/kg$, respectively, and differences were significant among the Gochujang samples. Hunter color values (L, a, and b) of Gochujang were $4.84{\pm}3.08$, $21.26{\pm}10.53$, and $8.20{\pm}5.91$, respectively, and the range of viscosity was $31,511{\pm}11,764{\sim}72,923{\pm}32,555$ cP. The acidity, salinity, moisture, crude protein, and amino type N contents of Gochujang produced from the Gangwon-do and Gyeonggi-do areas were significantly higher than those of other regions. According to principal component analysis of the physicochemical characteristics of Gochujang produced by rural families, the salinity, acidity, moisture, crude protein, and amino type N contents were strong characteristics of Gochujang produced by Gangwon-do and Gyeonggi-do. These results indicate that traditional Gochujang produced by rural families shows various quality properties and regional differences in physicochemical characteristics.

Antibacterial Activity of Platycarya strobilacea Extract and Stability of the Extract-containing Cream (굴피나무 추출물의 항균 활성 및 추출물을 함유한 크림의 안정성 분석)

  • Yang, Hee-Jung;Kim, Eun-Hee;Kang, Sung-Tae;Park, Soo-Nam
    • Microbiology and Biotechnology Letters
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    • v.37 no.2
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    • pp.170-175
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    • 2009
  • The extract of Platycarya strobilacea is known to possess a wide range of pharmacological activities including anti-inflammatory, anti-fungal, and anti-cancer properties. We have reported that the ethyl acetate fraction of Platycarya strobilacea (PS-ET fraction) has high potential as an antioxidant agent (J. Soc. Cosmet. Scientists Korea 34(4) 275, 2008). In this study, antibacterial activity of the fraction and stability of the cream containing 0.2% PS-ET fraction were investigated for the application to cosmetics. Antibacterial activity of PS-ET fraction against various skin pathogenic bacteria (Propionibacterium acnes, Staphylococcus aureus, and Pityrosporum ovale) was measured by minimum inhibitory concentration (MIC). MIC values of PS-ET fraction on P. acnes, S. aureus, and P. ovale were 0.13%, 0.06% and 0.25%, respectively. The results showed that the antibacterial activity of the fraction was the highest in the S. aureus. For the stability evaluation, pH and viscosity of the cream containing 0.2% PS-ET fraction were measured. The results showed that pH changes of the cream containing PS-ET fraction was lower than the control cream without PS-ET fraction. And the PS-ET fraction could repress the decrease of viscosity of the cream against sunlight treatment. These results suggest that the fraction of Platycarya strobilacea has high potential as bactericide against the skin pathogenic bacteria and could be added to improve the stability of cosmetic products.

The Effect of Use of Nutrition Labelling on Knowledge and Perception of Nutrition Labelling, and Awareness of Nutrition Labelling Usefulness with among College Students (대학생의 영양표시 확인 여부에 따른 영양표시에 대한 지식, 인식 및 유용성 자각 비교)

  • Lee, Kyoung-Ae;Lee, Hyun-Jin;Park, Eun-Ju
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.39 no.2
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    • pp.253-266
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    • 2010
  • This study describes the prevalence of nutrition labelling use and its association with demographic factors, knowledge and perception of nutrition labelling, and awareness of nutrition labelling usefulness among 282 college students, aged 21~23 years, in Busan Gyeongnam area. The subjects consisted of 150 of male (53.2%) and 132 of female (46.8%) students. 31.3% of male students and 50% of female students reported reading nutrition labelling always or usually, while 34.7% of male and 13.6% of female subjects reported that they don't use nutrition labelling. Although most of the subjects perceived the need of nutrition labelling, their knowledge and understanding of nutrition labelling and their awareness of nutrition labelling usefulness were not enough to apply the information from the nutrition labelling in their daily life, even in the subjects who reported reading nutrition labelling always or usually. This statement might be one of the reasons why there were no significant differences among the groups divided by nutrition labelling use in regards to the dietary habit or snack eating habit in this study. Therefore, a practical nutrition education program on nutrition labelling should be provided for the college students to increase nutrition labelling use and to apply the information from nutrition labelling in their daily life in order to maintain healthy dietary habit.

A Study on the Determination of Radionuclide Concentrations in Animal Feedstuffs for Use Following a Nuclear Emergency (원자력 비상시 가축의 사료로 이용을 위한 사료내 방사성 핵종농도 결정에 대한 연구)

  • Hwang, Won-Tae;Kim, Eun-Han;Suh, Kyung-Suk;Choi, Young-Gil;Han, Moon-Hee
    • Journal of Radiation Protection and Research
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    • v.26 no.2
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    • pp.87-91
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    • 2001
  • The optimized derived intervention levels for animal products were evaluated based on cost-benefit analysis. From these results, the radionuclide concentrations in animal feedstuffs for use were derived. It was shown that radionuclide concentrations in animal feedstuffs for use depend strongly on animal products, radionuclides and feeding period (period from the starting time to be led with contaminated feedstuffs to production time of animal products). In case of feedstuffs contaminated with long-lived radionuclides ($^{l37}Cs,\;^{90}Sr$), the feedstuffs with lower contamination should be supplied to animals with increase of feeding period due to the bioaccumulation of radionuclides. While, in case of feedstuffs contaminated with short-lived radionuclides ($^{131}I$), the feeding of higher contaminated feedstuffs was possible with increase of feeding period due to radionuclide decay. It was shown that $^{137}Cs$ concentration in animal feedstuffs lot use was lower than $^{90}Sr$ concentration. It is primarily, due to the higher feed-animal product transfer factor of $^{137}Cs$.

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Changes in Korean Consumer's Perception and Attitudes toward Genetically-modified Foods (우리나라 국민의 유전자재조합식품에 대한 인지도 및 수용도 변화)

  • Kwon, Sun-Hyang;Chung, In-Shick;Choi, Mee-Kyung;Chae, Kyung-Yun;Kyung, Kyu-Hang
    • Journal of Food Hygiene and Safety
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    • v.23 no.3
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    • pp.182-190
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    • 2008
  • A survey on consumer's awareness and perception toward genetically-modified(GM) foods was conducted on 2110 random samples of Korean consumers. More than 65% of the respondents were exposed to some information related to GM foods. The respondents answered that the greatest benefit of the development of GM foods is remedy of potential food shortages in the future. More than 90% of Korean consumers wanted GM foods to be labeled as such. More than 50% of the respondents would not buy until they know more about GM foods. Only 35.8% of Korean consumers were found to know that food items originating from plants contained genes. More consumers responded that they would not buy herbicide-resistant GM soybean but buy vitamin-enriched GM soybean. Many Korean consumers' decision of acceptance or rejection of GM foods depend not on the basis of biotechnology, but on the basis of the degree of benefit to the consumers. Only 6.4% of Korean consumers responded that GM foods were the greatest threat to the safety of Korean foods. The perception of Korean consumers on GM foods has not changed significantly during the past 5 years.

Study on the Compared between u-Learning and e-Learning based SCORM (SCORM 기반 u-Learning과 e-Learning 비교연구)

  • Choi, Sung;Ryu, Gab-Sang
    • Proceedings of the Korea Society of Information Technology Applications Conference
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    • 2006.06a
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    • pp.495-505
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    • 2006
  • IT기술기반 교육시스템은 인터넷 등장 이전에도 가능성을 인정받아 지속적으로 개발되어 온 분야이며, 교육공학과의 연계로 지식 전날의 이론체계로 각광을 받고 있다. 사이버교유도 인터넷이전부터 다양한 통신방법을 응용하여 개발되었고, 최근 인터넷을 통하여 사이버 교육시스템은 완벽한 기술기반을 갖추게 되였다. 그러나 IT기술의 급격한 변화로 사이버교육시스템은 계속하여 신기술 변화에 적용해야만 한다. 현재 정보통신기술의 변화는 방송 통신망의 융합, 브로드 밴드 네트워킹, 스마트 디바이스의 다양화, 멀티미디어 기술의 고도화로 요약된다. 이 기술의 종합한 작용으로 유비쿼터스 사회의 기반으로 진화되고 있다. 그래서 e-Learning 분야도 기존 인터넷기반 시스템과는 달리 차세대 온라인교육시스템으로 친화되고 있다. IT융합가술 기반의 온라인 교육시스템은 각종 국제표준단체에서 표준안이 제시되고 있다. e-Learning 시스템이란 선기술 기반을 반영한 표준기술을 사용하는 온라인교육시스템을 포괄하는 개념이다. 본 연구에서는 e-Learning 시스템과 유비쿼터스 기술을 반영한 e-Learning을 비교하였다. 그리고 u-Learning 시스템의 기술정립과 EOD(Education On Demand) 시스템에 대하여 연구하였다. 1. u-Learning 정의 정보산업분야를 비롯한 문화, 교육 등 모든 분야에서 유비퀴터스라는 수식어가 붙어 다니고 있다. e- Learning 교육 업계에 따르면 10년 후에는 유비쿼터스는 대중화가 될 것이며, 부가가치 규모는 100조 원에 이를 것으로 추정된다. 그래서 교육산업도 주변 환경이 아날로그 방식에서 IT 기반에 의한 디지털 환경으로 변화되고 있다. 또한 e러닝, T러닝, m러닝, u러닝 등의 용어가 생성되고 있다.키지에어컨에서 사용되고 있는 밀폐형 압축기에 대해서 그림 2에서 나타내고 있는 냉방능력 10tons(120,000Btu/h) 이하를 중심으로 상기의 최근 기술 동향을 간략하게 소개하고자 한다.질표준의 지표성분으로 간주되는 진세노사이드의 절대함량과 그 성분조성 차이에 따른 임상효과의 차별성이 있는지에 대한 검토와, 특히 최근 실험적으로 밝혀지고 있는 사포닌 성분의 장내 세균에 의한 생물전환체의 인체 실험을 통한 효과 검정이 필요하다. 나아가서는 적정 복용량의 설정과 이와 관련되는 생체내 동태 및 생체이용율(bioavilability)에 관한 정보가 거의 없으므로 이것도 금후 검토해야 할 과제로 사료된다. 인삼은 전통약물로서 오랜 역사성과 그동안의 연구결과에 의한 과학성을 가지고 있으므로 건강유지와 병의 예방 및 회복촉진을 위한 보조요법제 또는 기능성 식품으로써의 유용성이 있는 것으로 판단된다. 앞으로 인삼의 활용성 증대를 위해서는 보다 과학적인 임상평가에 의한 안전성 및 유효성 입증과 제품의 엄격한 품질관리의 필요성이 더욱 강조되어야 할 것이다.xyl radical 생성 억제 효과를 보여 주었다. 본 실험을 통하여 BHT 를 제외하고 전반적으로 세포 수준에서의 oxidative stress 에 대한 억제 효과를 확인해 볼 수 있었으며 특히 수용성 항산화제들에서 두드러진 효과를 보여 주었다. 제공하여 내수기반 확충에도 노력해야 할 것 이다.있었다., 인삼이 성장될 때 부분적인 영양상태의 불충분이나 기후 등에 따른 영향을 받을 수 있기 때문에 앞으로 이에 대한 많은 연구가 이루어져야할 것으로 판단된다.태에도 불구하고 [-wh]의미의 겹의문사는 병렬적 관계의 합성어가 아니라 내부구조를 지니지 않은 단순한 단어(minimal $X^{0}$<

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Qualitative Research on Mothers' Stress Level of Meal Preparation and Change of Food Consumption Pattern in Context of COVID-19 (코로나19 이후 가정 내 어머니의 식사준비 스트레스와 먹거리 소비패턴 변화에 관한 질적연구)

  • Lee, Yoonsun;Ryu, Sihyun
    • The Journal of the Korea Contents Association
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    • v.22 no.2
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    • pp.695-709
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    • 2022
  • This study examined the mothers' stress level as it related to meal preparation and a change in food consumption during the Covid-19 pandemic. I asked mothers about the difficulties related to meal preparation, changes in food consumption, and their interest in food and health information using in-depth research methods. As a result, food delivery and online food consumption have markedly expanded as eating out has decreased. Mothers tried to serve fresh food at home because they perceived delivery food as unhealthy. They stick to it more vigorously with their younger children. As the result of analysis on determinants of food consumption, their interest in organic food is higher when mothers' ages are younger with higher income. However, mothers with a low level of education tend to be uninterested in it. Therefore, the ages of the children and mothers, household income, and education levels all had an effect on food consumption behaviors.

A Study on How the Functional Difference of User Interface Design Layout Affects User Experience. - Focusing on the F-layout and Z-layout - (웹사이트에서 유저인터페이스디자인 레이아웃의 기능적 차이가 사용자 경험에 미치는 영향 연구 - F레이아웃과 Z레이아웃을 중심으로 -)

  • Lee, Moon Hyung;Park, Il Kwun
    • Design Convergence Study
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    • v.14 no.4
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    • pp.181-192
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    • 2015
  • The layout includes various functions not only arrangement, connection, division of information but also affordance and information recognition as the important element that determine the whole structure of information. Recently, the layout of web interface design was gradually changing from the concept of the original Z-layout to F-layout, whereas, it is being changed again into the split layout as the transform of Z-layout. However, there can be lack of grounds as to the reason of the change of layout. Therefore, it needs to study on how the functional difference between the F-layout and Z-layout affects user experience. In this study, we conduct the study on the effect of each layout type on the user experience focusing on the product description of web-page by user test. The user test have shown that the user has better feeling on the split layout based on the Z-layout than F-layout. The Z-layout also has more advantages on the formation of the favorable attitude of user in efficiency, accessibility and concentration. This result is consistent with the trend of web-design to change into the split layout based on the Z-layout and we provided the objective reasons for the effective web-design layout by user test.