• The Korean Journal of Pesticide Science
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• v.20 no.1
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• pp.35-40
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• 2016

Recently, bacterial angular leaf spot disease, caused by Xanthomonas fragariae, causes severe damage in strawberry production and its' export to other countries, since the pathogen has been classified as an A2 quarantine pathogen. Typical the Angular Leaf Spot (ALS) disease represent that water-soaked angular spots symptoms, bacteria ooze exudate under relatively high humidity condition and later the spot become reddish brown on the leaf surface. The pathogen disseminated by irrigation water, infected mother plant and farmer's hand. In this study, we reported that rubbing inoculation method showed more effective in the pathogen dissemination than infiltration with needles, regardless the strawberry cultivars. Additionally, Dichloroisocyanurate (NaDCC) treatment in commercial strawberry fields provided reliable efficiency to reduce the bacterial angular leaf spot disease incidency and severity.

• Tuberculosis and Respiratory Diseases
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• v.57 no.2
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• pp.101-117
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• 2004

현증 결핵환자가 감소하고, 면역억제환자가 증가하고 있는 국내 추세에서 잠복결핵(latent tuberculosis)의 진단 및 치료 지침이 필요한 실정이다. 그러나 결핵의 유병률, 발생률 그리고 비씨지 접종률 등이 외국과 다른 국내의 현실에서 현증이 없는 잠복결핵의 진단 및 치료에 대한 방침은 필연적으로 외국과 다를 수 밖에 없으며, 현 시점에 국내에서 이에 대한 자료가 불충분하여 국내의 환경에 적합한 근거 중심의 지침을 설정하기는 어려운 상황이다. 그러나 결핵의 기본 병태 생리를 근거로 하여 최소한 결핵균 감염 이후 결핵 발병의 위험성이 높은 대상 환자에서는 잠복결핵 진단을 위한 검사를 시행하여 치료 여부를 결정하여야 한다. 고위험군은 사람면역결핍바이러스(human immunodeficiency virus, HIV) 감염자, 장기이식환자, 면역억제제를 장기간 사용하는 환자, 6세 이하의 소아 중 최근 전염성 결핵환자 접촉자 등을 우선적으로 고려해야 한다. 미국은 발병 위험도의 고, 중, 저에 따라 투베르쿨린 검사(tuberculin skin test, Mantoux test)의 양성기준을 달리 하여 잠복결핵을 진단하고 있으나, 국내에는 아직 이에 대한 자료가 부족하므로 발병의 위험이 높은 상기 고위험군을 대상으로 하여 PPD RT-23 2TU (Tuberculin unit)를 이용한 피부반응검사에서 10mm이상의 경결(induration)이 생성되는 경우를 양성으로 정하고 추후 연구 결과에 따라 재조정이 필요하다. 그 동안은 투베르쿨린 검사 결과 5-10 mm 사이의 경결반응을 보이는 면역억제 환자에 대하여는 개별적으로 의사의 판단에 따라 잠복결핵의 진단 및 치료 여부를 결정한다. 그러나 면역억제제를 사용하는 등 결핵 발병의 고위험군에서는 피부반응검사상 음성이라도 과거 결핵 치료력이 없이 흉부사진상 명백하게 과거에 결핵을 앓은 흉터가 남아있는 경우(석회화된 1차 결핵 소견은 제외)에는 잠복결핵의 치료를 시행한다. 상기 잠복결핵의 진단 및 검사의 적응증은 최소한 시행하여야 할 경우를 나열한 것으로 이외의 환자에 대하여는 환경 및 대상에 따라 개별화되어야 한다. 치료제로는 isoniazid (INH) 9개월 매일 치료(최소 한 6개월 이상, HIV양성 환자인 경우는 9개월), rifa-mpicin (RFP) 4개월 치료 및 INH/RFP 3개월 매일 치료를 시행할 수 있다. 상기 치료가 어려운 경우에는 RFP/pyrazinamide (PZA) 2개월 매일 치료를 고려할 수 있으나 중증 간독성의 가능성에 대한 철저한 교육 및 추적검사가 필요하다. 향후 국내 환경의 변화 및 연구결과에 따라 추후 부족한 부분에 대한 지침의 재정립이 필요하다.

• Korean Security Journal
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• no.46
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• pp.171-187
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• 2016

Human trafficking is a booming underground business and is the fastest growing and criminal activity in today's society. The use of coercion or fraud marks the territory of trafficking. Most people trafficked suffer constant threats, violence, and forced acts while imprisoned by their traffickers. Such human trafficking entails significant problems not only for the victims but also for the economies and community health. Large corporations overseas have also been known to partake in the sex slave industry. Another hidden cost to the global economy is the cost of law enforcement and anti-trafficking measures being implemented. Further, sex Trafficking carries many potential health consequences, one of the biggest risks is HIV infection. That means, sex trafficking is an engine of the global AIDS epidemic with one study portraying nearly fifty six percent of all sex slaves having HIV or AIDS. Therefore, many of people are being infected with HIV and many other diseases every day through contact with the sex slave industry costing millions to society and the global economy. in this study, the author presents a case study of trafficking against Nepalese women. Nepalese women being trafficked are found to have a high prevalence of HIV infection. In conclusion and discussion, a few of solutions needed to be addressed for controling human trafficking for sex slavery suggested.

• Proceedings of the KAIS Fall Conference
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• 2009.05a
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• pp.114-118
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• 2009

주요 일간지와 KBS 1 9시 뉴스에서 다루고 있는 건강관련 기사의 내용을 분석하여, 건강관련 정보의 경향을 파악하여, 건강 예보제 실시를 위한 현황 분석을 위해 본 연구를 실시하였다. 1. 일간지 건강정보 내용분석 결과요약: 기사 보도 분야에서는 생활건강(47.8%), 사회(14.6%), 종합(7.7%), 국제(4.7%), 경제(1.5%) 순이었고, 3/4분기에서만 국제와 경제 분야가 종합분야 보다 많이 보도 되었으며, 기타 분야가 22.9%로 많은 비율을 차지하였다. 건강정보를 대상 성별별로 분류 하였을 시 남녀 모두에 해당되는 자료가 대다수였고(87.9%), 여성이 대상인 정보(8.0%)가 남성(4.1%)보다 많았으며, 생애 주기별 대상으로 분류 하였을 시에 역시 특별히 구분되지 않은 모든 연령층에 해당 정보가 가장 많았고(60.8%), 성인(19.8%), 학동기 어린이(7.3%), 청소년 (4.9%), 노인(4.9%), 영유아(3.3%) 순이었다. 일간지별 기사의 주제를 조사한 결과 두 일간지의 총합은 병의 원인 및 위험인자(15.5%)가 가장 많이 보도 되었는데, 조선일보는 건강증진, 치료 및 술기, 투약, 기타의 순이었고, 한겨레신문은 건강증진, 행정, 치료 및 술기, 투약 순이었으며 각 주제별로 분기별로 약간의 차이를 나타내었다. 예측성에 관한 내용분석을 보면 예보성은 있는 경우(76.2%)가 없는 경우보다 많았고, 예보성의 정보는 알림성, 예측성, 행사성의 순이었고 예측성의 경우 건강형태가 가장 많았으나 한겨레 신문의 경우 기타에 속하는 경우가 가장 많았다. 사 ICD-10 체계, 21대 분류로 질병에 관한 기사를 분류한 결과 신생물(14.5%), 특정 감염성 및 기생충성 질환(13.6%), 정신 및 행동장애(9.5%)의 순이었으며 두 일간지간의 차이를 보였다. 2. TV 뉴스 건강정보 내용분석 결과요약: 건강정보의 대상 특징 성별은 모두 해당되는 경우가 265회 중 238회 (89.8%)로 가장 많았고, 생애주기별 대상으로 보면 모든 연령층에 해당 되는 것이 154회(58.1%)로 가장 많았다. 건강정보의 주제에 대해서 조사한 결과 병의 원인 및 위험인자가 73회(27.5%), 역학(역학조사 및 보도성)이 64회 (24.2%), 행정이 30회(11.3%), 증상 및 호소가 27회(10.2%) 등의 빈도순으로 조사 되었다. 건강정보의 내용의 분야를 보면 대분류로는 질병관리 분야가 102회(38.5%), 보건의료제도 및 행정 분야가 52회(19.6%), 보건행태 및 기타 42회(15.8%), 생활환경분야 39회(14.7%)의 빈도순으로 나타났다. 건강정보 내용을 질병의 분류 ICD-10 체계로 분석한 결과는 특정감염성 및 기생충성 질환 48회(26.8%), 소화기계의 질환, 손산, 중독 및 외인에 의한 특정기타 결과, 건강상태 및 보건서비스 접촉에 주는 요인 등의 빈도순으로 조사되었다.

• Journal of Life Science
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• v.17 no.1 s.81
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• pp.31-38
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• 2007

Infection with virulent or attenuated Salmonella typhimuriumhas known to induce reduction in proliferative responses of spleen cells. We investigated a role of lipid A from S. typhimurium, a B cell mitogen, on proliferation of spleen cells by T cell mitogens such as concanavaline A and phytohemagglutinin under in vitro and ex vivo conditions. Lipid A alone induced proliferation of spleen cells in vitroin a dose-dependent manner. However, subsequent treatment of concanavaline A or phytohemagglutin in after lipid A treatment induced proliferation suppression of murine spleen cells in vitro and ex vivo. Removal of macrophages from spleen cells, which were obtained from a lipid A-injected mouse, restored proliferation by concanavaline A and phytohemagglutinin, indicating that macrophages appeared to play a role in lipid A-induced suppression. Secreted molecules from macrophages did not accounted for the suppression because suppressive effect was not achieved when the supernatant from macrophage-containing spleen cell culture was conditoned to macrophage-depleted spleen cell culture. Co-culture of spleen cells from lipid A-treated and - untreated mice showed proliferation suppression as increasing cell numbers of lipid A-treated mouse. These data suggested that the cell-to-cell contact of macrophage with splenic lymphocyte cells is responsible for immune responses against lipid A, which is applicable to the case of human S. typhi infection.

• Journal of Korean Society of Archives and Records Management
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• v.16 no.2
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• pp.173-183
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• 2016

Fungi are a major cause of cultural and biological degradation in museum storages and archives libraries. In addition, fungi produce toxins and can cause skin allergies. In particular, fungi coming into contact with the skin through the hands of administrators dealing with cultural properties, archives, and books can lead to secondary infections. To prevent this, applying hand sanitizer, which is readily available in the market, is recommended. However, such hand sanitizer can effectively disinfect against bacteria but not fungi. As such, researching for an alternative is required. In this study, we developed a hand sanitizer composed of active ingredients - geranial, cineol, menthol, and Chamaecyparis obtusa - and performed a disinfection test, which targets 10 kinds of species (Alternaria citrimacularis, Alternaria consortialis, Aspergillus niger, Aspergillus versicolor, Cladosporium sphaerospermum, Coniothyrium aleurites, Penicillium brevicompactum, Penicillium corylophilum, Penicillium paneum, and Penicillium polonicum), of fungi investigated in museums and libraries. It was then confirmed to exhibit excellent disinfecting effects. Thus, this hand sanitizer is expected to prevent skin diseases and secondary infections in administrators dealing with cultural properties, archives, and books.

• Journal of the Korea Convergence Society
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• v.10 no.10
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• pp.75-80
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• 2019

During the medical ultrasound exercise at school, we randomly select parts of the ultrasound device and areas with the most contact in the abdominal phantom to detect bacteria that are above the probe and determine the number of pathogens. I want to find out. The experimental method was rubbed 20 times with the sterilized cotton swab for sterilization and then smeared on Lysogeny broth (LB) agar, put into the incubator and incubated for 48 hours, and the colony forming unit (CFU) count was measured. The bacterial distribution of probe handle and abdominal phantom was evaluated by evaluation. As a result, the CFU value is the lens was $3.0{\pm}0.87$, print button was $5.5{\pm}1.06$, freeze button was $8.0{\pm}4.95$, phantom was $20.0{\pm}2.78$, line was $23.5{\pm}2.50$, and probe handle was measured as $35.3{\pm}10.75$. In this study, it is expected that attention to infection control of equipment during practice during medical ultrasound practice can be highlighted and further contributed to the reduction of bacterial infection rate of ultrasound devices.

• Knowledge Management Research
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• v.22 no.2
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• pp.227-246
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• 2021

In the context of the global pandemic caused by COVID-19, emergency alert text messages can violate the privacy of confirmed corona positive cases. This study used conjoint analysis to identify the essential information factors and the privacy invasion information factors of local government initiated safety notices. As a result of this study, we found eight essential information factors, including all routes of the confirmed case and ten privacy invasion factors of safety notices. In addition, we found that there is a similarity between the combinations of information perceived to be the most essential and perceived as the most significant privacy invasion; both combinations include the confirmed case's personal and route information. This study ultimately tried to suggest a way to lower the concern about privacy invasion of the confirmed cases without damaging the emergency alert text messages' essential information. We expect that this study will provide researchers and policymakers interested in disaster communication with valuable theoretical and practical implications.

• Pediatric Infection and Vaccine
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• v.12 no.2
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• pp.157-165
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• 2005

Purpose : Children occupy a large proportion of burn victims. So we want to aid to pediatric burn care through the understanding of the bacterial distribution in burn wounds and antibiotic susceptibility against isolated microorganisms from burn wounds. Methods : We analysed the medical records of 213 pediatric burn patients(0~15 years), 406 samples that grew bacteria in burn wound sites. Results : Of the total 213 patients, male were 59.6% and female were 40.4%. Scalding burn was the most common(78.4%), flame burn was the second(16.4%). Pathogens were isolated in 406 samples. The most common was Pseudomonas aeruginosa(58.1%). Next were Enterococcus species, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus species, Acinetobacter species. P. aeruginosa was resistant to trimethoprim-sulfamethoxazole in 100%, cephalothin in 98.1%, ampicillin-sulbactam in 96.2%, ampicillin in 95.3%, ceftriaxone in 95.2%, tobramycin in 93.7%, cefoperazone in 68.9%, ceftazidime in 67.7%. Enterococcus species were resistant to tetracycline in 63.9%, streptomycin in 45.5%, gentamicin in 36.1%, penicillin G in 13.7%. S. aureus was resistant to gentamicin in 89.7%, tetracycline in 86.2%, ciprofloxacin in 86.2%, penicillin G in 84.3%, oxacillin in 78.4%, erythromycin in 76.5%. Acinetobacter species were resistant to ampicillin-sulbactam in 100%, gentamicin in 85.7%, ampicillin in 83.3%, piperacillin in 61.5%. Conclusion : P. aeruginosa was highly resistant to drugs like cefoperazone in 68.9%, ceftazidime 67.7%. S. aureus was highly resistant to penicillin G in 84.3%, oxacillin in 25.9 %, but none to vancomycin in 0%, teicoplanin in 2.2%. According to the study, Acinetobacter species turned out to be multi-resistant strains, so careful attention must be paid to the choice of antibiotics.

• Pediatric Infection and Vaccine
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• v.5 no.2
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• pp.239-244
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• 1998

Purpose : The incidence of hepatitis A virus infection in Korea has decreased recently. However, the prevalence in children and young adults is on an increasing trend in Inchon-Kyunggi prefecture. Economic development that leads to better living conditions and improves hygiene facilities has reduced the rate of HAV infection. This study was designed to evaluate the recent seroprevalence rate of hepatitis A in children and adolescents. Methods : Study population consisted of 612 children and adolescents aged 1 to 17 years in Inchon-Kyunggi prefecture. Serum samples were collected between 1996 and 1997 and tested for anti HAV by Microparticle Enzyme Immunoassay(MEIA). Results : According to age, the seropositive rates were 10.5%(male 13%, female 6.7%) in 1 year-old group, 0% in 3, 5, 11 and 13 year-old group, 6%(male 8%, female 4%) in 15 year-old group, and 11%(male 14%, female 8%) in 17 year-old group. Conclusion : This study showed that seropositive rate of HAV infection increased with age. While it revealed extremely low incidence of HAV infection in children less than 13 years old, they are also likely 10 be exposed 10 the infection. Our findings suggest that the effective administration of vaccination is needed in selected and high risk groups.