• Title/Summary/Keyword: 점진적 추출

Search Result 168, Processing Time 0.023 seconds

Effect of Ecklonia stolonifera Extracts on Bone Turnover Markers in Ovariectomized Rats (곰피가 갱년기 장애 유도 흰쥐의 골 대사 지표물질의 변화에 미치는 영향)

  • Kim, Young-Kyoung;Kim, Mi-Hyang
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.39 no.12
    • /
    • pp.1769-1775
    • /
    • 2010
  • Menopause is often associated with the incidence of several chronic diseases including osteoporosis, cardiovascular disease, and obesity. The purpose of this study was designed to evaluate the possibility of osteoporosis prevention in postmenopausal women. In this study, we investigated the effects of Ecklonia stolonifera (ES) extracts on bone turnover markers in ovariectomized rats. For this study, the following four groups of 9-week-old Sprague-Dawley rats were evaluated over 6 weeks: normal rats (SHAM), ovariectomized rats (OVX-CON) and ovariectomized rats that were treated with ES extracts. We measured the osteocalcin and C-telopeptide of collagen cross-links (CTx) content, enzyme ALP activity in serum and collagen content in the cartilage, bone, skin and lungs. We found that the levels of indicators of bone metabolism such as alkaline phosphatase (ALP), osteocalcin and CTx were lower in rats in the ES extract group than the OVX-CON group. In addition, the collagen contents in the bone, cartilage, skin and lungs decreased in response to ovariectomy, but the levels of collagen were greater in the bone of rats that were treated with ES extract than in the bone of rats in the OVX-CON group. These results suggest that the ES may be an effective functional food to prevent osteoporosis in postmenopausal women.

Biological and Physicochemical Properties of Porcine Epidemic Diarrhea Virus Chinju99 Strain Isolated in Korea (국내 분리 돼지 유행성설사 바이러스 Chinju99주의 생물학적 및 물리화학적 성상)

  • Lee, Hee-Kyung;Yeo, Sang-Geon
    • Journal of Veterinary Clinics
    • /
    • v.20 no.2
    • /
    • pp.150-154
    • /
    • 2003
  • A disease with severe diarrhea occurred in a herd of one thousand, 1-week-old piglets in Chinju, Korea, and was diagnosed as porcine epidemic diarrhea by the detection of N gene of porcine epidemic diarrhea virus (PEDV) from small intestines. A PEDV, named as Chinju99, was also isolated from the intestines after two blind-passages in Vero cells supplemented with trypsin (10 ug/ml). and the biological and physicochemical properties of the isolate were characterized. The virion was roughly spherical in shape and had spike peplomers on its outer surface. The virus exhibited cytopathic effects such as rounding degeneration at initiation of infection and syncytia formation later in Vero cells. The virus was labile to 20% ether and 5% chloroform but stable in acid with pH 4-7 at $4^{\circ}C$. The infectivity of the virus was maintained at $50^{\circ}C$ for 180 min, and the buoyant density of the virus in sucrose was 1.180 g/ml. All biological and physicochemical properties of the virus were typical features of coronaviruses.

Traffic Attributes Correlation Mechanism based on Self-Organizing Maps for Real-Time Intrusion Detection (실시간 침입탐지를 위한 자기 조직화 지도(SOM)기반 트래픽 속성 상관관계 메커니즘)

  • Hwang, Kyoung-Ae;Oh, Ha-Young;Lim, Ji-Young;Chae, Ki-Joon;Nah, Jung-Chan
    • The KIPS Transactions:PartC
    • /
    • v.12C no.5 s.101
    • /
    • pp.649-658
    • /
    • 2005
  • Since the Network based attack Is extensive in the real state of damage, It is very important to detect intrusion quickly at the beginning. But the intrusion detection using supervised learning needs either the preprocessing enormous data or the manager's analysis. Also it has two difficulties to detect abnormal traffic that the manager's analysis might be incorrect and would miss the real time detection. In this paper, we propose a traffic attributes correlation analysis mechanism based on self-organizing maps(SOM) for the real-time intrusion detection. The proposed mechanism has three steps. First, with unsupervised learning build a map cluster composed of similar traffic. Second, label each map cluster to divide the map into normal traffic and abnormal traffic. In this step there is a rule which is created through the correlation analysis with SOM. At last, the mechanism would the process real-time detecting and updating gradually. During a lot of experiments the proposed mechanism has good performance in real-time intrusion to combine of unsupervised learning and supervised learning than that of supervised learning.

Expression of Id-1 Gene in Mouse Uterus (생쥐 자궁에서의 Id-1 유전자의 발현)

  • Nah, Hee-Young;Hong, Seok-Ho;Lee, Ji-Yoon;Chae, Hee-Dong;Kang, Byung-Moon;Kim, Chung-Hoon
    • Clinical and Experimental Reproductive Medicine
    • /
    • v.30 no.2
    • /
    • pp.171-178
    • /
    • 2003
  • 연구 목적: Microarray data에 의해 밝혀진 생쥐자궁에서의 Id 유전자의 hormonal effect와 implantation process 동안의 관계를 조사하고자 실험을 수행하였다. 연구재료 및 방법: 난소절제한 생쥐에 estrogen을 주사하고 6시간, 12시간이 지난 후 자궁을 적출하여 두 가지 방법으로 sample을 준비하였다. 먼저 자궁전체의 RNA를 추출하여 실험하거나 laser capture microdissection (LCM) 방법으로 자궁내막상피세포, 자궁기질세포, 자궁근육층으로 분리하여 RNA를 추출하고 semi-quantative RT-PCR을 수행하여 Id 유전자의 발현을 조사하였다. 임신 4.5일째 생쥐에 Chicago blue dye를 주사하여 착상부위와 비착상부위를 분리하고 RNA를 추출하여 Id 유전자의 발현을 semiquantitative RT-PCR 방법으로 실험하였다. 결 과: Estrogen을 처리한 난소절제된 생쥐 자궁에서의 cDNA microarray 자료에서 Id-1 mRNA는 점진적으로 두 배 이상 증가하였고 Id-2 mNRA는 반대로 시간이 지날수록 두 배 이상 감소하였다. Microarray 자료를 재확인하기 위해 semi-quantitative RT-PCR을 이용하여 실험하였고, 그 결과 Id-1 유전자는 estrogen 처리 6시간까지는 큰 변화가 없었으나 12시간에서는 4배 이상의 높은 발현을 보였으며, Id-2 mRNA의 발현은 estrogen 처리 6시간과 12시간 모두에서 대조군에 비해 4배 가량 감소하였다. 이 실험군을 LCM을 이용하여 자궁내막상피세포, 자궁기질세포, 자궁근육층을 각각 분리하여 실험한 결과 estrogen 처리군에서 Id-1의 발현은 자궁내막상피세포에서만 높은 발현을 보였으며, estrogen 처리 6시간과 12시간에는 큰 차이를 보이지 않았다. 그러나, Id-2 mRNA는 자궁내막상피세포에서 estrogen 처리 6, 12시간 모두에서 높은 발현을 보였고, 근육세포층에서는 estrogen 처리 6시간에서는 변화가 거의 없었으나 12시간에는 현저하게 증가하였다. 단, 자궁기질세포에서는 대조군에 비해 estrogen 6, 12시간에서 Id-2 mRNA의 발현이 감소하였다. 임신한 생쥐 자궁의 착상부위에서는 Id-1 mNRA의 발현은 비착상부 위보다 월등하게 높은 증가를 보였다. 결 론: 난소절제 생쥐를 이용한 실험에서 Id-1, -3는 estrogen에 의해 발현이 증가하고, Id-2는 발현이 감소하였다. LCM을 이용한 실험에서는 Id-2는 이와는 달리 부위별 발현양상은 다르게 나타났지만 이는 넓은 부위를 차지하는 자궁기질에서의 발현감소가 전체적인 Id-2의 발현양상으로 나타난 것으로 추측된다. 착상부위에서의 Id의 발현은 Id-1만이 유일하게 월등한 증가를 보였다. 위의 결과를 종합해 볼 때 생쥐 자궁에서 Id 유전자는 estrogen에 의해 조절되며 직, 간접적으로 착상시기에 다양한 작용을 할 것으로 사료된다.

Iso-density Surface Reconstruction using Hierarchical Shrink-Wrapping Algorithm (계층적 Shrink-Wrapping 알고리즘을 이용한 등밀도면의 재구성)

  • Choi, Young-Kyu;Park, Eun-Jin
    • Journal of KIISE:Computer Systems and Theory
    • /
    • v.36 no.6
    • /
    • pp.511-520
    • /
    • 2009
  • In this paper, we present a new iso-density surface reconstruction scheme based on a hierarchy on the input volume data and the output mesh data. From the input volume data, we construct a hierarchy of volumes, called a volume pyramid, based on a 3D dilation filter. After constructing the volume pyramid, we extract a coarse base mesh from the coarsest resolution of the pyramid with the Cell-boundary representation scheme. We iteratively fit this mesh to the iso-points extracted from the volume data under O(3)-adjacency constraint. For the surface fitting, the shrinking process and the smoothing process are adopted as in the SWIS (Shrink-wrapped isosurface) algorithm[6], and we subdivide the mesh to be able to reconstruct fine detail of the isosurface. The advantage of our method is that it generates a mesh which can be utilized by several multiresolution algorithms such as compression and progressive transmission.

A Study of How to Improve Execution Speed of Grabcut Using GPGPU (GPGPU를 이용한 Grabcut의 수행 속도 개선 방법에 관한 연구)

  • Kim, Ji-Hoon;Park, Young-Soo;Lee, Sang-Hun
    • Journal of Digital Convergence
    • /
    • v.12 no.11
    • /
    • pp.379-386
    • /
    • 2014
  • In this paper, the processing speed of Grabcut algorithm in order to efficiently improve the GPU (Graphics Processing Unit) for processing the data from the method. Grabcut algorithm has excellent performance object detection algorithm. Grabcut existing algorithms to split the foreground area and the background area, and then background and foreground K-cluster is assigned a cluster. And assigned to gradually improve the results, until the process is repeated. But Drawback of Grabcut algorithm is the time consumption caused by the repetition of clustering. Thus GPGPU (General-Purpose computing on Graphics Processing Unit) using the repeated operations in parallel by processing Grabcut algorithm to effectively improve the processing speed of the method. We proposed method of execution time of the algorithm reduced the average of about 95.58%.

Weed Control Efficacy of the Residues and its Aqueous Extract of Sorghum Shoots (수수 지상부의 부산물과 추출물의 제초활성)

  • Park, Su Hyuk;Won, Ok Jae;Le, Thi Hien;Eom, Min Yong;Hwang, Ki Seon;Hwang, Jae-Bok;Park, Kee Woong
    • Weed & Turfgrass Science
    • /
    • v.4 no.3
    • /
    • pp.243-248
    • /
    • 2015
  • This study was conducted to investigate the ability for weed control of the shoot extract of sorghum (Sorghum bicolor (L.) Moench) and developing a sustainable weed management in organic farming. When the dried shoot powder was mixed with soil and treated with 2 cm above the soil surface, the germination for Echinochloa crus-galli, Digitaria cilialis, Abutilon theophrasti and Amaranthus retroflexus was inhibited maxium 40%. The growth inhibition of germinated seedlings in the A. theophrasti and A. retroflexus was maxium 30% while it was less than 30% in the E. crus-galli and D. cilialis. Shoot extracts at rates above $25mg\;ml^{-1}$ was effective to inhibit germination of D. cilialis, A. theophrasti and A. retroflexus. The shoot extract concentration required for 50% of germination inhibition was $60mg\;ml^{-1}$ in the E. crus-galli, while it was less than $10mg\;ml^{-1}$ in the D. cilialis, A. theophrasti and A. retroflexus. For the foliar application, 11 adjuvants were tested at 0.5% and DOS70, TM15 and TDE7 were most effective adjuvants for the shoot extracts. DOS70 was most effective and provided up to 60% of weed control efficacy for the tested four weed species. Though herbicidal efficacy of sorghum shoot was not enough to give a proper weed control, it can be expected that long term use of sorghum shoots can provide gradual decrease in weed seeds and weed density.

Detecting Dissolve Cut for Multidimensional Analysis in an MPEG compressed domain : Using DCT-R of I, P Frames (MPEG의 다차원 분석을 통한 디졸브 구간 검출 : I, P프레임의 DCT-R값을 이용)

  • Heo, Jung;Park, Sang-Sung;Jang, Dong-Sik
    • Journal of the Institute of Convergence Signal Processing
    • /
    • v.4 no.3
    • /
    • pp.34-40
    • /
    • 2003
  • The paper presents a method to detect dissolve shots of video scene change detections in an MPEG compressed domain. The proposed algorithm uses color-R DCT coefficients of Ⅰ, P-frames for a fast operation and accurate detection and a minimum decoding process in MPEG sequences. The paper presents a method to detect dissolve shot for three-dimensional visualization and analysis of Image in order to recognize easily in computer as a human detects accurately shots of scene change. First, Color-R DCT coefficients for 8*8 units are obtained and the features are summed in a row. Second, Four-step analysis are Performed for differences of the sum in the frame sequences. The experimental results showed that the algorithm has better detection performance, such as precision and recall rate, than the existing method using an average for all DC image by performing four step analysis. The algorithm has the advantage of speed, simplicity and accuracy. In addition. it requires less amount of storage.

  • PDF

An Analysis of the Coastal Topography and Land Cover Changes in the Haeundae Beach (해운대 해수욕장의 해안지형 및 토지피복 변화 분석)

  • Yang, Ji-Yeon;Choi, Chul-Uong
    • Journal of the Korean Association of Geographic Information Studies
    • /
    • v.9 no.1
    • /
    • pp.101-115
    • /
    • 2006
  • As coastal erosion is increasing sharply because of sudden changes in the natural environment and increases in artificial development, the problem of coastal erosion become an important issue, socially and economically. To building the data which needed to grasp the situation and find a solution, we need the monitoring system for long-term. In this study, we analyzed the coastal topography and land cover changes in the Haeundae Beach during 60 years. The Haeundae Beach is the most famous beach in the country and coastal erosion are going on. First, we analyzed the change of coastal topography by calculated the coastline and area of the beach using aerial photos during 60 years. We extracted the coastline by digitized on aerial photo and corrected the height of tide level using sounding and GPS survey data. And we computed the area of beach and analyzed the change of area during 60 years. Second, we analyzed the change of land cover using landcover map. We made the detailed landcover map by on-screen digitizing and estimated the soil loss for the area nearby Haeundae Beach. As a result, we could see that the coastline get nearer to land and the area of beach has been reduced in general. We think that interception of sand supply by the development is the artificial cause of coastal erosion. The result of this study would be useful in long-term coastal monitoring and to analyze the cause of coastal environment change. We expect that the result is available on the coastal information system.

  • PDF

Quality Characteristics of Fermented Perilla Leaves Ice Cream Using Probiotics (프로바이오틱스를 이용한 발효 깻잎 아이스크림의 품질특성)

  • SangSun Hur
    • Journal of the Korean Applied Science and Technology
    • /
    • v.41 no.2
    • /
    • pp.375-385
    • /
    • 2024
  • The purpose of this study is to manufacture ice cream with perilla leaves fermented extract(5%, 10%, 15%, and 20% w/v) fermented by Lactobacillus acidophilus KCTC 3164 strain as functional additives. The physical and chemical properties(color, viscosity, pH, total acidity, melting rate, overrun) and antioxidant activity of ice cream with perilla leaves fermented extract were evaluated. The addition of perilla leaves fermented extract affected the color of the ice cream, and the melting rate increased with increasing addition of perilla leaves fermented extract. In contrast, viscosity showed a gradual decrease. Overrun increased gradually with higher levels of perilla leaves fermented extract, while pH decreased significantly, and total acidity increased. The DPPH radical scavenging activity and total polyphenol content of ice cream with perilla leaves fermented extract significantly increased with higher concentrations of fermented perilla leaves extract. The results of this study indicate that the ice cream sample with 10% fermented perilla leaves extract has a potential as a functional ice cream since it exhibited high overrun, a low melting rate, the desired viscosity, and high DPPH radical scavenging activity and total polyphenol content.