• Title/Summary/Keyword: 젊은 성인

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Two Cases of Pulmonary Eosinophilic Granuloma (폐 호산구성 육아종 2예)

  • Choi, Wan-Young;Yoo, Yong-Keol;Park, Dong-Il;Shin, Dong-Ho;Park, Sung-Soo;Lee, Jung-Hee;Jeon, Seok-Chul;Chung, Won-Sang;Park, Chan-Pil;Park, Moon-Hyang;Lee, Jung-Dal
    • Tuberculosis and Respiratory Diseases
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    • v.39 no.2
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    • pp.186-193
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    • 1992
  • Eosinophilic granuloma (histiocytosis $\times$) is an uncommon granulomatous disorder affecting the mononuclear phagocytic cell system caused by unknown etiology. When confined to the lungs, it is also known as pulmonary eosinophilic granuloma or pulmonary histiocytosis $\times$. After the first case was described in 1951 by Farinacci et ai, more 250 cases were reported in the English literature. However only 4 cases has been introduced in our country. We describe two additional cases. In both cases, open lung biopsies are performed for definite diagnosis and examined by immunohistochemical stain for S-100 protein and electron microscopy for ultrastructural identification of Birbeck granule.

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Kimura's Disease of the Distal Arm - A Case Report - (상완 원위부에 발생한 기무라씨 병 - 증례 보고 -)

  • Yoon, Jong-Pil;Jo, Ki-Hyun;Min, Hak-Jin;Yoon, Ui-Seoung;Seo, Jae-Seong;Kim, Jin-Soo;Baak, Cheol-Hee
    • Clinics in Shoulder and Elbow
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    • v.11 no.2
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    • pp.196-200
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    • 2008
  • Kimura's Disease is a very rare, chronic inflammatory disorder with an unknown etiology, and this illness is primarily seen in young Asian males. The typical clinical features consist of painless subcutaneous masses in the head or neck region, and especially in the salivary gland and submandibular region. It is often accompanied with a regional lymphadenopathy, peripheral blood eosinophilia and elevated serum IgE levels. Histologically, it is characterized by prominent germinal centers in the involved lymph nodes, together with eosinophilic infiltration in these lymph nodes. The treatment modalities for this disease are steroid therapy, radiation therapy and surgical excision. Its clinical course is of a benign nature. We report here on a case of a 28 year old man who had a soft tissue mass in his left arm. We excised this mass and the microscopy confirmed that he suffered from Kimura's disease on microscopic examination in his left distal arm.

The Effects of Exercise-induced Fatigue on Knee Joint Position Sense in the Young, Elderly Adults and Stroke Patients (젊은 성인, 노인, 뇌졸중 환자들의 근 피로 유발이 무릎관절 위치 감각에 미치는 영향)

  • Kwon, Oh-Sung;Lee, Seung-Won;Seo, Dong-Kwon;Kim, Ji-Seon
    • Journal of the Korean Society of Physical Medicine
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    • v.8 no.4
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    • pp.619-625
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    • 2013
  • PURPOSE: The purpose of this study was to determine the effects of muscle fatigue on knee joint position sense in the young, elderly adults, and stroke patients. METHODS: The subjects were recruited into three groups; young group(YG)(N=15), elderly group(EG)(N=15), and stroke group(SG)(N=15). Exercise-induced fatigue was achieved by repeated active exercise 60 times on an angle at 10 to 100 degrees of the knee joint with an angle speed of $120^{\circ}/s$, with three sets for 15 minutes. Evaluation was performed for determination of repositioning error using passive angle repositioning (PAR) and active angle repositioning (AAR). RESULT: Regarding the error score for the knee joint position sense in both the baseline and muscle fatigue, significant increases were observed between the YG and EG (p<.05), and between the EG and SG (p<.01), and between YG and SG (p<.05) in the PAR, YG and SG (p<.05) in the AAR. CONCLUSION: In particular, the results of this study indicate that management and intervention for elderly adults and stroke patients can result in improvement of proprioception.

Tendon Transfer for Irreparable Massive Rotator Cuff Tear (봉합이 불가능한 회전근 개 광범위 파열에 대한 건 이전 수술)

  • Yum, Jae-K.;Lee, Hee-Sung;Park, Sung-Bum
    • Clinics in Shoulder and Elbow
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    • v.13 no.1
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    • pp.161-166
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    • 2010
  • Purpose: Irreparable massive rotator cuff tears pose a distinct clinical challenge for the orthopaedist and non-surgical treatment has had inconsistent results and proven unsuccessful for chronic symptoms, while surgery, including debridement and partial and complete repairs have had varying degrees of success. Materials and Methods: For rotator cuff tears that are deemed irreparable, treatment options are limited. Results and Conclusion: The use of tendon transfers (latissimus dorsi for posterosuperior type cuff defects and pectoralis major for subscapularis defects) in younger patients to reconstruct rotator cuffs and re-establish function and restore shoulder kinematics can be useful in solving this difficult problem.

Predicting User Acceptance of Strong AI using Extension of Theory of Planned Behavior: Focused on the Age Group of 20s (확장된 계획적 행동이론을 통해 본 강한 인공지능 제품에 대한 이용자의 수용의도: 20대 연령층을 중심으로)

  • Rhee, Chang Seop;Rhee, Hyunjung
    • The Journal of the Korea Contents Association
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    • v.20 no.10
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    • pp.284-293
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    • 2020
  • The rapid progress of AI technology gives us the expectation to solutions to various problems in our society, and at the same time, it gives us anxiety about the side effects that can occur if AI develops beyond human control. This study was conducted in the early 20s with less objection to advanced devices. We attempted to provide clues to understand thoughts and attitudes of the targets about the future environment that will be brought by AI through the process of finding intent the acceptance of strong AI technology. For this, we applied the Theory of Planned Behavior, and further expanded this research model to identify factors affecting the attitude toward AI. As a result, the attitude toward AI and perceived behavioral control had a significant effect on the intention to use to strong AI. In addition, we found that the expectation of the benefit of improving task performance and the anxiety on the threat of relationship disturbance had a significant effect on the attitude toward AI. This study suggests implications for AI-related companies establishing the direction of technology development and for government setting a policy direction for AI adoption.

A case of hereditary pancreatitis with a N29I mutation in the cationic trypsinogen gene (Cationic Trypsinogen N29I 유전자 변이에 의한 유전 췌장염 1례)

  • Shin, Jee Youn;Oh, Dae Sung;Rheu, Jeong Min;Shim, Jeong Ok;Park, Ji Sook;Ko, Jae Sung;Seo, Jeong Kee
    • Clinical and Experimental Pediatrics
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    • v.49 no.10
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    • pp.1111-1115
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    • 2006
  • Hereditary pancreatitis is an autosomal dominant disease characterized by recurrent episodes of pancreatitis, often beginning in childhood, with a positive family history involving at least two other affected family members with no known other precipitating factors. Most forms of hereditary pancreatitis are caused by one of two common mutations, i.e., R122H in exon 3 and N29I in exon 2 of the cationic trypsinogen (CT) (PRSS1) gene, located on chromosome 7. The authors describe the case of a 15-year-old boy who had suffered from recurrent attacks of pancreatitis since age three. His mother and grandmother had chronic pancreatitis and diabetes mellitus. Mutation analysis was performed on the family due to the suspicion of hereditary pancreatitis. The CT gene was analyzed in DNA samples extracted from the peripheral blood of three family members, the mother, the proband, and the proband's sister. Two members of the family, the mother and the proband, were found to have a N29I mutation in the CT gene. The authors document the first family with hereditary pancreatitis associated with the N29I mutation in Korea.

How to Make R&D Proposal? (연구계획서 작성법)

  • Min, Tae-Seon
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2011.05a
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    • pp.13-13
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    • 2011
  • 1. 연구계획서 작성시 필수적으로 기술하여야 할 항목 - 연구의 중요성 - 깊이가 있는 명확한 가정 - 연구목표의 달성 개연성: 양질의 선행연구 결과 및 그림 데이터 - 논리적 전개 및 실험 설계: 가정을 뒷받침할 만한 실험결과 - 주어진 기간 내에 제안한 것들을 달성할 수 있는지 여부 : 지나친 욕심이 젊은 과학자가 나쁜 평가를 받을 수 있는 가장 일반적인 실수 2. 연구계획서를 작성하기 전에.. - 정말 연구계획서를 제출할 적기인가? 너무 이른 것이 아닌지? - 타인에 의해 이미 실험된 것이 아닌지? - 충분한 시간을 두고 작성 ? 최소 2~3개월 전 연구계획서를 미리 작성한 후 동료 또는 선배에게 초안을 보여주고 검토를 받는 것이 매우 중요함: 제출하기 전에 혹독한 비판을 감수 3. 연구목표 - 흥미롭고 중요한 문제(issue)를 적절히 강조하고 있는지? - 가정에 근거하고 있는지? - 목표가 win-win 인지?: 즉, 연구성과가 현재 통용되고 있는 일반적인 가정들과 맥을 같이 하는지? 4. 연구배경 - 확실하고 체계적이어야 함 : 부제(subtitle) 사용. 주제의 중요성이 분명하게 시각적으로 드러나야 함. - 연구결과 파생될 기대효과를 현재와 비교하여 분명한 차이점을 기술 - 연구계획서에서 참고한 것들이 기존지식을 갱신한 것이고 최근 연구동향을 반영한 것이라는 것을 분명히 하여야 함. 5. 예비결과 - 과거 연구성과를 가능한한 많이 기술. ? 현재의 연구계획을 도출하게 된 근거를 과거의 연구와 연관시켜 강조하여야 함. ? 최소한 연구계획서에 기술된 연구방법의 개연성을 기술하여야 함. - 성과가 높지 않은 예비결과는 제시않는 것이 효율적임 - 연구계획서에 제시된 연구방법이 선험 연구에 근거한 것임을 강조하여야 함 ? 만일 전문성이나 선험연구결과가 없을 때는, 경험있고 영향력 있는 조언자나 공동연구자를 열거하고, 그들의 공동연구 동의서를 첨부하여야 함. ? 특히, 공동연구자들이 어떤 부분에서 협력할 것인지 구체적으로 기술하여야 함. - 필요한 부분에서 적절하게 구체적 수치와 raw data를 제시

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Effect of Walking Speed on Lower Extremity Internal and External Rotation While Turning 90 Degrees (90도 회전 시 보행속도가 하지의 내외 회전에 미치는 효과)

  • Yoon, Jang-Whon
    • Physical Therapy Korea
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    • v.8 no.4
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    • pp.1-16
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    • 2001
  • 회전(turning)은 보행 중 방향을 바꾸는 운동 기술(motor skill)이고, 회전 전략(turning strategy)은 회전을 완수하는데 사용되는 일반적 행동 전형(generalized movement pattern)이다. 회전에 대한 보행속도의 영향은 분명하지 않다. 이 연구의 목적은 보행속도의 돌기 전략에 대한 영향을 분석하고 보행속도의 하지 내외 회전(internal and external rotation)에 대한 영향을 분석하는 것이다. 건강한 젊은 성인 15명이 이 연구에 자발적으로 참여하였다. 맥리플렉스 측정 장치(MacReflex measurement system)가 동작 분석(motion analysis)을 위해 사용되었다. 각각의 자원자들은 보행 중 90도 왼쪽으로 회전을 10회씩 완수하였다. 각각의 시도마다 보행속도를 다르게 하기 위해서 세 가지의 다른 요구들(slow, regular, fast)이 임의적으로 주어졌고 각각의 실제 보행속도가 자원자의 무게중심 변화에 따라 구해졌고 요구별 평균이 구해졌다. 회전 안쪽 발의 스핀(in side foot spin)은 보행속도가 증가함에 따라 증가했지만, 회전 바깥쪽 발의 스핀(out side foot spin)은 보행속도와 상관이 없었다. 하지의 내외 회전은 보행속도와는 상관이 없었지만, 같은쪽 발의 스핀과는 역관계가 있었다. 회전은 발 스핀이 있는 돌기와 발 스핀이 없는 돌기로 구분되는 것이 합당한 듯 하다. 제한된 시간과 공간 내에서 스핀은 보행속도가 빨라질수록 몸의 전방 운동량(forward momentum)에서 몸의 전방 운동량(forward momentum)으로의 전환이 스핀이 없는 회전 시보다 효율적이다. 고관절의 내외 회전 근육들은 회전전략에 상관없이 회전되는 동안 몸의 역학(body mechanics)을 조절하는데 중요한 역할을 맡고 있는 것으로 보인다. 앞으로 회전 시 몸의 생체 역학적 그리고 신경 근육적 기전들(biomechanical and neuromuscular mechanisms)을 밝히는 연구들이 필요하다.

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Effect of 8 weekas aerobic dance training on the body composition, cardiopulmonary function and blood cholesterol concentration in young women (젊은여성에서 8주간의 aerobic dance 훈련이 체구성, 심폐기능, 혈중 콜레스테롤 농도에 미치는 효과)

  • 최명애
    • Journal of Korean Academy of Nursing
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    • v.18 no.2
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    • pp.105-117
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    • 1988
  • To evaluate training effect, aerobic dance was performed by eight female collegestudents for 8 weeks. Body composition, cardiopulmonary function at rest and during maximal exercise, blood cholesterol concentration at rest were determined before and after 8weeks of aerobic dance training. Maximal exercise was performed on the treadmill according of Bruce protocol. Pre to post training differences were evaluated. The results obtained were as follows : 1. After the training, skinfold thickness and total body fat decreased significantly(p<0.1) while lean body mass increased with significance (p<0.1). 2. Heart rate and arterial blood pressure at rest decreased without sinificance after the training. 3. As a result of training, forced vital capacity and forced expiratory volume for a second increased significantly (p<0.01, p<0.1). 4. After the training period, heart rate at 3, 6, and 9 min. during treadmill exercise was significantly lower than those of pretraining (p<0.05). 5. After the training, systolic and diastolic blood pressure at 6 and 9 min during the exercise was significantly lower than those of pretraining (p<0.025, p<0.1). 6. After the training, oxygen uptake at 3 and 6 min during the exercise was significantly greater than those of pretraining (p<0.05). 7. As a result of training, the maximal oxygen uptake increased significantly during the exercise (p<0.1). 8. After the training, expired air volume for a minute at 3 and 6 min during the exercise was signigicantly grerter than those of pretraining (p<0.1). 9. After the training, repiratory quotient during the exercise was lower than pretaining without significance. 10. After the training, blood HDL -cholesterol concentration incereased with significance, (p<0.1) blood total cholesterol and triglycerids concentration decreasedsignificantly (p<0.1). From these results, it may be concluded that 8 week aerobic dance training reduces skinfold thickness and body fat contents, improves the cardiopulmonary function and tissue oxygen utilization, reduces blood cholesterol and triglyceride concentration and brings about the increase of blood HDL-cholesterol concentriation.

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Two cases of central nervous system complications caused by Mycoplasma pneumoniae infection (Mycoplasma pnuemonia 감염에 의한 중추신경계 합병증 2례)

  • Kim, Shin Mi;Heo, Ji Seung;Shim, Eun Jung;Lee, Dae Hyoung;Cho, Do Jun;Kim, Dug Ha;Min, Ki Sik;Yoo, Ki Yang
    • Clinical and Experimental Pediatrics
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    • v.51 no.5
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    • pp.533-537
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    • 2008
  • Mycoplasma pneumoniae (M. pneumoniae) infection causes a wide variety of clinical manifestations in children and young adults, the main one being pneumonia. M. pneumoniae is transmitted from person to person by infected respiratory droplets. Symptoms caused by M. pneumoniae infection can be divided into those involving the respiratory tract, and those caused by extrapulmonary disease. M. pneumoniae infections may cause central nervous system (CNS) complications-with encephalitis being the most frequent-and stroke being a rare complication. The pathogenesis of the CNS disease is unclear; possibilities include direct infection and an immune-mediated reaction. We present two cases of CNS complications subsequent to infection with M. pneumoniae; both cases had convincing evidence of preceding M. pneumoniae respiratory disease with no evidence of viable M. pneumoniae in the cerebrospinal fluid. We report cases of encephalitis and stroke following a recent M. pneumoniae infection.