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Ductal carcinoma in situ arising within a fibroadenoma of breast (유방의 섬유선종에서 발생한 관상피내암)

  • Won, Tae Wan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.11
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    • pp.454-458
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    • 2017
  • Fibroadenoma are one of the most common benign tumors of the breast in young women. Fibroadenoma may be associated with fibrocystic change, proliferative epithelial changes, and extremely rarely with carcinoma. We report here two cases of malignancy arising from a breast fibroadenoma. The patients were 19 and 51 years old and presented with a lump of recent onset. A 19-year-old female patient was diagnosed with mass excision at another hospital, and re-excision was performed at the hospital. Ultrasonography and cytologic examination revealed fibroadenoma and malignancy in a 51-year-old female patient, who was treated with wide excision. The pathological report of the two cases was revealed as DCIS in a fibroadenoma. Because carcinoma arising within a fibroadenoma is so rare, there are few reports of its characteristics or guidelines for treatment. Careful analysis of the unusual carcinoma arising within a fibroadenoma of the breast led to appropriate diagnosis and treatment of various types of lesions. Herein, we report two cases of DCIS arising within a fibroadenoma of the breast and provide a review of the literature.

Endobronchial Metastasis from Renal Cell Carcinoma -A case report- (신장세포암의 기관지내 전이 - 1예 보고 -)

  • Kim, Si-Wook;Shin, Yoon-Mi
    • Journal of Chest Surgery
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    • v.41 no.3
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    • pp.386-389
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    • 2008
  • Lung parenchyma is a common organ for metastases of extrathoracic tumors, but endobronchial metastasis is very rare. In this report, we present a case of endobronchial metastases from renal cell carcinoma (RCC), and this was managed by performing operative resection. A 63-year-old man presented with frequent dry cough; he had previously undergone left nephrectomy and postoperative chemotherapy for grade 2 RCC eight years ago. Computed tomography and bronchoscopy showed an endobronchial tumor from the left lower lobe bronchus to the second carina, and this mass was diagnosed as a necrotic tissue with chronic inflammation at biopsy. During the operation, the mass was revealed to be a metastatic renal cell carcinoma on the frozen section diagnosis and there was no mucosal invasion on the resection margin of the left lower lobe bronchus. We performed lobectomy of the left lower lobe with systemic dissection of the mediastinal lymph nodes. The final histopathologic diagnosis of the endobrochial mass was metastatic RCC and any mediastinal lymph node metastasis was not found. The patient was discharged on postoperative day 10 without any postoperative complications.

HUGE PLEOMORPHIC ADENOMA OF THE PAROTID GLAND: REPORT OF A CASE (이하선에 발생한 거대 다형성 선종)

  • Ryu, Sun-Youl;Ryu, Seung-Hee;Kim, Tae-Hee
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.28 no.3
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    • pp.247-253
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    • 2006
  • Pleomorphic adenoma of the parotid gland typically presents as painless, mobile mass of long duration, and originate in the superficial lobe but, more rarely these tumors may involve the deep lobe of the parotid gland. The average size of a parotid neoplasm is 2 to 4 cm. The effective treatment of parotid pleomorphic adenoma is surgical excision. The simple excision or enucleation resulted in recurrence rate of 45% in benign tumor. Therefore, the superficial parotidectomy with identification and preservation of the facial nerve is now the most widely accepted surgery. We report a case of the huge pleomorphic adenoma of the left parotid gland in a 67-year-old man who complained the large mass, measured about $10\times7\times5$cm-sized, in front of the left ear and on the mandibular ascending ramus. The diagnosis was confirmed by the clinical examination, computed tomographic scan, fine needle aspiration, and incisional biopsy. Superficial parotidectomy including the tumor and preservation of the facial nerve using the modified Blair approach was performed. And satisfactory results have been obtained cosmetically and functionally.

A Case of Papillary Thyroid Cancer Presenting as Pleural Effusion (흉수로 발현한 유두모양 갑상샘암)

  • Jung, Ki Hwan;Seo, Ji A;Lee, Ju-Han;Jo, Won Min;Kim, Je Hyeong;Shin, Chol
    • Tuberculosis and Respiratory Diseases
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    • v.64 no.4
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    • pp.314-317
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    • 2008
  • We report the patient presented with a left-sided pleural effusion. Pleural fluid analysis revealed lymphocyte-dominant exudates with lower level of adenosine deaminase and negative cytologic malignancy. Thoracoscopic examination and histologic examination revealed metastatic nodules on pleurae, proven to be from the papillary thyroid cancer. There were no other sites of distant metastases. Though papillary thyroid cancer is characterized with slow progression and relatively good prognosis, metastatic pleural effusion as an initial manifestation of undiagnosed papillary thyroid cancer can be considered.

Pilomatricoma of the Shoulder Easily Identified by Color Doppler Ultrasound: A Case Report and Review of Literature (컬러 도플러 초음파를 이용하여 발견한 견부 모기질세포종: 증례보고)

  • Seo, Jun-Yeong;Kim, Tae Jung;Kim, Sang Rim;Nam, Kwang Woo
    • The Journal of Korean Orthopaedic Ultrasound Society
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    • v.6 no.1
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    • pp.10-14
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    • 2013
  • Pilomatricoma is a benign skin tumor that develops from hair matrix cells. It most commonly occurs in the head and neck, followed by the upper extremities. Accuracy of preoperative diagnosis was low in previous studies and excisional biopsy was even performed frequently without imaging studies. We report a case of pilomatricoma of the shoulder that was easily diagnosed by ultrasound including color Doppler, which is a more useful imaging modality than computed tomography or magnetic resonance imaging scans not only because of its cost effectiveness but also because of the precise information obtained from mass contents.

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Primary Pul monary Carcinosarcorna -A case of report- (폐의 원발성 암육종 -1례 보고-)

  • 안상구;김재영
    • Journal of Chest Surgery
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    • v.29 no.9
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    • pp.1036-1039
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    • 1996
  • Pulmonary carcinosarcon!as are rare malignant tumors consisting of an admixture of epithelial and mas- enchymal elements of the type ordinarily seen in malignancies of adults. Compared with all pulmonary neoplasms it occurs with a frequency of 0.3% and has a strong association with smoking. Carcinosarcomas be divided into two clinicopathologic groups based on the locution of the lung: a solid parenchymal type and a central or endobronchial lesion Noninvasive diagnostic tests have a rather low yield in detecting carcinosarcoma. The most frequent metastatic sites are hilar and mediastinal Lymph nodes. Surgical resection is both diagnostic and the initial treatment. The prognosis is poor and average postoperative survival is 9 months. We report one case of pulmonary carcinosarcoma demonstrated by immunohlstochemical staining in a 61 year old male patient with a review of literatures.

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Osteochondroma in Cervical Spine - 1 Case Report - (경추에서 발생한 골연골종 - 1예 보고 -)

  • Na, Hwa-Yeop;Lee, Young-Sang;Choi, Joon-Cheol;Choi, Jun-Won;Kim, Woo-Sung;Song, Woo-Suk;Noh, Hyoun-Min
    • The Journal of the Korean bone and joint tumor society
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    • v.14 no.1
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    • pp.73-77
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    • 2008
  • Osteochondroma is the most common benign tumor in bone, consist of 40%, but, rare in spine area occupying only 2%. We report a case of osteochondroma that was in the 5th and 6th spinous process of cervical spine. We performed en bloc excisional biopsy of the bony mass. And the patient is doing well without evidence of local recurrence at 1 year after surgery. Further follow-up is necessary to observe local recurrence.

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A Case of Endobronchial Aspergilloma Presented by Solitary Pulmonary Nodule (고립성 폐 결절 형태로 나타난 기관지 내 국균종 1예)

  • Lee Ki-Man;Kim Sung-Jin;Hong Jong-Myeon
    • Journal of Chest Surgery
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    • v.39 no.8 s.265
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    • pp.648-651
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    • 2006
  • A 53 year-old woman visited to our hospital due to increased hemoptysis for 4 days. The chest X-ray showed solitary pulmonary nodule on right upper lobe and computed tomography of chest demonstrated mass on posterior segmental bronchus of right upper lobe. Bronchoscopic examination revealed that this segmental bronchus was completely obstructed by a yellow and brownish mud like mass, which was identified as an aspergilloma by pathologic examination. Patient had undergone bilobectomy because of persistent hemoptysis. Tracheobronchial apergillosis in an immunocompetent person is very rare disease. then, we report this case with review of the Korean literature.

MULTIPLE MYELOMA OF MANDIBLE : REPORT OF A CASE (하악골에 발생한 다발성골수종의 증례보고)

  • Jang, Hyun-Seok;Lee, Gi-Cheol
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.18 no.4
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    • pp.706-711
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    • 1996
  • 다발성 골수증은 다양한 증세를 보이는 형질세포로부터 기원하는 악성종양으로 40세이상의 남성에서 호발되며 alkylating agent 단독, 혹은 corticosteroid와 병용하는 항암제 치료로 생존율이 크게 증가되기는 하였지만 치료후 평균생존기간의 20개월 내외로 완치율이 그다지 높지않은 형편이다. 악골에서의 발생은 극히 드물고 대개 늑골, 편평골, 척추, 골반, 두개골등에 광범위한 patchy destruction의 형태로 나타나는데 악골에 발생할 경우 임상증상은 장기적인 무통성 종창이 가장 흔하며 때로는 동통, 악골의 팽창, 감각이상, 치아의 동요, 악골골절등을 보이기도 한다. 전신적증상으로 무력감, 체중감소, 빈혈, 신부전, hypercalcemia, hyperiviscosity syndrome을 나타내기도 하는데 약 10%의 환자에서 전신적인 amyloidosis를 보인다. 진단은 골수생검상 골수의 plasmacytosis가 10% 이상이면서 혈장이나 뇨전기영동법에서 monoclonal globulin peak이 있을 때 가능하다. 여러 학자들은 처음에는 독립적인 고립성병소로 나타났다가 장기적으로 다발성골수종으로 이행됨을 주장하면서 장기적인 추적을 권하고 있지만 골내 고립성 형질세포종(solitary plasmacytoma in bone), 수질외 형질세포종(extramedullary plasmacytoma) 등은 다발성골수종과는 다른 질환이라 주장하는 등 아직 많은 논란이 있는 형편이다. 치료는 $4000{\sim}6000$ rad의 방사선치료와 여러 가지 약제의 복합적인 항암요법이 사용되고 있으며 국소적인 병소의 경우 외과적 절제술이 추천되기도 한다. 저자들은 59세 여자환자에서 하악골에 발생된 다발성골수종을 치험하였기에 문헌고찰과 함께 보고하는 바이다.

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Good's Syndrome (Thymoma with Immunodeficiency) -A case report- (Good 증후군 치험 -1예 보고-)

  • Ryoo, Ji-Yoon
    • Journal of Chest Surgery
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    • v.39 no.1 s.258
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    • pp.85-89
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    • 2006
  • Good's syndrome (thymoma with immunodeficiency) is a rare cause of combined B and T cell immunodeficiency in adults. The clinical characteristics are increased susceptibility to bacterial infection and opportunistic viral and fungal infections. The most consistent immunological abnormalities are hypogammaglobulinemia and reduced or absent B cells. This syndrome should be treated by resecting the thymoma and replacing the immunoglobulin to maintain adequate IgG values. The author experienced one case of Good's Syndrome. The patient was a 64-year-old female who had a history of frequent sinopulmonary infection. Chest CT showed Pneumonia and anterior mediastinal mass and PCNB was taken and biopsy result was thymoma. She received thymectomy and replacement of immunoglobulin to control hypogammaglobulinemia.