• The Korean Journal of Applied Statistics
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• v.20 no.3
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• pp.449-458
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• 2007

Bipolar disorder, also known as manic-depressive illness, is a brain disorder that causes unusual shifts in person's mood, energy, and ability to function. Compared with manic episode, the depression episode causes more serious results such as restless, loss of interest or pleasure, or thoughts of death or suicide and the cure rate of depression episode is lower than that of manic episode. Furthermore, a long term use of antidepressants in bipolar patients may result in manic episode. Our interest is to investigate the effect of antidepressant on switch of moods of bipolar patients and to estimate the transition probabilities of switch between moods, depression and (hypo) manic. In this study, three approaches are applied in terms of multi state model. Parametric model is applied using left censoring data and nonparametric model is implemented under illness-death model with counting process. In order to estimate the effect of covariates, a multiplicative model is used. These all methods have similar results.

• 재활복지
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• v.15 no.4
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• pp.27-47
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• 2011

The purpose of this research is to develop transition process and programmes for gently converting people with disabilities to local communities, through their empowerments. The methods used in the research were literature research, case studies on related programs, and expert interviews. The following shows the results. Firstly, the transition process for people with developmental disorders is exceedingly limited, and the process does not consider special attention needed for people with developmental disorders. Secondly, the postsecondary education programs for people with developmental disorders are being started as transition processes, however these programs need more connection with secondary schools. Thirdly, the primary factors which must be contemplated for University programs(for people with developmental disorders, after secondary education) are self-cognition and self-understanding. According to these results, we can suggest transition processes and programs within Universities for people with developmental disorders. (In Korea) Firstly, the postsecondary transition for people with developmental disorders requires a consideration of their characteristics, and mainstreaming education is also needed for their self-cognition and self-understanding. Considering this, the transition process within Universities can be an alternative. Secondly, tertiary educations within Universities for people with developmental disorders need to consider the following factors: ① The programs in Universities need to set up a support network. ② The door to program should be open to all students with developmental disorders within the Universities. ③ Organization of human resources must be systematized and connected, so that specialists within the Universities can participate in the postsecondary education programs for people with developmental disorders. ④ Inclusive learning activities must be under-taken, allowing students without disabilities to participate in the programs for students with developmental disorders.

• Korean Journal of Microbiology
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• v.44 no.1
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• pp.10-13
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• 2008

Endocrine disrupting chemicals (EDCs) are hard to be degraded in nature, and are also accumulated in diverse organisms. They finally give negative effects to human through the food web. White rot fungi which have lignin-degrading enzymes have high potentials for degradation of recalcitrant compounds, and a white rot fungus, Phlebia tremellosa, isolated in Korea show good degrading activity against the endocrine disrupting phthalates. We have isolated a laccase cDNA which was involved in the degradation of EDCs, and constructed a laccase expression vector to use in the genetic transformation of P. tremellosa. The expression vector was stably integrated into the chromosomal DNAs and showed increased laccase activity in transformants. One of transformants showed not only increased degradation of several EDCs but also faster estrogenic decreasing activities generated by the EDCs.

• Korean Journal of Psychosomatic Medicine
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• v.24 no.1
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• pp.28-42
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• 2016

Objectives : The author tried to find out reasons why and how hysteria(and conversion disorder) patient numbers, which were so prevalent even a few decades ago, have decreased and the phenotype of symptoms have changed. Methods : The number of visiting patients diagnosed with conversion disorder and their phenotype of symptoms were investigated through chart reviews in a psychiatric department of a University hospital for the last 12 years. Additionally, the characteristics of conversion disorder patients visiting the emergency room for last 2 years were also reviewed. Those results were compared with previous research results even if it seemed to be an indirect comparisons. The research relied on Briquet P. and Charcot JM's established factors of the vicissitudes of hysteria(and conversion disorder) which has been the framework for more than one hundred and fifty years since hysteria has been investigated. Results : The author found decreased numbers and changes of the phenotype of the hysteria patients(and conversion disorder) over the last several decades. The decreased numbers and changes of the symptoms of those seemed to be partly due to several issues. These issues include the development of the diagnostic techniques to identify organic causes of hysteria, repeated changes to the symptom descriptions and diagnostic classification, changes of the brain nervous functions in response to negative emotions, and the influence of human evolution. Conclusions : The author proposed that the evolutionary brain discord reaction theory explains the causes of disappearance of and changes to symptoms of hysteria(conversion disorder). Most patients with hysteria(conversion disorder) have been diagnosed in the neurological department. For providing more appropriate treatment and minimizing physical disabilities to those patients, psychiatrists should have a major role in cooperating not only with primary care physicians but with neurologists. The term 'hysteria' which had been used long ago should be revived and used as a term to describe diseases such as somatic symptom disorder, functional neurological symptoms, somatization, and somatoform disorders, all of which represent almost the same vague concept as hysteria.

• The Journal of the Convergence on Culture Technology
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• v.7 no.4
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• pp.95-104
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• 2021

This study was conducted for the purpose of convergence reconstruction of the transition education model for students with disabilities in Korea. Ultimately, this study was also conducted with the aim of enhancing the perspective of the development of a lifelong education support system for the disabled in connection with schools and communities. The research method consisted of a procedure with a meeting of experts based on the procedure of analyzing the previous research literature that tried to materialize the transition education model for students with disabilities from the viewpoint of connection between school age and adulthood. The contents of this study were reflected in the dimension of ensuring consistent connectivity validity based on the viewpoint of school-centered, community-centered, education, and welfare between special education and lifelong education for the disabled in order to reconstruct the conversion transition education model constructed in the current special education field. Accordingly, the transition education model for students with disabilities built in the field of special education centered on school age minimizes the tendency of a fragmented approach between school age and adulthood, and presents a standard basis and structure that can be linked to the entire adulthood. The transition education model was reconstructed convergence in terms of content.

• Proceedings of the Korean Information Science Society Conference
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• 2004.10c
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• pp.436-438
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• 2004

웹에서의 협업과 통합의 대표적인 기술이라 할 수 있는 웹 서비스의 사용은 날로 증가되고 있다 웹 서비스를 이용하여 애플리케이션을 구축할 때. 사용한 웹 서비스 중에서 장애가 발생했을 경우 애플리케이션의 신뢰성 있는 실행을 일해서는 장애를 극복할 수 있는 방법이 필요하다. 본 논문에서는 클라이언트측 애플리케이션에서의 수정 사항 없이 장애를 극복할 수 있는 시스템을 제안한다. 이 시스템에서는 일반적인 장애 상황뿐만 아니라 품질 요소들도 고려하여 요구사항에 만족하지 못할 경우 같은 서비스를 지원하는 웹 서비스로 자동 전환이 되도록 개선하였으며, 같은 서비스를 찾는 방법의 개선도 제안하고 있다. 이를 바탕으로 품질 기반의 장애 극복 웹 서비스 시스템을 구축할 수 있는 방안을 제시한다.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2004.05a
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• pp.356-359
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• 2004

한국증권산업은 최근 5년 동안 증권서비스의 거래방식이 오프라인에서 온라인으로 전환되는 급격한 패러다임의 변화를 겪었다. 이는 온라인 증권서비스가 오프라인에서 제공해 주지 못했던 서비스를 제공해 주었기 때문인 것으로 많은 연구를 통해 밝혀 졌다. 또한 정보통신기술의 급격한 발달과 모바일 기기의 빠른 보급으로 인하여 또다시 증권서비스의 거래 방식이 모바일기기를 이용한 방식으로 점차적으로 전환 될 것이라는 전망이 많이 예측 되었다. 그러나 전문가들이 예상했던 것과는 달리 모바일 증권서비스의 확산 속도는 2003년 온라인 증권 거래 방식 중 모바일 증권서비스의 거래방식이 3% 미만의 비중을 차지하는 등, 그 확산 속도가 정체되거나 매우 느리게 진행되고 있는 실정이다. 이에 본 연구에서는 초기에 많은 전문가들이 예상했던 모바일증권서비스가 활성화 되지 않는 요인을 장애요인으로 정의하고, 사용자들이 모바일증권서비스의 수용의도에 있어서 무엇이 가장 큰 장애요인 인지를 도출해 내고 도출된 장애요인을 실제 온라인 증권서비스 사용자들에게 검증 받는데 그 연구목적이 있다.

• 한국HCI학회:학술대회논문집
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• 2007.02a
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• pp.1069-1074
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• 2007

청각장애인이 PC환경에서 영화, 방송, 애니메이션 등의 동영상 콘텐츠를 이용할 때 장애의 정도에 따라 콘텐츠의 접근성에 있어서 시각적 수용 이외의 부분적 장애가 발생한다. 이러한 장애의 극복을 위해 수화 애니메이션이나 독화 교육과 같은 청각장애인의 정보 접근성 향상을 위한 콘텐츠와 기술이 개발된 사례가 있었으나 다소 한계점을 가지고 있다. 따라서 본 논문에서는 현대 뉴미디어 예술 작품의 예술적 표현 방법을 구성요소로서 추출하여, 기술과 감성의 조화가 어우러진 독창적인 콘텐츠를 생산할 수 있는 기술을 개발함으로써 PC환경에서 청각장애인의 동영상 콘텐츠에 대한 접근성 향상 방법을 추출하고, 실질적으로 청각적 효과의 시각적 변환 인터페이스 개발 및 이미지 캡션 생성 소프트웨어 개발을 통해 청각장애인의 동영상 콘텐츠 사용성을 극대화시킬 수 있는 방법론을 제시하고자 한다. 본 논문에서는 첫째, 청각장애인의 동영상 콘텐츠 접근성 분석, 둘째, 미디어아트 작품의 선별적 분석 및 유동요소 추출, 셋째, 인터페이스 및 콘텐츠 제작의 순서로 단계별 방법론을 제시하고 있다. 이 세번 째 단계에서 이미지 캡션 생성 소프트웨어가 개발되고, 비트맵 아이콘 형태의 이미지 캡션 콘텐츠가 생성된다. 개발한 이미지 캡션 생성 소프트웨어는 사용성에 입각한 일상의 언어적 요소와 예술 작품으로부터 추출한 청각 요소의 시각적요소로의 전환을 위한 인터페이스인 것이다. 이러한 기술의 개발은 기술적 측면으로는 청각장애인의 다양한 웹콘텐츠 접근 장애를 개선하는 독창적인 인터페이스 추출 환경을 확립하여 응용영역을 확대하고, 공학적으로 단언된 기술 영역을 콘텐츠 개발 기술이라는 새로운 영역으로 확장함으로써 간학제적 시도를 통한 기술영역을 유기적으로 확대하며, 문자와 오디오를 이미지와 시각적 효과로 전환하여 다각적인 미디어의 교차 활용 방안을 제시하여 콘텐츠를 형상화시키는 기술을 활성화 시키는 효과를 거둘 수 있다. 또한 청각장애인의 접근성 개선이라는 한정된 영역을 뛰어넘어 국가간 언어적인 장벽을 초월할 수 있는 다각적인 부가 동영상 콘텐츠에 대한 시도, 접근, 생산을 통해 글로벌 시대에 부응하는 새로운 방법론으로 발전 할 수 있다.

• Journal of Chest Surgery
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• v.36 no.8
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• pp.559-565
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• 2003

By improving the flow pattern in Fontan circuit, total cavopulmonary connection (TCPC) could result in a better outcome than atriopulmonary connection Fontan operation. For the patients with impaired hemodynamics after atriopulmonary Fontan connection, conversion to TCPC can be expected to bring hemodynamic and functional improvement. We studied the results of the revision of the previous Fontan connection to TCPC in patients with failed Fontan circulation. Material and method: From October1979 to June 2002, eight patients who had failed Fontan circulation, underwent revision of previous Fontan operation to TCPC at Yonsei University Hospital. Intracardiac anomalies of the patients were tricuspid atresia (n=4) and other functional single ventricles (n=4). Mean age at TCPC conversion was 14.0$\pm$7.0 years (range, 4.6~26.2 years) and median interval between initial Fontan operation and TCPC was 7.5 years (range, 2.4~14.3 years). All patients had various degree of symptoms and signs of right heart failure. NYHA functional class was 111 or IV in six patients. Paroxysmal atrial fibrillation (n:f), cyanosis (n=2), intraatrial thrombi (n=2), and protein losing enteropathy (PLE) (n=3) were also combined. The previous Fontan operation was revised to extracardiac conduit placement (n=7) and intraatrial lateral tunnel (n=1). Result: There was no operative death. Major morbidities included deep sternal infection (n=1), prolonged pleural effusion over two weeks (n=1), and temporary junctional lachyarrhythrnia (n=1). Postoperative central venous Pressure was lower than the preoperative value (17.9$\pm$3.5 vs. 14.9$\pm$1.0, p=0.049). Follow-up was complete in all patients and extended to 50,1 months (mean, 30.3$\pm$ 12.8 months). There was no late death. All patients were in NYHA class 1 or 11. Paroxysmal supraventricular tachycardia developed in a patient who underwent conversion to intraatrial lateral tunnel procedure, PLE was recurred in two patients among three patients who had had PLE before the convertsion. There was no newly developed PLE. Conclusion: Hemodynamic and functional improvement could be expected for the patients with Fontan circulatory failure after atriopulmonary connection by revision of their previous circulation to TCPC. The conversion could be performed with low risk of morbidity and mortality.

• The Journal of the Korea Contents Association
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• v.15 no.7
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• pp.664-673
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• 2015

The assistive devices for disabled people are being highlighted even in industrial aspects through the policy and support for disabled people, enactment of regulation for the improvement of accessibility of disabled, technological innovation and product development. Recently, internet access with the sense of touch and hearing and utilizing electronic publishing contents and e-mailing are being convenient through the product of ICT development such as screen reader for visually impaired people, braille display, screen enlarger, text converter and others. Even so, in rapidly changing digital media smart era, the accessibility of visually impaired people is still poor and assistive devices and alternative formats are in need of improvement. Therefore, in aspect of the research and development innovation, this study proposes the implementation directions for improvement of accessibility by analyzing the current situation and structure of alternative formats and assistive devices for visually impaired people. As a result, in the future, various types of digital information are expected to be converted into a customized and realistic forms and distributed through a dedicated disability products or smart devices.