• Journal of Korean Society of Steel Construction
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• v.17 no.6 s.79
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• pp.689-697
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• 2005

Recent test results on reduced beam section (RBS) steel moment connections show that specimens with a bolted web connection tend to perform poorly due to premature brittle fracture of the beam flange at the weld access hole. A review of previous test results indicates that the higher incidence of base metal fracture in bolted-web specimens is related, at least in part, to the web bolt slippage and the high stress concentration at the weld access hole with the lowest material toughness. The practice of providing web bolts uniformly along the beam depth based on the classical beam theory is questioned in this paper. A new seismic design procedure, which is more consistent with the actual load path identified from the analytical and experimental studies, is proposed together with improved connection details. A test specimen designed following the proposed procedure exhibited a cyclic connection rotation capacity sufficient for special moment frames without fracture.

• Archives of design research
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• v.18 no.3 s.61
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• pp.45-54
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• 2005

Visual messages are fundamental elements for performing communication and indicate the signs which are delivered from the communicator to the communicatee via channels, Generally, we can classify visual messages into two groups; linguistic factors which are rational and deliver abstract concepts and unlinguistic factors which are mental and can be expressed concretely. Especially, web site with receivers' low attention and concentration need images which can attract their attention to visual messages. That is, web site is a medium which allows us to feel visual and emotional experiences. We can call it a standard of sign systems which are consisted of various styles of digital texts. The main purpose of this study lies in that we'll analyze how homepage introductory page as one of the forms of digital text conduces a meaning action to the receivers and that we'll apprehend the structures of images and different types of signs via a semiotic approach and analyze the underlying meaning of the messages. In order to survey the structures of images we'll look into the attitude toward perceiving messages by using semantic differential method which has been developed mostly by Osgood and analyze the visual images by adopting sign types of Fuss. As the signification is created by combining signs, it is significant that we'll analyze the meaning of sings between the transmitters and receivers from the semiotic viewpoint and study the signification systems.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.19 no.4
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• pp.470-476
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• 2008

In this paper, we describe the cause of TDMA noise and distinction method of TDMA noise source in a GSM mobile phone. The causes of TDMA noise are composed of RF(Radio Frequency) energy coupling and low frequency energy coupling by burst ripple. We propose the distinction method of TDMA noise source from output(TDMA noise measurement) and frequency response of a system(audio path). Especially we propose a method of insertion loss($S_{21}$) analysis and the improvement method for RF energy coupling. Capacitor(40 pF) is a solution to reduce RF energy coupling and therefore TDMA noise was reduced by 10 dB.

• Journal of the Korean Society for Nondestructive Testing
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• v.27 no.1
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• pp.1-7
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• 2007

As fiber reinforced composite materials are widely used in aircraft, space structures and robot arms, the study on non-destructive testing methods has become an important research area for improving their reliability and safety. AE (acoustic emission) can evaluate the defects by detecting the emitting strain energy when elastic waves are generated by the initiation and growth of crack, plastic deformation, fiber breakage, matrix cleavage, or delamination. In the paper, AE signals generated under uniaxial tension were measured and analyzed using the $8{\times}8$ matrix piezo electric sensor. The electronic circuit to control the transmitting distance of AE signals was designed and constructed. The optical data storage system was also designed to store the AE signal of 64channels using LED (light emitting diode) elements. From the tests, it was shown that the source location and propagation path of AE signals in composite materials could be detected effectively by the $8{\times}8$ matrix piezo electric sensor.

• Journal of the Society of Disaster Information
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• v.19 no.1
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• pp.161-172
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• 2023

Safety education delivered to construction workers in a lecture manner has limitations in concentration and immersion, so delivery power and interest are low. In order to improve unstable behavior through education and prevent safety accidents, it is necessary to change the paradigm to hands-on education. Purpose: Experiential safety education aims to contribute to preventing accidents for construction workers by quickly recognizing risks, improving emergency response skills, and verifying the effectiveness of pre- and post-learning. Method: Based on a survey of workers who experienced the same work environment as the actual construction site, an opinion survey on the pre- and post-safety experience education and a variable measurement tool were planned, and a research hypothesis was established. Results: The Bayesian theory and MC simulation analysis were used to analyze the structural equation model, and the change in construction worker behavior was confirmed through the intended safety (A), non-experiential education in the sub-area of anxiety (B), average, standard deviation, and minimum and maximum values. Conclusion: The effect of education and industrial accidents are reduced only when construction workers are motivated to participate.

• Journal of the Korean Society of Radiology
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• v.16 no.5
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• pp.603-609
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• 2022

The dose distribution in the human body was evaluated and analyzed through dosimetry data using water phantom, ionization chamber and simulated by Monte Carlo simulation for ^99mTc and ¹⁸F sources, which are frequently used in the nuclear medicine in this study. As a result of this study, it was found that the dose decreased exponentially as the distance from the radioisotope increased, and it particularly showed a tendency to decrease sharply when the radioisotope was separated by 5 cm. It means that a large amount of dose is delivered to an organ located within 4 cm of source's movement path when a source uptake in the human body. Numerically, it was formed in the rage of 0.16 to 2.16 pC/min for ^99mTc and 0.49 to 9.29 pC/min for ¹⁸F. In addition, the energy transfer coefficient calculated using the result was found to be similar to the measured value and the simulation value in the range of 0.240 to 0.260. Especially, when the measured data and the simulation value were compared, there was a difference is within 2%, so the reliability of the data was secured. In this study, the distribution of radiation generated from a source was calculated to quantitatively evaluate the internal dose by radioisotopes. It presented reliable results through comparative analysis of the measurement value and simulation value. Above all, it has a great significance to the point that it was presented by directly measuring the distribution of radiation in the human body.

• Journal of Periodontal and Implant Science
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• v.34 no.4
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• pp.807-818
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• 2004

산화질소는 생리적 농도에서 세포내 신호전달자로 작용하지만 높은 농도에서는 세포독성을 일으킨다. 최근 치은 섬유아세포와 치주인대 섬유아세포는 산화질소 합성효소를 가지고 있고 세균의 lipopolysaccharide나 cytokine에 의해 대량의 높은 농도의 산화질소가 합성된다는 보고가 있음에도 지금까지 치은 조직에서 산화질소의 세포독성에 대한 연구는 아직 이루어 지지않고 있다. 본 연구는 사람의 치은 섬유아세포에서, 산화질소유도세포 고사기전을 밝히는데 목적이 있다. 세포 생장력은 MTT 방법으로 측정하였고, 세포의 형태적 변화는 Diff-Quick 염색법으로 조사하였다. Bcl-2 famly와 Fas 발현 정도는 RT-PCR 방법에 의해 확인하였으며, caspase-3, -8 와 -9의 활성은 spectrophotometer로 reactive oxygen species (ROS)는 형광분광계에 의해 측정되었다. 미토콘드리아에서 세포질로 분비된 cytochrome c는 western blot으로 조사하였다. 산화질소 유리제인 sodium nitroprusside (SNP) 처리는 사람 섬유아세포의 생존률을 시간과 농도 의존적으로 감소시켰고, 세포용적축소, 염색사 용축, DNA 절편화를 일으켰다. 또한, SNP 처리로 미토콘드리아에서 세포질로 유리되는 cytochrome c 양이 증가되었고, caspase-9 과 caspase-3 의 활성이 증가되었다. 한편, SNP 처리에 의해 death receptor 구성요소인 Fas 발현이 증가되었고, caspase-8의 활성이 증가되었다. Bcl-2 family 에 대한 RT-PCR 분석결과, 세포고사를 억제하는 Bcl-2 발현은 감소되었으나 세포고사를 자극하는 Bax와 Bid의 발현은 증가되었다. Soluble guanylate cyclase 억제제인 ODQ는 SNP에 의한 세포 생존율 감소를 차단하지 못했다. 따라서, 본 실험의 결과들은 사람 섬유아세포에서 산화질소유도 세포고사에 Bcl-2 family나 ROS가 매개하는 미토콘드리아 의존 및 death receptor 의존 세포고사기전이 관여함을 시사하였다.

• Clinical and Experimental Pediatrics
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• v.52 no.2
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• pp.213-219
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• 2009

Purpose:Iron is a critical nutritional element that is essential for a variety of important biological processes, including cell growth and differentiation, electron transfer reactions, and oxygen transport, activation, and detoxification. Iron is also required for neoplastic cell growth due to its catalytic effects on the formation of hydroxyl radicals, suppression of host defense cell activities, and promotion of cancer cell multiplication. Chronic transfusion-dependent patients receiving chemotherapy may have iron overload, which requires iron-chelating therapy. We performed this study to demonstrate whether the iron chelating agent deferoxamine induces apoptosis in Saos-2 osteosarcoma cells, and to investigate the underlying apoptotic mechanism. Methods:To analyze the apoptotic effects of an iron chelator, cultured Saos-2 cells were treated with deferoxamine. We analyzed cell survival by trypan blue and crystal violet analysis, apoptosis by nuclear condensation, DNA fragmentation, and cell cycle analysis, and the expression of apoptotic related proteins by Western immunoblot analysis. Results:Deferoxamine inhibited the growth of Saos-2 cell in a time- and dose-dependent manner. The major mechanism for growth inhibition with the deferoxamine treatment was by the induction of apoptosis, which was supported by nuclear staining, DNA fragmentation analysis, and flow cytometric analysis. Furthermore, bcl-2 expression decreased, while bax, caspase-3, caspase-9, and PARP expression increased in Saos-2 cells treated with deferoxamine. Conclusion:These results demonstrated that the iron chelating agent deferoxamine induced growth inhibition and mitochondrial-dependent apoptosis in osteosarcoma Saos-2 cells, suggesting that iron chelating agents used in controlling neoplastic cell fate can be potentially developed as an adjuvant agent enhancing the anti-tumor effect for the treatment of osteosarcoma.

• Journal of Korean Society of Transportation
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• v.22 no.7 s.78
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• pp.119-129
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• 2004

This paper is designed to report the results of development and validation procedures in relation to the Freeway Incident Management System (FIMS) prototype development as part of Intelligent Transportation Systems Research and Development program. The central core of the FIMS is an integration of the component parts and the modular, but the integrated system for freeway management. The whole approach has been component-orientated, with a secondary emphasis being placed on the traffic characteristics at the sites. The first action taken during the development process was the selection of the required data for each components within the existing infrastructure of Korean freeway system. After through review and analysis of vehicle detection data, the pilot site led to the utilization of different technologies in relation to the specific needs and character of the implementation. This meant that the existing system was tested in a different configuration at different sections of freeway, thereby increasing the validity and scope of the overall findings. The incident detection module has been performed according to predefined system validation specifications. The system validation specifications have identified two component data collection and analysis patterns which were outlined in the validation specifications; the on-line and off-line testing procedural frameworks. The off-line testing was achieved using asynchronous analysis, commonly in conjunction with simulation of device input data to take full advantage of the opportunity to test and calibrate the incident detection algorithms focused on APID, DES, DELOS and McMaster. The simulation was done with the use of synchronous analysis, thereby providing a means for testing the incident detection module.

• Journal of dental hygiene science
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• v.14 no.4
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• pp.580-588
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• 2014

Fluoride use is the best and widespread method for dental caries prevention. The aim of this study was to investigate experience and recognition of fluoride for caries prevention focusing on majors in one university. Four hundred twenty-four university students were selected by convenience sampling with informed consent and answered the questionnaire by self recording type. The subjects except dental hygiene students knew about purpose of fluoride use (84.6%), over the count fluoride rinse (63.2%), fluoride toothpaste (61.5%), professional fluoride application (56.4%) and water fluoridation (43.6%). They experienced over the count fluoride rinse (67.5%), school fluoride rinse (45.3%), professional fluoride application (30.8%), fluoride toothpaste (28.2%) and water fluoridation (12.0%). The main information paths about fluoride were university lectures among dental hygiene students and internet and mass media, followed by nurse-teachers among non dental hygiene students. The ratios of intention to use fluoride were: 67.8% in dental hygiene, 34.9% in health, 51.4% in non-health in case of professional fluoride application for oneself, 93.1% in dental hygiene, 48.0% in health, 50.4% in non-health in case of professional fluoride application for their children, 79.0% in dental hygiene, 51.3% in health, 55.8% in non-health in case of water fluoridation. The subjects to experience and recognize fluoride for caries prevention had more positive intention to use fluoride. The answers of students majoring in health or medical care were not different from non-health, except dental hygiene. Dental professionals should try to let the public know about fluoride use for caries prevention through mass media and internet as well as individual education in dental clinics.