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Effect of Ischemic Preconditioning for Preventing Ischemic Injury of the Spinal Cord (척추 신경의 허혈성 손상 예방을 위한 허혈성 전처치의 효과)

  • 홍종면;차성일;송우익;홍장수;임승운;임승운;임승평
    • Journal of Chest Surgery
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    • v.34 no.11
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    • pp.823-830
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    • 2001
  • Background: Paraplegia is a serious complication of thoracic or thoracoabdominal aortic operations, which is related to ischemic injury of the spinal cord induced by low perfusion pressure during cross clamping of the aorta. Ischemic preconditioning of heart or brain with reversible sublethal ischemic injury induces resistance to subsequent lethal ischemia. The aim of this study is to investigate whether ischemic tolerance could be induced by the preconditioning of the spinal cord using swine model. Material and Method: The animals were randomly assigned to three groups: sham group(n=3), control group(n=6) and pre-conditioning group(n=8). In the sham group, we performed the left thoracotomy only without any ischemic injury. In the preconditioning group, the swine received reversible spinal cord ischemic injury by aortic clamping for 20 minutes, whereas control group had no previous aortic cross- clamping. Forty-eight hours later, the aorta was clamped for 30 minutes in both groups. Neurological examination was done 24 hours later, then the animals were euthanized for histopathology and malonedialdehyde(MDA) spectrophotometry assay of the spinal cord. Result: Statistically significant difference in neurological outcome was observed between the control and preconditioning groups at 24 hours after ischemic injury. The incidence of paraplegia and severe paresis was 100% in the control group, and 62.5% in the preconditing group(p=0.028). There was no statistically significant difference in histopathology and MDA assay of the ischemic spinal cord between these two groups with borderline statistical difference in MDA assay(p=0.0745). Conclusion: In the present swine study, ischemic preconditioning could induce tolerance against 30 minute ischemic insult of the spinal cord, although the animals did not completely recover(stand-up or walk). We expect that combining this preconditioning with other currently existing protection methods might lead to a synergistic effect, which warrants further investigation.

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The Definition of Connecting Flight and Extraterritorial Application of Regulation (EC) No 261/2004: A Case Comment on Claudia Wegener v. Royal Air Maroc SA [2018] Case C-537/17 (EC 261/2004 규칙의 역외적용과 연결운항의 의미 - 2018년 EU사법재판소 Claudia Wegener v. Royal Air Maroc SA 판결의 평석 -)

  • Sur, Ji-Min
    • The Korean Journal of Air & Space Law and Policy
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    • v.35 no.1
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    • pp.103-125
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    • 2020
  • This paper reviews the EU Case, Claudia Wegener v. Royal Air Maroc SA [2018] ECLI:EU:C:2018:361, Case C-537/17. It analyzes some issues as to Wegener case by examining EU Regulations and practical point of views. Article 3(1)(a) of Regulation (EC) No 261/2004 of the European Parliament and of the Council of 11 February 2004 establishing common rules on compensation and assistance to passengers in the event of denied boarding and of cancellation or long delay of flights, entitled scope, provides: "this Regulation shall apply: (a) to passengers departing from an airport located in the territory of a Member State to which the Treaty applies; (b) to passengers departing from an airport located in a third country to an airport situated in the territory of a Member State to which the Treaty applies, unless they received benefits or compensation and were given assistance in that third country, if the operating air carrier of the flight concerned is a Community carrier." ECJ held that must be interpreted as meaning that Regulation (EC) No 261/2004 applies to a passenger transport effected under a single booking and comprising, between its departure from an airport situated in the territory of a Member State and its arrival at an airport situated in the territory of a third State, a scheduled stopover outside the European Union with a change of aircraft. According to the Court, it is apparent from the regulation and case-law that when, as in the present case, two (or more) flights are booked as a single unit, those flights constitute a whole for the purposes of the right to compensation for passengers. Those flights must therefore be considered as one and the same connecting flight.

Development and Comparison of Growth Regression Model of Dry Weight and Leaf Area According to Growing Days and Accumulative Temperature of Chrysanthemum "Baekma" (국화 "백마"의 생육 일수 및 누적 온도에 따른 건물중과 엽면적의 생장 회귀 모델 개발 및 비교)

  • Kim, Sungjin;Kim, Jeonghwan;Park, Jongseok
    • Journal of Bio-Environment Control
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    • v.29 no.4
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    • pp.414-420
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    • 2020
  • This study was carried out to investigate the growth characteristics of standard chrysanthemum 'Baekma', such as fresh weight, dry weight, and leaf area and to develop prediction models for the production greenhouse based on the growth parameters and climatic elements. Sigmoid regressions models for the prediction of growth parameters in terms of dry weight and leaf area were analyzed according to the number of the day after transplanting and the accumulate temperature during this experimental period. The relative growth rate (RGR) of the chrysanthemum was 0.084 g·g-1·d-1 on average during the period.The dry weight and leaf area of 'Beakma' increased exponentially according to the number of day after transplanting and the accumulated temperature, in the case of dry weight increased by an average of 39.1% until 63 days (accumulated temperature of 1601℃), after that dry weight increased by an average of 7.4% before harvest. The leaf area increased by an average of 63.3% until the 28th day after transplanting, and by an average of 6.5% until the 84th day before flower bud differentiation occurred, and increased by an average of 10.6% before harvest. This experiment can be used as a useful data for establishing a cultivation management system and a planned year-round production system for standard chrysanthemum "Baekma". To make a more precise growth prediction model, it will need to be corrected and verified based on various weather data including accumulated irradiation.

Performance Estimation of Large-scale High-sensitive Compton Camera for Pyroprocessing Facility Monitoring (파이로 공정 모니터링용 대면적 고효율 콤프턴 카메라 성능 예측)

  • Kim, Young-Su;Park, Jin Hyung;Cho, Hwa Youn;Kim, Jae Hyeon;Kwon, Heungrok;Seo, Hee;Park, Se-Hwan;Kim, Chan Hyeong
    • Journal of Radiation Protection and Research
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    • v.40 no.1
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    • pp.1-9
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    • 2015
  • Compton cameras overcome several limitations of conventional mechanical collimation based gamma imaging devices, such as pin-hole imaging devices, due to its electronic collimation based on coincidence logic. Especially large-scale Compton camera has wide field of view and high imaging sensitivity. Those merits suggest that a large-scale Compton camera might be applicable to monitoring nuclear materials in large facilities without necessity of portability. To that end, our research group have made an effort to design a large-scale Compton camera for safeguard application. Energy resolution or position resolution of large-area detectors vary with configuration style of the detectors. Those performances directly affect the image quality of the large-scale Compton camera. In the present study, a series of Geant4 Monte Carlo simulations were performed in order to examine the effect of those detector parameters. Performance of the designed large-scale Compton camera was also estimated for various monitoring condition with realistic modeling. The conclusion of the present study indicates that the energy resolution of the component detector is the limiting factor of imaging resolution rather than the position resolution. Also, the designed large-scale Compton camera provides the 16.3 cm image resolution in full width at half maximum (angular resolution: $9.26^{\circ}$) for the depleted uranium source considered in this study located at the 1 m from the system when the component detectors have 10% energy resolution and 7 mm position resolution.

Maximum Stem Number and Mortality Model for Even-Aged Pinus Densiflora Stand in Kangwon-Province, Korea (강원도지방(江原道地方) 소나무 동령임분(同齡林分)의 최대임목본수(最大林木本數) 및 고사(枯死)모델)

  • Lee, Woo-Kyun;Seo, Jeong-Ho;Bae, Sang-Won
    • Journal of Korean Society of Forest Science
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    • v.89 no.5
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    • pp.634-644
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    • 2000
  • Sterba's theory that stem number maintaining maximum basal area per ha is maximum stem number of a stand, had been applied to data from 103 temporary plots in even-aged Pinus densiflora stands in Kangwon province, Korea and a maximum stem number and mortality model was prepared. DBH growth model which estimates dbh with the independent variables of stem number per ha and dominant height shows the good statistical performance, and explains well differences in dbh growth that would be caused by stem number per ha and dominant height. Basal area model derived from dbh growth model also explains well differences in basal area according to stem number per ha and dominant height. The maximum stem number curve, which is derived from stem number per ha at maximum basal area for dominant height and dbh, represents well the upper range of stem number per ha observed. And maximum stand density index derived from the maximum stem number model for dbh could be used for the index of maximum potential density of a stand. The maximum stem number model and maximum stand density index in this study were not based on stand data with maximum density but based on the temporary data from stands with various density. This maximum stem number model can be applied to the estimation of mortality and maximum potential volume.

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Attack Capability Analysis for Securing Self-Survival of Air Defense Weapons (대공방어무기의 자기생존성 확보를 위한 공격능력분석)

  • Kim, Sea Ill;Shin, Jin
    • Journal of the Korea Society for Simulation
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    • v.30 no.3
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    • pp.11-17
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    • 2021
  • The 30mm anti-aircraft gun has been developed with various types of weapon systems such as protective, protective complex, and wheel-type anti-aircraft artillery. The role of this anti-aircraft gun is an important anti-aircraft weapon in charge of air defense. Anti-aircraft weapons are tasked with defending the airspace from aircraft attacks. In particular, anti-aircraft weapons are organized in combination with mechanized units. And anti-aircraft weapons are prone to attack by enemies because they operate on the front lines of the battlefield. The enemy is expected to attack our troops by covering up or concealing as much as possible in order to increase their viability. Therefore, this study analyzed whether our 30mm anti-aircraft bullets could subdue the enemy in cover. This study analyzed the performance of 30mm anti-aircraft bullets using the M&S technique. For this study, live shooting and simulation method by M&S were used for the experiment. In this study, steel plate and plywood were used for the live shooting experiment. In addition, in the simulation process through M&S, this study used the PRODAS model, AUTODYN model, and Split-x model to analyze the trajectory, penetration, and fragmentation capability of 30mm anti-aircraft bullets. According to the experimental results, it has been proven that 30mm anti-aircraft bullets can destroy enemy armored vehicles. 30mm anti-aircraft bullets succeeded in quickly subduing enemies concealed in general buildings or forests. In this way, it was possible to minimize damage to allies in advance.

Estimation and Validation of the Leaf Areas of Five June-bearing Strawberry (Fragaria × ananassa) Cultivars using Non-destructive Methods (일계성 딸기 5품종의 비파괴적 방법을 사용한 엽면적 추정 및 검증)

  • Jo, Jung Su;Sim, Ha Seon;Jung, Soo Bin;Moon, Yu Hyun;Jo, Won Jun;Woo, Ui Jeong;Kim, Sung Kyeom
    • Journal of Bio-Environment Control
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    • v.31 no.2
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    • pp.98-103
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    • 2022
  • Non-destructive estimation of leaf area is a more efficient and convenient method than leaf excision. Thus, several models predicting leaf area have been developed for various horticultural crops. However, there are limited studies on estimating the leaf area of strawberry plants. In this study, we predicted the leaf areas via nonlinear regression analysis using the leaf lengths and widths of three-compound leaves in five domestic strawberry cultivars ('Arihyang', 'Jukhyang', 'Keumsil', 'Maehyang', and 'Seollhyang'). The coefficient of determination (R2) between the actual and estimated leaf areas varied from 0.923 to 0.973. The R2 value varied for each cultivar; thus, leaf area estimation models must be developed for each cultivar. The leaf areas of the three cultivars 'Jukhyang', 'Seolhyang', and 'Maehyang' could be non-destructively predicted using the model developed in this study, as they had R2 values over 0.96. The cultivars 'Arihyang' and 'Geumsil' had slightly low R2 values, 0.938 and 0.923, respectively. The leaf area estimation model for each cultivar was coded in Python and is provided in this manuscript. The estimation models developed in this study could be used extensively in other strawberry-related studies.

Development of Radiation Image Sensor using Heterojunction (이종접합을 이용한 방사선 영상 센서 개발)

  • Kim, Young-Bin;Yun, Min-Seok;Kim, Min-Woo;Jung, Suk-Hee;Kim, Yoon-Suk;Oh, Kyung-Min;Nam, Sang-Hee;Park, Ji-Koon
    • Journal of the Korean Society of Radiology
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    • v.3 no.3
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    • pp.27-35
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    • 2009
  • In this study, the basic research verifying possibility of applications as radiology image sensor in Digital Radiography was performed, the radiology image sensor was fabricated using double layer technique tio decrease dark current. High efficiency material in substitution for a-Se have been studied as a direct method of imaging detector in Digital Radiography to decrease dark current by using Hetero junction already used as solar cell, semiconductor. Particle-In-Binder method is used to fabricate radiology image sensor because it has a lot of advantages such as fabrication convenient, high yield, suitability for large area sensor. But high leakage current is one of main problem in PIB method. To make up for the weak points, double layer technique is used, and it is considered that high efficient digital radiation sensor can be fabricated with easy and convenient process. In this study, electrical properties such as leakage current, sensitivity is measured to evaluate double layer radiation sensor material.

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Structure and Dynamics of Quercus acuta, Quercus acutissima and Pinus rigida Forests in Wando Island (완도지역 붉가시나무림, 상수리나무림, 리기다소나무림의 구조와 동태)

  • Park, In-Hyeop
    • Korean Journal of Environment and Ecology
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    • v.26 no.3
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    • pp.406-411
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    • 2012
  • Structure and dynamics for three type forests of Quercus acuta, Quercus acutissima and Pinus rigida forests were studied in Wando island, Korea. Quercus acuta and Quercus acutissima forests were natural forest and Pinus rigida forest was a about 30-year-old plantation. Density of tree layers of Quercus acuta, Quercus acutissima and Pinus rigida forests was 2,250 trees/ha, 760 trees/ha, and 1,560 trees/ha, respectively. Mean DBH of tree layers of Quercus acuta, Quercus acutissima and Pinus rigida forests was 12.1 cm, 14.3 cm, and 14.1 cm, respectively. Total basal area of tree layer and subtree layer was $37.1m^2/ha$ for Quercus acuta forest, $19.0m^2/ha$ for Quercus acutissima forest, and $29.2m^2/ha$ for Pinus rigida forest, respectively. According to importance percentage, Camellia japonica was the first dominant species in subtree and shrub layers of all of Quercus acuta, Quercus acutissima and Pinus rigida forests. Species diversity(H') of forest total was 0.814 for Quercus acuta forest, 0.956 for Quercus acutissima forest, and 0.866 for Pinus rigida forest, respectively. According to diameter distribution, Quercus acuta forest was supposed to remain unchanged for a long time. Quercus acutissima forest was changing to Camellia japomica forest and Pinus rigida forest was changing to Quercus acuta-Camellia japonica forest.

Field Mapping based on Virtual Office for Real time GIS in Field Survey for Natural Environment (자연환경조사에서 실시간 GIS구현을 위한 가상사무실 기반의 필드멥핑)

  • 엄정섭;김희두
    • Spatial Information Research
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    • v.9 no.1
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    • pp.51-72
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    • 2001
  • It is frequently pointed out that the conventional field survey for natural environment has may limitations in terms of positional accuracy, real-time GIS data acquisition, and economic efficiency. The aim of this research was to develop an on site real-time mapping technique that enables the surveyor to input data in the field. The idea is based upon the recent trends in the field of Telecommunication and Information Technology that uses a GPS, wireless network computing, moving computing, etc. A virtual office approach has been adopted, in which a portable computer is linked to a GPS and field workers record data on the computer at the site and analyse data on site. This field mapping system has shown to be much less susceptible to the positional accuracy than that of th conventional approach. The Graphic User Interface, in particular, were ideally suited to combining positional information with attribute data which changes with every survey points. This interface allows users to interactively display and query GIS layers reproduced from the past survey results. The GIS database stored in the virtual office will serve to carry out a highly reliable survey since it could play a crucial role in identifying temporal and spatial changes occurred in the site. It is expected that integrated utilization of field data among the related agencies would be increased much more than before since the virtual office survey would be a powerful tool to ensure geometric fidelity in GIS database creation process. This paper also discusses the limitations and future direction of the present prototype research.

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