• Journal of Life Science
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• v.21 no.7
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• pp.985-991
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• 2011

The purpose of this study was to investigate the biological effect of obesity-induced oxidative damage on neurogenesis and early protein expression. Obesity was induced I thirty 4-week old male Sprague-Dawley rats through a high fat diet for 15 weeks. After one week of environmental adaptation, the rats were divided into 2 groups: high fat diet sedentary group (HDS, n=15) and high fat diet training group (HDT, n=15). Exercise training was performed 5 times a week for 8 weeks, with mild-intensity treadmill running for weeks 1-4 and moderate-intensity treadmill running for weeks 5-8. After the 8 week training period, we analyzed lipid profiles, serum 8-hydroxyguanosine (8-OHdG), liver tissue malondialdehyde (MDA) related to oxidative damage factors, nerve growth factor (NGF), brain derived neurotrophic factor (BDNF), c-fos, c-jun, and extracellular signal regulated kinase (Erk) in the hippocampus. The results of this study are as follows. There were differences between HDS and HDT in triglyceride (TG) and total cholesterol (TC) (p<0.05). In high density lipoprotein (HDL-c), the HDT was higher than HDS after treadmill training (p<0.05). In 8-OHdG, the HDT was lower than HDS after treadmill training (p<0.05). Genetic expressions of c-jun, BDNF and MDA in the HDT were higher than in the HDS after treadmill training in hippocampus (p<0.05). Therefore, we conclude that 8 weeks of treadmill training can improve imbalanced lipid profiles, reduce oxidative damage, and activate neurogenesis in obese rats.

• Proceedings of the KGS Conference
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• 2002.05a
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• pp.77-80
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• 2002

본 논문의 연구목적은, 우리나라 감자재배지역의 분포 특징과 그 중심지를 밝혀 보는데 있다. 이와 같은 목적을 위하여 감자가 외국에서 우리나라에 전파해온 경로와 한국 내에서 의 전파경로를 알아보고, 7개 지역의 감자재배지역의 특징, 우리나라 감자재배의 생산량, 재배면적, 재배농가, 각 시기별 감자 재배지의 중심지와 남한의 감자재배 중심지를 구하였다. 이와 같은 연구내용은 주어진 자연환경에 인간이 어떻게 적응해가면서 살아가는지를 공부하는 지리학의 전통적인 개념인 자연과 인간과의 관계를 이해하는데 도움을 줄 수 있을 뿐만 아니라, 초 중등학교 및 대학에서 공부하는 한국지리 교육과정의 학습자료로서 유용하게 쓰일 수 있을 것으로 기대한다. 연구방법은 문헌연구과 1970년부터 1995년까지의 전국의 시.군별 감자재배지역의 입지계수를 구하여 연구하였다. 그 결과를 요약하면 다음과 같다. 1. 감자가 한국에 처음으로 재배된 것은 1824년(조선조 순조24년) 인데, 전파과정을 살펴보면, 안데스산지의 페루(1500년대) $\longrightarrow$ 에스파냐(1532년) $\longrightarrow$ 중국(1650년) $\longrightarrow$ 한국(1824년)순으로 전파되어온 북방전래설과 영국의 감자가 1832년 충청도의 서산으로, 일본 감자가 1920년에 수원으로 전파되었다는 남방전래설이 있다 2. 감자는 한국 전 지역에서 재배되는 중요 농작물이다 그러나 우리나라의 지형이 남북으로 깊게 뻗은 반도국이므로 위도와 지형 차이에 따라 기온과 고도가 다르게 나타나는데, 이러한 자연적인 요인의 영향이 가장 큰 요인이 되어 고랭지 여름재배지역.중산간 봄재배지역.중부평야 봄재배지역 남부평야 봄재배지역 남부해안 2기작 재배지역.남부 겨울재배지역.제주 가을 월동재배지역 등 7개 지역으로 구분되어 재배된다. 3. 우리나라(남한)의 감자 재배지의 중심지는 강원도 고랭지 여름재배지역과 제주도 가을 월동재배지역, 소백산맥과 진안고원이 만나는 부근 산지지역의 남원군.구례군 거창군.고령군과 남해안의 밀양군.양산군이다. 강원도 지역과 제주도 두지역이 전테 재배면적의 52%를 점유하여 감자 재배지의 핵심지를 이룬다. 4. 한국 감자 재배지역 중심지의 지리적 특징은, 높은 산지지역의 산록완사면에 밭작물로 재배된다는 점과 교통이 불편한 지역으로서 도시화와 산업화 지역의 그늘 지역이 대부분이다. 강원도의 감자 재배지는 감자재배에 적합한 자연환경과 화전농업의 전통, 감자 재배기술의 전파, 중앙정부와 지방정부가 지원하는 각종 연구소 분포와 영농지도, 씨감자 생산과 협동조합의 판로 개척, 도로 개설과 포장 등의 인문지리적 요인이 영농조건을 개선하고 감자 판매를 위한 시장접근을 용이하게 하여, 남한 최대의 감자 재배지역을 형성하였다. 제주도는 산지지형과 따뜻한 기온으로 2기작이 가능하고, 감자가공 공장설립과 교통발달에 따른 육지 시장과의 접근이 용이해졌기 때문에 남한에서 2번째로 큰 감자재배지역이 되었다.(요약 및 결론에서 발췌)

• Journal of Korea Water Resources Association
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• v.30 no.4
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• pp.347-355
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• 1997

In this study, the applicability of genetic algorithms into the parameter estimation of storage function method for flood routing model is investigated. Genetic algorithm is mathematically established theory based on the process of Darwinian natural selection and survival of fittest. It can be represented as a kind of search algorithms for optima point in solution space and make a reach on optimal solutions through performance improvement of assumed model by applying the natural selection of life as mechanical learning province. Flood events recorded in the Daechung dam are selected and used for the parameter estimation and verification of the proposed parameter estimation method by the split sample method. The results are analyzed that the performance of the model are improved including peak discharge and time to peak and shown that the parameter Rsa, and f1 are most sensitive to storage function model. Based on the analysis for estimated parameters and the comparison with the results from experimental equations, the applicability of genetic algorithm is verified and the improvements of those equations will be used for the augmentation of flood control efficiency.

• International Commerce and Information Review
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• v.14 no.2
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• pp.249-269
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• 2012

The focus of our work is to identify and understand the drivers of alliance performance so that businesses can maximize their chances of a successful alliance-an area that has received little attention in empirical modeling. Although both conceptual and applied research on alliances has increased, an empirically tested comprehensive theoretical model that explains alliance performance has yet to be developed. Using five salient perspective, namely market power theory, transaction cost theory, the resource-based view, institutional theory, real option theory, this paper attempts to provide a theoretical rationale linking motives of global alliance networks on firm's capabilities, partner's capabilities, operating structures, and performances of Korean companies. The key contribution of this study is that it paints a picture of what matters in driving alliance performance. Our work shows the complex nature of driving performance and the interplay of firm's capabilities, partner's capabilities, and operating structures for understanding alliance performances. This study has given us a small but significant step forward towards understanding the intricacies of alliance performance. We are now better able to understand the respective roles played by various alliance factors and derive insights that lead to improved alliance performance.

• Journal of Science Education
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• v.40 no.2
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• pp.116-130
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• 2016

The purpose of this study was to investigate the difficulties of science classes experienced by newly appointed elementary school teachers in terms of science content knowledge and teaching method, and to suggest some implications for their effective adaptation. We recorded science lessons conducted by 3 beginning elementary school teachers with less than 5 years experience and also analyzed their classes and interview materials. The results were as follows. First, difficulties that they experienced in science content knowledge was the possession of scientific errors or misconceptions, the lack of awareness and confidence in scientific concepts and principles, and the possession of negative concept about learning materials. Second, difficulties that they experienced in teaching method was the absence of reorganization of the textbook contents, using closed questions, one-sided instructions and explanations by teacher, the application of incomplete analogy, and the lack of understanding about experiment activities. The implication from this study is that beginning teachers need to be provided with curriculum oriented in experiment at teachers college and to participate in various types of educational opportunities.

• Journal of The Korean Association For Science Education
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• v.41 no.5
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• pp.415-428
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• 2021

The COVID-19 pandemic has changed everything, even education. Last year when distance learning was introduced, science teachers faced many challenges to overcome. However, teachers adapted quickly, and in this year, it became the 'new normal'. In this situation, teachers are likely to habitually repeat past practices, but the context of the second year of distance learning is changing constantly, and teachers are asked to interpret the problem occurring in a situation and to adjust their practice for solving the problem with their teacher agency. In this study, we explore the emergence of science teacher agency and factors shaping teacher agency in the second year of distance learning and we focus on teachers' agentic practice that did not follow their past practice without reflection. For this purpose, we mainly analyze the semi-constructed interview of three science teachers. In the first year of distance learning, two teachers maintained their practice, not much different to face-to-face learning. However, one teacher reflected upon herself and started to recognize and solve her problems. Reflection for her practice can support this process. Another teacher changed her practice due to external suggestions, but it evolved her practice to fit the situation better, and her experience of last year helped her to adapt to the change. The other teacher who modified her practice to persist her professional purpose last year was consistently practicing in the second year and collaboration and autonomy can support her. This study shows the teachers' dynamic change of agency and the emergence for the relational interaction between teacher and context.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.9 no.1
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• pp.845-858
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• 2019

The most serious problem company facing in today's business environment is the failure of new product development outcomes. Statistically, almost half of the new products released each year failed. Despite the innovative technological advances, consumers' expectation level become much higher and global competition is intensifying. In addition, the new product life cycle is becoming shorter and shorter. It is difficult for a company to survive without developing long-lived products. The most important issue in a company's success and failure is the successful development and introduction of new products. Previous research has presented many determinants to achieve a successful new product development. This study focuses on dynamic competence as an important determinant, and identifies the constituting elements. Enterprises need to acquire, absorb, integrate and reconfigure their resources to survive and develop continuously. It is necessary to hold a dynamic ability switching resource bases in order to adapt to changing environments. The results of this study are as follows: First, the effect of learning, reconfiguration, and alliance capabilities on the new product development of small and medium-sized manufacturing enterprises seems to be positive. Second, the integrative and reconfiguration capabilities positively affect a new product development under high environmental turbulence.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.11
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• pp.60-67
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• 2018

This study was conducted to investigate the effects of DISC behavioral style on the knowledge and clinical performance of nursing students. The subjects of the study were nursing students in the fourth grade of university and the data collection period was from March 2015 to December 2016. The collected data were analyzed using SPSS 24.0. DISC behavioral style analysis showed that 10.6% were dominant, 33.8% were influence, and 48.5% were steadiness and 7.1% were conscientiousness. Knowledge score in accordance with the measured points of DISC behavioral style did not show differences in the first, but did show differences in the second and third. Conversely, clinical performance score in accordance with the measurement points of DISC behavioral style showed differences in the first, second and third.Knowledge and clinical performance scores revealed significant differences in the interactions between the groups, between measurement points and between groups and measurement points. As a result, DISC behavioral style of nursing college students vary, with each having merits and demerits. Therefore, it is necessary to provide an opportunity to understand these points and to develop merits in order to improve the learning outcomes of the curriculum.

• Korean Journal of Child Education & Care
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• v.19 no.2
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• pp.85-100
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• 2019

Objective: The purpose of this study was to find out the effect of gratitude enhancement program for freshman on pre-service early childhood teacher's gratitude disposition, empathic ability, and department satisfaction. Methods: 55 freshmen majoring in early childhood education were participated in this study. Twenty-eight of them were classified as an experimental group and made to go through gratitude enhancement program for freshman. Twenty-seven of them were classified as a control group. The gratitude enhancement program for freshman consisted of lectures on cognitive, affective and behavioral gratitude factors. To verify the effect of this program, the tests on gratitude disposition, empathic ability, and department satisfaction were carried out and the collected data were analyzed by ANCOVA. Results: The result of this study was that the gratitude enhancement program was effective for improving gratitude disposition, empathic ability, and department satisfaction of pre-service early childhood teachers. Conclusion/Implications: This study illustrated the need of gratitude enhancement program and its methodologies for pre-service early childhood teacher's college adjustment and persistence by improving gratitude disposition, empathic ability, and department satisfaction.

• Science of Emotion and Sensibility
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• v.24 no.2
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• pp.39-48
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• 2021

According to International Associating for the Study of Pain (IASP) definition, neuropathic pain is a disorder characterized by dysfunction of the nervous system that, under normal conditions, mediates virulent information to the central nervous system (CNS). This pain can be divided into a disease with provable lesions in the peripheral or central nervous system and states with an incorporeal lesion of any nerves. Both conditions undergo long-term and chronic processes of change, which can eventually develop into chronic pain syndrome, that is, nervous system is inappropriately adapted and difficult to heal. However, the treatment of neuropathic pain itself is incurable from diagnosis to treatment process, and there is still a lack of notable solutions. Recently, several studies have observed the responses of CNS to harmful stimuli using image analysis technologies, such as functional magnetic resonance imaging (fMRI), positron emission tomography (PET), and optical imaging. These techniques have confirmed that the change in synaptic-plasticity was generated in brain regions which perceive and handle pain information. Furthermore, these techniques helped in understanding the interaction of learning mechanisms and chronic pain, including neuropathic pain. The study aims to describe recent findings that revealed the mechanisms of pathological pain and the structural and functional changes in the brain. Reflecting on the definition of chronic pain and inspecting the latest reports will help develop approaches to alleviate pain.