• Radiation Oncology Journal
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• v.28 no.2
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• pp.106-110
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• 2010

Reactivation of the hepatitis B virus (HBV) is a well-recognized complication in patients with chronic HBV infection who receive cytotoxic or other immunosuppressive therapy. In cases of patients treated by radiotherapy however, only a few of such reports exist and most of these include the patients previously treated by chemotherapy or transarterial chemoembolization. The results of this study point to a case of a patient with reactivation of HBV after radiotherapy alone. This study shows the possibility of HBV reactivation by partial hepatic irradiation alone hence, special attention should be paid to patients with HBV disease.

• Geophysics and Geophysical Exploration
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• v.9 no.1
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• pp.50-59
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• 2006

The risk of fault reactivation in the Gippsland Basin was calculated using the FAST (Fault Analysis Seal Technology) technique, which determines fault reactivation risk by estimating the increase in pore pressure required to cause reactivation within the present-day stress field. The stress regime in the Gippsland Basin is on the boundary between strike-slip and reverse faulting: maximum horizontal stress $({\sim}\;40.5\;Mpa/km)$ > vertical stress (21 Mpa/km) ${\sim}$ minimum horizontal stress (20 MPa/km). Pore pressure is hydrostatic above the Campanian Volcanics of the Golden Beach Subgroup. The NW-SE maximum horizontal stress orientation $(139^{\circ}N)$ determined herein is broadly consistent with previous estimates, and verifies a NW-SE maximum horizontal stress orientation in the Gippsland Basin. Fault reactivation risk in the Gippsland Basin was calculated using two fault strength scenarios; cohesionless faults $(C=0;{\mu}=0.65)$ and healed faults $(C=5.4;\;{\mu}=0.78)$. The orientations of faults with relatively high and relatively low reactivation potential are almost identical for healed and cohesionless fault strength scenarios. High-angle faults striking NE-SW are unlikely to reactivate in the current stress regime. High-angle faults oriented SSE-NNW and ENE-WSW have the highest fault reactivation risk. Additionally, low-angle faults (thrust faults) striking NE-SW have a relatively high risk of reactivation. The highest reactivation risk for optimally oriented faults corresponds to an estimated pore pressure increase (Delta-P) of 3.8 MPa $({\sim}548\;psi)$ for cohesionless faults and 15.6 MPa $({\sim}2262\;psi)$ for healed faults. The absolute values of pore pressure increase obtained from fault reactivation analysis presented in this paper are subject to large errors because of uncertainties in the geomechanical model (in situ stress and rock strength data). In particular, the maximum horizontal stress magnitude and fault strength data are poorly constrained. Therefore, fault reactivation analysis cannot be used to directly measure the maximum allowable pore pressure increase within a reservoir. We argue that fault reactivation analysis of this type can only be used for assessing the relative risk of fault reactivation and not to determine the maximum allowable pore pressure increase a fault can withstand prior to reactivation.

• Korean Journal of Construction Engineering and Management
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• v.10 no.3
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• pp.3-12
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• 2009

Community revitalization programs in New York State are community centralized projects, and this approach is pretty much general in the united states. However, local communities do not have enough funds, human resources, technical knowledge and useful data. Even though State governments have their own supporting systems, they are not able to support all that communities need and ask. State governments are, on the other hand, trying to develop the most efficient supporting system for the community revitalization programs as a part of community development. US federal government supports funds as well. New York state government makes connections with other states, local governments, universities, and other useful groups, and reorganizes all possible resources for New York state communities. This supporting system helps that local leaders and community residents can tackle regionally specific issues and opportunities. This paper shows how New York state implements community revitalization programs with the community supporting system. This research also shows how to organize and manage the community involvements in the planning process through the case study of the Black River Vision Plan/ City of Watertown that an author had participated in.

• Proceedings of the KAIS Fall Conference
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• 2012.05a
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• pp.119-121
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• 2012

현실적으로 선두 브랜드라고 할지라도 제대로 브랜드 관리가 되지 않으면 노후화를 막을 수 없고 언젠가는 실패한 브랜드가 되어 시장에서 퇴출될 수밖에 없다. '백설' 브랜드는 재활성화를 통하여 기존에 구축된 브랜드 자산을 부정하기 보다는 이를 토대로 브랜드 정책을 발전시켰다. 브랜드 재활성화의 핵심은 브랜드 참신성에 대한 성급한 시도보다는 브랜드 리뉴얼, 브랜드 리포지셔닝 그리고 브랜드 확장에 있어 브랜드가 쌓아 온 자산을 토대로 브랜드가 건강하게 나이를 먹을 수 있도록 체계적이고 단계적인 전략을 펼치는 것이다.

• Journal of the Speleological Society of Korea
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• no.92
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• pp.41-47
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• 2009

This study discussed revitalization of commercial caves. Transition of approach method about cave development is required. Each of the caves need differentiation strategy. In addition, the recognizing of the value of caves is required.

• Tunnel and Underground Space
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• v.26 no.2
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• pp.59-67
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• 2016

In this paper, we perform a numerical analysis to evaluate the potential of fault reactivation during gas production from hydrate bearing sediments and the moment magnitude of induced seismicity. For the numerical analysis, sequential coupling of TOUGH+Hydrate and FLAC3D was used and the change in effective stress and consequent geomechanical deformation including fault reactivation was simulated by assuming that Mohr-Coulomb shear resistance criterion is valid. From the test production simulation of 30 days, we showed that pore pressure reduction as well as effective stress change hardly induces the fault reactivation in the vicinity of a production well. We also investigated the influence of stress state conditions to a fault reactivation, and showed that normal fault stress regime, where vertical stress is relatively greater than horizontal, may have the largest potential for the reactivation. We tested one simulation that earthquake can be induced during gas production and calculated the moment magnitude of the seismicity. Our calculation presented that all the magnitudes from the calculation were negative values, which indicates that induced earthquakes can be grouped into micro-seismic and as small as hardly perceived by human beings. However, it should be noted that the current simulation was carried out using the highly simplified geometric model and assumptions such that the further simulations for a scheduled test production and commercial scale production considering complex geometric conditions may produce different results.

• Journal of the Economic Geographical Society of Korea
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• v.12 no.1
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• pp.38-55
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• 2009

Recently, attention has been drawn to the issue of local community revitalization. In the U.S., CDC(Community Development Corporation) has become a main vehicle for revitalizing dilapidated inner-city communities. Using the case of Philadelphia in the U.S., this paper investigates the way in which local community revitalization or downtown revitalization can be successfully achieved through the formation of social capital and public-private partnership. Futhermore, exploring the cases of West Philadelphia CDC and University City, this paper seeks to provide insight into the dynamics of successful community development. In order to examine the dynamics, this paper focuses on local governance in terms of both the reciprocal partnerships and the close networking among participating agents. The implications of the case studies of this research for the Korean context would be that the bottom-up approach starting from the local-scale community revitalization and local governance is very crucial and indispensable for the sustainable regional or national development.

• Korean Journal of Microbiology
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• v.37 no.2
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• pp.145-150
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• 2001

Reactivation of human cytomegalovirus (HCMV) from latency is often fatal to immunocompromised individuals. To understand the effect of HCMV on human monocytes where HCMV establishes latency, two human monocyte cell lines at different stages in differentiation, THP-1 and HL-60 were infected with HCMV. While the viability and morphology of HL-60 cells were not significantly affected by HCMV, the viability of THP-1 cells was dramatically decreased by HCMV infection. THP-1 cells infected with HCMV became aggregated and adhered to the surface of culture dishes, probably due to the increased expression of adherence molecules CD11b on the infected THP-1 cells. THP-1 cells established a latent HCMV infection were induced to differentiate by treatment with TPA and hydrocortisone. Recovery of infectious HCMV from the culture supernatant of differentiated THP-1 cells was dependent on the time of induction of differentiation after HCMV infection. Thus, in vitro model of reactivation of HCMV from latently infected monocytes was established.

• The Korean Journal of Pharmacology
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• v.22 no.2
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• pp.123-127
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• 1986

n-Butyrate (n-BT A) increased the rate and number of infectious units produced in the in vitro reactivation of latent herpes simplex virus. While the mechanism of action of n-BT A is obscure, a continuous presence of n-BT A is necessary for its inductive effect.

• Radiation Oncology Journal
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• v.29 no.1
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• pp.53-62
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• 2011

Radiation-induced liver disease (RILD) has been characterized as a veno-occlusive disease with anicteric elevation of alkaline phosphatase (ALP). However, some RILD patients present with elevated transaminase levels rather than with anicteric elevation of ALP, and these findings are common in the Asia-Pacific region where hepatitis B virus (HBV) infection is associated with 70~90% of hepatocelluar carcinoma (HCC) cases. In addition, the development of RILD is more common in patients with hepatitis B virus-related HCC. These findings indicate that susceptibility to RILD might be different in HBV carriers and non-carriers, and moreover, RILD in patients with HBV-related HCC might be associated with another unique pathogenesis such as HBV reactivation. However, HBV reactivation after hepatic irradiation has been reported in only a few studies. This study reports three cases of HBV reactivation alter hepatic tomotherapy for management of HCC.