• Title/Summary/Keyword: 장선

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Mouse Models of Atopic Dermatitis for Drug Discovery from Medicinal Plants (아토피 피부염 치료제 개발에 활용할 수 있는 마우스 모델에 대한 고찰)

  • Yun, Young-Gab;Hwang, Joo-Min;Kim, Hyung-Rul;Jang, Seon-Il
    • Herbal Formula Science
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    • v.15 no.1
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    • pp.145-161
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    • 2007
  • Atopic dermatitis (AD) is a chronic inflammatory skin disease associated with cutaneous hyperreactivity to environmental triggers. The clinical phenotype that characterizes AD is the product of interactions between susceptible genes, the environmental factors, defective skin barrier function, and immunologic responses. This review summarizes recent progress in our understanding of the immunopathophysiology of AD and the implications for mouse models of AD in drug discovery from medicinal plants.

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Consonant Inventories of the Better Cochlear Implant Children in Korea (말지각 능력이 우수한 인공와우 착용 아동들의 조음 특성 : 정밀전사 분석 방법을 중심으로)

  • Chang, Son-A;Kim, Soo-Jin;Shin, Ji-Young
    • MALSORI
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    • no.62
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    • pp.33-49
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    • 2007
  • The purpose of this study is 1) to investigate the phoneme inventories and phonological processes of cochlear implant(CI) children and 2) to describe their utterances using narrow phonetic transcription method. All ten subjects had more than 2 year-experience with CI and showed more than 85 % open-set sentence perception abilities. Average consonant accuracy was 81.36 % and it was improved up to 87.41% when distortion errors were not counted. They showed similar phonological processing patterns to HA or normal hearing children in some way as well as different phonological processing patterns from HA or normal hearing children. The prominent distortion error pattern was weakening of consonants. Every subject had his/her idiosyncratic error pattern that demanded his/her own individualized therapy program.

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Study on Antibody-enzyme Coupling and Enzyme Immunoassay Methods (효소-항체의 결합 및 효소면역측정 방법의 연구)

  • Jang Sean Il
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.3
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    • pp.874-879
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    • 2004
  • Alakaline phosphatase (ALP)- or horseradish peroxidase (HRP)-antibody conjugate was used frequently on the immunological detection methods such as enzyme-linked immunosobent assay (ELISA), immunobolt, immunohistochemistry. The classical enzyme-antibody coupling method by one-step (direction) injection of glutaraldehyde bring into being disadvantage such as low sensitivity of antigen detection because of homopolymers. This study was modified with the dialysis glutaraldehyde method to provide simple coupling through E-amino residues present in most protein. The dialysis glutaraldehyde coupling effects were better than the classical one-step glutaraldehyde injection in antigen detection of ELISA and immunobolt. Optimal dose of the dialysis glutaraldehyde solution was 0.10-0.25 %. This results suggest that the dialysis glutaraldehyde coupling method can readily applied to antigen detection of in vitro and in vivo.

Face Detection Using Color Information (색상 정보를 이용한 얼굴 영역 추출)

  • 장선아;유지상
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.25 no.6B
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    • pp.1012-1020
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    • 2000
  • In this paper, This paper presents a new algorithm which is used for detecting and extracting human masks from a color still image. The regions where each pixel has a value of skin-color were extracted from the Cb and Cr images, after the tone of the color image is converted to YCbCr from. A morphological filter is used to eliminate noise in the resulting image. By scanning it in horizontal and vertical ways under ways under threshold value, first candidate section is chosen. If it is not a face, secondary candidate section is taken and is divided into two candidate sections. The proposed algorithm is not affected by the variation of illuminations, because it uses only Cb and Cr components in YCbCr color format. Moreover, the face recognition was possible regardless of the degree of shifting face, changed shape, various sizes of the face, and the quality of image.

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Consonant Inventories of the Better Cochlear Implant Children in Korea (말지각 능력이 우수한 인공와우 착용 아동들의 조음 능력;음소의 정밀 전사)

  • Chang, Son-A;Kim, Su-Jin;Sin, Ji-Yeong
    • Proceedings of the KSPS conference
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    • 2007.05a
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    • pp.274-277
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    • 2007
  • The purpose of this study is 1) to describe the phoneme inventories of cochlear implant(CI) children and 2) to describe their utterances using narrow phonetic transcription method. All the subjects had more than 2 year-experience with CI and showed more than 87% open-set sentence perception abilities. Average consonant accuracy was 81.36% and it was improved up to 87.41% when distortion errors were not counted. They showed different error patterns from hearing aid users. The prominent error pattern was weakening of consonants.

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Perception of Adults' and Children's Stuttering in Korean Speech Language Pathologists and Laypeople (말더듬 성인과 아동에 대한 일반인 및 언어치료전문가 집단의 인식 연구)

  • Kim, Yu-Jung;Chang, Son-A;Shin, Moon-Ja
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.17 no.2
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    • pp.103-106
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    • 2006
  • Listeners' perception toward stuttering has been considered an important factor to the diagnosis and treatment of stuttering. This study intended to examine perceptual differences between speech language pathologists and laypeople toward children and adults with stuttering. A Total of 102 subjects were surveyed. speech language pathologists' perception was more stereotypical than that of laypeople. laypeople perceived adults and children with no significant differences but, clinicians viewed adults more stereotypically. speech language pathologists were not influenced by experiencer, but experienced laypeople perceived children more negatively although people who have stuttering family members showed a less stereotypically. item analysis revealed that both groups showed different perspectives between adults and children with stuttering.

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An Implementation of A Multi-Robot System Using Educational Mini-Robots (교육용 소형 로봇을 이용한 군집로봇 시스템 구현)

  • Yoo, Young-Dae;Jang, Seon-Ah;Yang, Jae-Gun;Park, Ji-Hyun;Bae, Jae-Hak J.
    • Proceedings of the Korean Information Science Society Conference
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    • 2008.06c
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    • pp.387-390
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    • 2008
  • 본 논문에서는 교구용 소형 로봇으로 구현한 군집로봇 시스템을 소개한다. 각 로봇에 내장된 블루투스 무선통신으로 군집로봇 네트워크를 구성하였다. 실험에 사용한 로봇은 $LEGO^{(R)}$ $MINDSTORMS^{(R)}$ NXT이다. 여러 로봇이 라인으로 표현한 대형 미로를 동시에 탐사하는 환경을 가정하였다. 이런 상황에서 각 로봇은 주어진 임무를 수행하면서 센서로 주변 환경 정보를 측정해서 대표 로봇에게 보낸다. 여기에 필요한 메시지 구조를 군집로봇에 적절하도록 설계하였다. 이렇게 군집로봇을 구현하고 실험한 결과, 그룹 대표로봇이 통신을 중계하는 방법으로 통신거리 제약을 해소할 수 있었다.

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Recording and Replay Service for a Grid-Based Hybrid Remote Experiment in Civil Engineering (그리드 기반의 토목공학 하이브리드 원격 실험의 리코딩 및 리플레이 서비스)

  • Jang, Sun;Lee, Jang-Ho
    • Proceedings of the Korean Information Science Society Conference
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    • 2007.06b
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    • pp.502-507
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    • 2007
  • 그리드 컴퓨팅 기술을 기반으로 한 원격 실험 환경 구축에 있어서 원격 실험만큼이나 실험결과 데이터를 저장하고 재연하는 것이 중요하게 대두되고 있다. 본 논문에서는 KOCED 프로젝트의 건설 연구 실험시설 중 하나인 실시간 하이브리드 다자유도 실험시설에 대한 프로토타입인 원격 하이브리드 실험에 대하여 나라다 브로커링 이라는 발간 및 구독 패러다임의 스트리밍 서버와 글로버스 툴킷에 기반 한 리코딩 및 리플레이 서비스를 통하여 실험결과 데이터를 저장하고 재연하는 시스템을 구축 하였다. 기존에 진행된 실험결과를 검색하여 볼 수 있게 함으로써 중복된 실험으로 인한 비용을 줄이고, 사용자가 원하는 데이터에 대한 토픽정보를 통하여 재연함으로써 실험결과 데이터의 효용성을 높일 수 있을 것으로 판단된다.

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Frequency Analysis on Parametric Resonance of Periodically Non-stationary Systems with Distributed Parameters (주기 비안정 연속계의 파라메터공진에 관한 주파수 해석)

  • Lee, Yong-Kwan;Chechurin, S.L.
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2004.11a
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    • pp.295-299
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    • 2004
  • 본 논문에서는 주기 비안정 연속계의 해석을 위한 주파수 방법이 제안된다. 비안정시스템의 안정화를 위한 기존의 주파수 해석법을 일부 수정하여 연속계를 포함한 비안정 시스템에 적합하도록 수정하였으며, 직류모터와 동기발전기로 구성되어 있는 전기-기계 시스템에 적용하여 유용성을 보였다. 복잡한 비안정 연속계의 문제를 각 요소별 주파수 응답을 분리하고 조합하는 작업들을 통하여 쉽게 풀 수 있음을 보였다. 모터-발전기로 구성되어있는 전기-기계 시스템에서 발전기의 상호유도인덕턴스의 시간에 따른 주기적 변화와 장선(long electrical line)의 부하가 시스템의 불안정성을 야기함을 보였다.

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