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Herbst Oral Appliance for Obstructive Sleep Apnea When Uvulopalatopharyngoplasty and Nasal CPAP Failed (구개수구개인두성형술 및 지속적 기도 양압 공급치료에 실패하였으나 Herbst 구강내 장치로 효과를 보인 폐쇄성 수면 무호흡 증후군 1예)

  • Moon, Hwa-Sik;Choi, Young-Mee;Kim, Myung-Lip;Park, Young-Hak;Kim, Young-Kyoon;Kim, Kwan-Hyoung;Song, Jeong-Sup;Park, Sung-Hak
    • Tuberculosis and Respiratory Diseases
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    • v.45 no.2
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    • pp.457-464
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    • 1998
  • This report describes a 5-month follow-up of the efficacy of Herbst oral appliance(OA) in a obstructive sleep apnea syndrome patient who has failed with uvulopalatopharyngoplasty(UPPP) and was unable to tolerate to subsequent nasal continuous positive airway pressure(CPAP) because of mouth air leak. The obstructive sleep apnea and daytime performance were markedly improved by regular home use of OA, and the patient still continues to use OA without complications. It is suggested that OA can be a successful alternative therapeutic modality in patients who are unable to tolerate to nasal CP AP, especially after UPPP.

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Selection of Mutant Silkworm with Oxidation-deficient Haemolymph for Insect Cell Culture (곤충세포 배지 개발을 위한 체액산화지연 돌연변이 누에계통 선발)

  • Choi, Ji-Young;Kim, Jong-Gill;Choi, Young-Cheol;Yoon, Hyung-Joo;Ahn, Mi-Young;Kim, Sam-Eun;Hwang, Seok-Jo
    • Journal of Sericultural and Entomological Science
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    • v.49 no.2
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    • pp.47-50
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    • 2007
  • Insect cell culture system has been demonstrated the effective means of producing medical and agricultural products. Furthermore, Fetal bovine serum (FBS) is in wide use in insect cell culture. Silkworm hemolymph was tested to develop as a substitute for FBS and was effective in insect cell growth. Hemolymph is oxidized and darkens visibly during the collection from silkworms due to the activity of tyrosinase in it. Toxic quinones are produced by the oxidation and consequently inhibit the cell growth. Heat treatment can be used to prevent the oxidation; however, the oxidation may occur during the collection of hemolymph before it is heat-treated. Hemolymphs collected from 257 different strains of silkworms were examined to select the slowly oxidized hemolymphs. Hemolymphs collected from mutant strains such as $Y_4$, TBO and $wE^b$ showed relatively slow color changes. Oxidation rates of the hemolymphs were measured by the absorbance change using a spectrophotometer. The absorbance of mutant hemolymph reached the saturation value at $20^{\circ}C$ in each 330 min ($Y_4$), 360 min (TBO) and 450 min ($wE^b$) min, whereas the total oxidation time of the wild-type (Baekokjam) hemolymph at the same temperature was 120 min. The cell growth in the medium supplemented with mutant species hemolmph was more effective that in the medium supplemented with Baekokjam species hemolymph.

Studies on the Rearing with Artificial Diet in the Silkworm, Bombyx mori L. -Electrophoretic Sepatarion of Esterase or Phosphatase along the Growth of Larvae- (가잠의 인공사료육에 관한 연구 -유충발육에 따른 Esterase 및 Phosphatase의 전기영동상-)

  • 김주읍
    • Journal of Sericultural and Entomological Science
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    • v.21 no.1
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    • pp.21-28
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    • 1979
  • The Electrophoretic separation in agarose gel on the esterase and acid phosphatase of blood, midgut and silk gland was carried out with 2 original variginal varieties and 7 F$_1$ hybrids. 1. The midgut of larvae fed on mulberry leaves showed one or two more esterase bands than that of larvae fed on artificial diet. 2. The midgut of C 15 larvae being excellently respondent to artificial diet showed one or two more esterase bands than that of larvae being bad respondent to artificial diet. 3. Electrophoretic separation of esterase bands appeared to be greatly different among newly hatched larvae, 1st and 2nd install larvae of F$_1$hybrids. However the difference among the silkworm varieties was not recognized. 4. According to the change in rearing temperature, the number of the active band of midgut esterase was varied. At the temperature of 28$^{\circ}C$ 5 active esterase bands were found. At temperature of 35$^{\circ}C$ 4 bands were noted at 3rd install and 6 or 7 bands at 4th instar. 5. No similar esterase bands conld be found among midgut, blood and silkgland. There are five esterase bands in the midgut, one in blood and three in silkgland. 6. There was rather small difference in acid phosphatase types of midgut and blood according to varieties and rearing temperature. No active band was shown in silkgland. In midgut, there was one acid phosphatase band at 3rd install, two at 4th instar and three at 5th instar. In blood, One active band at 3rd or 4th instar and three bands at 5th inatar were detected.

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Classification and Selection of the Breeding Materials in the Silkworm, Bombyx mori, by Multivariate Analysis 2. Combining Ability and its Pre-estimate for the Top Cross Set made from the Silkworm Parental Lines Selected by Principal Component Analysis. (다변량 해석법에 의한 누에 육종소재의 탐색 2. 주성분 SCORE에 의하여 분류된 주요잠품종간의 TOP 교잡에 의한 조합능력 검정과 예측)

  • 정도섭;이인전;이상몽;김삼은
    • Journal of Sericultural and Entomological Science
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    • v.32 no.1
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    • pp.17-30
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    • 1990
  • A 6${\times}$4 top-cross set was made from the ten silkworm parental lines selected by the first principal component scores. They were also analysed for the relationship between the combining ability and the first principal component score. The highest general combining ability effects were detected in the parental lines of Japanese, N39 and chinese, C46, for the most quantitative characters in the study. The first principal component score of factors related to silk productivity in the parents was significantly and positively correlated to the general combining ability of the twelve characters such as cocoon yield, cocoon weight, cocoon shell weight, cocoon shell percentage, duration of the 5th instar larvae, total larval period, length of a bave, weight of a have, non-breaking length of a bave, non-breaking weight of a have, raw silk percentage, and neatness. Similarity distance (D$^2$) was related to the specific combining ability of the characters such as cocoon yield, non-breaking length of a bave, non-breaking weight of a have, non-breaking ratio of a bave, raw silk percentage, neatness. From the results, it is possible to predict the general combining ability effects by the principal component scores for the 12 characters of the parents related to silk productivity.

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Induction and Characterization of Precocious Trimolting Silkworm, Bombyx mori (조숙 3면잠의 유발과 실용형질)

  • 이상덕;문재유
    • Journal of Sericultural and Entomological Science
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    • v.32 no.1
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    • pp.31-37
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    • 1990
  • For fine-denier cocoon filament production, the precocious trimolting silkworms were induced by the treatments with both the imidazole compound "KK-42" hating anti-juvenile hormone activity and high temperature, and their growth, dietary efficiency, cocoon and cocoon filament qualities were compared with those of normal tetramolters as control. 1. The percentage of precocious trimolters was higher in the application of KK-42 than the treatment of high temperature. The effective concentration of KK-42 was 10$\mu\textrm{g}$/1arva. The high temperature treatment for 48 hour was more effective than 36 hour treatment, and silkworm larvae fed on mulberry leaves were more sensitive than artificial diet to induce trimolters. 2. The larval duration of the trimolters induced by KK-42 was 5.17 day shorter than that of normal tetramolters in mulberry leaves rearing, and the increasing pattern of body weight in the 4th inster larvae of trimotlers was similar to the 5th instar larvae of normal tetramolters. 3. The qualities such as cocoon weight, cocoon layer weight and cocoon layer ratio of precocious trimolter induced by KK-42 were much lower those of normal tetramolters: the cocoon weight and cocoon layer ratio were 0.78g, 14.2cg and 18.4% in mulberry leaves rearing, and 0.86 cg, 10.3cg and 12.3% in artificial diet rearing, respectively. 4. The size of cocoon and cocoon filament was smaller in the precocious trimolter, both KK-42 and high temperature, as compared with that of the normal tetramolters. 5. The efficiency of cocoon layer production of the precocious trimolters by the KK-42 was lower than that of the normal tetramolters: amount of the cocoon layer production per 1g of dry mulberry leaves ingested was 7.97cg in the precocious trimotors, while 9.20cg in the normal tetramolters.

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A Study on the Development of Person-Based Class Materials in Subject (<수학과제 탐구> 과목의 인물 중심 수업 자료 개발 관련 연구)

  • Lee, Dong Gun
    • Communications of Mathematical Education
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    • v.35 no.4
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    • pp.475-504
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    • 2021
  • This study is a study that developed class materials that can be applied directly to classes by field teachers in consideration of ' research on the development is valuable as a field support study.', 'In material development, organizing data centering on the knowledge composition and inquiry activities of characters related to the mathematics concept can help develop class materials', and 'The fact that the development of subject data for has been insufficient'. To this end, this study went through the procedure of 'establishing a data development plan, data development, verifying field teachers on development data, verifying subject experts on development data, and developing final data reflecting verification opinions.' Therefore, based on the 1st 50 minutes reflecting the task exploration model, it was possible to develop class materials for the 3rd time. In this study, development data were presented with a 17-week curriculum plan, a class guidance plan that presents teacher-student interaction, and a task development form that students fill out and submit in class. This study was developed with the developed data in mind to be applied to actual classes. Therefore, a follow-up study is needed to apply the developed data to actual classes and analyze the results.

A study on the performance verification of an around-view sonar and an excavation depth measurement sonar application to ROV for track-based heavy works (트랙기반 중작업용 ROV에 적용 가능한 어라운드 뷰 소나 및 굴착깊이 측정 소나 성능 검증에 관한 연구)

  • Son, Ki-Jun;Park, Dong-Jin;Kim, Min-Jae;Oh, Young-Suk;Park, Seung-Soo
    • The Journal of the Acoustical Society of Korea
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    • v.38 no.2
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    • pp.161-167
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    • 2019
  • In this paper, the performance verification of an around-view sonar and an excavation depth measuring sonar applicable to track-based ROVs (Remotely Operated underwater Vehicles) for heavy duty work is studied. For the performance verification, an experiment is carried out in a water tank and at sea by attaching the around-view sonar and the excavation depth measuring sonar for a heavy work ROV. In the case of the around-view sonar, image sonars are mounted on ROV in four directions (front, back, left and right) and in the case of the excavation depth measuring sonar, the same kind of MBES (Multi Beam Echo Sounder) is mounted on the front of the ROV. The result of an operation test of the ROV equipped with these sonars shows that the sonar systems are rarely affected by high turbidity due to sedimentation during the operation. In the case of the around-view sonar, it is possible to see rock formation, gravel and sandbank 30 m ahead of the ROV. It is confirmed that the excavation depth can be measured after the ROV has performed the excavation. This experiment demonstrates that the ROV can improve the efficiency of the work by utilizing the around-view sonar and the excavation depth measuring sonar.

Observation on the Seabed around Simheungteak Seamount near Dokdo and using Mini-ROV (소형 ROV를 활용한 독도 및 심흥택해산 해저면 탐사)

  • MIN, WON-GI;RHO, HYUN SOO;KIM, CHANG HWAN;PARK, CHAN HONG;KIM, DONGSUNG
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.24 no.1
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    • pp.18-29
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    • 2019
  • ROV surveys were conducted using 500 meter mini class ROV with HD video camera, 2 LED lights, a simple manipulator and 8 thrusters near the Dokdo and Simheungtaek seamount. Total six dives have been conducted using the ROV "V8 SII" from Sweden and ROV's support ship, "KOSAL V" at 4 stations between 45 and 370 meters with diving time ranged from 30 to 120 minutes. Dense communities of sea anemone (Actinostolidae sp.) and ophiuroids (Ophiuridae sp.) on the surface of rocky bottom and snow crab on the soft bottom with muddy-sand were observed at northwestern part of Simheungtaek seamount. We obtained the following results 1) habitats information for snow crab, one of the major fisheries resources, and deep-sea fauna, 2) observation on the specific topography and sediment conditions, 3) observation of the seabed surface covered with the discarded fishing gears. This study represents the first report of in situ visual observation of deep-sea organisms and their habitats near the Dokdo slopes and flat top of the Simheungtaek seamount in the East Sea. These results indicated that immediate oceanographic survey using the mini class ROV is available in the East Sea.

A Study to Improve the Usability of the Smart Sleeping Mask based IoT (사물인터넷 기반 수면안대의 사용감 향상을 위한 연구)

  • Kwak, Jin-Young;Yang, Yeon-Ju;Lim, Jea-Kwan;Yoon, Sang-Cheol;Ahn, Taek-Won
    • Journal of Internet of Things and Convergence
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    • v.8 no.6
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    • pp.27-33
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    • 2022
  • Sleep is an essential factor for living a healthy life, but most modern people complain of poor sleep. For these people, as the need for a means to simply evaluate and manage the quality of sleep increases, devices that can check the sleep state at home without monitoring by an examiner are being developed. The smart sleep mask, which is the subject of this usability test, provides bio-signal monitoring while sleeping so that you can conveniently measure and manage your sleep state for yourself. The purpose of this study is to evaluate the usability and safety of the smart sleep mask, to find and prevent potential factors related to errors in use that may occur, and to develop the comfort and safety of this product. As a result of the formative evaluation of the sleep mask prototype, it was reported that it was difficult to turn on the power and check the results, and that the sleep mask was not comfortable to wear. Different opinions were presented on the size and weight of the sleeping mask by people in different age groups.

Effect of storage temperature, period, and sawdust addition on the biochemical methane potential of cattle manure (우분의 저장온도, 저장기간, 톱밥의 혼합에 따른 메탄잠재량 변화)

  • Im, Seongwon;Kim, Sangmi;Kim, Hyu hyoung;Kim, Dong-Hoon
    • Journal of the Korea Organic Resources Recycling Association
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    • v.29 no.1
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    • pp.29-36
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    • 2021
  • In spite of the highest energy potential among all domestic organic solid wastes. the research on biogas production from cattle manure is limited. In particular, effects of organic content degradation and sawdust addition during storage on biomethane potential have never been investigated. In the present work, we investigated the change of organic content during storage of cattle manure under different temperatures (20℃ and 30℃), and its impact on biomethane potential and odor emissions. 90 days of investigation results showed that 10% of organics in terms of VS and COD were degraded at 20℃ during storage, while 30% were degraded at 30℃. This result impacted on biomethane potential, while 10-13% and 24% reduction were observed from beef and dairy cattle manure, respectively. The temperature also affected on CH4 and odor emissions during storage by 3.3-3.8 times and 29 times. The effect of sawdust on lowering down biomethane potential was found to be substantial, reducing 61-75% compared to the control.