• Title/Summary/Keyword: 잔류조직

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Antimicrobial Effect of Grapefruit Seed Extract on Preservation for Carrot and Spinach (당근과 시금치 저장에 있어서 자몽종자추출물의 항균효과)

  • Kim Mi-Kyung;Park Mi-Suk;Choi Sun-Uk;Park Hae-Ryong;Hwang Yong-Il
    • Journal of Life Science
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    • v.15 no.1 s.68
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    • pp.66-70
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    • 2005
  • In order to preserve the freshness of vegetables and to reduce the rate of decay, grapefruit seed extract (GFSE), a natural microorganism growth inhibiting agent, was applied during the preservation process of heat treated carrot and spinach. To investigate synergic effect of heat and GFSE treatment, carrots and spinaches were treated with or without 10 ppm of GFSE at $70^{\circ}C$. Surface color, texture and microbial counts of the samples were measured during storage at $4^{\circ}C$. GFSE showed an effective inhibitory activity against aerobic bacteria and yeast which might be involved in the decay of vegetables. Heat treatment at 2 min at $70^{\circ}C$ could also well preserve the color and texture of the vegetables. From the results, optimal concentrations of GFSE were 10 ppm and 50 ppm with heat treatment of 2 min $70^{\circ}C$ for the growth inhibitory effect to aerobic bacteria and yeast and preservation of color and texture.

Granulite-facies metamorphism and P-T evolutionary path of cordierite gneisses in the Cheongpyeong-Yangpyeong area (청평-양평 지역에 분포하는 근청석 편마암의 백립암상 변성작용과 P-T 진화 경로)

  • 조윤호;조문섭;이승렬
    • The Journal of the Petrological Society of Korea
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    • v.5 no.1
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    • pp.52-65
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    • 1996
  • Precambrian metamorphic rocks of the Cheongpyeong-Yangpyeong area, central Gyeonggi massif, comprise gneiss, schist, quartzite and amphibolite. Mineral, assemblages of pelitic gneisses are characterized by biotite + cordierite + garnet + sillimanite + K-feldspar + plagioclase + quartz together with minor muscovite, spinel and corundum, and represent the granulite facies metamorphism. In particular, kyanite occurs as fine-grained relict phase inside plagioclase of three gneiss samples. Metamorphic conditions are estimated from garnet-biotite and garnet-cordierite geothermometers in conjunction with garnet-$Al_2SiO_5$-quartz-plagioclase (GASP) and garnet-rutile-$Al_2SiO_5$-ilmenite (GRAIL) geobarometers. They are 700-$850^{\circ}C$ and 3.2-8.3 kbar, and 580-$690^{\circ}C$ and 2.1-3.2 kbar, respectively, when the core and rim compositions of garnet are use. Garnet of the GASP assemblage increases rimward in the Fe and Mn contents but decreases in the Mg content, whereas its Ca content does not vary significantly. Together with the occurrence of relict kyanite and the result of P-T estimates, compositional zoning patterns of garnet indicate a clockwise P-T history. Moreover, the preservation of high-pressure minerals such as kyanite in plagiocalse, even after the medium-pressure granulite facies metamorphis, suggests a rapid change in P-T conditions.

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Anisotropy of Magnetic Susceptibility (AMS) of Granitic Rocks in the Eastern Region of the Yangsan Fault (양산단층 동편 화강암질암의 대자율 이방성(AMS))

  • Cho, Hyeong-Seong;Son, Moon;Kim, In-Soo
    • Economic and Environmental Geology
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    • v.40 no.2 s.183
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    • pp.171-189
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    • 2007
  • A study of anisotropy of magnetic susceptibility (AMS) was undertaken on Cretaceous granitic, volcanic and sedimentary rocks in the eastern region of the Yangsan fault, southeast Korea. A total of 542 independently oriented core samples collected form 77 sites were studied. The main magnetic mineral in granitic rocks is magnetite according to the magnitude of bulk susceptibility, high-temperature susceptibility variation and isothermal remanent magnetization. Both of magnetic lineation and foliation with NE-SW trends are revealed in the granitic rocks, while volcanic rocks show scattered directions and sedimentary rocks show only load foliation parallel to the bedding planes. The following evidences read to the conclusion that both magnetic fabrics in the granitic rocks have been obtained by a tectonic stress before full solidification of the magma: (i) A fully hardened granitic rocks would get hardly any fabric, (ii) Difference of the magnetic fabric trends with those of the geological structures in the granitic rocks themselves formed by brittle deformation after solidification (e.g. patterns of small-faults and joints), (iii) Kinking of biotite and undulose extinction in quartz observed under the polarizing microscope, (iv) Discordance of magnetic fabrics in the granitic rocks with those in the surrounding rocks. The NE-SW trend of the magnetic foliations suggests a NW-SE compressive stress of nearly contemporaneous with the emplacement of the granitic rocks. The compression should have caused a sinistral strike-slip movement of the Yangsan Fault considering the trend of the latter. As the age of the granitic rocks in the study area is reported to be around $60\sim70$ Ma, it is concluded that the Yangsan fault did the sinistral strike-slip movement during this time (L. Cretaceous Maastrichtian - Cenozoic Paleocene).

Geoacoustic Model of Surface Sediments in the East of Geoje Island, the South Sea of Korea (거제도 동쪽 해역 표층 퇴적물의 지음향모델)

  • KIM, GIL YOUNG;KIM, DAE CHOUL;SHIN, BO KYOUNG;SEO, YOYUNG KYO;LEE, GWANG HOON
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.10 no.2
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    • pp.129-138
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    • 2005
  • Sediment texture, physical (porosity, water content, bulk density, grain density, and shear strength), and geoacoustic properties (compressional wave velocity and attenuation) were measured on eighteen core samples collected from the shelf off eastern Geoje Island, the South Sea of Korea. Based on these properties, the study area is divided into three different sub-areas: (1) Area I affected directly by the Nakdong River discharge; (2) Area II covered by the southern branch of the Nakdong River discharge; and (3) Area III dominated by relict sediment. Mean grain size, velocity, and bulk density decrease from Area $I(7.4\Phi,\;1528m/s,\;1.6g/cm^3,\;respectively)$ to Area $II(8.1\Phi,\;1485m/s,\;and\;1.5g/cm^3)$, and then increase rather rapidly in Area $III(1.4\Phi,\;1664m/s,\;and\;2.2g/cm^3)$. Porosity, on the other hand, exhibits an opposite trend, increasing from Area $I(64.5\%)$ to Area$II(73.9\%)$ and then decreasing significantly in Area $III(32.9\%)$ From the results measured and calculated, we suggest a specified geoacoustic model in the study area.

Physical Properties of Sandy Sediment in the Southeastern Coast of Korea (한국 남동해역 사질퇴적물의 물리적 성질)

  • KIM Gil-Young;KIM Dae-Choul;PARK Soo-Chul;YOO Dong-Geun;CHOI Jin-Hyuk;KIM Jeong-Chang
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.29 no.5
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    • pp.663-676
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    • 1996
  • Physical properties and textural parameters of thirty-five piston tore samples recovered from the southeastern coast of Korea (Korea Strait), were investigated using the autopycnometer. The physical properties (porosity, water content, wet bulk density, dry bulk density, gram density, and void ratio) were measured at rather uniform intervals along each core. Sediment texture (grain size, sand, silt, and clay contents) was also measured at the same subbottom depth. The measured and calculated results are; mean grain size $0.57\~8.09\phi(average:3.67\phi)$, porosity $26\~81\%\;(average:\;55\%)$, water content $16.7\~61.4\%(average:\;31.6\%)$, wet bulk density $1.37\~2.18g/cm^3\;(average:\;1.85g/cm^3)$, dry bulk density $2.55\~3.11g/cm^3\;(average:\;2.35g/cm^3)$, grain density $2.40\~3.10g/cm^3\;(average:\;2.85g/cm^3)$, and void ratio $0.56\~2.54$ (average: 0.94). The sediment texture generally coincides well with the bathymetry indicating the influence of Pleistocene-Holocene sea level changes. Also the contours of physical properties are closely related to the sediment texture. Fluctuation of physical properties are similar to the textural variation. It seems that sediment texture is a significant factor in determining physical property in this study area.

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Pharmacokinetics and Bio-distribution of New Gd-complexes of DTPA-bis (amide) (L3) in a Rat Model (쥐를 이용한 새로운 가돌리늄 조영제 Gd-DTPA-bis(amide)(L3)의 약동학 및 생체내 분포 특성에 대한 연구)

  • Yan, Gen;Wu, Renhua;Chang, Yongmin;Kang, Duksik
    • Investigative Magnetic Resonance Imaging
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    • v.17 no.4
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    • pp.259-266
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    • 2013
  • Purpose : To investigate the blood pharmacokinetics and bio-distribution of DTPA-bis-amide (L3) Gd(III) complexes. Materials and Methods: The pharmacokinetics and bio-distribution of Gd $(L3)(H_2O){\cdot}nH_2O$ were investigated in Sprague-Dawley rats after intravenous administration at a dose of 0.1 mmol Gd/kg. The Gd content in the blood, various tissues, and organs was determined by ICP-AES. Blood pharmacokinetic parameters were calculated using a two-compartment model. Results: The half-lives of ${\alpha}$ phase and ${\beta}$ phase Gd $(L3)(H_2O){\cdot}nH_2O$ were $2.286{\pm}0.11$ min and $146.1{\pm}7.5$ min, respectively. The bio-distribution properties reveal that the complex is mainly excreted by the renal pathway, and possibly excreted by the hepatobiliary route. The concentration ratio of Gd (III) was significantly higher in the liver and spleen than in other organs, and small amounts of Gd (III) ion were detected in the blood or other tissues of rats only after 7 days of intravenous administration. Conclusion: The MRI contrast agent Gd $(L3)(H_2O){\cdot}nH_2O$ provides prolonged blood pool retention in the circulation and then clears rapidly with minimal accumulation of Gd(III) ions. The synthesis of gadolinium complexes with well-balanced lipophilicity and hydrophilicity shows promise for their further development as blood pool MRI contrast agents.

Muscle tissue Distribution Level of Ampicillin in Olive flounder(Paralichthys olivaceus), Rockfish(Sebastes schlegeli), and Red sea bream(Pagrus major) following oral administration (Ampicillin의 경구투여에 따른 양식 어류(넙치, 조피볼락, 참돔)의 근육조직내 잔류량의 변화)

  • Cho Yoon-Hee;Jung Won-Chul;Shin Yong-Woon;Kim Kyoung-Won;Ha Ji-Young;Heo Sung-Hyek;Kim Eui-Gyung;Chung Hee-Sik;Kang Seok-Joong;Choi Yu-Jeong;Kim Suk;Lee Hu-Jang
    • Journal of Veterinary Clinics
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    • v.23 no.2
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    • pp.164-168
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    • 2006
  • The residue depletion of ampicillin was investigated in the olive flounder (Paralichthys olivaceus), rockfish (Sebastes schlegeli), and red sea bream (Pagrus major) after 5 days treatment with medicated feed at a dose of 100 mg/kg bw/day. Fishes were sampled for muscle on 1st, 2nd, 3rd, and 4th day after treatment. Ampicillin concentrations were determined by high performance liquid chromatography after SPE column extraction. The recovery rates of ampicillin in muscle samples ranged 94-98% and 83-88% for the concentration of 0.05 mg/kg and 0.1 mg/kg, respectively. Ampicillin concentrations detected on 1st day after treatment were 0.143, 0.138, and 0.187 mg/kg in the muscle of olive flounder, rockfish, and red sea bream, respectively. After a withdrawal of 3 days, muscle concentrations were 0.016, 0.012, and 0.021 mg/kg in the olive flounder, rockfish, and red sea bream, respectively. Ampicillin was not detectable in muscle samples on 4 days following withdrawal of the medicated feed. From results of the present study, a withdrawal period of ampicillin is proposed on 5 days after 5 days treatment with medicated feed at a dose of 100 mg/kg bw/day to avoid the presence of excessive residues of the edible muscles of olive flounder, rockfish, and red sea bream.

Comparison of detecting methods and the relationship between tissue and blood for enrofloxacin and metabolic ciprofloxacin residues in broiler chickens (육계에서 조직과 혈액의 enrofloxacin 및 대사성 ciprofloxacin 잔류 상관관계 조사 및 검사방법간의 비교)

  • Sung, Myung-Suk;Kim, Mi-Suk;Seo, Hee-Jin;Bae, Dong-Rok;Hwang, Ji-Young;Kim, Soon-Tae;Cho, Jong-Suk;Park, Hong-Je;Hong, Sung-Hee;Kim, Gyung-Dong;Jang, Seong-Jun;Yun, Mun-Jo
    • Korean Journal of Veterinary Service
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    • v.36 no.4
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    • pp.311-320
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    • 2013
  • The purpose of this study was to evaluate detecting methods and the relationship between tissues and blood for enrofloxacin and metabolic ciprofloxacin residues in broiler chickens. Two groups of broiler chickens were administrated via the drinking water with $50{\mu}g/mL$ and $100{\mu}g/mL$ of enrofloxacin for 5 days, respectively. The concentration of enrofloxacin and metabolic ciprofloxacin in tissues (muscle and kidney) and blood were measured during administration period (for 5 days) and withdrawal period (for 12 days) by high performance liquid chromatography (HPLC) method. Also, all samples were conducted for screening of residues by microbial method using E. coli for quinolone detection and immuno-chromatography method using Smart kit. The relationship between tissues (muscle and kidney) and blood for enrofloxacin and metabolic ciprofloxacin residues in broiler chickens was followed : The levels of enrofloxacin and metabolic ciprofloxacin residues in muscle and kidney were higher 2.9~3.2 folds, 3.6~3.8 folds more than the residues levels in blood, respectively. These results support we can predict the residues in muscle and kidney from the residues in blood. In comparison of detecting methods for antibiotic residues, microbial method using E. coli for quinolone detection and immuno-chromatography method using Smart kit could detect positive reaction at similar or lower concentration than violative concentration of enrofloxacin and metabolic ciprofloxacin in chicken tissues. These results support what two screening methods are useful for screening of quinolone detection in chickens.

Usefulness of Tc-99m MIBI Scan in the Postoperative Follow Up Of Well-Differentiated Thyroid Cancer (분화된 갑상선암의 수술후 경과 관찰에서 Tc-99m MIBI 스캔과 다른 추적 지표들의 유용성 비교)

  • You, Kye-Hwa;Song, Jae-Soon;Shinn, Joon-Jae;Lee, Hyun-Kyung;Cha, Wang-Ki;Kim, Do-Min;Kim, Eun-Sil;Kim, Chong-Soon
    • The Korean Journal of Nuclear Medicine
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    • v.31 no.3
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    • pp.356-364
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    • 1997
  • To evaluate the clinical utility of Tc-99m MIBI scan in the detection of residual thyroid tissue or metastatic lesion in postoperative thyroid cancer patients, we compared Tc-99m MIBI scan with I-131 diagnostic and therapeutic scan in 30 postoperative well-differentiated thyroid cancer patients. Thyroglobulin levels of both on and off thyroid hormone medication and antithyroglobulin antibody were tested [Tg(on), Tg(off)]. Positive rates for I-131 diagnostic and Tc-99m MIBI scan were 81% and 68% respectively. Concordance between I-131 diagnostic and Tc-99m MIBI scan was observed in 15 cases; 12 positive and 3 negative respectively. Among the 6 cases with negative I-131 diagnostic scan and positive Tc-99m MIBI scan, 4 were Positive in the therapeutic I-131 scan We concluded that Tc-99m MIBI scan maybe a useful complementary modality to the currently established method of I-131 scan and serum thyroglobulin level in the detection of recurrent or metastatic thyroid cancer, especially in the case of negative I-131 diagnostic scan.

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구분린 완전결정을 이용한 중성자 단색기의 원리

  • ;;;P. Mikula
    • Proceedings of the Korea Crystallographic Association Conference
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    • 2003.05a
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    • pp.22-22
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    • 2003
  • 원자로에서 핵분열에 의해 생성된 고에너지 중성자는 감속재를 통해 열평형에 의해 에너지가 낮춰져 통계적 분포, 즉 Maxwell-Boltzman 운동에 따른 에너지 스펙트림을 갖게 된다. 중성자 산란장치는 통상 단색빔을 이용하므로 단색기(monochiomator)를 통해 이 분포에서 특정 파장의 중성자빔을 인출, 즉 단색화한다. 이때 단색기는 각각의 중성자 산란장치에 사용할 수 있는 특정 파장의 중성자빔을 인출하면서도, 파장의 퍼짐을 적절하게 조절하여 높은 중성자속(neutron flux)을 가지며 분해능도 또한 좋아야 한다. 전통적으로 많이 사용하는 단색화 방법은 결정의 내부결함을 유도하여 만든 모자익(mosaic) 결정을 이용하는 것이다. 이 방법은 특정 파장을 얻으면서도 좋은 분해능과 높은 중성자속을 갖는 모자익 결정을 만들기가 어렵고, 한번 결정된 단색기의 특성을 바꿀 수 없는 단점이 있다. 1980년대부터 몇몇 그룹이 거의 완전하게 성장된 단결정 슬랩을 미세하게 구부려서 탄성변형을 주어 effective 모자익 구조를 발생시킨 '구부린 완전결정(bent perfect crystal, BPC)' 단색기를 개발하여 특정 목적에 활용하는 시도를 하였다. BPC 단색기는 단색화된 중성자빔을 집속(focusing)할 수 있으며, 결정의 구부림 정도를 조절하고 배치 기하를 바꿈으로써 다양한 특성을 갖는 단색빔을 얻을 수 있는 장점이 있다. 이렇게 단색기의 기하학적 변수를 조절함으로써 회절빔의 집속도와 분해능을 조절할 수 있어서 잔류응력 측정이나 단결정 회절 및 집합조직 측정장치 등에 적용할 수 있다. 본 연구에서는 BPC 단색기의 원리와 여러 배치기하에 따른 빔의 특성을 소개하고자 한다.빔이 시료와 상호 작용하는 면적과 상호작용하지 않을 때의 빔을 회절모드에서 faraday cup으로 측정한 빔전류로 부터 계산하였다. Gibbsite에 대한 전자빔 조사 시 1분 이내에 급격한 Hydroxyl Ion(OH-)의 이탈로 인해 Cibbsite의 구조는 거시적 비정질화가 되며 시간증가에 따라 χ-alumina → ν-alumina → σ-alumina or δ-alumina의 순으로 상전이를 겪는다. 전자빔 조사 시 관찰된 회절자료의 가시적 변화를 통해 illumination angle 1.25mrad(Dose rate : 334 × 10³ e/sup -//sec·n㎡)일 경우 약 3초 이내에 비정질화가 시작됨을 알 수 있었고 이는 약 1 × 10/sup 6/ e/sup -//sec·n㎡ 의 전자선량에 해당되며 이를 기준으로 각각의 illumination angle에 대한 임계전자선량을 평가할 수 있었다. 실질적으로 Cibbsite와 같은 무기수화물의 직접가열실험 시 전자빔 조사에 의해 야기되는 상전이 영향을 배제하고 실험을 수행하려면 illumination angle 0.2mrad (Dose rate : 8000 e/sup -//sec·n㎡)이하로 관찰하고 기록되어야 함을 본 자료로부터 알 수 있었다.운동횟수에 의한 영향으로써 운동시간을 1일 6시간으로 설정하여, 운동횟수를 결정하기 위하여 오전, 오후에 각 3시간씩 운동시키는 방법과 오전부터 6시간동안 운동시키는 두 방법을 이용하여 품질을 비교하였다. 각 조건에 따라 운동시킨 참돔의 수분함량을 나타낸 것으로, 2회(오전 3시간, 오후 3시간)에 나누어서 운동시키기 위한 육의 수분함량은 73.37±2.02%를 나타냈으며, 1회(6시간 운

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