• Title/Summary/Keyword: 임상 결과 예측

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The Significance of $^{99m}Technetium$ Dimercaptosuccinic Acid(DMSA) Scan as a Substitute for Voiding Cystourethrography(VCUG) in Evaluating Children with first Febrile Urinary Tract Infection (생애 첫 발열성 요로 감염 환아에 대한 평가에서 배뇨성 방광 요도 조영술을 대체하기 위한 검사로서 $^{99m}technetium$ dimercaptosuccinic acid(DMSA) scan의 의의)

  • Han, Seung-Beom;Ko, Yong-Min;Lee, Sue-Young;Jeong, Dae-Chul;Kang, Jin-Han;Lee, Kyung-Yeon;Uhm, Mee-Ryung;Kim, Woong-Heum;Kim, Jung-Sue
    • Childhood Kidney Diseases
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    • v.11 no.2
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    • pp.220-228
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    • 2007
  • Purpose : We studied the value of clinical signs, laboratory findings and $^{99m}technetium$ dime-rcaptosuccinic acid(DMSA) scan in predicting the presence of vesicoureteral reflux(VUR) in children with first febrile urinary tract infection(UTI). Methods : A retrospective analysis of 84 hospitalized children with first febrile UTI was performed. They underwent DMSA scan and voiding cystourethrography(VCUG) during the acute phase, and were divided into three groups according to the results of the VCUG: absence of VUR, mild(grade I-II) and severe VUR(grade III-V). We studied the relation of VUR to age, gender, fever duration, causative organism, white blood cell count, serum C-reactive protein and result of DMSA scan. Results : Among 84 patients, 6 had mild and 17 had severe VUR. Thirty-eight had abnormal DMSA scan. results Patients with VUR were older than those without VUR(P<0.01). There was a lower probability of infection with Escherichia coli in patients with severe VUR than in those with mild and absent VUR(P<0.01). An abnormal DMSA scan correlated with the presence and severity of VUR(P<0.05). Severe VUR was present in 10.9% of patients with normal DMSA scan. The sensitivity, specificity, positive and negative predictive values of the DMSA scan in predicting the presence of VUR were 69.6%, 63.9%, 42.1%, and 84.8%, respectively. Conclusion : An abnormal DMSA scan correlated to the presence and severity of VUR, but the sensitivity, specificity and positive predictive value of the DMSA scan were low. There-fore, patient with an abnormal DMSA scan requires a VCUG. In order to prevent missing the 10.9% of patients with severe VUR but normal DMSA scans, a VCUG should be performed in patient with normal DMSA scan.

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Effects on Dental Infection Control Practice Level of Some Dental Hygiene Students (일부 치위생과 학생들의 치과 감염관리 실천도에 미치는 영향)

  • Seok-Yeon Cheon
    • Journal of the Health Care and Life Science
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    • v.11 no.1
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    • pp.165-172
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    • 2023
  • This study involved 220 dental hygiene students who had experience in field clinical practice. It was carried out to grasp the awareness and practice of dental infection control and to use it as basic data for dental infection control practice. As a result of examining the awareness of dental infection control, the average score was 4.58 points, and the average infection control practice was 4.50 points. As a result of identifying differences between infection control awareness and practice, there were statistically significant differences in all domains. As a result of investigating the effect on infection prevention practices, the grade level, the experience of infection during practice, whether infection control guidelines are provided in the laboratory, awareness of handwashing areas, and wearing personal protective equipment were found to be significant predictors.

Impacts of Diastolic Function on Clinical Outcomes in Young Patients with Acute Myocardial Infarction (젊은 급성 심근경색증 환자에서 좌심실 이완 기능 및 충만압이 관상동맥중재술 후 임상 경과에 미치는 영향)

  • Cho, Eun Young;Jeong, Myung Ho;Yoon, Hyun Ju;Kim, Yong Cheol;Sohn, Seok-Joon;Kim, Min Chul;Sim, Doo Sun;Hong, Young Joon;Kim, Ju Han;Ahn, Youngkeun;Cho, Jae Young;Kim, Kye Hun;Park, Jong Chun
    • The Korean Journal of Medicine
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    • v.93 no.6
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    • pp.538-547
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    • 2018
  • Background/Aims: The impact of left ventricular (LV) diastolic function and filling pressure on clinical outcomes in young patients with acute myocardial infarction (AMI) has been poorly studied. Therefore, the aim of this study was to investigate the impact of LV diastolic function and LV filling pressure on major adverse cardiac events (MACEs) in young patients with AMI. Methods: A total of 200 young patients (males < 45 year, females < 55 year) with AMI were divided into two groups according to the diastolic function; normal (n = 46, $39.5{\pm}5.3$ years) versus abnormal (n = 154, $43.5{\pm}5.1$ years). Results: Despite regional wall motion abnormalities, normal LV diastolic function was not uncommon in young AMI patients (23.0%). During the 40 months of clinical follow-up, MACEs developed in 26 patients (13.0%); 14 re-percutaneous coronary intervention (7.0%), 8 recurrent MI (4.0%), and 4 deaths (2.0%). MACEs did not differ between the normal and abnormal diastolic function group (13.6% vs. 10.9%, p = 0.810), but MACEs were significantly higher in the high LV filling pressure group than the normal LV filling pressure group (36.8% vs. 10.5%, p < 0.001). On multivariate analysis, high LV filling pressure was an independent predictor of MACEs (hazard ratio 3.022, 95% confidence interval 1.200-7.612, p = 0.019). Conclusions: This study suggested that measurement of the LV filling pressure (E/e' ratio) would be useful in the risk stratification of young patients with AMI. However, it would be necessary to monitor this category of patient more carefully.

Surgical Decision for Elderly Spine Deformity Patient (노인 척추 변형 환자의 수술적 결정)

  • Kim, Yong-Chan;Juh, Hyung-Suk;Lee, Keunho
    • Journal of the Korean Orthopaedic Association
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    • v.54 no.1
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    • pp.1-8
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    • 2019
  • Globally, the elderly population is increasing rapidly, which means that the number of deformity correction operations for elderly spine deformity patient has increased. On the other hand, for aged patients with deformity correction operation, preoperative considerations to reduce the complications and predict a good clinical outcome are not completely understood. First, medical comorbidity needs to be evaluated preoperatively with the Cumulative Illness Rating Scale for Geriatrics or the Charlson Comorbidity Index scores. Medical comorbidities are associated with the postoperative complication rate. Managing these comorbidities preoperatively decreases the complications after a spine deformity correction operation. Second, bone densitometry need to be checked for osteoporosis. Many surgical techniques have been introduced to prevent the complications associated with posterior instrumentation for osteoporosis patients. The preoperative use of an osteogenesis inducing agent - teriparatide was also reported to reduce the complication rate. Third, total body sagittal alignment need to be considered. Many elderly spine deformity patients accompanied degenerative changes and deformities at their lower extremities. In addition, a compensation mechanism induces the deformed posture of the lower extremities. Recently, some authors introduced a parameter including total body sagittal alignment, which can predict the clinical outcome better than previous parameters limited to the spine or pelvis. As a result, total body sagittal alignment needs to be considered for elderly spine deformity patients after a deformity correction operation. In conclusion, for elderly spine deformity patients, medical comorbidities and osteoporosis need to be evaluated and managed preoperatively to reduce the complication rate. In addition, total body sagittal alignment needs to be considered, which is associated with better clinical outcomes than the previous parameters limited to the spine or pelvis.

Monitoring Seasonal Influenza Epidemics in Korea through Query Search (인터넷 검색어를 활용한 계절적 유행성 독감 발생 감지)

  • Kwon, Chi-Myung;Hwang, Sung-Won;Jung, Jae-Un
    • Journal of the Korea Society for Simulation
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    • v.23 no.4
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    • pp.31-39
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    • 2014
  • Seasonal influenza epidemics cause 3 to 5 millions severe illness and 250,000 to 500,000 deaths worldwide each year. To prepare better controls on severe influenza epidemics, many studies have been proposed to achieve near real-time surveillance of the spread of influenza. Korea CDC publishes clinical data of influenza epidemics on a weekly basis typically with a 1-2-week reporting lag. To provide faster detection of epidemics, recently approaches using unofficial data such as news reports, social media, and search queries are suggested. Collection of such data is cheap in cost and is realized in near real-time. This research aims to develop regression models for early detecting the outbreak of the seasonal influenza epidemics in Korea with keyword query information provided from the Naver (Korean representative portal site) trend services for PC and mobile device. We selected 20 key words likely to have strong correlations with influenza-like illness (ILI) based on literature review and proposed a logistic regression model and a multiple regression model to predict the outbreak of ILI. With respect of model fitness, the multiple regression model shows better results than logistic regression model. Also we find that a mobile-based regression model is better than PC-based regression model in estimating ILI percentages.

A Study on the Disaster Prevention of the Royal Tomb Eureung in the Mountain Cheonjang - Estimation on Forest Fire Risk Considering Forest Type and Topography - (천장산 의릉의 방재대책에 관한 연구 - 임상과 지형인자를 고려한 산불위험성 평가 -)

  • Won, Myoung-Soo;Lee, Woo-Kyun;Choi, Jong-Hee
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.28 no.1
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    • pp.59-65
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    • 2010
  • The purpose of this study is to analyze the risk of the forest fire, considering the topography and the forest, for establishing disaster prevention measures of cultural heritage, Uireung, over in Cheonjang-mountain. To do that, we estimate the occurrence and spread of the forest fire over in Cheonjang-mountain through a forest fire probability model(logistic regression), using the space characteristic data($100m{\times}100m$). The factor, occurrence of the forest fire, are diameter class, southeast, southwest, south, coniferous, deciduous, and mixed forest. We assume the probability of the fire forest in each point as follow : [1+exp{-(-4.8081-(0.02453*diameter class)+(0.6608*southeast)+(0.507*southwest)+(0.7943*south)+(0.29498*coniferous forest)+(0.28897*deciduous forest)+(0.17788*mixed forest))}]$^{-1}$. To divide dangerous zone of the big forest fire, we make the basic materials for disaster prevention measures, through the map of coniferous forests, deciduous forests, and mixed forest. The damage of cultural heritage caused by a forest fire will be reduced through the effective preventive measures, by forecast a forest fire to using this study.

Prognostic factors influencing clinical outcome of nonsurgical endodontic treatment (비외과적 근관치료의 임상적 성공에 영향을 미치는 예측 인자들의 평가)

  • Kim, Seon-Ah
    • Restorative Dentistry and Endodontics
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    • v.35 no.6
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    • pp.436-444
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    • 2010
  • Objectives: This study aimed to assess prospectively the clinical outcome of nonsurgical endodontic treatment and identify patient- and tooth-related factors, rather than treatment-related factors, that were the best predictors of this outcome. Materials and Methods: The inception cohort comprised 441 teeth (320 patients) and 175 teeth (123 patients) were followed up for 1-2 years. Age, gender, presence of medical disease, number of canals, previous endodontic treatment, presence of sensitivity and pain, pulp vitality, swelling or sinus tract of pulpal origin on the gingiva, periapical radiolucency and tendency of unilateral bite on the affected tooth were recorded at treatment start. Results: The outcome was classified on the basis of periapical radiolucency as healed or non healed. The overall healed rate in these cases, including nonsurgical retreatment, was 81.1%. Four tooth-related factors had a negative impact in the bivariate analysis: previous endodontic treatment, necrotic pulp, preoperative gingival swelling or sinus tract of pulpal origin, and preoperative periapical radiolucency. Stepwise logistic regression analysis including patient-, tooth-related factors and level of the root canal filling as a treatment-related factor showed that preoperative gingival lesion (odds ratio [OR]: 4.4; p = 0.005), preoperative periapical radiolucency (OR: 3.6; p = 0.011), and $\leq$ 1-2 mm under root filling length (OR: 9.6; p = 0.012) were significant predictors of failure. Conclusions: A preoperative gingival lesion of pulpal origin can influence the outcome of nonsurgical endodontic treatment in addition to preoperative periapical radiolucency.

Molecular Detection of Virulence Factors in Carbapenem-Resistant Pseudomonas aeruginosa Isolated from a Tertiary Hospital in Daejeon (대전지역의 3차 병원에서 분리된 Carbapenem 내성 Pseudomonas aeruginosa의 병독성 인자 검출)

  • Cho, Hye Hyun
    • Korean Journal of Clinical Laboratory Science
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    • v.51 no.3
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    • pp.301-308
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    • 2019
  • The emergence and spread of multidrug resistant (MDR) Pseudomonas aeruginosa is a critical problem worldwide. The pathogenesis of P. aeruginosa is due partly to the production of several cell-associated and extracellular virulence factors. This study examined the distribution of virulence factors and antimicrobial resistance patterns of carbapenem-resistant P. aeruginosa (CRPA) isolated from a tertiary hospital in Daejeon, Korea. Antimicrobial susceptibility testing was performed using the disk diffusion method, and PCR and DNA sequencing were performed to determine for the presence of virulence genes. In addition, the sequence type (ST) of MDR P. aeruginosa was investigated by multilocus sequence typing (MLST). Among 32 CRPA isolates, 14 (43.8%) were MDR and the major ST was ST235 (10 isolates, 71.4%). All isolates were positive for the presence of virulence genes and the most prevalent virulence genes were toxA, plcN, and phzM (100%). All isolates carried at least eight or more different virulence genes and nine (28.1%) isolates had 15 virulence genes. The presence of the exoU gene was detected in 71.4% of the MDR P. aeruginosa isolates. These results indicate that the presence of the exoU gene can be a predictive marker for the persistence of MDR P. aeruginosa isolates.

A Comparative Study of Characteristics of the Beauty Major Students (미용대학생들의 성격특성 비교 연구)

  • Koh, Seong-Yeon
    • The Journal of the Korea Contents Association
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    • v.20 no.3
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    • pp.336-344
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    • 2020
  • The purpose of this study was to investigate the PAI profile of the beauty major students. They were used through the PAI inspection result of 298 university students located in the chungcheong province in 2019. The results are summerized as follows; First, when comparing the average scale of college students majoring in beauty with those of college students majoring in general, college students majoring in beauty displayed a higher profile type in clinical scale than those of university students in general, with significant differences in SOM and ALC. Second, SOM, PAR, AGG, SUI that were significant when comparing beauty majors and general majors to navigate the PAI scale that significantly predicts beauty majors. As a result of conducting stepwise regression analysis on the four factors as a search factor, the scale of SOM is extracted, and it becomes a diversion that can predict college students in the beauty major. Therefore, beauty majors are more obsessed with physical problems than the ordinary students, and have an impulse-oriented behavior. These results will be used as materials for selecting, managing, educating or consulting a student majoring in beauty and will provide many implications for career choices after graduation.

A Study on PAI Traits of Beauty Major Male Students (미용전공 남학생의 특성비교 연구)

  • Koh, SungYoun
    • The Journal of the Korea Contents Association
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    • v.22 no.8
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    • pp.587-595
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    • 2022
  • In this study, in order to understand the social psychological characteristics of college male students majoring in beauty, PAI tests were conducted on 163 university students located in Gyeonggi-do and Chungnambuk area in 2020. First, when comparing the average scales of men who majored in beauty and men who majored in general, the major male students of beauty showed an overall high clinically recognized type compared to students who majored in beauty, and a negative impression on a valid scale (NIM) considered treatment for physical complaints (SOM), depression (DEP) and drinking problems (ALC) on a clinical scale, and a significant difference was shown on a suicide idea (SUI) scale. Secondly, in order to navigate the PAI scale that significantly predicts beauty major male students, a stepwise regression analysis was performed using 15 significant scales as search factors in comparison between beauty major male and general major male students. As a result, physical complaints (SOM) and depression (DEP) scales were extracted, which became a factor that can predict male students in beauty major. Therefore, it can be understood that the male students in the beauty major have behavior patterns that are more obsessed with and more impulsive to physical problems than the male majors. These results will provide a lot of suggestions for the selection of future male students in beauty major, selection, management, education, consultation materials, and selection of occupations after graduation.