• Title/Summary/Keyword: 임상적 연관성

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The Reproductive Patterns and Clinical Application of Endangered Common Chimpanzees by Monitoring the Steroid Hormone Measurements in Fecal Samples (분변내 스테로이드 호르몬의 측정을 통한 멸종 위기 침팬지의 번식형태와 임상적용)

  • Jung, So-Young;Kim, Mi-Young;Jeong, Yu-Jeong;Jang, Yu-Ni;Lim, Yang-Mook;Yoon, Yong-Dal
    • Development and Reproduction
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    • v.15 no.2
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    • pp.167-172
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    • 2011
  • To monitor the reproductive patterns of endangered common chimpanzee including annual reproductive cycle, amenorrhea, breeding season, and pregnancy diagnosis, Time-Resolved Fluorescence Immuno Assay (TR-FIA) was used to trace MRH (estradiol, progesterone, testosterone) and human chorionic gonadotropin (HCG). In result of this research, age was not the important factor in determining the reproduction capability in common chimpanzee; it was rather greatly influenced by the combination of various factors such as individual's fertilizing ability, presence of obstetrical diseases, the pattern of mating behavior, and the mental communication under the introduction of a mating partner. This research will play an important role in operating conservation project for common chimpanzees and can be extended also for shedding new light on understanding human menopause and obstetrical diseases.

Sporadic Intradural Extramedullary Hemangioblastoma Not Associated with von Hippel-Lindau Syndrome: A Case Report and Literature Review (폰 히펠린다우 증후군과 관련 없는 특발성 경막 내 수외 혈관모세포종: 증례 보고와 문헌 고찰)

  • Mi-Kyung Um;Eugene Lee;Joon Woo Lee;Kyu Sang Lee;Yusuhn Kang;Joong Mo Ahn;Heung Sik Kang
    • Journal of the Korean Society of Radiology
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    • v.82 no.3
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    • pp.700-707
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    • 2021
  • Hemangioblastomas are low-grade, highly vascular tumors that are usually associated with von Hippel-Lindau syndrome. Hemangioblastomas most commonly occur in the cerebellum, and intradural extramedullary hemangioblastoma of the cauda equina is very rare, especially in patients without von Hippel-Lindau syndrome. Herein, we report a case of intradural extramedullary hemangioblastoma of the cauda equina that was not associated with von Hippel-Lindau syndrome, with a focus on its imaging characteristics and differential diagnoses. We compared the clinical presentation and imaging features of our case with those of previously reported cases in the review of the literature.

A CASE REPORT OF DENTINOGENESIS IMPERFECTA (상아질 형성 부전증에 대한 증례보고)

  • Kim, Jae-Gon;Lee, Doo-Cheol;Lee, Seung-Young;Lee, Seung-Ik;Baik, Byeoung-Ju
    • Journal of the korean academy of Pediatric Dentistry
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    • v.27 no.1
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    • pp.1-6
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    • 2000
  • Dentinogenesis imperfecta is an inherited disorder of dentin formation, usually exhibiting an autosomal dominant mode of transmission. Type I dentinogenesis imperfecta occurs in patients afflicted with osteogenesis imperfecta. Type II dentinogenesis imperfecta is not associated with osteogenesis imperfecta. Type III dentinogenesis imperfecta (Brandywine type) occurs in a racial isolate area in the state of Maryland. In all three types, teeth of both dentitions are affected with variable clinical appearances. The teeth are opalescent with the color ranging from bluish-gray to brown to yellowish. The dentin is abnormally soft, providing inadequate functional support to the overlying enamel. Although the enamel is normal, it fractures or chips away easily, exposing the occlusal and incisal dentin. The exposed soft dentin often undergoes rapid and severe functional attrition. The teeth exhibit bulb-shaped crowns with constricted cementoenamel junctions and thin roots. The teeth will exhibit varying stages of obliteration of the coronal and root pulpal chambers. The cementum, periodontal ligament and supporting alveolar bone appear normal. The enamel is normal. The mantle dentin remains nearly normal, whereas the remaining dentin is severely dysplastic. The dentinal tubules are disoriented, irregular, widely spaced, and usually larger than normal.

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A Case-Control Study on Attitudes to Dietary Life and Nutrient Intakes of Colorectal Cancer Patients in Daegu·Gyeongbuk Area (대구·경북지역 대장직장암 환자의 식생활 태도와 영양소 섭취에 관한 환자-대조군 연구)

  • Choi, Youngeun;Kim, Eunjung
    • The Journal of the Convergence on Culture Technology
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    • v.6 no.4
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    • pp.621-626
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    • 2020
  • The incidence of colorectal cancer (CRC) in Korea has been gradually increased and it has been reported that dietary life is highly associated with the development of CRC. To investigate dietary attitudes and nutritional risk factors for CRC, we analyzed food intake of 34 patients diagnosed with CRC within 1 year and 51 subjects without gastrointestinal diseases as a control reside in Daegu·Gyeongbuk Area using semi-quantitative food frequency questionnaire. The results showed that dietary regularity and variety of food intake in control subjects was better than CRC patients whereas, CRC patients eat more frequently animal and vegetable protein foods, fried foods, green and yellow vegetables, and fruits than control subjects. Nutrient intake analysis showed that Vitamin A, E, K, C, sodium, magnesium, iodine, and cholesterol intake of CRC patients was higher than control subjects. Especially, after adjusting age and sex, regression analysis showed that Vitamin K (OR = 1.022, 95% Cl 1.003-1.043, p = 0.026) and sodium (OR = 1.001, 95% Cl 1.000-1.002, p = 0.032) were identified as risk factors for CRC. In the future, verification of the relationship between these nutrients and CRC risk and appropriate nutrient education will be needed for the prevention of CRC.

Clinical Significance of Pyuria in Pediatric Patients with Febrile Urinary Tract Infection (발열성 소아 요로감염에서 농뇨의 임상적 의의)

  • Choi, Lim;Cho, Sea-Eun;Yim, Hyung-Eun;Yoo, Kee-Hwan;Hong, Young-Sook;Lee, Joo-Won
    • Childhood Kidney Diseases
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    • v.15 no.1
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    • pp.66-75
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    • 2011
  • Purpose: Early diagnosis and treatment of febrile urinary tract infection (UTI) in children is important to prevent kidney damage. This study aims to evaluate the relationship between the presence of pyuria, the severity, and underlying genitourinary anomalies in patients with UTI. Methods: We retrospectively reviewed 293 patients with febrile UTI who were admitted to Korea University Guro Hospital during the period from June, 2007 until January, 2010. We divided the patients into two groups, one with the finding of pyuria at admission, and the other without, and compared the fever duration, white blood cell counts (WBC) and C-reactive protein (CRP) in peripheral bloods, hydronephrosis, cortical defects, vesicoureteral reflux and admission period. Results: Among the 293 patients with febrile UTI, 189 patients showed findings of pyuria whereas 104 patients did not. Patients with pyuria showed an increment of WBC ($14,694{\pm}485.2$ vs. $11,374{\pm}451.2/uL$, P <0.05) and CRP ($46.9{\pm}3.9$ vs $17.1{\pm}3.6$ mg/L, P <0.05) in peripheral blood sample. The presence of cortical defects (21.7 Vs 5.8%, P <0.05) and vesicoureteral reflux (15.9 Vs 6.7%, P <0.05) was also increased in patients with pyuria compared to patients without pyuria. There were no specific differences in fever duration, admission period, and hydronephrosis. Within the group with pyuria, CRP in peripheral blood sample increased proportionally with the increment of pyuria (P <0.05). Conclusion: In patients with febrile UTI, the increment of WBC in the urine sample can be a helpful predictor for increased CRP in peripheral blood and acute pyelonephritis.

Association between Relative Preference for Vegetables and Meat and Cancer Incidence in Korean Adults: A Nationwide Population-based Retrospective Cohort Study (채소 및 육류 섭취의 상대적인 선호도와 암 발생의 연관성: 국민건강보험공단 국민건강정보자료 활용)

  • Yie, Ga-Eun;Kim, An Na;Cho, Hyun Jeong;Kang, Minji;Moon, Sungji;Kim, Inah;Ko, Kwang-Pil;Lee, Jung Eun;Park, Sue K.
    • Korean Journal of Community Nutrition
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    • v.26 no.3
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    • pp.211-227
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    • 2021
  • Objectives: We aimed to examine the association between the relative preference for vegetables and meat and cancer incidence, in a population-based retrospective cohort in Korea. Methods: We included 10,148,131 participants (5,794,124 men; 4,354,007 women) who underwent national health screening between 2004 and 2005 from the National Health Information Database of the National Health Insurance Service (NHIS-NHID). Participants were asked whether they preferred consuming 1) vegetables more often, 2) both vegetables and meat or 3) meat more often. Participants were followed up to Dec. 31, 2017. All cancer and eighteen common cancer cases were identified through the code from the International Classification of Diseases, 10th revision. We estimated sex-specific relative risks and 95% confidence intervals, adjusting for age, body mass index, alcohol consumption, smoking, physical activity, and income level. Results: During an average follow-up of 12.4 years, 714,170 cancer cases were documented. In men, consuming meat more often was associated with lower risk of esophageal, liver, and stomach cancers, but higher risk of lung and kidney cancers. Consuming both vegetables and meat was associated with higher risk of prostate cancer, but with lower risk of esophageal, liver, and stomach cancers in men. In women, consuming meat more often was associated with a higher risk of colorectal cancer and breast, endometrial, and cervical cancers diagnosed before the age of 50. Consuming both vegetables and meat was associated with lower risk of liver cancer in women. Conclusions: Our study suggests a potential link between vegetable and meat intake and cancer incidence in the Korean population. Further investigation on the association between the intake of specific types of vegetables and meat and cancer risk in Korean prospective cohort studies is needed.

Association of the Risk of Leukemia and Non-Hodgkin's Lymphoma (NHL) with Environmental Agents (모 지역의 소아 백혈병 및 악성림프종 발병 사례와 환경적 요인의 연관성 조사)

  • Park, Dong-Uk;Choi, Sangjun;Youn, Kanwoo;Kim, So-Yeon;Kim, Hee-Yun;Park, Yun-Kyung;Kim, Won;Iim, Sanghyuk;Park, Jihoon
    • Journal of Environmental Health Sciences
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    • v.45 no.3
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    • pp.203-212
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    • 2019
  • Objective: A total of five students at same middle school were reported to be diagnosed with pediatric leukemia (n=2), non-Hodgkin's lymphoma (NHL, n=1) and aplastic anemia (n=2) between 2016 and 2017. The aims of this study are to assess exposure to environmental hazardous agents known to be associated with the risk of leukemia and to examine whether the environment of school is associated with the risk leukemia. Method: A total of 11 environmental agents causing childhood leukemia were monitored using international certified method in schools where patients had ever attended. Radon & Thoron detector was used to monitor real-time airborne radon and thoron level ($Bq/m^3$). Clinician interviewed two among nine patients who agreed to participate in this study in order to examine the association of demographic and genetic factors by individually. Leukemia, NHL, and aplastic anemia were grouped into lymphohematopoietic disorder (LHP). Results: Except for airborne radon level, no environmental agents in school and household where patients may be exposed were found to higher than recommended airborne level. Clinical investigation found no individual factors that may be associated with the risk of LHP. Higher airborne radon level than Korea EPA's airborne radon criteria ($148Bq/m^3$) was monitored at most of several after-class room of one elementary school, where two leukemia patients graduated. Significant radon level was not monitored at class-room. Significant exposure to radon of patients was not estimated based on time-activity pattern. Conclusions: Our results have concluded that there have been no environmental factors in school and household environment that may be associated the risk of LHP.

The Study on the Anxiety of Dental Hygiene students on the First field Practice (첫 현장실습을 앞둔 치위생과 재학생의 불안에 관한 연구)

  • Kim, Myung-Eun;Kim, Hee-Kyoung;Kim, Sun-Il
    • Journal of Industrial Convergence
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    • v.20 no.8
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    • pp.137-144
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    • 2022
  • This study was conducted to provide the basis for psychological management direction of students ahead of their first field practice by grasping the degree of anxiety and confirming the relationship between departments satisfaction and practice expectations. A survey was conducted on dental hygiene students ahead of their first field practice and 135 people were selected as final analysis subjects. Data analysis investigated general characteristics, department satisfaction, field practice expectation and pre-education satisfaction and statistical analysis was conducted through mean(±SD), one-way ANOVA, and multiple linear regression analysis method. As a result, the anxiety level was high in the lower group of performance in the previous semester, and the department satisfaction and pre-education satisfaction were high in the group with low anxiety level. As a result of the correlation analysis, it was found that department satisfaction, field practice expectation, pre-education satisfaction, and anxiety were negatively correlated, and the higher the practice expectation, the lower the anxiety. Therefore, in order to lower the level of anxiety before field practice, it is necessary to come up with measures to increase interventional pre-education, department satisfaction and field practice expectation.

Fine needle aspiration cytology of enlarged lymph nodes in children and adolescents (소아 및 청소년에 있어서 림프절 종대에 대한 미세침 흡인 세포검사법)

  • Lee, Seung Min;Oh, Yoon Jung;Jun, Yong Hoon;Hong, Young Jin;Son, Byong Kwan;Kim, Soon Ki;Han, Jee Young;Chu, Young Chae
    • Clinical and Experimental Pediatrics
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    • v.49 no.2
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    • pp.167-172
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    • 2006
  • Purpose : Palpable lymph nodes are common in the pediatric population, and most of them are either inflammatory or congenital. As the diagnostic evaluation, fine needle aspiration cytology (FNAC) is known to be more convenient and economical than tissue biopsy. We evaluated the usefulness of FNAC in children and adolescents. Methods : Four hundred and thirteen FNAC samples(M : F=1 : 1.15) were retrospectively analyzed in patients who were brought to Inha University Hospital, from August 1999 to August 2004. Results : The most common age group was 16-20 years of age(N=148, 35.8 percent). The cervical area was the most frequently involved site(N=310, 75 percent). Non-specific lymphadenitis was the most common(N=227, 54.9 percent), followed by the benign neoplasm(N=59, 14.2 percent). Malignant tumors were 18 cases(4.3 percent), and congenital diseases were found in 10 cases(2.4 percent). In inflammatory lesions, tuberculous lymphadenitis(N=22, 5.3 percent) was the most common with a histologic sensitivity of 90.9 percent. The peripheral blood and serologic studies were non-specific. Fifty nine percent(N=244) of lymphadenitis improved without specific management. Antibiotics were prescribed in 15.2 percent of lymphadenitis and lymphadenectomy was performed in 12.6 percent. Conclusion : Most of the enlarged lymph nodes in children and adolescents were benign. These results show FNAC is a safe, rapid and reliable diagnostic procedure for the appropriate differential diagnosis of enlarged lymph nodes in children and adolescents.

Comparative Analysis of Medical Terminology Among Korea, China, and Japan in the Field of Cardiopulmonary Bypass (한.중.일 의학용어 비교 분석 - 심폐바이패스 영역를 중심으로 -)

  • Kim, Won-Gon
    • Journal of Chest Surgery
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    • v.40 no.3 s.272
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    • pp.159-167
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    • 2007
  • Background: Vocabularies originating from Chinese characters constitute an important common factor in the medical terminologies used 3 eastern Asian countries; Korea, China and Japan. This study was performed to comparatively analyze the medical terminologies of these 3 countries in the field of cardiopulmonary bypass (CPB) and; thereby, facilitate further understanding among the 3 medical societies. Material and Method: A total of 129 English terms (core 85 and related 44) in the field of CPB were selected and translated into each country's official terminology, with help from Seoul National University Hospital (Korea), Tokyo Michi Memorial Hospital(Japan), and Yanbian Welfare Hospital and Harbin Children Hospital (China). Dictionaries and CPB textbooks were also cited. In addition to the official terminology used in each country, the frequency of use of English terms in a clinical setting was also analyzed. Result and Conclusion: Among the 129 terms, 28 (21.7%) were identical between the 3 countries, as based on the Chinese characters. 86 terms were identical between only two countries, mostly between Korea and Japan. As a result, the identity rate in CPB terminology between Korea and Japan was 86.8%; whereas, between Korea and China and between Japan and China the rates were both 24.8%. The frequency of use of English terms in clinical practices was much higher in Korea and Japan than in China. Despite some inherent limitations involved in the analysis, this study can be a meaningful foundation in facilitating mutual understanding between the medical societies of these 3 eastern Asian countries.