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http://dx.doi.org/10.5668/JEHS.2019.45.3.203

Association of the Risk of Leukemia and Non-Hodgkin's Lymphoma (NHL) with Environmental Agents  

Park, Dong-Uk (Department of Environmental Health, Korea National Open University)
Choi, Sangjun (Department of Occupational Health, Daegu Catholic University)
Youn, Kanwoo (Wonjin Institute for Occupational and Environmental Health)
Kim, So-Yeon (Department of Environmental Health, Korea National Open University)
Kim, Hee-Yun (Department of Sociology, Kyunghee University)
Park, Yun-Kyung (Department of Occupational Health, Daegu Catholic University)
Kim, Won (Wonjin Institute for Occupational and Environmental Health)
Iim, Sanghyuk (Wonjin Institute for Occupational and Environmental Health)
Park, Jihoon (Institute of Health and Environment, Graduate School of Public Health, Seoul National University)
Publication Information
Journal of Environmental Health Sciences / v.45, no.3, 2019 , pp. 203-212 More about this Journal
Abstract
Objective: A total of five students at same middle school were reported to be diagnosed with pediatric leukemia (n=2), non-Hodgkin's lymphoma (NHL, n=1) and aplastic anemia (n=2) between 2016 and 2017. The aims of this study are to assess exposure to environmental hazardous agents known to be associated with the risk of leukemia and to examine whether the environment of school is associated with the risk leukemia. Method: A total of 11 environmental agents causing childhood leukemia were monitored using international certified method in schools where patients had ever attended. Radon & Thoron detector was used to monitor real-time airborne radon and thoron level ($Bq/m^3$). Clinician interviewed two among nine patients who agreed to participate in this study in order to examine the association of demographic and genetic factors by individually. Leukemia, NHL, and aplastic anemia were grouped into lymphohematopoietic disorder (LHP). Results: Except for airborne radon level, no environmental agents in school and household where patients may be exposed were found to higher than recommended airborne level. Clinical investigation found no individual factors that may be associated with the risk of LHP. Higher airborne radon level than Korea EPA's airborne radon criteria ($148Bq/m^3$) was monitored at most of several after-class room of one elementary school, where two leukemia patients graduated. Significant radon level was not monitored at class-room. Significant exposure to radon of patients was not estimated based on time-activity pattern. Conclusions: Our results have concluded that there have been no environmental factors in school and household environment that may be associated the risk of LHP.
Keywords
Benzene; radon; environmental disease; environmental agents;
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