• Title/Summary/Keyword: 임상결과

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칭량장치

  • O, Do-Seok
    • 월간산업보건
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    • s.84
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    • pp.19-24
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    • 1995
  • 우리나라는 60년대 초부터 80년대 후반까지 중화학공업의 육성에 급급한 나머지 각종 산업분야에서 사용 및 생산된 유해화학물질의 환경과 인간에 미치는 영향은 거의 무시되어왔기 때문에 80년대 후반부터 각종 유해화학물질로 인한 직업병이 노출되어 사회문제화 되었다. 따라서 시급하게 이들 유해화학물질을 관리해야 할 필요성이 대두되고 이를 위한 제도적 장치가 마련되었다. 바로 이것이 작업환경측정 및 임상검사에 대한 정도관리제도이다. 작업환경측정을 위한 정도관리는 작업환경측정에 관한 정도관리규정(노동부 고시 제 92-18호, 1992, 4, 16) 에 의거 한국산업안전공단에서 현재 매년 2회에 걸쳐 실시하고 있으며, 근로자의 임상시료에 대한 정도관리는 1977년 대한임상검사 정도관리학회에서 실시한 이래 현재까지 자율적으로 계속 실시되고 있고, 제도적으로는 근로자 건강진단 실시기준(노동부 고시 제 92-9호, 1992. 4. 2)에 의거 대한산업보건협회가 현재까지 70여개 대상기관에 대한 매년 2회를 실시하고 있다. 그러나 작업환경측정이나 임상시료에 대한 결과치의 신뢰도 증대가 요구되는 현시점에서 신뢰도 증진의 중요한 요소중의 하나인 검사기기의 정도관리는 더더욱 그 중대함을 더해가고 있으나 우리의 실정이 이를 만족시키지 못하고 검사기기에 대한 정도관리를 할 수 있는 참고할 서적이나 방법이 부족하여 관련분야의 실무자들이 많은 애로점을 갖고 있는 실정이다. 따라서 여기에서는 검사에 사용되는 각종 기기에 대한 기초원리, 사용목적, 검사순서, 적용범위, 취급상의 주의, 사용하는 입장에서의 보수관리에 대해 서술함으로써 작업환경측정이나 임상정도관리 및 기타 관련분야에서 공통으로 사용하는 검사기기에 대한 정도관리를 함으로써 더욱더 신뢰도 높은 결과를 얻는데 기여할 수 있는 것으로 기대된다. 또한 여기에 소개한 기초원리나 응용분야에서 부족한 점은 화학, 물리학 및 임상병리학 등 전문서적을 참고하여 주기 바란다.

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Lung Adenocarcinoma Mutation Hotspot in Koreans: Oncogenic Mutation Potential of the TP53 P72R Single Nucleotide Polymorphism (한국인의 폐선암 돌연변이 핫스팟: TP53 P72R Single Nucleotide Polymorphism의 발암성 돌연변이 가능성)

  • Jae Ha BAEK;Kyu Bong CHO
    • Korean Journal of Clinical Laboratory Science
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    • v.55 no.2
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    • pp.93-104
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    • 2023
  • This study aimed to identify new markers that cause lung adenocarcinoma by analyzing mutation hotspots for the top five genes with high mutation frequency in lung adenocarcinoma in Koreans by next generation sequencing (NGS) analysis. The association between TP53 mutation types and patterns with smoking, a major cause of lung cancer, was examined. The clinicopathological characteristics of lung adenocarcinoma patients with TP53 P72R SNPs were analyzed. In Korean lung adenocarcinoma cases, regardless of the smoking status, the TP53 P72R SNP was the most frequently occurring mutational hotspot, in which the nucleotide base was transversed from C to G, and the amino acid was substituted from proline to arginine at codon 72 of TP53. An analysis of the clinicopathological characteristics of lung adenocarcinoma cases with TP53 P72R SNP revealed no significant correlation with the patient's age, gender, smoking status, and tumor differentiation, but a significant correlation with low stage (P-value =0.026). This study confirmed an increase in TP53 rather than EGFR, which was reported as the most frequent mutations in lung adenocarcinoma in Koreans through NGS. Among them, TP53 P72R SNP is the most frequent regardless of smoking status.

견봉쇄골 관절 탈구의 수술적 치료

  • 이광원;송대화;최원식
    • The Academic Congress of Korean Shoulder and Elbow Society
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    • 1998.03a
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    • pp.33-33
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    • 1998
  • 저자들은 1990년 1월부터 1997년 1월까지 을지의과대학병원 정형외과에서 제3형 급성 견봉쇄골 관절 탈구로 진단받고 Phemister 방법, Bosworth 방법, Weaver and Dunn 방법등으로 수술 받은 70례의 환자에 대하여 이중 1년 이상 추시 가능하였던 60례를 대상으로 하여 임상적 및 방사선학적 분석을 시행하여 다음과 같은 결과를 얻었다. 수상후 평균 오구쇄골간격은 건측과 비교시 평균 7.1mm의 차이를 보였는데 수술 방법에 상관없이 추시시에는 평균 2mm의 차이를 보였다. 임상적 평가에서는 우수 23례$(38\%)$, 양호 31례$(52\%)$, 보통이 6례$(10\%)$를 보여 대부분 좋은 결과를 얻어 오구쇄골 간격 증가가 임상적 결과와 반드시 일치하지는 않는 결과를 가져왔다

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A Study on the Reliability of Clinical Diagnosis for TMJ Internal Derangement (측두하악관절 내장증의 임상적 진단의 신뢰도에 관한 연구)

  • 김영구;이승우;정성창
    • Journal of Oral Medicine and Pain
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    • v.23 no.1
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    • pp.37-44
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    • 1998
  • 본연구는 서울대학교 치과병원 구강진단과 악안면 동통진료실에 내원한 환자 중 임상적 검사에 의해 악관절 내장증으로 진단된 총 32명 53개의 측두하악 관절을 대상으로 악관절 조영술이나 자기공명영상을 실시하여 임상적 진단의 정확도를 알아보고 향후 이 결과를 적절히 활용하여 정확한 적응증의 설정에 도움을 주고자 시행되었다. 각 악관절을 임상적 검사, 조영술 및 자기공명영상 검사를 기준으로 정상, 정복성 관절원판 변위, 비정복성 관절원판 변위, 퇴행성 관절 질환을 동반한 정복성 관절원판 변위, 퇴행성 관절 질환을 동반한 비정복성 관절원판 변위로 구분하였다. 이상의 연구를 통하여 다음과 같은 결론을 얻었다. 1. 악관절 내장증으로 내원한 환자 32명, 총 53개 관절중, 정상인 경우가 5예, 정복성 관절원판 변위인 경우가 33예, 비정복성 관절원판 변위인 경우가 14예, 퇴행성 관절 질환을 동반한 정복성 관절원판변위인 경우가 1예이었고, 퇴행성 관절 질환을 동반한 비정복성 관절원판 변위인 경우는 없었다. 2. 악관절 조영술 검사를 시행한 35개의 관절중 임상적 검사와 일치하는 경우는 32개로 그 일치율은 91.1%이었으며, 자기공명영상 검사를 시행한 28개의 관절중 임상적 검사와 일치하는 경우는 20개로 그 일치율은 71.4%이었다. 3. 악관절 조영술 및 자기공명영상 검사를 동시에 시행한 10개 관절중 악관절 조영술 및 자기공명영상검사가 일치하는 경우는 9개이었으며 이중 8개 결과는 임상적 진단과 일치되는 소견을 보였다. 임상적 검사는 악관절 내장증의 진단에 유용한 방법임이 확인되었다. 그러나 임상적으로는 정상으로 진단되었지만 주관적인 증상을 가진 환자에게는 자기공명영상 검사와 악관절조영술 검사 등의 영상진단술식이 필요할 것으로 사료된다.

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A Study on Stress Factors Radiology Students Experience During Outdoor Clinical Training (방사선학과 학생이 교외 임상실습에서 경험한 스트레스 요인에 관한 연구)

  • Kim, Jung-Hoon;Kang, Se-Sik;Kim, Chang-Soo
    • Journal of radiological science and technology
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    • v.36 no.3
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    • pp.201-208
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    • 2013
  • This study aimed at analyzing stress factors of radiography students may experience during their clinical training, and thus at providing assistance in improving efficiency and quality of clinical training. As for the method of study, a questionnaire survey was conducted targeting radiography students from five universities in Busan and Gyeongsangnam-do regions who had clinical training experiences. The result of the survey showed that, among five stress factors, environmental factor was the highest source of stress, followed by ideals, values, roles and activity. In addition, it was found that the level of stress experienced during clinical training was higher than the level of stress in daily life. If the stress of clinical training can be reduced based on the results of this study, it will not only contribute to improving students' level of satisfaction with clinical training, but also enhance the quality of clinical training.

A Systematic Review of Domestic Research on Clinical Fieldwork in Occupational Therapy (국내 작업치료 임상실습 연구에 관한 체계적 고찰)

  • Cha, Su-Min
    • Journal of Digital Convergence
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    • v.18 no.9
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    • pp.433-440
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    • 2020
  • The purpose of this study is to analyze the research trend by conducting a systematic review of domestic research on clinical fieldwork in occupational therapy. From 2000 to 2019, papers registered in the Google Scholar, RISS, KISS, and National Library of Korea databases were searched. The search term was "Occupational Therapy" AND "Clinical Fieldwork", and a total of 8 studies were finally selected. As a result of analyzing the research trend, the most frequently used data collection method were surveys 6 studies(75.0%), and the most frequent subject were occupational therapy students was 6 studies(75.0%). The most frequent main theme was satisfaction of clinical fieldwork 4 studies(50.0%). In the future, it was confirmed that quantitative and qualitative growth of clinical research related to occupational therapy in Korea is needed.

Affecting Factors on Clinical Competence of Nursing Students (간호대학생의 임상수행능력 영향 요인)

  • Jang, Hee-Jung;Kwag, Youn-Kyoung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.9
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    • pp.4380-4387
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    • 2013
  • The purpose of this study was to investigate the level of clinical competence and influencing factors of clinical competence in nursing students. Convenience sample of 197 subjects were recruited from two colleges in D city. The survey was conducted from March 2nd to 21th 2011. The data was collected by questionnaires and was analyzed with SPSS statistics 21.0. The mean score of clinical competence was 3.96. Significant positive correlation among clinical thinking disposition, problem solving ability, major satisfaction, satisfaction with clinical practice, clinical competence were found. It was found that the effect of clinical thinking disposition, completion of logic course, problem solving ability on clinical competence was 27.2% and clinical thinking disposition influence on clinical competence in nursing students. The study findings suggest that to develop the effective learning program with achievement level of clinical competency for nursing students.

The Mediating Effect of the Resilience on the Relationship between Stress in Clinical Practice and Clinical Competence in Nursing Students (간호대학생의 임상실습스트레스와 임상수행능력의 관계에 미치는 극복력의 매개효과)

  • Kim, Ju-Yeun;Kim, Min-Kyeong;Cho, Jin Young
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.1
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    • pp.669-678
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    • 2017
  • This study aimed to identify the mediating effect of resilience on the relationship between stress during clinical practices and clinical competence in nursing students. A total of 137 senior nursing students in three different universities located in C city were included. The study period was between October 15 and November 15, 2016, and the data were collected using by structured questionnaires. Collected data were analyzed by descriptive analysis, t-test, ANOVA, Pearson's correlation, and Multiple regression using the SPSS 22.0 statistical program. The average score of stress in clinical practice, clinical competence, and resilience were $3.09{\pm}0.43$, $3.54{\pm}0.45$ of 5 and $4.93{\pm}0.66$ of 7. There were significantly negative correlations between stress in clinical practice and resilience (r=-.24, p=.005), as well as stress in clinical practice and clinical competencies (r=-.21, p=.012), while there were significantly positive correlations between resilience and clinical competencies (r=.59, p<.001). Resilience had a full mediated effect between stress in clinical practices and clinical competencies, which showed the significance upon Sobel test (Z=-3.02, p=.003). Therefore, it is suggested that various training courses and programs for strengthening resilience should be developed and applied to nursing curriculum.

The relationship between clinical practice stress, satisfaction of clinical practice, clinical performance ability and the nursing profession in nursing college students (간호대학생의 임상실습스트레스, 임상실습만족도, 임상수행능력과 간호전문직관의 연관성)

  • Park, Byung-Jun;Park, Sun-Jung;Cho, Hana
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.7
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    • pp.220-227
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    • 2016
  • This descriptive study was conducted to investigate the relationship between clinical practice stress, satisfaction with clinical practice, and clinical performance ability of nursing college students and the nursing profession. Data were collected from 240 students in the nursing college. Clinical performance ability (F=1.888, p=0.048) and the nursing profession (F=1.976, p=0.046) showed statistically significant differences depending on the satisfaction of majors. The nursing professional institution contained more population groups that were dissatisfied than satisfied with the majors. Additionally, clinical practice stress was reported to affect satisfaction by 41% of the respondents. Overall, stressful clinical practice, clinical practice satisfaction and clinical performance were found to significantly affect the degree of satisfaction by nursing students. Accordingly, the level of stress experienced during clinical training also affects the performance of clinical practice, and can therefore lead to mistakes. Thus, there is a need to develop future interventions that could reduce the stress experienced by clinical practice nursing students.

Effects by Incivility Experienced and Clinical Learning Environment of Nursing Students on Clinical Practice Stress (간호대학생이 경험한 무례함과 임상실습교육환경이 임상실습스트레스에 미치는 영향)

  • Kwak, Eun-mi;Yun, Hee-jang;Park, Min-ae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.2
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    • pp.160-168
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    • 2021
  • This study attempts to identify how incivility and clinical learning environment affects clinical practice stress among nursing students. This study enrolled 204 nursing students in the third- and fourth-grades, having practical clinical experience. Data were collected from April 1 to April 30, 2019, by the self-reported method. Data analysis was achieved by applying descriptive statistics, t-test, ANOVA, Pearson correlation coefficient, and multiple regression analysis, using the SPSS 22.0 program. Our results showed that the average values for incivility experienced by nursing students was 2.58, clinical learning environment was 2.79, and clinical practice stress was 3.33. Incivility experienced and clinical practice stress appeared to be a static correlation, whereas the clinical learning environment and clinical practice stress, and incivility experienced and clinical learning environment, were identified as amulet correlations. Incivility experienced and clinical learning environment exerted significant influences on clinical practice stress, where the explanatory power was confirmed at 22.5%. Based on the results of this study, we propose the necessity to develop and apply various programs to effectively manage the clinical practice stress of nursing students.