• Korean Journal of Psychosomatic Medicine
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• v.24 no.1
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• pp.102-108
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• 2016

Objectives : The deficit of recognition memory has been found as one of the common neurocognitive impairments in patients with schizophrenia. In addition, they were reported to fail to enhance the memory about emotional stimuli. Previous studies have shown that bilateral eye movements enhance the memory retrieval. Therefore, this study was conducted in order to investigate the memory enhancement of bilaterally alternating eye movements in schizophrenic patients. Methods : Twenty one patients with schizophrenia participated in this study. The participants learned faces (angry or neutral faces), and then performed a recognition memory task in relation to the faces after bilateral eye movements and central fixation. Recognition accuracy, response bias, and mean response time to hits were compared and analysed. Two-way repeated measure analysis of variance was performed for statistical analysis. Results : There was a significant effect of bilateral eye movements condition in mean response time(F=5.812, p<0.05) and response bias(F=10.366, p<0.01). Statistically significant interaction effects were not observed between eye movement condition and face emotion type. Conclusions : Irrespective of the emotional difference of facial stimuli, recognition memory processing was more enhanced after bilateral eye movements in patients with schizophrenia. Further study will be needed to investigate the underlying neural mechanism of bilateral eye movements-induced memory enhancement in patients with schizophrenia.

• KEPCO Journal on Electric Power and Energy
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• v.6 no.3
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• pp.259-269
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• 2020

With the proposal-agreement procedure, RSTP can reduce the network recovery time to 400 ms or less in the case of 40 bridges. While the legacy RSTP reverts the previous agreement at the bridge with the alternate port role in the ring during the fault recovery, a new position based fast fault recovery procedure is proposed in this paper to guarantee a single proposal-agreement transaction which can provide more faster recovery. By knowing the relative position of the faulty link or bridge in hops, the bridge on the middle of the ring can complete the recovery procedure without revert. The performance of proposed procedure is numerically calculated and verified by simulation and the result shows that the recovery time can be reduced up to 100 ms, which is 1/4 times of the legacy RSTP.

• The Journal of the Korea Contents Association
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• v.13 no.6
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• pp.339-349
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• 2013

This study was conducted to evaluate the correlation between the Korean version of Mini Mental State Examination (MMSE-K) and the Korean Computerized Neurobehavioral Test (KCNT) and the usefulness of KCNT for discriminating the patients with suspected dementia from normal persons in patients with a brain injury. The results of each items of KCNT had passed the test for normality. T test for group comparison and bivariate correlation analysis for correlation between two tests were used. There were no significant differences in characteristics of two groups. The differences in results of eight tests of KCNT between two groups were statistically significant (p<.05) and the Pearson correlation coefficients (r) between two tests were statistically significant (p<.05) : simple reaction time (-.580), choice reaction time (-.341), color word vigilance (-.661), digit classification (-.703), 2-digit addition (-.582), 3-digit addition (-.610), symbol digit substitution (-.642), and digit span (.807). These results suggested that simple reaction time and 2-digit addition were useful in discriminating the patients with suspected dementia from normal persons because the Pearson correlation coefficients of the two items of KCNT showed anticlastic association between two groups. And each items of KCNT may use in follow up cognitive function for patients in two groups.

• Science of Emotion and Sensibility
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• v.25 no.2
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• pp.11-22
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• 2022

As social beings, we need to understand others' actions as quickly and accurately as possible. Action understanding can occur at many levels. We sometimes grasp others' intentions unintentionally. Other times, however, we have to expend effort to draw inferences about their goals. In the context of joint action, the joint Simon effect demonstrates that actors are influenced by the unintended representation of a co-actor's actions. This effect has been described as quasi-automatic, but it is unclear if the effect is automatic enough to be immune to cognitive load. Thus, we asked participants to complete a joint Simon task with or without a concurrent working memory task. One group of participants maintained a single digit in their mind during working memory load blocks (low-load group), while the other group maintained five digits (high-load group). As a result, the low-load group showed a joint Simon effect both during no-load and low-load blocks. In contrast, the high-load group had no joint Simon effect during either no-load or high-load blocks. These results suggest that the joint Simon effect is not an automatic phenomenon given that it requires cognitive resources. Actors in a joint task may represent a co-actor's actions in their task set, but only when cognitive resources are available.

• Korean Journal of Cognitive Science
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• v.31 no.2
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• pp.25-54
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• 2020

While there is no evidence for parafoveal processing in alphabetic languages such as English and Finnish, there is some evidence that morphological information is processed in syllabic languages like Chinese. Korean writing system, Hangul, would be able to provide morphological preview benefit effects since it is an "alphabetic syllabary" which contains both alphabetic and syllabic features. This study explored morphological parafoveal preview benefit effects during reading Korean using irregular verbs, which have phonological and orthographical differences between fundamental and conjugated forms. In the Experiment, the target word was irregular conjugated form, and there were four preview conditions: identical (e.g. 구워), fundamental form (e.g. 굽다), orthographically related (e.g. 굼다), and unrelated control (e.g. 죨어). In the result of study, identical was shortest and morphological, orthographical, unrelated preview were followed. Moreover, measures of first-pass reading of morphological preview were significantly shorter than those of unrelated control preview. This results support the hypothesis of morphological preview benefit effects in Korean. The implications of the results are discussed.

• The Journal of the Korean Society for Microbiology
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• v.14 no.1
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• pp.79-87
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• 1979

The immunosuppressive activity of newcastle disease virus(NDV) and some possible role of interferon(C-IF) in viral suppression of immune response were evaluated by SRBC-induced delayed-type hypersensitivity(DTH), rosette formation in spleen cells, number of lymphocytes in peripheral blood, hemagglutinin and hemolysin response to SRBC in ICR mice sensitized with SRBC. When NDV was inoculated before or after sensitization of mouse with SRBC, virus caused a marked inhibition of DTH, and its depressive effect was dependent on the time of virus inoculation in relation to SRBC sensitization or challenge. Rosette formation of spleen cells was significantly reduced by NDV infection. The degree of the depression of rosette formation was more prominent in mice inoculated before sensitization than after sensitization and could be related to the amount of serum interferon induced by the virus. Humoral response to SRBC of virus infected mouse was significantly depressed when NDV was inoculated 24 or 48 hours before sensitization. However, there was no difference in the response when the virus was inoculated 9 hour before and at the same time of sensitization or even after that. Lymphocytes in peripheral blood of mice were markedly diminished in numbers when NDV was inoculated 48 and 24 hour before sensitization with SRBC, but they were slightly augmented when the virus was inoculated 9 hour before and at the same time of sensitization. When UV-inactivated or heat-inactivated NDV was injected to the mouse at the same time of sensitization with SRBC, DTH and rosette formation of spleen cells were slightly depressed. DTH and rosette formation in mice treated with crude-IF were generally depressed as com pared with those of control mice. These studies suggest that the NDV causes a significant depression of cell-mediated immunity, whereas the humoral immune response is not inhibited markedly, and that the depression of immune response by NDV infection may be caused by interferon produced by NDV and direct viral activity.

• Journal of Oral Medicine and Pain
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• v.30 no.1
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• pp.69-77
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• 2005

The purposes of this study were to develop and introduce a novel intraoral appliance for bruxism composed of power switch and biofeedback device and further to examine inter- and intra-reliability of the appliance prior to clinical tests. The newly-developed appliance consisted of detection sensors, a central processing unit (CPU), a reactor and a storage unit and a displayer. Compact-sized, waterproof switches were selected as bruxism detection sensor and any sensor activation by clenching or grinding event was processed at the CPU and transmitted, by radio wave, to the reactor and storage unit and triggered auditory or vibratory signal, subsequently producing biofeedback to the patient with bruxism. The data on bruxing event in the storage unit can be displayed on the computer, making it possible analyzing frequency, duration and nature of bruxism. Cast models were obtained from ten volunteers with normal occlusion to evaluate reliability of the appliances. For inter-operator reliability on the intraoral appliances, each operator of the two fabricated the appliance for the same subject and compared the minimal contact forces provoking auditory biofeedback reaction in vertical, lateral and central directions. Intra-operator reliability was also investigated on the appliances made by a single operator at two separate times with an interval of two days. Conclusively, the newly-developed appliance is compact and safe to use in oral circumstance and easy to make. Furthermore, it had to be proven reliability excellent enough to apply in clinical settings. Thus, it is assumed that this appliance with the processor and the storage of data and auditory or vibratory biofeedback function is available and useful to analyze and control bruxism.

• Journal of Periodontal and Implant Science
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• v.36 no.3
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• pp.579-590
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• 2006

1. 연구배경 교원질 분해작용을 하는 호중구의 세포질 효소인 기질금속단백분해효소-8은 치주질환, 류마티스 관절염, 그리고 궤양결장염과 같은 염증성 질환에서 농도가 증가한다고 알려져 있다. 최근에는 A. actinomycetemcomitans의 leukotoxin이 사람호중구에서 기질금속단백분해효소-8의 분비를 유도하는 것이 보고되었다. 이 연구의 목적은 선천면역 체계에서 세포표면 항원무리14, Toll-like 수용기, 그리고 $NF-{\kappa}$ B경로를 통하여 A. actinomycetemcomitans의 지질다당질로 유도된 기질금속단백분해효소-8의 분비 여부와 세포기전을 알아보고자 하였다. 2. 연구재료 및 방법 건강한 개인 제공자(남자 13명, 여자 3명)로부터 얻은 개개인의 20ml 말초혈액을 제조사의 지침에 따라 호중구를 추출한 후 항세포표면 항원무리14와 함께 $4^{\circ}C$에서 30분간 전배양 한 후, $37^{\circ}C$에서 9시간 동안 배양시켰다. 추출한 호중구에 Toll-like 수용기 억제제 또는 $NF-{\kappa}$ B억제제인 TPCK를 첨가한 후 $37^{\circ}C$에서 1시간 동안 전배양하고 $37^{\circ}C$에서 9시간 동안 배양시켰다. 호중구에 세포뼈대 억제제인 cholchicine, nocodazole, demecolcine, 그리고 cytochalasin B를 A. actinomycetemcomitans의 지질다당질과 함께 $37^{\circ}C$에서 9시간 동안 배양시켰다. 기질금속단백분해효소-8 분비량은 효소면역측정법을 통해 결정하였다. 통계처리는 일원배치 분산분석법을 이용하였다(p<0.05). 3. 결과 A. actinomycetemcomitans 지질다당질은 기질금속단백분해효소-8의 분비를 증가시켰다. 기질금속단백분해효소-8의 분비는 항세포표면 항원무리14에 의해서 억제되었지만, 항 Toll-like 수용기2, 항 Toll-like 수용기4 항체는 억제시키지 못했다. $NF-{\kappa}$ B 억제제는 A. actinomycetemcomitans의 지질다당질로 유도된 $NF-{\kappa}$ B 결합 활성도와 기질금속단백분해효소-8 분비를 억제하였다. 미세섬유 중합반응 억제제는 A. actinomycetemcomitans의 지질다당질로 유도된 기질금속단백분해효소-8의 분비를 억제시켰으나, 미세관 중합반응억제제는 억제시키지 못했다. 4. 결론 위의 연구결과를 종합하여 볼 때, 기질금속단백분해효소-8은 A. actinomycetemcomitans의 지질다당질로 유도되며, 세포표면 항원무리-$NF-{\kappa}$ B 경로를 통하여 분비되고, 이 분비 과정은 미세섬유 계통이 관여하는 것으로 보인다.

• Fire Science and Engineering
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• v.34 no.3
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• pp.35-42
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• 2020

The accurate prediction of fire detector activation time is required to ensure the reliability of fire modeling during the safety assessment of performance-based fire safety design. The main objective of this study is to determine the activation temperature and the response time index (RTI) of a fixed heat detector, which are the main input factors of a fixed-temperature heat detector applied to the fire dynamics simulator (FDS), a typical fire model. Therefore, a fire detector evaluator, which is a fire detector experimental apparatus, was applied, and 10 types of domestic fixed-temperature heat detectors were selected through a product recognition survey. It was found that there were significant differences in the activation temperature and RTI among the detectors. Additionally, the detector activation time of the FDS with the measured DB can be predicted more accurately. Finally, the DB of the activation temperature and RTI of the fixed-temperature heat detectors with reliability was provided.

• Korean Journal of Cognitive Science
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• v.23 no.2
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• pp.165-184
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• 2012

To investigate how the valence of unattended background picture modulates perceptual processing of a target letter, participants were required to detect a target letter among six letters superimposed on an IAPS picture. Perceptual load was manipulated by varying the difficulty of letter detection, and behavioral results showed more accurate and faster detection responses at the low-load condition than at the high-load condition. The analysis of ERP data of control condition at which six letters were presented without an IAPS picture showed perceptual load effects on mean amplitude of N1 and P1 ERP components. At experimental condition including an IAPS picture, interaction between valence and perceptual load was observed on mean amplitude of N1 at posterior visual processing area, and the amplitude difference between low-load condition and high-load condition was larger on a negative background picture than on a neutral background picture. The results suggest that more attentional capacity might be consumed by a negative picture than by a neutral picture, and suggest that unattended affective picture is processed automatically and influence the early perceptual processing of target stimulus.