• Title/Summary/Keyword: 이식환자

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Endocrine dysfunction after bone marrow transplantation during childhood and adolescence (소아 및 청소년기에서 골수이식 후에 발생할 수 있는 내분비 기능 부전)

  • Jin, Hye Young;Choi, Jin-Ho;Im, Ho-Joon;Seo, Jong-Jin;Moon, Hyung-Nam;Yoo, Han-Wook
    • Clinical and Experimental Pediatrics
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    • v.53 no.3
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    • pp.420-427
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    • 2010
  • Purpose : Several complications can occur in patients who received bone marrow transplantation (BMT) during childhood and adolescence. This study aims to investigate endocrine dysfunctions after BMT so that better care can be provided to care for long-term survivors of BMT. Methods : One hundred patients (61 males, 39 females) were included in this study. Clinical parameters such as initial diagnosis, age at BMT, conditioning regimen, presence of graft-versus-host disease (GVHD), growth pattern, thyroid function, and pubertal status were retrospectively reviewed to evaluate risk factors associated with endocrine dysfunction. Results : Height standard deviation score (SDS) at BMT, after 1 year of BMT, and at the last visit were $0.08{\pm}1.04$, $-0.09{\pm}1.02$, and $-0.27{\pm}1.18$, respectively (P =0.001). Height SDS significantly decreased in patients who received total body irradiation (TBI) (P =0.017). One of the patients who received TBI demonstrated growth hormone deficiency. Thirty (31.9%) of 94 patients had compensated hypothyroidism. Incidence of compensated hypothyroidism was higher among those who had GVHD (odds ratio 2.82, P =0.025). Of the 32 patients (17 males, 15 females) who were over 14 years in male and 13 years in female at the last visit, 16 (3 males, 13 females) had increased luteinizing hormone (LH) or follicle-stimulating hormone (FSH). Abnormal elevation of LH or FSH was more common in females (odds ratio 30.3, P =0.001). Conclusion : The most common endocrine dysfunction was ovarian insufficiency. Regular check-up for endocrine function needs to be required due to high incidence of endocrine dysfunction in patients with BMT.

Autotransplantation of an impacted maxillary canine using Rapid Prototyping : A case report (Rapid Prototyping을 이용한 상악 매복 견치의 자가이식 치험례)

  • Cho, Nan-Ju;Lee, Nan-Young;Lee, Sang-Ho
    • Journal of the korean academy of Pediatric Dentistry
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    • v.34 no.3
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    • pp.498-505
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    • 2007
  • Management options for impacted maxillary canines can include (1) continued observation, (2) extraction of the primary canine to aid spontaneous eruption, (3) uncovering and bonding of the impacted tooth and its eruption using orthodontic traction, (4) autotransplantation, and (5) extraction followed by prosthetic replacement. Autotransplantation should be considered when the degree of malposition is too severe to correct by orthodontic alignment. The present report describes the management of an ectopic eruption of the left maxillary canine in an 10-year-old girl. The treatment included the extraction of primary maxillary left canine and the autotransplantation using a Rapid Prototyping model. By using RP model to contour the recipient bone and check for fitting in the prepared socket, the extra-oral time can reduce. The autotransplanted canine showed mobility within normal limit, negative response to percussion and positive to electric pulp test after 6 months.

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Autologous Chondrocyte Implantation (자가연골 세포이식)

  • Jeong, Hwa-Jae
    • Journal of the Korean Arthroscopy Society
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    • v.12 no.3
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    • pp.159-166
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    • 2008
  • Articular cartilage is a unique tissue with no vascular, nerve, or lymphatic supply. This uniqueness may be one of the reasons why chondral injuries will hardly heal and may progress to osteoarthritis over time. Currently, there are several surgical options for the treatment of articular cartilage lesions. Although there is some discrepancy as to which procedures work best in certain patients. The spectrum of treatment alternatives for articular cartilage defects can range from simple lavage and debridement, drilling, micro-fracturing, and abrasion to osteochondral grafting and autologous chondrocyte implantation. In 1984, for the first time, results of autologous chondrocyte implantation in a rabbit model were presented, showing hyaline cartilage repair. Clinical study using autologous cultured chondrocyte implantation in chondral defects of the human knee has been reported in 23 patients in 1994. In 14 out of 16 patients treated for chondral injuries on the femoral condyles, the results were good to excellent. It is important for the surgeon to understand the autologous chondrocyte implantation technique and to be aware on the postoperative management. Attention to surgical technique and selection of appropriate patient for the autologous chondrocyte implantation will provide with the best results.

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A Bucket Handle Tear after Revisional Meniscal Allograft Transplantation in Lateral Meniscus - A Case Report - (외측 반월상 연골 재이식술 후 발생한 양동이형 파열 - 증례 보고 -)

  • Yang, Jae-Hyuk;Kim, Taik-Sun;Park, Sung-Bum;Yoon, Jung-Ro
    • Journal of the Korean Arthroscopy Society
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    • v.16 no.1
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    • pp.56-59
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    • 2012
  • Meniscal allograft transplantation (MAT) is an accepted treatment for the symptomatic postmeniscectomized knee in younger patients. However, the likelihood of a successful outcome is reduced by various complications. One of the complications after MAT is manifested as grafted meniscal tear. However, a bucket handle meniscal tear (BHMT) following MAT is an uncommon complication and furthermore a BHMT after revisional MAT (RMAT) is a extremely rare complication. We encountered a case of BHMT after RMAT in a lateral meniscus. Retrospectively reviewing the case, we could assume the cause, which would be helpful to prevent the complication in further MAT procedures.

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당뇨병 환자의 신장이식 및 시술 후 관리

  • Gwak, Im-Su
    • The Monthly Diabetes
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    • s.184
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    • pp.28-32
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    • 2005
  • 당뇨교육, 식사 및 운동요법, 지속적인 혈당측정과 3개월 마다 A1c를 측정하고 소변검사로 미세알부민뇨를 확인하고 안저 검사와 규칙적인 발 관리를 계속하고 매년 심혈관계 합병증에 대한 검사 등 일반적인 당뇨관리를 계속한다. 이식 후 새로 생긴 당뇨병은 제2형 당뇨병 관리와 같이 관리한다.

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Neuro-muscular Pedicle Graft in Bilateral Vocal Cord Palsy (신경-근 이식을 통한 양측성 성대마비의 치료)

  • 우훈영;정현수;김영기
    • Proceedings of the KSLP Conference
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    • 1994.06b
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    • pp.89-89
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    • 1994
  • 양측성 성대마비의 수술적 치료는 여러 가지가 알려져 있으나 원인을 알 수 없는 양측성 성대마비인 경우 견갑설골근과 경계제신경을 이용한 신경-근 이식으로 좋은 결과를 얻을 수 있는 것으로 알려져 있다. 저자들은 양측성 성대마비 환자 3례를 신경-근 이식을 이용하여 수술하였기에 보고하는 바이다. (중략)

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Trough방법에 의한 광범위 기관 협착의 치료

  • 김광현;변성완;문병권
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1995.04a
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    • pp.89.2-89
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    • 1995
  • 일반적으로 기관협착의 치료는 기관절재후 단단문합술로 가능하나 광범위한 기관협착이 발생하였을 때는 그 치료가 매우 어렵다. 이경우는 기도전벽을 개방하여 경부 피부와 기관연을 봉합하는 Trough를 형성한 뒤 이차적으로 연골이식이나 경부 피부를 이용한 피판을 만들어서 기관을 재건하는 Trough방법이 주로 적용되고 있다. 이 때 이식되는 연골은 늑연골 이나 비중격 연골이며 측벽의 재건에는 늑연골이 좋고 전벽의 재건에는 점막이 붙어 있는 비중격 연골의 복합이식편이 사용될 수 있다. 본 교실에서는 기관 절제 후 단단문합술이 불가능하였던 5명의 환자에서 Trough방법을 이용하여 기관 재건에 성공하였기에 그 결과를 보고하고자 한다.

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Bypass of Superior Vena Cava with Spiral Vein Graft (Spiral Vein Graft를 이용한 상대정맥 우회로 조성술-치험 1례-)

  • Hwang, Su-Hui;Kim, Byeong-Jun;Jeong, Seong-Un
    • Journal of Chest Surgery
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    • v.30 no.3
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    • pp.344-347
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    • 1997
  • A 49-year-old female patient who had obstruction of superior vents cave(SVC) with SVC syndrome was successfully managed by bypass operation of superior vents cava with spiral vein graft. A composite spiral vein graft was placed between the right innominate vein and the right atrium to bypass the occluded SVC. The graft was constructed from the patient's own saphenous vein, which was split longitudinally and wrapped around a stent in spiral fashion and the edges of the vein were sutured together to form a large autogenous conduit. The patient was relieved o SVC obstructive symtoms and signs and discharged 21 days postoperatively without any complication.

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Effect of Cryopreservation of Sibling 2PN Zygotes on Cumulative Delivery Rates in the Human IVF-ET Program (전핵 시기에서의 수정란 동결이 체외수정 및 배아이식술에서의 누적 분만율에 미치는 영향)

  • Kim, Myo-Kyung;Lee, Sun-Hee;Choi, Su-Jin;Choi, Hye-Won;Park, Dong-Wook;Lim, Chun-Kyu;Song, In-Ok;Lee, Hyoung-Song
    • Clinical and Experimental Reproductive Medicine
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    • v.37 no.4
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    • pp.329-338
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    • 2010
  • Objective: This study was carried out to know whether cryopreservation of sibling 2PN zygotes could increase the cumulative delivery rates in the patients who had less than 10 fertilized zygotes. Methods: A retrospective analysis was performed in 138 in vitro fertilization-embryo transfer (IVF-ET) cycles with less than 10 fertilized zygotes during January 2003 to December 2007 in Cheil General Hospital. These cycles were divided into two groups. In Group I (n=86), all fertilized embryos were cultured to transfer on day 3 without cryopreserved embryos at the 2PN stage. In Group II (n=52), among fertilized zygotes, some sibling zygotes were frozen at the 2PN stage, the remainder were cultured to transfer. Clinical outcomes in fresh ET cycles and cumulative ongoing pregnancy rates after subsequent frozen-thawed (FT)-ET cycles were compared. Results: There were no significant differences in female mean age, number of retrieved oocytes and total fertilized embryos between two groups, Number of cultured embryos was significantly lower in Group II ($5.2{\pm}0.5$) than in Group I ($8.4{\pm}0.7$) (p<0.01). Also, number of transferred embryos was significantly lower in Group II ($3.3{\pm}0.6$) compared with Group I ($3.6{\pm}0.6$) (p<0.01). ${\beta}$-hCG positive rates and delivery rates (51.2 vs. 46.2 % and 41.9 vs. 34.6 %, respectively) after fresh ET were slightly higher in Group I than in Group II. However, the differences were not statistically significant. Also, the cumulative delivery rates after subsequent FT-ET cycles were not significantly different between Group I (48.8%) and Group II (50.0%). Conclusion: This study showed that cryopreservation of sibling 2PN zygotes from patients who had less than 10 zygotes in the fresh ET cycles did not increase cumulative delivery outcomes. But, it could provide an alternative choice for patients due to offering more chance for embryo transfers if pregnancy was failed in fresh IVF-ET cycles.

Heart Transplantation Performed in a Patient with Isolated Cardiac Sarcoidosis (심장에 국한된 유육종증 환자에서 시행된 심장 이식)

  • Cho, Hyun Jin;Jung, Sung-Ho;Yun, Tae-Jin;Moon, Dukhwan
    • Journal of Chest Surgery
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    • v.42 no.1
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    • pp.92-95
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    • 2009
  • Sarcoidosis is a systemic inflammatory disease with granulomatous lesions, and cardiac involvement occurs in 20~60% of patients. Isolated cardiac sarcoidosis is extremely rare, and heart transplantation can be performed, if indicated, contingent upon the absence of systemic manifestations of the disease. We present a case of isolated cardiac sarcoidosis with progressive heart failure, which was successfully managed by heart transplantation.