• Prospectives of Industrial Chemistry
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• v.22 no.1
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• pp.23-37
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• 2019

미용기능식품은 최근 이너뷰티식품으로도 일컬어지며, 일시적이고 인위적인 방법이 아닌 음식 섭취를 통해 건강과 아름다움을 가꿀 수 있는 식품이다. 기존에 이너뷰티식품은 건강기능식품 중 하나로 인식되었으나 천연재료의 미용효과를 강조한 다양한 식품들이 출시되면서 점차 이너뷰티 식품군이 확대되고 있는 추세이다. 국내에서는 자생식물과 약용식물을 함유한 건강즙, 디톡스음료, 착즙 주스 등의 제품이 항산화 및 피부건강과 같은 마케팅 진행으로 인기를 얻고 있다. 그러나 아직 이너뷰티식품 기업 대부분이 안정적인 매출과 인지도를 구축하지 못하고 있는 상황이며, 대체적으로 중견기업 이상의 기업들이 점유하고 있는 상황이므로 인지도가 낮은 브랜드들은 적극적인 수출활동을 진행하지 않고 있다. 한편 전 세계적으로 이너뷰티식품의 카테고리가 다양화되고 타깃 소비층이 증가하고 있으므로, 적절한 제품 및 마케팅 전략 수립을 통해 시장을 확대해가는 전략이 필요한 상황이다. 따라서 본 기고에서는 이러한 이너뷰티제품의 소재 및 연구방향, 시장동향들을 소개하고자 하며, 이를 통해 이너뷰티식품이 향후 발전해 나아갈 방향을 제시하고자 한다.

• Journal of the Korean Applied Science and Technology
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• v.37 no.5
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• pp.1180-1189
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• 2020

This study attempted to investigate the physiological activities of Passiflora caerulea extract and provide basic data needed to verify its availability as an inner beauty material. To examine its anti-oxidant, anti-inflammatory and anti-aging effects, the followings were measured: total polyphenol contents, total flavonoid contents, DPPH radical scavenging activity, cytotoxicity and NO inhibition effects in RAW 264.7 macrophage cells and HDF cells and MMP-1 inhibitory effects in HDF cells. The results found the followings: First, polyphenol and flavonoid contents were great with 157 mg/g and 173.5 mg/g respectively at 10mg/mL, and DPPH radical scavenging activity was confirmed. In RAW 264.7 macrophage cells and HDF cells, no cytotoxicity was observed for Passiflora caerulea extract. In addition, 69.3% anti-inflammatory effects were found at 100 ㎍/mL through NO inhibition in RAW 264.7 macrophage cells. In addition, a significant inhibition of MMP-1 expression in HDF cell was confirmed. The above results confirmed the anti-oxidant and anti-inflammatory effects of Passiflora caerulea extract, low toxicity on skin cells and its anti-aging effects by inhibiting MMP-1 expression. Therefore, it appears that Passiflora caerulea extract would be available as diverse inner beauty materials.

• Journal of Convergence for Information Technology
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• v.10 no.3
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• pp.217-226
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• 2020

The study was conducted to investigate the improvement nail health in middle-aged women aged 40~60 years who intake soybean koji by incubating Aspergillus oryzae(황국균), and utilized non-fermented soybeans as a control group and soybean koji as an experiment group for eight weeks. After clinical trials, the lifting and cracking conditions of the nails in the experiment group were improved, The moisture content increased 5.1 times compared to the control group, The water loss was 1.4 times less the reduction to the control group. and nail thickness increased by 1.9 times compared to controls. Wrinkles on the surface improved by about 2.4 times compared to the control group. In conclusion, consumption of this soybean koji of A. oryzae's has been shown to have an impact on improving nail is expected to be used Therefore, I propose this soybean koji of A. oryzae's as an inner beauty for improving nail is in middle-aged women aged 40~60 years.

• Journal of the Korea Convergence Society
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• v.12 no.8
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• pp.301-308
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• 2021

In this study, the antioxidant and anti-inflammatory, anti-obesity properties, of Sargassum macrocarpum extracts were identified to assess the availability of Sargassum macrocarpum extracts as cosmetics and foods. To measure antioxidant activity, we conducted TPC, TFC, DPPH, ABTS, NO, FRAP. For polyphenols, 30.81±1.12 mg/g was shown. Flavonoids showed 25.72±0.94 mg/g. The DPPH experiment showed an antioxidant function of 6.746 mg ascorbic acid/g extract, the ABTS experiment showed an antioxidant function of 15.59 mg ascorbic acid/g extract, and the NO experiment showed an antioxidant function of 6.781 mg ascorbic acid/g extract. In FRAP, 1 mg of the Sargassum macrocarpum extract showed a reduction of 4.573±0.097 ㎍ of ascorbic acid. In cytotoxicity experiments, Sargassum macrocarpum extracts showed a cell survival rate of more than 80% at all concentrations, and an inflammatory inhibition of 25.95±0.85%, and an lipid accumulation inhibition of 29.75±2.35%. These results indicate that Sargassum macrocarpum extract is available as an anti-inflammatory cosmetic and anti-obesity inner beauty material. In future studies, it is necessary to study how pure substances containing Sargassum macrocarpum extract affect antioxidants, anti-inflammatory and anti-obesity

• KSBB Journal
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• v.32 no.1
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• pp.1-8
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• 2017

Bamboo is a plant belonging to the Gramineae family, and can be used as valuable bioresources for many industrial applications. Bamboo has some useful properties and having a lot of beneficial uses such as a bamboo ware, agriculture material, building construction material, pulpwood, etc. Bamboo stem has a large amount of active ingredients that those of bamboo leaves. The stem of bamboo can be processed into various biomaterials including cellulose and lignin, and sometimes uses as foods, cosmetics and medicines using stem extracts with polyphenol compounds. For cosmetic applications of bamboo stems, especially, the constituents of bamboo stem are suitable for inner beauty (cosmetic food) products showing antioxidant and UV-protecting activities. This review summaries the recent literature data and discusses the versatile uses of bamboo stem and its extracts mainly for cosmetic application.

• Journal of Life Science
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• v.33 no.7
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• pp.555-564
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• 2023

In this study, the anti-oxidant activity, elastase inhibitory activity, and skin moisturizing effect of mixed extracts of Acanthopanax senticosus and Citrus unshiu fermented with Bovista plumbea (B-MEAC) were evaluated to verify the availability as a material for inner beauty. The DPPH radical scavenging activity of B-MEAC was showed in a dose-dependent manner (SC₅₀=156.1±0.82 ㎍/ml). Also, B-MEAC inhibited the elastase activity in a concentration-dependent manner (p<0.001). To study the effect of B-MEAC on mouse skin hydration, skin moisture content and transepidermal water loss (TEWL) measured. As a result, skin moisture content increased (p<0.001) and TEWL decreased (p<0.01) compared to the dry-induced control group. The effect on the change of collagen fibers in the dry-induced mouse skin was examined through Masson's trichrome staining. In the group administered with B-MEAC, the amount of collagen relatively increased compared to the control group, and the intensity of blue color increased. The effect on the moisturizing function of the dry-induced mouse skin was examined by Western blot method. In the group administered with B-MEAC, the expression of matrix metalloproteinase-1 (MMP-1) protein decreased compared to the control group. In addition, the expression level of collagen1A1 (COL1A1), hyaluronan synthase-2 (HAS2), filaggrin, and aquaporin-3 (AQP3) recovered (p<0.001). Therefore, these results suggest the potential of B-MEAC as a skin hydration agent for inner beauty.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.20 no.11
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• pp.2033-2038
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• 2016

Big data analysis, in the large amount of data stored as the data warehouse which it refers the process of discovering meaningful new correlations, patterns, trends and creating new values. The important issue of a meta-analysis is not the significance test, the effect size of the predictor variable on the criterion variable. We reviewed a total of 236 samples among 6 studies published on the topic related Collagen intake on skin between 2000 and 2016 in Korea. The results of the study are summarized as follows. First, we concluded that the path between before and after of Sebum (SB) had the largest effect size of (r = .416) Therefore, the effect of the Collagen intake intervention showed an explanatory power of 17 (%) about. Next, the path between before and after of Moisture (MS) had the higher the effect size of (r = .318). Thus, we present the theoretical and practical implications of these results.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2022.09a
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• pp.25-25
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• 2022

피부 노화는 피부와 피부 지지층 등의 광범위한 퇴행 과정을 말한다. 피부 노화의 원인은 흡연, 공해, 스트레스 등이 있지만, 그 중에서도 자외선(ultra violet, UV) 조사가 가장 큰 요인으로 꼽힌다. 반복적인 자외선 조사에 의해 진행되는 피부노화를 광노화라고 하며 그 가장 큰 특징으로는 콜라겐 섬유와 엘라스틴의 감소로 야기되는 주름을 들 수 있다. 본 연구에서는 제주에서 채집한 바위수국의 추출물 및 분획물의 항산화 및 자외선으로 인한 피부노화 예방(anti-photoaging) 효능을 확인하고, 활성물질을 분리하여 광노화 예방 효능과 그 메커니즘을 확인하였다. 실험에 사용된 바위수국은 범의귀과의 덩굴성 식물로 바위면이나 나무줄기 등에 붙어서 자라며, 한국(제주, 울릉도)과 일본에 분포한다. 바위수국 추출물과 분획물에서 총 페놀 함량. 총 플라보이드 함량, DPPH 및 ABTS 라디칼소거 활성의 항산화 실험 결과, 부탄올과 에틸아세테이트 분획층에서 강력한 항산화 활성이 관찰되었다. 또한 UVA를 조사한 인간 진피 섬유아세포 (human dermal fibroblast, HDF)데 대한 콜라겐 분해효소인 matrix metalloproteinase-1(MMP-1) 생성 억제 활성을 확인한 결과, 부탄올 분획층이 세포 생장 저해 없이 가장 우수한 효능이 확인되었다. 따라서 부탄올 분획층에서 주요 성분 분리 실험을 수행하여 총 4개의 화합물을 분리하였다; Chlorogenic acid (1), Quercetin-3-O-glucosyl-(1-2)-rhamnoside (2), Quercetin-3-O-xylosyl-(1-2)-rhamnoside (3), Quercitrin (4). 분리한 4개의 물질의 MMP-1 생성 억제 활성을 비교한 결과 화합물 2가 세포독성 없이 MMP-1 생성 억제 효능이 우수하였고, 이후 화합물 2의 광노화 예방 효능과 그 메커니즘을 확인하였다. 화합물 2는 MMP-1의 생성을 억제할 뿐만 아니라 procollagen type I의 생성을 증가시켰으며, MMP-1 생성에 관여하는 mitogen-activated protein kinase (MAPK)/activator protein-1 (AP-1) 신호전달경로를 하향 조절하며, 콜라겐 생성과 관련된 Transforming growth factor-β (TGF-β)/Smad 신호전달경로를 상향 조절하여 UVA에 의한 광노화 예방에 효능을 나타내었다. 이러한 결과들을 바탕으로, 바위수국은 항노화(anti-aging) 기능성 화장품 및 이너뷰티 기능성 식품 소재로 개발이 가능할 것으로 기대된다.