• KSBB Journal
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• v.19 no.1
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• pp.27-32
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• 2004

2-Dimensional fluorescence sensor has a wide range of excitation and emission wavelengths, that some biogenic fluorphors in a biological process can be monitored simultaneously. The production processes of 5-aminolevulinic aicd (ALA) by recombinant E. coli BL21 (DE3) pLysS harboring plasmid pFLS45 were on-line monitored by a 2-dimensional fluorescence sensor The characteristics of fluorescence spectrum was dependent upon physical and biological factors of a bioprocess such as culture pH, cell mass etc. Some off-line data were correlated to the fluorescence intensity well, which was monitored at some combination of excitation and emission wavelengths by the 2-dimensional fluorescence sensor.

• The Journal of Pediatrics of Korean Medicine
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• v.24 no.1
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• pp.104-116
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• 2010

Objectives The Medical record consist of symptoms, the cause of a disease, diagnostic studies, medical treatment, prescription, and so on. Doctors can use medical records as data for diagnosis, treatment, and education. Therefore, medical records are beneficial. Methods Translating $\ll$Xiao Er Yao Zheng Zhi Jue$\gg$ into modern Korean, and studying the medical records of Qian Yi(錢乙)'s Medical concept in $\ll$Xiao Er Yao Zheng Zhi Jue$\gg$ were examined. Results Regarding the diagnosis of the pediatric diseases, Si Zhen He Can(四該合參), consider in the eye exam closely. In addition, he closely combined the concept of Wu Zang Bian Zheng(五藏辨證), and diagnosis the pediatric diseases. Wu Zang Bian Zheng(五藏辨證). what Qian-Yi(錢乙) established method was based on Zheng Ti Guan(整體觀) in Huang Di Nei Jing(黃帝內經). Qian-Yi(錢乙) took a close look on Chuang Zhen(瘡疹) which had been an inadequate field in those days. He criticized on the habitual misuse of medications. He treated Ji Jing(急驚) and Man Jing(慢驚) separately; Ji Jing(急驚) as Liang Xie(凉瀉) and Man Jing(慢驚) as Wen Bu(溫補). He proposed Zong Gan Zhu Feng and Xin Zhu Jing(縱肝主風, 心主驚) theory and formulated Jing Feng(驚風) theory as well. He emphasized the treatment to Gong Bu Shang Zheng, Bu Bu Zhi Xie, Xiao Bu Jian Shi(攻不傷正, 補不滯邪, 消補兼施) because he had a clear demonstration to Han Re Xu Shi(寒熱虛實) of the five viscera in the field of Fang yao(方藥). Conclusions Understanding $\ll$Xiao Er Yao Zheng Zhi Jue$\gg$ and its medical records of Qian Yi(錢乙)'s medical concept had quintessential meaning to both modern pediatrician and oriental medical doctors of all medical fields in treating children.

• The Journal of Korean Medical History
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• v.25 no.1
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• pp.43-51
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• 2012

Smallpox and measles might be the typical epidemics through Choson Danasty. Especially Sookjong was the first king who suffered from smallpox during the period of his reign. This study was examined critically focused on the Clinical Records about Smallpox which occurred in the 9th year of Sookjong's reign. The clinical records in Seungjeongwon Ilgi("承政院日記") was the main source and the Annals of the Joseon Dynasty was reffered. It tells us that Sookjong caught infectious disease, smallpox spread in town and the whole process of smallpox. Seungmagalgeuntang(升麻葛根湯) and hwadoktang(火毒湯) were given at the early term for treating Sookjong's smallpox, but later on, Bowontang(補元湯) was given for the treatment of smallpox. It showed us the medical view which placed emphasis on the vital force of human body. A dermatologist, Yoo Sang had joined since the beginning of the treatment and Siyakchung(侍藥廳) was established for Sookjong. Sasunghoichuntang(四聖回天湯) which was Chunyoohyung(全有亨)'s prescription showed us enough clinical experience and the ways of treatments. At the same time, the medical culture at that time was well known through the fact that smallpox was taboo among the royal family.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.6
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• pp.1457-1470
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• 2005

The Medical records (醫案) are very important materials in studying the developmental process of traditional Korean medicine. In this study, we investigated the medical records which are described in Naekyung-pyun(內景篇) of Dongeuibogam(東醫寶鑑), the most famous medical literature in Korean. There are 50 medical records in Naekyung-pyun and all of these records are cited from 12 Chinese medical literatures. The medical records were mainly cited from medical literatures written in Jin-Yuan(金元) and Ming(明) dynasty such as Yixuegangmu(醫學綱目) and Danxizanyao(丹溪纂要), although most records were written by medical scholars in Jin-Yuan(金元) dynasty, including Zhudanxi(朱丹溪) and Zhangzihe(張子和). Most of records were omitted and/or modified reflecting the Purpose of editors of Dongeuibogam. In addition, medical essay(醫論) was changed into medical record in some cases. The authors of the records used oral medication, acupuncture-moxa, psychological treatment and surgical manners. And in some cases of only having principal of treatment, the editors newly added the herbal prescription. The further study on medical records in Korean traditional medicinal literatures, would reveal the developmental progress of Korean medicine and inform more actual proof on medical condition.

• Journal of Aquaculture
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• v.13 no.1
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• pp.47-53
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• 2000

Hormone induction in maturation and ovulation was carried out with spotted halibut (Verasper variegatus) which normally does not spawn spontaneously in captivity. Prior to spawning females were treated with human chorionic gonadotropin(HCG 265-678 IU/kg BM) 17 ${\alpha}$-hydroxy 20-${\beta}$-dihydroprogesterone (17 ${\alpha}$ 20${\beta}$ OHP 0.5-1.0${\mu}$g/kg BW) and luteinizing hormone-releasing hormone analogue pellet (LHRHa pellet 63-81 ${\mu}$g/kg BW) In all the trials HCG injection succeeded in inducing ovulation at 265-300 IU/kg BW. HCG at 620 or 678 IU/kg BW was ineffective in inducing a good rate of ovulation. Final maturation and ovulation were not stimulated by treatment of 17 ${\alpha}$ 20${\beta}$OHP and LHRHa pellet. These results suggest that HCG injection (around 300 IU/kg BW) is more effective compared with LHRHa pellet implantation.

• Journal of Digital Convergence
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• v.14 no.6
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• pp.347-353
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• 2016

Dry eye symptoms can occur by various environmental exposure. This study aimed to investigate the relationship between eye symptom especially dry eye and sunblocks. Study subjects were total 30 (28 male, 2 female) and NIBUT, McMonnies dry eye questionnaire, subjective questionnaire were performed. NIBUT after rubbing sunblocks was decreased compared to that of not-rubbing. Sunblocks C showed the largest difference of NIBUT value and was chosen most uncomfortable sunblocks in subjective questionnaire. Half of the subjects (15) felt eyes discomfort after rubbing sunblocks and showed larger McMonnies dry eye questionnaire score than other subjects. The same result was founded about dry eye suspect criterion. Both showed borderline significant relation(p=0.049, p=0.051). This study suggested that sunblock could cause damage to the eyes and related to dry eye when rubbing sunblock around eyes. Because digital environmental factors could affect stimulus and modify the eyes, a convergence study will be required for additional research.

• The Journal of Korean Medical History
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• v.18 no.1
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• pp.23-47
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• 2005

The study is written for the purpose of examining Na Cheon Ik(羅天益)'s medical ideology mentioned in Euian(醫案) of "Wi-saeng-bo-gam 衛生寶鑑". The publication of this book is reflected in the 13th century perplexed conditions. In this thesis, after the writer analyzed Na Cheon Ik(羅天益)'s medical theory in "Wi-saeng-bo-gam 衛生寶鑑", knew that he emphasized practical use on all occasions. So far, Na Cheon Ik(羅天益)'s medical ideology in "Wi-saeng-bo-gam 衛生 寶鑑" is hardly studied. "Wi-saeng-bo-gam 衛生寶鑑" is a medical book which was written in the process of systemic recognized of medical theories of various and special academic parties in the period J inYuan(金元). The medical theory that appears in "Wi-saeng-bo-gam 衛生寶鑑" is rooted in Li Dong Yuan(李東垣)'s theory, but also Na Cheon Ik(羅天益)'s medical ideology is distinguished from Li Dong Won(李東垣)'s ideology. First of all, Na Cheon Ik(羅天 益) recognized the importance of discerning not only On-Bo(溫補) but also Han-Ha-To(汗下吐) and various ways in medical treatment. Secondly, the fact that Na Cheon Ik(羅天益) made good use of moxibustion tells the difference between the two. In conclusion, "Wi-saeng-bo-gam 衛生寶鑑" holds systemic medical information which was originated with Na Cheon Ik(羅天益)'s various and special experience. He had contributed in the clinical experience and medical information by having an effect on the ages to come.

• The Journal of Korean Medical History
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• v.29 no.1
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• pp.79-87
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• 2016

Queen Jangyeol was proclaimed as the second wife of King Injo at the age of 15 in 1638. This study was carried out in order to confirm if Queen Jangyeol actually came down with epilepsy or if she pretended to do. The keywords, "Jungjeon" and "Junggungjeon" were searched among the articles from "Seungjeongwonilgi" in the 16th reign to the 27th reign of King Injo. After that, articles only related to convulsion were selected. The symptom of convulsion and the therapy were analyzed. King Injo gave an order, and royal doctors diagnosed the queen's illness as epilepsy in August in the 23th reign. The Queen was confined in Gyeongdeok in November, and took herbal drugs for treating the epilepsy. After the death of King Injo, she stopped taking the drugs. As the Queen's epilepsy took place consistently more than 1~2 times in a month, it is the generalized tonic-clonic seizure. Also, it is the epilepsy overlapping reiteration with the brain function disorder because the convulsion lasted throughout 1 hour. However, after King Injo died, she lived for long without the brain function disorder. So it is difficult to judge she actually came down with the epilepsy.

• The Journal of Korean Medical History
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• v.30 no.1
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• pp.51-59
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• 2017

Shihosamul-tang (柴胡四物湯, Bupleurum Four Substances Decoction) is a very effective and widely utilized prescription in Korean medicine. However, there has not been a clinical example written in the classical literature of Korean medicine that deals with Shihosamul-tang and the delicate and changeable clinical use of Shihosamul-tang remains unknown. This study tries, for the first time, to show the clinical practice of Shihosamul-tang through review of KyungBoSinPyun (輕寶新篇). KyungBoSinPyun is a medical book containing 143 case records in the tradition of the East Asian practice of describing clinical encounters and the therapies employed. This study examines eight examples of case records within KyungBoSinPyun highlighting use of Shihosamul-tang. The purpose is to understand how Shihosamul-tang is applied in clinical practice compared to the description of Shihosamul-tang in Donguibogam (東醫寶鑑). Different descriptions about the symptoms and transformation methods of the prescription have been found in the eight examples of Shihosamul-tang case records contained in KyungBoSinPyun. This paper concludes that the difference between clinical practice and a typical description in medical books should be overcome by medical virtuosity and the potential for change for each clinical case, which is gained when seeing beyond the text of medical books.

• Proceedings of the KSR Conference
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• 2008.11b
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• pp.441-445
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• 2008

LRT is eco-friendly transportation system and can be constructed at less than half cost of subway. Therefore many local governments have planned to construct a various type of LRT and some of them were already under construction. In Para. 2 of Art. 22 of the "Enforcement Decree of Urban Railroad Act" - safety standard of urban railroad vehicle, It can't be operated if "structures and devices" don't come up to standard required to safety operation. Constructor or operator should give an order or operate according to safety standard in Art. 3 of the Safety Standard of Urban Railroad Vehicle. Safety Standard of Urban Railroad Vehicle of 2000 was reformed once to tighten fire safety standard in 2004 after subway accident in Daegue. It was entirely made for medium and large-sized electric motor car. LRT, based on driverless operation and articulated bogie, has different safety standard in signalling devices and the axle load. etc. So many institutes related LRT have required to amend. In this paper, we described features of LRT vehicle and necessity of amendment and discussed how it should be amended.